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The map label for this gene is 45656305

Identifier: 45656305

GI number: 45656305

Start: 460775

End: 462841

Strand: Direct

Name: 45656305

Synonym: LIC10405

Alternate gene names: NA

Gene position: 460775-462841 (Clockwise)

Preceding gene: 45656304

Following gene: 45656306

Centisome position: 10.77

GC content: 39.86

Gene sequence:

>2067_bases
ATGGATAAAGAAATCCGAAAAAACAGGTTGTTTTTAGAGGGAATCGAGGAAGAGGAATTTTATTTCCCCGAGAATAAAGA
ACCGGTTCGGATTCGTAGATCCTATAATAAACTTCTAATATTCTGGATTCTGATGGGTCTTTTGGTGTTAGGGGGAATCG
GTTTTGCGGTTTACCATCAATTTTTTCGTAATTCCTCCTCTGGTTCCGAGTTTGCAGGAGCCTTTAATAAGGATTTGATC
CAAAATAAATCCGACATCAATCGTTTATTAGAAAGACCTTATATACCGGATGGAAACGCAAACCCGGCGTTAACAAAATG
TATCAATCTTTACAAAGAAAGATTTACCAGGCAGGCATTTGATACCTGTAATGAGTTTTTAGATTCTACAGGAACTCAGG
AAGAAAAATCGATCGCATTGACTGTGTTAGGTGTAATCCATGACGAGAGCGGGCGTTATCCGCAAGCAATCGAAAGACTT
CAAAAAGCGATTCAATACGATCCTAAAAATTTCTACGCGTATTACAATCTTACGTTGTCTTATAAACACGCTGGAAGATT
TGCAGACGCTCGAATGGCTGCTCTGAAAGCGAAAGAAATCGCGCCTAGTGATCCTAGGGTTTCGTTACTTGCTGGAAATC
TATTTAACGAGTTGAACGACCCGGATGCTGCGATTGACGCCTATAAAGAAGGGTTGTCTACTTCTCCGGACGATATGCAT
CTGACTTACAATTTAGGAGTTAGTTATTTTAAAAAGGGTGAAATTCCACAAGCAGAAGAGGAATTTAAGAAAGTTGTAAT
AAAGACTCCATCCGGAAGATTAGCCGCGTTATCTCATTCTTATTTGGGAAATATCGCTTACAACAAACAGGATTATAAAA
ATGCGGAATATCATTTCCGACAAGCAAGCAACCTTTCACCTAACGAAGCAAAGTATCTTTATAATCTCGCGATAGTTCTA
CAAAAAAATGGAAATAAAGAAGAGGCTCTTAAATATTTGGAACTTGCGAGAGACGCAGGCGCAAACGATCCCGAAATTTA
TAGATTGATTGCAGAAGGGTTTTCCAATCTCAATCAGGGAGAGATGTCCATTTCGGCGCTTCAGAAAAGTTTAAAATATA
ATCCTACGGATGTGGATTCTCTCTTTCAACTTGCGGAAGCATACTATAACAAAGGAGATTTACTTTCTGCGGAAGAAACC
TATCGTAGGATCGTATCTTCTACTCCTGGCGATAGTTTTACGGAGACTGCTCTGATTAATTTGGGAGTCGTTTTGGATCA
GATGGAACGTTATGGAGAAGCGGTCACTACTTTGAATCGGGTGATAGAACTCAATCCTAAAAACGCGAAAGCGTATCATA
CATTAGGAATTGTTTATAAACATTCTGGAAATGGGACACTCGCTATAGAAAACTGGAGAAAGTCCACGGCGATAGAGCCG
GAAAATATACAAAGCCGTGAAGCTCTTGGAGACTATTTACTGGAAAATAAATTTTTTCGGGAAGCTGTGGAAGAATATAT
AGGATTAGTAAAACATAAAGACGACGCTTACAAGGTATATCTCAAAATGGCGGAAGCCTATATGGGAATGCAGGACGATT
CCAACGCCGAAAAAATTCTACTGAAAGTATTGAATTCTTCAAGAGACGGAGCGGATCTGAAAAACGCGCATAAGAAACTT
GCCTTGTTATATAATAAATCCAAAGACCCAGATTTAAAAAATAGGGCCAAAGACGAGGCTTTTCGCTCTGCTCACATGGA
TCCGAACGATATGGAAGGCAGATTGGTACTTGCAAAAATTCTAATAGATTCTAATTCAATTTTGGATCGTGAAAAGGCTA
TCGATGAACTGACCGCGATTGTGAGATCTGATGTAAGACCTAAAACAGCGGCGACCGCTTATAATTATTTAGGGATTTGT
TATTATAAAAATGGGGAATTTAAAAGGGCGGTTCGGGCGTTTCAGAGTTCGATCGATTTAGACCCGTCTTTGTCAGAAGC
CTACGAGAATAAGCGGGCAGCGTCTGCGGCGTTAGAAGAAAATACTCGCAGGGAGGGATATTTCTGA

Upstream 100 bases:

>100_bases
GACGAAGCGGTAGAACTTACAAAAGAATTTGAAAGCGAAGAATCGGCTCGGTTTGTAAACGGAGTTTTGGACGCAATTCT
CAAAAACGAAATCAAATCCG

Downstream 100 bases:

>100_bases
AAAGTTACTTCTTAACGTTTTTGATTTCATTCCTTTTTATAACTTCGATTCAAGCAGCGGAAACACCTAAAGACGAATTT
AAAGAAAAAGTATTCAATTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 688

Protein sequence:

>688_residues
MDKEIRKNRLFLEGIEEEEFYFPENKEPVRIRRSYNKLLIFWILMGLLVLGGIGFAVYHQFFRNSSSGSEFAGAFNKDLI
QNKSDINRLLERPYIPDGNANPALTKCINLYKERFTRQAFDTCNEFLDSTGTQEEKSIALTVLGVIHDESGRYPQAIERL
QKAIQYDPKNFYAYYNLTLSYKHAGRFADARMAALKAKEIAPSDPRVSLLAGNLFNELNDPDAAIDAYKEGLSTSPDDMH
LTYNLGVSYFKKGEIPQAEEEFKKVVIKTPSGRLAALSHSYLGNIAYNKQDYKNAEYHFRQASNLSPNEAKYLYNLAIVL
QKNGNKEEALKYLELARDAGANDPEIYRLIAEGFSNLNQGEMSISALQKSLKYNPTDVDSLFQLAEAYYNKGDLLSAEET
YRRIVSSTPGDSFTETALINLGVVLDQMERYGEAVTTLNRVIELNPKNAKAYHTLGIVYKHSGNGTLAIENWRKSTAIEP
ENIQSREALGDYLLENKFFREAVEEYIGLVKHKDDAYKVYLKMAEAYMGMQDDSNAEKILLKVLNSSRDGADLKNAHKKL
ALLYNKSKDPDLKNRAKDEAFRSAHMDPNDMEGRLVLAKILIDSNSILDREKAIDELTAIVRSDVRPKTAATAYNYLGIC
YYKNGEFKRAVRAFQSSIDLDPSLSEAYENKRAASAALEENTRREGYF

Sequences:

>Translated_688_residues
MDKEIRKNRLFLEGIEEEEFYFPENKEPVRIRRSYNKLLIFWILMGLLVLGGIGFAVYHQFFRNSSSGSEFAGAFNKDLI
QNKSDINRLLERPYIPDGNANPALTKCINLYKERFTRQAFDTCNEFLDSTGTQEEKSIALTVLGVIHDESGRYPQAIERL
QKAIQYDPKNFYAYYNLTLSYKHAGRFADARMAALKAKEIAPSDPRVSLLAGNLFNELNDPDAAIDAYKEGLSTSPDDMH
LTYNLGVSYFKKGEIPQAEEEFKKVVIKTPSGRLAALSHSYLGNIAYNKQDYKNAEYHFRQASNLSPNEAKYLYNLAIVL
QKNGNKEEALKYLELARDAGANDPEIYRLIAEGFSNLNQGEMSISALQKSLKYNPTDVDSLFQLAEAYYNKGDLLSAEET
YRRIVSSTPGDSFTETALINLGVVLDQMERYGEAVTTLNRVIELNPKNAKAYHTLGIVYKHSGNGTLAIENWRKSTAIEP
ENIQSREALGDYLLENKFFREAVEEYIGLVKHKDDAYKVYLKMAEAYMGMQDDSNAEKILLKVLNSSRDGADLKNAHKKL
ALLYNKSKDPDLKNRAKDEAFRSAHMDPNDMEGRLVLAKILIDSNSILDREKAIDELTAIVRSDVRPKTAATAYNYLGIC
YYKNGEFKRAVRAFQSSIDLDPSLSEAYENKRAASAALEENTRREGYF
>Mature_688_residues
MDKEIRKNRLFLEGIEEEEFYFPENKEPVRIRRSYNKLLIFWILMGLLVLGGIGFAVYHQFFRNSSSGSEFAGAFNKDLI
QNKSDINRLLERPYIPDGNANPALTKCINLYKERFTRQAFDTCNEFLDSTGTQEEKSIALTVLGVIHDESGRYPQAIERL
QKAIQYDPKNFYAYYNLTLSYKHAGRFADARMAALKAKEIAPSDPRVSLLAGNLFNELNDPDAAIDAYKEGLSTSPDDMH
LTYNLGVSYFKKGEIPQAEEEFKKVVIKTPSGRLAALSHSYLGNIAYNKQDYKNAEYHFRQASNLSPNEAKYLYNLAIVL
QKNGNKEEALKYLELARDAGANDPEIYRLIAEGFSNLNQGEMSISALQKSLKYNPTDVDSLFQLAEAYYNKGDLLSAEET
YRRIVSSTPGDSFTETALINLGVVLDQMERYGEAVTTLNRVIELNPKNAKAYHTLGIVYKHSGNGTLAIENWRKSTAIEP
ENIQSREALGDYLLENKFFREAVEEYIGLVKHKDDAYKVYLKMAEAYMGMQDDSNAEKILLKVLNSSRDGADLKNAHKKL
ALLYNKSKDPDLKNRAKDEAFRSAHMDPNDMEGRLVLAKILIDSNSILDREKAIDELTAIVRSDVRPKTAATAYNYLGIC
YYKNGEFKRAVRAFQSSIDLDPSLSEAYENKRAASAALEENTRREGYF

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=425, Percent_Identity=24.7058823529412, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI32307150, Length=425, Percent_Identity=24.7058823529412, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI301336134, Length=315, Percent_Identity=25.0793650793651, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI83415184, Length=315, Percent_Identity=25.0793650793651, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=425, Percent_Identity=24.7058823529412, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115532690, Length=425, Percent_Identity=24.7058823529412, Blast_Score=97, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319589, Length=336, Percent_Identity=23.2142857142857, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17647755, Length=430, Percent_Identity=23.953488372093, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24585827, Length=430, Percent_Identity=23.953488372093, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24585829, Length=430, Percent_Identity=23.953488372093, Blast_Score=94, Evalue=4e-19,
Organism=Drosophila melanogaster, GI161076610, Length=324, Percent_Identity=23.4567901234568, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19920486, Length=324, Percent_Identity=23.4567901234568, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17137540, Length=488, Percent_Identity=19.4672131147541, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR013105
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1; PF07719 TPR_2 [H]

EC number: NA

Molecular weight: Translated: 78009; Mature: 78009

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKEIRKNRLFLEGIEEEEFYFPENKEPVRIRRSYNKLLIFWILMGLLVLGGIGFAVYHQ
CCCHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFRNSSSGSEFAGAFNKDLIQNKSDINRLLERPYIPDGNANPALTKCINLYKERFTRQAF
HHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DTCNEFLDSTGTQEEKSIALTVLGVIHDESGRYPQAIERLQKAIQYDPKNFYAYYNLTLS
HHHHHHHHCCCCCCHHHEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEE
YKHAGRFADARMAALKAKEIAPSDPRVSLLAGNLFNELNDPDAAIDAYKEGLSTSPDDMH
ECCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEE
LTYNLGVSYFKKGEIPQAEEEFKKVVIKTPSGRLAALSHSYLGNIAYNKQDYKNAEYHFR
EEEECCHHHHCCCCCCCHHHHHHEEEEECCCCCEEHHHHHHHCCCCCCCCCCCCHHHHHH
QASNLSPNEAKYLYNLAIVLQKNGNKEEALKYLELARDAGANDPEIYRLIAEGFSNLNQG
HCCCCCCHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
EMSISALQKSLKYNPTDVDSLFQLAEAYYNKGDLLSAEETYRRIVSSTPGDSFTETALIN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
LGVVLDQMERYGEAVTTLNRVIELNPKNAKAYHTLGIVYKHSGNGTLAIENWRKSTAIEP
HHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEEEEECCCCEEEEECCCCCCCCCC
ENIQSREALGDYLLENKFFREAVEEYIGLVKHKDDAYKVYLKMAEAYMGMQDDSNAEKIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
LKVLNSSRDGADLKNAHKKLALLYNKSKDPDLKNRAKDEAFRSAHMDPNDMEGRLVLAKI
HHHHHCCCCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
LIDSNSILDREKAIDELTAIVRSDVRPKTAATAYNYLGICYYKNGEFKRAVRAFQSSIDL
HCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEEEEEECCHHHHHHHHHHHHCCC
DPSLSEAYENKRAASAALEENTRREGYF
CCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDKEIRKNRLFLEGIEEEEFYFPENKEPVRIRRSYNKLLIFWILMGLLVLGGIGFAVYHQ
CCCHHHHCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFRNSSSGSEFAGAFNKDLIQNKSDINRLLERPYIPDGNANPALTKCINLYKERFTRQAF
HHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DTCNEFLDSTGTQEEKSIALTVLGVIHDESGRYPQAIERLQKAIQYDPKNFYAYYNLTLS
HHHHHHHHCCCCCCHHHEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEE
YKHAGRFADARMAALKAKEIAPSDPRVSLLAGNLFNELNDPDAAIDAYKEGLSTSPDDMH
ECCCCCHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEE
LTYNLGVSYFKKGEIPQAEEEFKKVVIKTPSGRLAALSHSYLGNIAYNKQDYKNAEYHFR
EEEECCHHHHCCCCCCCHHHHHHEEEEECCCCCEEHHHHHHHCCCCCCCCCCCCHHHHHH
QASNLSPNEAKYLYNLAIVLQKNGNKEEALKYLELARDAGANDPEIYRLIAEGFSNLNQG
HCCCCCCHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
EMSISALQKSLKYNPTDVDSLFQLAEAYYNKGDLLSAEETYRRIVSSTPGDSFTETALIN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
LGVVLDQMERYGEAVTTLNRVIELNPKNAKAYHTLGIVYKHSGNGTLAIENWRKSTAIEP
HHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEEEEECCCCEEEEECCCCCCCCCC
ENIQSREALGDYLLENKFFREAVEEYIGLVKHKDDAYKVYLKMAEAYMGMQDDSNAEKIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
LKVLNSSRDGADLKNAHKKLALLYNKSKDPDLKNRAKDEAFRSAHMDPNDMEGRLVLAKI
HHHHHCCCCCCHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
LIDSNSILDREKAIDELTAIVRSDVRPKTAATAYNYLGICYYKNGEFKRAVRAFQSSIDL
HCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEEEEEEECCHHHHHHHHHHHHCCC
DPSLSEAYENKRAASAALEENTRREGYF
CCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105307 [H]