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The map label for this gene is sp

Identifier: 45656573

GI number: 45656573

Start: 820165

End: 820887

Strand: Direct

Name: sp

Synonym: LIC10675

Alternate gene names: 45656573

Gene position: 820165-820887 (Clockwise)

Preceding gene: 45656569

Following gene: 45656574

Centisome position: 19.18

GC content: 38.17

Gene sequence:

>723_bases
TTGGAGAATCCGTGCCCTAAAAAACGCATTGTAAATTCTGTTTCCAAAGGGATTCTGGCATCACAAAGAGGAATCGTTTT
GCCGCCTAACGAACAAGCGCTTTTCGTCTGCAAGGATCTATCTTATTCTATCGGAAAAAAAAAGATTCTCAAACAGGTTT
CATTTTCTATTTTCCGAGGTGAAATTTCTCTTCTAAGAGGAGATAACGGAGCTGGCAAAACCACTCTTCTTCGAGCAATT
CTCAATCACGATCGTCATAAGAATTGTTTTACGTTTCAAAACCGCTTATCGGCTGTAAAAATCTCTTATTTAGGACATGA
GCTCGGGCTTTATACTTCTCTCAGTCTTGAAGAGAATCTTCGTTATTTTCTTTCCATTGCTAAAATCCAATATTCGAAAG
AAAAAGTGGAAACACTTCTTAGAGCCTTCCAACTTTGGACAAGAAGATTGGATCCGATTTTTACTTTTTCAAGAGGAATG
AAACAAAAAGCGGCTTTAGTTCGTACACTTTTAACCGGAGGAGATCTGATTCTTTTGGATGAACCTTTTACAGCTCTGGA
TCGATCCGGATTAGAAACTGCAATTCGTCTTTTAAACGAATACTCGCAAAACTCCGCAGTTCTTATGGTAACTCATGATC
CTGGAATTTCTTTCGGACGACGTACTGTTTCTTTAACTTTAAAGGAGGGAAATCTTGAAACTTCTATTCTCTCTTCTCCA
TAA

Upstream 100 bases:

>100_bases
ACCTCACAAAGTTGTAAGATCAATTGTAAAATGTGGGAACCACCACAAAGTGCAATTCTTGAGATTGTAAAGTCTCCTTC
AAAGTTCCTTTCAAAACGAT

Downstream 100 bases:

>100_bases
GGAATTTCTGTTATTAGGAAAAGCGATCAACGGAATTCTTTCCGTATTAGTTTTGATCACTTCAATCGTATTCATTTTTA
ATTATGCATTAGAACAGACA

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MENPCPKKRIVNSVSKGILASQRGIVLPPNEQALFVCKDLSYSIGKKKILKQVSFSIFRGEISLLRGDNGAGKTTLLRAI
LNHDRHKNCFTFQNRLSAVKISYLGHELGLYTSLSLEENLRYFLSIAKIQYSKEKVETLLRAFQLWTRRLDPIFTFSRGM
KQKAALVRTLLTGGDLILLDEPFTALDRSGLETAIRLLNEYSQNSAVLMVTHDPGISFGRRTVSLTLKEGNLETSILSSP

Sequences:

>Translated_240_residues
MENPCPKKRIVNSVSKGILASQRGIVLPPNEQALFVCKDLSYSIGKKKILKQVSFSIFRGEISLLRGDNGAGKTTLLRAI
LNHDRHKNCFTFQNRLSAVKISYLGHELGLYTSLSLEENLRYFLSIAKIQYSKEKVETLLRAFQLWTRRLDPIFTFSRGM
KQKAALVRTLLTGGDLILLDEPFTALDRSGLETAIRLLNEYSQNSAVLMVTHDPGISFGRRTVSLTLKEGNLETSILSSP
>Mature_240_residues
MENPCPKKRIVNSVSKGILASQRGIVLPPNEQALFVCKDLSYSIGKKKILKQVSFSIFRGEISLLRGDNGAGKTTLLRAI
LNHDRHKNCFTFQNRLSAVKISYLGHELGLYTSLSLEENLRYFLSIAKIQYSKEKVETLLRAFQLWTRRLDPIFTFSRGM
KQKAALVRTLLTGGDLILLDEPFTALDRSGLETAIRLLNEYSQNSAVLMVTHDPGISFGRRTVSLTLKEGNLETSILSSP

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG1116

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI153792144, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1788165, Length=183, Percent_Identity=31.1475409836066, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788761, Length=213, Percent_Identity=30.0469483568075, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786698, Length=215, Percent_Identity=27.4418604651163, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787105, Length=209, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081782, Length=195, Percent_Identity=25.6410256410256, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI87082064, Length=180, Percent_Identity=31.1111111111111, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789873, Length=208, Percent_Identity=27.4038461538462, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48995001, Length=201, Percent_Identity=27.8606965174129, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325030, Length=196, Percent_Identity=29.0816326530612, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666092, Length=211, Percent_Identity=27.9620853080569, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 26918; Mature: 26918

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENPCPKKRIVNSVSKGILASQRGIVLPPNEQALFVCKDLSYSIGKKKILKQVSFSIFRG
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHC
EISLLRGDNGAGKTTLLRAILNHDRHKNCFTFQNRLSAVKISYLGHELGLYTSLSLEENL
EEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHEEEHHHHHHHHCCEEECCHHHHH
RYFLSIAKIQYSKEKVETLLRAFQLWTRRLDPIFTFSRGMKQKAALVRTLLTGGDLILLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHCCCCEEEEC
EPFTALDRSGLETAIRLLNEYSQNSAVLMVTHDPGISFGRRTVSLTLKEGNLETSILSSP
CCHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCEECCCC
>Mature Secondary Structure
MENPCPKKRIVNSVSKGILASQRGIVLPPNEQALFVCKDLSYSIGKKKILKQVSFSIFRG
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHC
EISLLRGDNGAGKTTLLRAILNHDRHKNCFTFQNRLSAVKISYLGHELGLYTSLSLEENL
EEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHEEEHHHHHHHHCCEEECCHHHHH
RYFLSIAKIQYSKEKVETLLRAFQLWTRRLDPIFTFSRGMKQKAALVRTLLTGGDLILLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHCCCCEEEEC
EPFTALDRSGLETAIRLLNEYSQNSAVLMVTHDPGISFGRRTVSLTLKEGNLETSILSSP
CCHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]