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The map label for this gene is tlyA

Identifier: 45656188

GI number: 45656188

Start: 323499

End: 324278

Strand: Direct

Name: tlyA

Synonym: LIC10284

Alternate gene names: 45656188

Gene position: 323499-324278 (Clockwise)

Preceding gene: 45656187

Following gene: 45656189

Centisome position: 7.56

GC content: 34.62

Gene sequence:

>780_bases
TTGGCCAGAGAAAAAATTAGGCTCGATGTTCTTCTTTTTGAAAGGGGATTTGCCGATTCTCTGGAAAAAGCGAAAAGTTT
AATTCTTTCGGGCTCTGTATTAGTAAACGAACAAAAGATTACTAAAGTAGGATTCAAATTTCCAAAAGATTCTGAAATCA
GAATTTTAAACATCATTCCAGAATATGTAAGCAGAGGAGTTTATAAACTGTTAAAAGCCTTTGAGGTTTTTCCTTTACAA
GTTGATGGAAAACTTTGTATAGATTTGGGTGCTTCTACGGGAGGATTTACGCAAGTGCTTTTAGAAAAAGGGGCTTGGAA
AGTTTTTGCTTGTGATGTGGGTTATGGTCAGCTTGCAGAAAAGTTAAGAAATCATTCTTCTGTGATCGTAAAAGATCGTT
TTCATCTAAAAAATTTATCTGCTTTAGAAATCGACTGGGAAAACAATCGGTTTCAAACACCTCATCCGGAAGCGATCGTA
ATCGTAATGGACTTGAGTTTTATTTCTCTCCGATCCGTTTTTCCAGTGATCCAAAAATTGAGAAAAGAAAAGGACATTCC
AAAATTAGAATGTGTTTCTTTGATAAAACCACAATTTGAAGCCAATCGGAATGACCTTGTTAAAGGTATTTTAAAAGATT
CTAAAATTCGATTTCAAATTGTACTTTCTCTTTGTAGGTATCTTAAAAAGGAAATTGGAGGTTTCGTTTTAGGTTTGGAA
TGGTCTCCGATAGAAGGTAGGGACGGAAATAAAGAAATCCTTTTGTTTTGGAGCTTATAG

Upstream 100 bases:

>100_bases
AAGATGGTAGAAGAACTTCAGAAAAATCTAATTTTTACTTCTTCTGATTTTGTTTCCACAGAAGAAGAACAAACATTCTT
TCAGGAGCTTCCGATTTACA

Downstream 100 bases:

>100_bases
AGTTAAGTCGGATTTCTACTTTGTAAATAAGTCTTATCTTTTTTAGAAAGTTCACTTTACATTTTGATTCGAAAAAATAC
AGAGTATAATTGATAGGGAC

Product: hemolysin A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MAREKIRLDVLLFERGFADSLEKAKSLILSGSVLVNEQKITKVGFKFPKDSEIRILNIIPEYVSRGVYKLLKAFEVFPLQ
VDGKLCIDLGASTGGFTQVLLEKGAWKVFACDVGYGQLAEKLRNHSSVIVKDRFHLKNLSALEIDWENNRFQTPHPEAIV
IVMDLSFISLRSVFPVIQKLRKEKDIPKLECVSLIKPQFEANRNDLVKGILKDSKIRFQIVLSLCRYLKKEIGGFVLGLE
WSPIEGRDGNKEILLFWSL

Sequences:

>Translated_259_residues
MAREKIRLDVLLFERGFADSLEKAKSLILSGSVLVNEQKITKVGFKFPKDSEIRILNIIPEYVSRGVYKLLKAFEVFPLQ
VDGKLCIDLGASTGGFTQVLLEKGAWKVFACDVGYGQLAEKLRNHSSVIVKDRFHLKNLSALEIDWENNRFQTPHPEAIV
IVMDLSFISLRSVFPVIQKLRKEKDIPKLECVSLIKPQFEANRNDLVKGILKDSKIRFQIVLSLCRYLKKEIGGFVLGLE
WSPIEGRDGNKEILLFWSL
>Mature_258_residues
AREKIRLDVLLFERGFADSLEKAKSLILSGSVLVNEQKITKVGFKFPKDSEIRILNIIPEYVSRGVYKLLKAFEVFPLQV
DGKLCIDLGASTGGFTQVLLEKGAWKVFACDVGYGQLAEKLRNHSSVIVKDRFHLKNLSALEIDWENNRFQTPHPEAIVI
VMDLSFISLRSVFPVIQKLRKEKDIPKLECVSLIKPQFEANRNDLVKGILKDSKIRFQIVLSLCRYLKKEIGGFVLGLEW
SPIEGRDGNKEILLFWSL

Specific function: Unknown

COG id: COG1189

COG function: function code J; Predicted rRNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004538
- InterPro:   IPR002877
- InterPro:   IPR002942 [H]

Pfam domain/function: PF01728 FtsJ; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 29507; Mature: 29376

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50889 S4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAREKIRLDVLLFERGFADSLEKAKSLILSGSVLVNEQKITKVGFKFPKDSEIRILNIIP
CCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCCCCEEEEEECH
EYVSRGVYKLLKAFEVFPLQVDGKLCIDLGASTGGFTQVLLEKGAWKVFACDVGYGQLAE
HHHHHHHHHHHHHHHEEEEEECCEEEEEECCCCCHHHHHHHHCCCCEEEEEECCHHHHHH
KLRNHSSVIVKDRFHLKNLSALEIDWENNRFQTPHPEAIVIVMDLSFISLRSVFPVIQKL
HHHCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHH
RKEKDIPKLECVSLIKPQFEANRNDLVKGILKDSKIRFQIVLSLCRYLKKEIGGFVLGLE
HHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEE
WSPIEGRDGNKEILLFWSL
ECCCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
AREKIRLDVLLFERGFADSLEKAKSLILSGSVLVNEQKITKVGFKFPKDSEIRILNIIP
CCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCCCCEEEEEECH
EYVSRGVYKLLKAFEVFPLQVDGKLCIDLGASTGGFTQVLLEKGAWKVFACDVGYGQLAE
HHHHHHHHHHHHHHHEEEEEECCEEEEEECCCCCHHHHHHHHCCCCEEEEEECCHHHHHH
KLRNHSSVIVKDRFHLKNLSALEIDWENNRFQTPHPEAIVIVMDLSFISLRSVFPVIQKL
HHHCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHH
RKEKDIPKLECVSLIKPQFEANRNDLVKGILKDSKIRFQIVLSLCRYLKKEIGGFVLGLE
HHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEEEE
WSPIEGRDGNKEILLFWSL
ECCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 2507400 [H]