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The map label for this gene is trpG

Identifier: 45656479

GI number: 45656479

Start: 707118

End: 707696

Strand: Reverse

Name: trpG

Synonym: LIC10581

Alternate gene names: 45656479

Gene position: 707696-707118 (Counterclockwise)

Preceding gene: 45656480

Following gene: 45656478

Centisome position: 16.55

GC content: 37.65

Gene sequence:

>579_bases
ATGTTTCTCCTGATCGATAATTACGATTCTTTCACATACAATCTTTATCAATATTTTTCTCAGATAGGAAATGAAATCGA
AGTTTATCGTAACGATAAAATTACGTTAGACGAAATTAAACATCTCTCGCCAAAAGCAATCATTTTATCTCCTGGTCCAG
GCCGCCCGGAAGATTCTAAAGTTTGTTTGGATGTAATTCGTGAATTAGGAGGTAAACTTCCTATCTTAGGAGTTTGCCTC
GGACATCAAGCAATCGGTCTTGTTCACGGAGGTAAAATTGTATCTGCTCCTTCTATCATGCACGGAAAAATTTCTCTTGT
AGAACACGACGGAAAAGACATTTATAAAGGAATCTCCTCTCCTTTTGTGGCGACTCGTTATCATTCTCTTGTAATACAAC
CAGAAAGTCTACCTAAGGAACTCGAAATTGCTTCTAAAACTCCCGATGGAGTAATTATGGGAGTTCGTCATAAAACTAAA
AAACATCTTTATGGAGTTCAATTTCATCCAGAGTCCATCATGACCGGTGCCGGTTTGGATTTAATTAGAAACTTTTCATC
CATCGTTCAGGAGCTATGA

Upstream 100 bases:

>100_bases
CGGTTCCAGAGTTGGAATTAGAAGAAACGAAAAATAAAATGGCAGCGCTTTTAAAAGCGGTAGAGTTCGCAAGAAATGGA
CTCAAAGGAGAATGGAAATA

Downstream 100 bases:

>100_bases
AGTTTTTTTTTAGGCTCTTATCTTACTCTGTACATTATAAATATCGATTTACGTTAGGAATCGTATTCGCGTTGTTAACC
GCAATTTTAAACGCGGTTTC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MFLLIDNYDSFTYNLYQYFSQIGNEIEVYRNDKITLDEIKHLSPKAIILSPGPGRPEDSKVCLDVIRELGGKLPILGVCL
GHQAIGLVHGGKIVSAPSIMHGKISLVEHDGKDIYKGISSPFVATRYHSLVIQPESLPKELEIASKTPDGVIMGVRHKTK
KHLYGVQFHPESIMTGAGLDLIRNFSSIVQEL

Sequences:

>Translated_192_residues
MFLLIDNYDSFTYNLYQYFSQIGNEIEVYRNDKITLDEIKHLSPKAIILSPGPGRPEDSKVCLDVIRELGGKLPILGVCL
GHQAIGLVHGGKIVSAPSIMHGKISLVEHDGKDIYKGISSPFVATRYHSLVIQPESLPKELEIASKTPDGVIMGVRHKTK
KHLYGVQFHPESIMTGAGLDLIRNFSSIVQEL
>Mature_192_residues
MFLLIDNYDSFTYNLYQYFSQIGNEIEVYRNDKITLDEIKHLSPKAIILSPGPGRPEDSKVCLDVIRELGGKLPILGVCL
GHQAIGLVHGGKIVSAPSIMHGKISLVEHDGKDIYKGISSPFVATRYHSLVIQPESLPKELEIASKTPDGVIMGVRHKTK
KHLYGVQFHPESIMTGAGLDLIRNFSSIVQEL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=51.3513513513513, Blast_Score=212, Evalue=1e-56,
Organism=Escherichia coli, GI1787517, Length=192, Percent_Identity=40.1041666666667, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786215, Length=142, Percent_Identity=29.5774647887324, Blast_Score=70, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322638, Length=187, Percent_Identity=48.1283422459893, Blast_Score=184, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6324361, Length=206, Percent_Identity=33.0097087378641, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 21264; Mature: 21264

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLLIDNYDSFTYNLYQYFSQIGNEIEVYRNDKITLDEIKHLSPKAIILSPGPGRPEDSK
CEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCEEHHHHHCCCCCEEEECCCCCCCCCHH
VCLDVIRELGGKLPILGVCLGHQAIGLVHGGKIVSAPSIMHGKISLVEHDGKDIYKGISS
HHHHHHHHHCCCCCEEEEECCCHHEEEEECCEEEECCCEECCEEEEEECCCHHHHHHCCC
PFVATRYHSLVIQPESLPKELEIASKTPDGVIMGVRHKTKKHLYGVQFHPESIMTGAGLD
CEEEEEEEEEEECCCCCCCHHHHCCCCCCCEEEECCHHHHHHEECEEECCHHHHCCCCHH
LIRNFSSIVQEL
HHHHHHHHHHHC
>Mature Secondary Structure
MFLLIDNYDSFTYNLYQYFSQIGNEIEVYRNDKITLDEIKHLSPKAIILSPGPGRPEDSK
CEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCEEHHHHHCCCCCEEEECCCCCCCCCHH
VCLDVIRELGGKLPILGVCLGHQAIGLVHGGKIVSAPSIMHGKISLVEHDGKDIYKGISS
HHHHHHHHHCCCCCEEEEECCCHHEEEEECCEEEECCCEECCEEEEEECCCHHHHHHCCC
PFVATRYHSLVIQPESLPKELEIASKTPDGVIMGVRHKTKKHLYGVQFHPESIMTGAGLD
CEEEEEEEEEEECCCCCCCHHHHCCCCCCCEEEECCHHHHHHEECEEECCHHHHCCCCHH
LIRNFSSIVQEL
HHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]