Click here to switch to the map view.

The map label for this gene is mat [H]

Identifier: 45359203

GI number: 45359203

Start: 1582001

End: 1583218

Strand: Direct

Name: mat [H]

Synonym: MMP1640

Alternate gene names: 45359203

Gene position: 1582001-1583218 (Clockwise)

Preceding gene: 45359202

Following gene: 45359205

Centisome position: 95.24

GC content: 37.6

Gene sequence:

>1218_bases
TTGGCAAATATCGTTGTTAAAAGACTAGAAAGAACACCAATTGATGAAATTCCTGTAGAAATCGTAGAAAGGAAGGGAAT
AGGCCACCCTGACAGTATTTGCGATGGTATTGCAGAAAGTGTAAGCGTTGCATTGTGCAAAATGTACAAAGAAAAGATGG
GCGTAGTTTTACACCACAACACTGACCAGGTTGAGCTTGTTGGGGGATACGCATACCCCGAACTCGGTGGAGGATGTATG
GTAAGCCCAATTTACATCTTGCTATCAGGAAGAGCTACAATGGAAGTGTTGGACAAAGAAACTGGCAAAATTATTAAATT
GCCTGTTAATACAACCGCAGTAAATGCTGCAAGAGACTACCTGAAAAAAGCTTTAAGAAACATGGACCTTGAAAAAGACG
TTGTTGTTGACTGTAGAATTGGACAGGGTTCAGTTGATTTAGTTGAAGTATTTGATAGGAAAAGAACTGAAATTCCCCAC
GCAAACGATACTTCATTTGGTGTAGGCCACGCTCCATTAAGTACAACTGAAAAAATCGTTTTAGAAACTGAAAAATTATT
AAACAGCGATGCTTTAAAAGCAGAAATCCCTGCAGTTGGTGAAGACATCAAAGTTATGGGACTTAGAGAAGGTAAAAAAA
TCACTTTAACCATTGCTATGGCTGCTGTCGATAAATATGTAAACTCATGTGCAGATTACGTGAAAGTTAAAGAACTTGCA
AAAGCAAAAGTTGAAGAAAACGCTAAAAAATACTTAGACGGTCACGAATTAGAAGTATGCATTAACACTGCAGACGATGA
TGAAGACTGTATCTTCTTAACAGTTACTGGAACTTCCGCTGAAATGGGTGACGATGGTTCAGTAGGAAGAGGAAACAGAG
CAAACGGACTTATTACTCCATTTAGACCAATGAGTATGGAAGCTACAAGCGGTAAAAACCCAATTAACCACATTGGAAAA
ATCTACAACATCTTGTCAAACATTATTGCAGAAGATGTTGCTAAAATTGAAGGAGTAAGAGAATGTCAGATCAGGATTTT
AAGCCAGATTGGAAAACCAGTTACTGAACCAAAAATCCTCGATATCGAAATGATTCCTGAAAATGGATTTGAATTAGAAG
AATTAAGCCCTAAAGCTAAAGAAGTTGCACAAAAATGGCTCGACAATATTTCAGAAGTAACTGAAAGAATTGTAAGCGGA
AACGTAACTACATTCTAA

Upstream 100 bases:

>100_bases
TTTTTGTGTTATTTTAAAAAAGGAAGATTTAAATAATATAAATTCAATTATGCTTTTAGTATTTTTATCGAGAGTACCAT
AAATTTAAACGGTGATTTTA

Downstream 100 bases:

>100_bases
TTAAACTATTTTTTTCATTCATGTAATTTTTAACTATATCAACTATTTCTGAGATATTTTCAATTTTTATCTGTGCTGTT
TCGAGAGCTTTTTTTGATAC

Product: S-adenosylmethionine synthetase

Products: NA

Alternate protein names: AdoMet synthase; Methionine adenosyltransferase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MANIVVKRLERTPIDEIPVEIVERKGIGHPDSICDGIAESVSVALCKMYKEKMGVVLHHNTDQVELVGGYAYPELGGGCM
VSPIYILLSGRATMEVLDKETGKIIKLPVNTTAVNAARDYLKKALRNMDLEKDVVVDCRIGQGSVDLVEVFDRKRTEIPH
ANDTSFGVGHAPLSTTEKIVLETEKLLNSDALKAEIPAVGEDIKVMGLREGKKITLTIAMAAVDKYVNSCADYVKVKELA
KAKVEENAKKYLDGHELEVCINTADDDEDCIFLTVTGTSAEMGDDGSVGRGNRANGLITPFRPMSMEATSGKNPINHIGK
IYNILSNIIAEDVAKIEGVRECQIRILSQIGKPVTEPKILDIEMIPENGFELEELSPKAKEVAQKWLDNISEVTERIVSG
NVTTF

Sequences:

>Translated_405_residues
MANIVVKRLERTPIDEIPVEIVERKGIGHPDSICDGIAESVSVALCKMYKEKMGVVLHHNTDQVELVGGYAYPELGGGCM
VSPIYILLSGRATMEVLDKETGKIIKLPVNTTAVNAARDYLKKALRNMDLEKDVVVDCRIGQGSVDLVEVFDRKRTEIPH
ANDTSFGVGHAPLSTTEKIVLETEKLLNSDALKAEIPAVGEDIKVMGLREGKKITLTIAMAAVDKYVNSCADYVKVKELA
KAKVEENAKKYLDGHELEVCINTADDDEDCIFLTVTGTSAEMGDDGSVGRGNRANGLITPFRPMSMEATSGKNPINHIGK
IYNILSNIIAEDVAKIEGVRECQIRILSQIGKPVTEPKILDIEMIPENGFELEELSPKAKEVAQKWLDNISEVTERIVSG
NVTTF
>Mature_404_residues
ANIVVKRLERTPIDEIPVEIVERKGIGHPDSICDGIAESVSVALCKMYKEKMGVVLHHNTDQVELVGGYAYPELGGGCMV
SPIYILLSGRATMEVLDKETGKIIKLPVNTTAVNAARDYLKKALRNMDLEKDVVVDCRIGQGSVDLVEVFDRKRTEIPHA
NDTSFGVGHAPLSTTEKIVLETEKLLNSDALKAEIPAVGEDIKVMGLREGKKITLTIAMAAVDKYVNSCADYVKVKELAK
AKVEENAKKYLDGHELEVCINTADDDEDCIFLTVTGTSAEMGDDGSVGRGNRANGLITPFRPMSMEATSGKNPINHIGKI
YNILSNIIAEDVAKIEGVRECQIRILSQIGKPVTEPKILDIEMIPENGFELEELSPKAKEVAQKWLDNISEVTERIVSGN
VTTF

Specific function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP [H]

COG id: COG1812

COG function: function code E; Archaeal S-adenosylmethionine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AdoMet synthase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002795
- ProDom:   PD011777 [H]

Pfam domain/function: PF01941 AdoMet_Synthase [H]

EC number: =2.5.1.6 [H]

Molecular weight: Translated: 44293; Mature: 44161

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIVVKRLERTPIDEIPVEIVERKGIGHPDSICDGIAESVSVALCKMYKEKMGVVLHHN
CCCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
TDQVELVGGYAYPELGGGCMVSPIYILLSGRATMEVLDKETGKIIKLPVNTTAVNAARDY
CCEEEEEECCCCCCCCCCCHHCEEHHEECCCHHHHHHHCCCCCEEEEECCCHHHHHHHHH
LKKALRNMDLEKDVVVDCRIGQGSVDLVEVFDRKRTEIPHANDTSFGVGHAPLSTTEKIV
HHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
LETEKLLNSDALKAEIPAVGEDIKVMGLREGKKITLTIAMAAVDKYVNSCADYVKVKELA
HHHHHHHCCCCHHEECCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
KAKVEENAKKYLDGHELEVCINTADDDEDCIFLTVTGTSAEMGDDGSVGRGNRANGLITP
HHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
FRPMSMEATSGKNPINHIGKIYNILSNIIAEDVAKIEGVRECQIRILSQIGKPVTEPKIL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEE
DIEMIPENGFELEELSPKAKEVAQKWLDNISEVTERIVSGNVTTF
EEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANIVVKRLERTPIDEIPVEIVERKGIGHPDSICDGIAESVSVALCKMYKEKMGVVLHHN
CCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
TDQVELVGGYAYPELGGGCMVSPIYILLSGRATMEVLDKETGKIIKLPVNTTAVNAARDY
CCEEEEEECCCCCCCCCCCHHCEEHHEECCCHHHHHHHCCCCCEEEEECCCHHHHHHHHH
LKKALRNMDLEKDVVVDCRIGQGSVDLVEVFDRKRTEIPHANDTSFGVGHAPLSTTEKIV
HHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
LETEKLLNSDALKAEIPAVGEDIKVMGLREGKKITLTIAMAAVDKYVNSCADYVKVKELA
HHHHHHHCCCCHHEECCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
KAKVEENAKKYLDGHELEVCINTADDDEDCIFLTVTGTSAEMGDDGSVGRGNRANGLITP
HHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
FRPMSMEATSGKNPINHIGKIYNILSNIIAEDVAKIEGVRECQIRILSQIGKPVTEPKIL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEE
DIEMIPENGFELEELSPKAKEVAQKWLDNISEVTERIVSGNVTTF
EEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA