The gene/protein map for NC_005823 is currently unavailable.
Definition Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence.
Accession NC_005823
Length 4,277,185

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The map label for this gene is mlr

Identifier: 45656569

GI number: 45656569

Start: 816379

End: 817143

Strand: Direct

Name: mlr

Synonym: LIC10671

Alternate gene names: 45656569

Gene position: 816379-817143 (Clockwise)

Preceding gene: 45656567

Following gene: 45656573

Centisome position: 19.09

GC content: 38.43

Gene sequence:

>765_bases
ATGCCTAGTTCCGATAAAGCCATAGAAATTCAAAAATTAAATCTCCGATTGGGTCAAAGGATAATCTTAGATTCGATTTC
TTTCGAAGTGAATTCCGGAACGATACTTGGAATTTTAGGTCGTTCCGGTTCAGGTAAAACTTCTCTTTTCCGAGCGATTT
TAGGAGTTCCTACAACCACGAATCTGGAACAAAGCGGATCGATTTATTTTTTTGGAAAGGCCCGAAAAGAAATTCCGATC
CATCATTTACAACCAGTCTTTCAAGATCCTGTCGGAAGTTTCAACCCTGCCTGGTCTTTGGAAAAAGCTTTGAAAGAACC
ACTCCGAATTTTAGGGGGAGAAATTGCAAATAGGGGAGAGGCTTTTTTCCCAGATTTACTAGAGTCTTTTCGGTTGGCAA
ATAAAGATCTCAATCGAAATGTACTTTCTTTTTCCGGAGGTGAACTACAAAGGGCAGCGATTCTTCGCGCTCTTCTTACT
GAACCTAAGATTCTTTTTTTGGACGAGGCATTAGGTGCTTTGGATCCAATCCTTTTGAACGATGTATTACAATTTTTAAA
GAGGATTTCCAGGGAAAGGAAAATTACGATTTTATTAATTACTCATAGTTTGAGGACGGCTCAAAAATTCTGCAATCAAA
TTGGAATATTAGAAAAAGGTAAATTATTAGATTTTGGAACAACGGAAGAAGTGTTTACGAATTATAAAAGTTCTTTTACG
GGGGAACTCATTCGTGCGATCGATTTGAGTTCCCTCCGCGCTTGA

Upstream 100 bases:

>100_bases
CATCGAACTCACGTCGGAGTTAATATCTTTTACAACGTGAGAGCTCCCACATTTTTAAGAATTCTTGTTTTAAAAAAAGG
ATAATTCTACTTTGTAAGAA

Downstream 100 bases:

>100_bases
TCAGATGTCGATCTGATAGAGATTTTTTCTGTCTTTTTTGTCTTTGTAAAGTGCGATCATAATATCGATTCGGTAGATCG
AAGATCTGAGGCTAGACTCT

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MPSSDKAIEIQKLNLRLGQRIILDSISFEVNSGTILGILGRSGSGKTSLFRAILGVPTTTNLEQSGSIYFFGKARKEIPI
HHLQPVFQDPVGSFNPAWSLEKALKEPLRILGGEIANRGEAFFPDLLESFRLANKDLNRNVLSFSGGELQRAAILRALLT
EPKILFLDEALGALDPILLNDVLQFLKRISRERKITILLITHSLRTAQKFCNQIGILEKGKLLDFGTTEEVFTNYKSSFT
GELIRAIDLSSLRA

Sequences:

>Translated_254_residues
MPSSDKAIEIQKLNLRLGQRIILDSISFEVNSGTILGILGRSGSGKTSLFRAILGVPTTTNLEQSGSIYFFGKARKEIPI
HHLQPVFQDPVGSFNPAWSLEKALKEPLRILGGEIANRGEAFFPDLLESFRLANKDLNRNVLSFSGGELQRAAILRALLT
EPKILFLDEALGALDPILLNDVLQFLKRISRERKITILLITHSLRTAQKFCNQIGILEKGKLLDFGTTEEVFTNYKSSFT
GELIRAIDLSSLRA
>Mature_253_residues
PSSDKAIEIQKLNLRLGQRIILDSISFEVNSGTILGILGRSGSGKTSLFRAILGVPTTTNLEQSGSIYFFGKARKEIPIH
HLQPVFQDPVGSFNPAWSLEKALKEPLRILGGEIANRGEAFFPDLLESFRLANKDLNRNVLSFSGGELQRAAILRALLTE
PKILFLDEALGALDPILLNDVLQFLKRISRERKITILLITHSLRTAQKFCNQIGILEKGKLLDFGTTEEVFTNYKSSFTG
ELIRAIDLSSLRA

Specific function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system [H]

COG id: COG1123

COG function: function code R; ATPase components of various ABC-type transport systems, contain duplicated ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI171184400, Length=228, Percent_Identity=31.140350877193, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27436953, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI148612844, Length=225, Percent_Identity=31.5555555555556, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI11967969, Length=227, Percent_Identity=29.9559471365639, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI255708477, Length=228, Percent_Identity=32.0175438596491, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI27262624, Length=228, Percent_Identity=22.8070175438596, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI27262626, Length=228, Percent_Identity=22.8070175438596, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI42741659, Length=224, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1789891, Length=215, Percent_Identity=31.6279069767442, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1788506, Length=232, Percent_Identity=31.4655172413793, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787500, Length=244, Percent_Identity=29.9180327868852, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI145693107, Length=235, Percent_Identity=29.3617021276596, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1789962, Length=234, Percent_Identity=28.6324786324786, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI48994883, Length=242, Percent_Identity=29.3388429752066, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787758, Length=220, Percent_Identity=28.1818181818182, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786398, Length=242, Percent_Identity=31.8181818181818, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787089, Length=245, Percent_Identity=31.0204081632653, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789963, Length=255, Percent_Identity=26.2745098039216, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788225, Length=253, Percent_Identity=28.0632411067194, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788761, Length=251, Percent_Identity=30.6772908366534, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787759, Length=258, Percent_Identity=25.5813953488372, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081791, Length=253, Percent_Identity=27.6679841897233, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI48994997, Length=227, Percent_Identity=27.3127753303965, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787712, Length=240, Percent_Identity=28.3333333333333, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787548, Length=241, Percent_Identity=26.5560165975104, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787370, Length=232, Percent_Identity=28.0172413793103, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787029, Length=248, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87081709, Length=245, Percent_Identity=27.3469387755102, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789890, Length=243, Percent_Identity=25.9259259259259, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI48994943, Length=245, Percent_Identity=28.1632653061224, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788644, Length=254, Percent_Identity=29.5275590551181, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789593, Length=236, Percent_Identity=29.2372881355932, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786698, Length=206, Percent_Identity=30.0970873786408, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789032, Length=251, Percent_Identity=27.0916334661355, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787547, Length=224, Percent_Identity=24.5535714285714, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87081782, Length=244, Percent_Identity=28.6885245901639, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87081834, Length=213, Percent_Identity=30.5164319248826, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1790467, Length=242, Percent_Identity=25.6198347107438, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786563, Length=214, Percent_Identity=32.2429906542056, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788450, Length=235, Percent_Identity=24.6808510638298, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787112, Length=224, Percent_Identity=31.6964285714286, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1789672, Length=252, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786319, Length=235, Percent_Identity=28.5106382978723, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786345, Length=239, Percent_Identity=26.7782426778243, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87082268, Length=242, Percent_Identity=26.8595041322314, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082267, Length=234, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786703, Length=236, Percent_Identity=29.2372881355932, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787164, Length=204, Percent_Identity=27.4509803921569, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788053, Length=200, Percent_Identity=28.5, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786253, Length=227, Percent_Identity=26.431718061674, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788165, Length=230, Percent_Identity=28.2608695652174, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786803, Length=237, Percent_Identity=24.0506329113924, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786872, Length=110, Percent_Identity=30.9090909090909, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790739, Length=242, Percent_Identity=23.1404958677686, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790162, Length=97, Percent_Identity=29.8969072164948, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI2367384, Length=207, Percent_Identity=28.0193236714976, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1786981, Length=216, Percent_Identity=33.7962962962963, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=236, Percent_Identity=30.0847457627119, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25146777, Length=229, Percent_Identity=31.8777292576419, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17543740, Length=222, Percent_Identity=29.2792792792793, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193208177, Length=217, Percent_Identity=30.4147465437788, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17533971, Length=226, Percent_Identity=26.9911504424779, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551702, Length=239, Percent_Identity=27.1966527196653, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551700, Length=239, Percent_Identity=27.1966527196653, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=247, Percent_Identity=29.1497975708502, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=245, Percent_Identity=29.3877551020408, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193211015, Length=245, Percent_Identity=29.3877551020408, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71983516, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=215, Percent_Identity=27.906976744186, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=223, Percent_Identity=30.9417040358744, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569081, Length=245, Percent_Identity=28.9795918367347, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193202349, Length=229, Percent_Identity=26.2008733624454, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=227, Percent_Identity=27.7533039647577, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=219, Percent_Identity=29.6803652968037, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=213, Percent_Identity=24.8826291079812, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115532730, Length=204, Percent_Identity=29.9019607843137, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17567269, Length=217, Percent_Identity=29.4930875576037, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6324985, Length=226, Percent_Identity=26.9911504424779, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322640, Length=230, Percent_Identity=26.5217391304348, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573571, Length=224, Percent_Identity=27.6785714285714, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573573, Length=224, Percent_Identity=27.6785714285714, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI85725262, Length=212, Percent_Identity=29.7169811320755, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI23397593, Length=229, Percent_Identity=30.5676855895196, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI85726357, Length=222, Percent_Identity=27.4774774774775, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24643674, Length=260, Percent_Identity=23.4615384615385, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574533, Length=227, Percent_Identity=26.431718061674, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24648314, Length=212, Percent_Identity=25.9433962264151, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015858
- InterPro:   IPR003593
- InterPro:   IPR014137 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.24 [H]

Molecular weight: Translated: 28192; Mature: 28061

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MPSSDKAIEIQKLNLRLGQRIILDSISFEVNSGTILGILGRSGSGKTSLFRAILGVPTTT
CCCCCCEEEEEEHHHHHCHHHHHHHHEEEECCCEEEEEEECCCCCHHHHHHHHHCCCCCC
NLEQSGSIYFFGKARKEIPIHHLQPVFQDPVGSFNPAWSLEKALKEPLRILGGEIANRGE
CCCCCCCEEEEECCCCCCCHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHCCCC
AFFPDLLESFRLANKDLNRNVLSFSGGELQRAAILRALLTEPKILFLDEALGALDPILLN
CHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHH
DVLQFLKRISRERKITILLITHSLRTAQKFCNQIGILEKGKLLDFGTTEEVFTNYKSSFT
HHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHH
GELIRAIDLSSLRA
HHHHHHHHHHHHCC
>Mature Secondary Structure 
PSSDKAIEIQKLNLRLGQRIILDSISFEVNSGTILGILGRSGSGKTSLFRAILGVPTTT
CCCCCEEEEEEHHHHHCHHHHHHHHEEEECCCEEEEEEECCCCCHHHHHHHHHCCCCCC
NLEQSGSIYFFGKARKEIPIHHLQPVFQDPVGSFNPAWSLEKALKEPLRILGGEIANRGE
CCCCCCCEEEEECCCCCCCHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHCCCC
AFFPDLLESFRLANKDLNRNVLSFSGGELQRAAILRALLTEPKILFLDEALGALDPILLN
CHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHH
DVLQFLKRISRERKITILLITHSLRTAQKFCNQIGILEKGKLLDFGTTEEVFTNYKSSFT
HHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHH
GELIRAIDLSSLRA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]