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The map label for this gene is 45359144

Identifier: 45359144

GI number: 45359144

Start: 1530899

End: 1532800

Strand: Direct

Name: 45359144

Synonym: MMP1581

Alternate gene names: NA

Gene position: 1530899-1532800 (Clockwise)

Preceding gene: 45359142

Following gene: 45359145

Centisome position: 92.16

GC content: 32.81

Gene sequence:

>1902_bases
ATGACTTTAAAGCAGATTTACGTCAATAAATTTAAGGAACTTGTTAAAAAAGAGCGCGACCACGAAATAAATTTTCATAA
AGAAGAAATTAAAAAATTGGGAACAAAGCGTGAAAACGTTGGAAGAGCCATTTTAAACTTAAACGGAAAAGTTATTAGAG
AATTCTTTGGAGAATACATTGTAAGGTATGGAAGAAGTGAAAAATTTAAGAAAACCGACATTTCTGTTGGAGATATCGTT
TTGATAAGTAAAGGAAACCCACTTCAAAGCGACCTTTTAGGAACTGTAATTGAAATTGGATCAAACCACGTGGACGTTTC
GATGGAAATCGTTCCTAAATGGGCTTTAAACGATATAAGAATCGATCTCTACGTAAATGACGTTACATTTAAAAGGATGT
TAAATGCACTTGACAAATTCAATAGTACCGATAATCGACTTATAGATATTATTTTAAGCGTAGATAGTCCACAAAAATCT
AAAACAACTGAAGTTCGCTTTTTAGACTATCGATTAAACGAATATCAAAAAGAAGCAGTTTTAGAAGCACTTGCTGCAAG
AGATTTATACCTGATACACGGGCCTCCAGGAACTGGAAAAACTAGCACCATTTCTGAAGTAATTTTACAGGAAGCTTTAC
GAAAAAACAAAGTCATTGCAACTGCTGATTCAAACATTGCAGTTGATAACATATTATCAAACATTTCAAAGCATGAATCT
TTCAAAATTGTTAGAATAGGGCACCCCTCAAGAATTTCTAAAAAATTAATAAAATATTCTTTACAAACCAAAATTACAGA
ACATCCAAACTACTCAACATTAGTAAAACTGAAAACAGAACTTCAAAAAAATTACGATTTGAGGAAAAATTTCCAAAGGC
CTGACCCAAAATGGCGAAGAGGAATGAGTAATGACGACATCATCATTTTTTCAAAATTAAATAAAGATATAAGGGGAATT
CCCAAAGAAACCATTAAACAGATGGCAGACTGGGTAATTTGCAGTGAAAATATTGCTAAAACAAAAGAAAATGTCCAAAA
ATTTGAAAAAAAGCTAATTGACGATATCATATCAACCAGCGATGTTGTTGTTGCCACAAATTCTATGGCCGGAAGCGAGA
TTTTAGAAGATTACAAATTTGATATTGCCGTGATTGATGAAGGAAGTCAGTCAACGGAACCATCTTCATTAATCCCGATC
GTAAGGTCGAGAAAATTAATTATTGCAGGAGATCACAAACAACTTCCACCAACAGTTCTCAGCGATGAATTAGAACTTAA
AAAAACACTTTTTGAAAGAATGATTCAGGAGCACCCTGAATTTTCAAAGATCCTCCAAGTTCAGTACAGGATGAATGAAA
AAATCATGGAATTTTCAAATGAAATGTTCTACGAAAATAAGCTTATCGCACACGAATCTGTAAAATCGCAAAATTTACTT
GAGATTGTAGAAAATGTTTCAAACGAAGATAAAGACATTATAAACGAAAAACCGCTTCAATTCATAAATGTTGATGGCGA
AGAAAAACAGAATTCCTTTAAATCATCATACAACGTTGAAGAAGCCGAAAAGGTATTAGAAATTGTCTCAAAACTTCAAA
AATATGAAATTCCGGTAAGTGTAATAACTCCGTACGATGCACAGGTGAAATATATTTCCAAAATGCTAAATACGGATAAA
ATAGATGTTAAATCCGTTGACGGATTTCAGGGACGCGAAAATGAAGTAATCGTGATTTCTTTTGTCCGAACCAGTAAAAT
GGGATTTTTAAAAGACCTTAAAAGATTAAACGTTGCAGTTACTCGGGCAAAGCGAAAGTTGATAGTTGTCGGTTCCAAAA
ATTTATTGATAAAGGACGATGCATACTCTAAATTTTTAAATTGTTTCAATGATAACCAGTAA

Upstream 100 bases:

>100_bases
GAATTTTTAAATTAGAATCCAAAATACTTCTGATTTTTAGGAATAATCTTAAAAATTACTACTACATATATTGCTAGTAA
CTAATAATGTTTGTGATATG

Downstream 100 bases:

>100_bases
TCAAAAGAAAAGATTGAATATTTCCCGAAATAATTAAAGAATACCGCTTTATTCCTTTTATTTTTGCGACCGAATGATTT
ATATATGATAATCTTTTATT

Product: putative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MTLKQIYVNKFKELVKKERDHEINFHKEEIKKLGTKRENVGRAILNLNGKVIREFFGEYIVRYGRSEKFKKTDISVGDIV
LISKGNPLQSDLLGTVIEIGSNHVDVSMEIVPKWALNDIRIDLYVNDVTFKRMLNALDKFNSTDNRLIDIILSVDSPQKS
KTTEVRFLDYRLNEYQKEAVLEALAARDLYLIHGPPGTGKTSTISEVILQEALRKNKVIATADSNIAVDNILSNISKHES
FKIVRIGHPSRISKKLIKYSLQTKITEHPNYSTLVKLKTELQKNYDLRKNFQRPDPKWRRGMSNDDIIIFSKLNKDIRGI
PKETIKQMADWVICSENIAKTKENVQKFEKKLIDDIISTSDVVVATNSMAGSEILEDYKFDIAVIDEGSQSTEPSSLIPI
VRSRKLIIAGDHKQLPPTVLSDELELKKTLFERMIQEHPEFSKILQVQYRMNEKIMEFSNEMFYENKLIAHESVKSQNLL
EIVENVSNEDKDIINEKPLQFINVDGEEKQNSFKSSYNVEEAEKVLEIVSKLQKYEIPVSVITPYDAQVKYISKMLNTDK
IDVKSVDGFQGRENEVIVISFVRTSKMGFLKDLKRLNVAVTRAKRKLIVVGSKNLLIKDDAYSKFLNCFNDNQ

Sequences:

>Translated_633_residues
MTLKQIYVNKFKELVKKERDHEINFHKEEIKKLGTKRENVGRAILNLNGKVIREFFGEYIVRYGRSEKFKKTDISVGDIV
LISKGNPLQSDLLGTVIEIGSNHVDVSMEIVPKWALNDIRIDLYVNDVTFKRMLNALDKFNSTDNRLIDIILSVDSPQKS
KTTEVRFLDYRLNEYQKEAVLEALAARDLYLIHGPPGTGKTSTISEVILQEALRKNKVIATADSNIAVDNILSNISKHES
FKIVRIGHPSRISKKLIKYSLQTKITEHPNYSTLVKLKTELQKNYDLRKNFQRPDPKWRRGMSNDDIIIFSKLNKDIRGI
PKETIKQMADWVICSENIAKTKENVQKFEKKLIDDIISTSDVVVATNSMAGSEILEDYKFDIAVIDEGSQSTEPSSLIPI
VRSRKLIIAGDHKQLPPTVLSDELELKKTLFERMIQEHPEFSKILQVQYRMNEKIMEFSNEMFYENKLIAHESVKSQNLL
EIVENVSNEDKDIINEKPLQFINVDGEEKQNSFKSSYNVEEAEKVLEIVSKLQKYEIPVSVITPYDAQVKYISKMLNTDK
IDVKSVDGFQGRENEVIVISFVRTSKMGFLKDLKRLNVAVTRAKRKLIVVGSKNLLIKDDAYSKFLNCFNDNQ
>Mature_632_residues
TLKQIYVNKFKELVKKERDHEINFHKEEIKKLGTKRENVGRAILNLNGKVIREFFGEYIVRYGRSEKFKKTDISVGDIVL
ISKGNPLQSDLLGTVIEIGSNHVDVSMEIVPKWALNDIRIDLYVNDVTFKRMLNALDKFNSTDNRLIDIILSVDSPQKSK
TTEVRFLDYRLNEYQKEAVLEALAARDLYLIHGPPGTGKTSTISEVILQEALRKNKVIATADSNIAVDNILSNISKHESF
KIVRIGHPSRISKKLIKYSLQTKITEHPNYSTLVKLKTELQKNYDLRKNFQRPDPKWRRGMSNDDIIIFSKLNKDIRGIP
KETIKQMADWVICSENIAKTKENVQKFEKKLIDDIISTSDVVVATNSMAGSEILEDYKFDIAVIDEGSQSTEPSSLIPIV
RSRKLIIAGDHKQLPPTVLSDELELKKTLFERMIQEHPEFSKILQVQYRMNEKIMEFSNEMFYENKLIAHESVKSQNLLE
IVENVSNEDKDIINEKPLQFINVDGEEKQNSFKSSYNVEEAEKVLEIVSKLQKYEIPVSVITPYDAQVKYISKMLNTDKI
DVKSVDGFQGRENEVIVISFVRTSKMGFLKDLKRLNVAVTRAKRKLIVVGSKNLLIKDDAYSKFLNCFNDNQ

Specific function: Unknown

COG id: COG1112

COG function: function code L; Superfamily I DNA and RNA helicases and helicase subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA2/NAM7 helicase family [H]

Homologues:

Organism=Homo sapiens, GI119392094, Length=642, Percent_Identity=30.2180685358255, Blast_Score=261, Evalue=2e-69,
Organism=Homo sapiens, GI113722133, Length=582, Percent_Identity=28.6941580756014, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI18375673, Length=301, Percent_Identity=33.5548172757475, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI254826809, Length=284, Percent_Identity=34.5070422535211, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI122937299, Length=301, Percent_Identity=34.21926910299, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI156105695, Length=524, Percent_Identity=26.7175572519084, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI156105693, Length=524, Percent_Identity=26.7175572519084, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI194272168, Length=376, Percent_Identity=29.7872340425532, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI14211540, Length=376, Percent_Identity=29.7872340425532, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI255759910, Length=289, Percent_Identity=30.4498269896194, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI14251207, Length=289, Percent_Identity=30.1038062283737, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI255759908, Length=281, Percent_Identity=30.2491103202847, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI28626521, Length=301, Percent_Identity=27.906976744186, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI54792138, Length=312, Percent_Identity=27.8846153846154, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38788372, Length=283, Percent_Identity=25.4416961130742, Blast_Score=83, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17510163, Length=590, Percent_Identity=29.1525423728814, Blast_Score=178, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI71981659, Length=504, Percent_Identity=25.9920634920635, Blast_Score=135, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17533987, Length=291, Percent_Identity=32.9896907216495, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17533985, Length=291, Percent_Identity=32.9896907216495, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17541326, Length=254, Percent_Identity=28.740157480315, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17531515, Length=534, Percent_Identity=25.2808988764045, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531513, Length=534, Percent_Identity=25.2808988764045, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17535407, Length=255, Percent_Identity=27.0588235294118, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17538027, Length=332, Percent_Identity=24.6987951807229, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71986364, Length=482, Percent_Identity=23.4439834024896, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322835, Length=709, Percent_Identity=30.0423131170663, Blast_Score=234, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6323462, Length=534, Percent_Identity=29.2134831460674, Blast_Score=174, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6323726, Length=309, Percent_Identity=35.2750809061489, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6321958, Length=300, Percent_Identity=33.6666666666667, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6321024, Length=561, Percent_Identity=28.1639928698752, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI18859757, Length=590, Percent_Identity=30.1694915254237, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24660647, Length=488, Percent_Identity=27.8688524590164, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI221330969, Length=488, Percent_Identity=27.8688524590164, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281363531, Length=491, Percent_Identity=28.5132382892057, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281363529, Length=491, Percent_Identity=28.5132382892057, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI62471854, Length=586, Percent_Identity=24.7440273037543, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24656854, Length=586, Percent_Identity=24.7440273037543, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24649577, Length=486, Percent_Identity=27.7777777777778, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI161077698, Length=358, Percent_Identity=28.4916201117318, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24640932, Length=358, Percent_Identity=28.4916201117318, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI45550425, Length=306, Percent_Identity=29.7385620915033, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI45553113, Length=316, Percent_Identity=28.1645569620253, Blast_Score=100, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR004483 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 72759; Mature: 72628

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKQIYVNKFKELVKKERDHEINFHKEEIKKLGTKRENVGRAILNLNGKVIREFFGEYI
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHCHHHHCCCHHHHHHHHHHHH
VRYGRSEKFKKTDISVGDIVLISKGNPLQSDLLGTVIEIGSNHVDVSMEIVPKWALNDIR
HHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEE
IDLYVNDVTFKRMLNALDKFNSTDNRLIDIILSVDSPQKSKTTEVRFLDYRLNEYQKEAV
EEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHH
LEALAARDLYLIHGPPGTGKTSTISEVILQEALRKNKVIATADSNIAVDNILSNISKHES
HHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCC
FKIVRIGHPSRISKKLIKYSLQTKITEHPNYSTLVKLKTELQKNYDLRKNFQRPDPKWRR
EEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCHHHHC
GMSNDDIIIFSKLNKDIRGIPKETIKQMADWVICSENIAKTKENVQKFEKKLIDDIISTS
CCCCCCEEEEECCCCHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
DVVVATNSMAGSEILEDYKFDIAVIDEGSQSTEPSSLIPIVRSRKLIIAGDHKQLPPTVL
CEEEEECCCCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCEEEEECCCCCCCCHHH
SDELELKKTLFERMIQEHPEFSKILQVQYRMNEKIMEFSNEMFYENKLIAHESVKSQNLL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHH
EIVENVSNEDKDIINEKPLQFINVDGEEKQNSFKSSYNVEEAEKVLEIVSKLQKYEIPVS
HHHHHCCCCCHHHHCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEE
VITPYDAQVKYISKMLNTDKIDVKSVDGFQGRENEVIVISFVRTSKMGFLKDLKRLNVAV
EECCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
TRAKRKLIVVGSKNLLIKDDAYSKFLNCFNDNQ
HHCCCEEEEEECCCEEEECHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLKQIYVNKFKELVKKERDHEINFHKEEIKKLGTKRENVGRAILNLNGKVIREFFGEYI
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHCHHHHCCCHHHHHHHHHHHH
VRYGRSEKFKKTDISVGDIVLISKGNPLQSDLLGTVIEIGSNHVDVSMEIVPKWALNDIR
HHHCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEE
IDLYVNDVTFKRMLNALDKFNSTDNRLIDIILSVDSPQKSKTTEVRFLDYRLNEYQKEAV
EEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHH
LEALAARDLYLIHGPPGTGKTSTISEVILQEALRKNKVIATADSNIAVDNILSNISKHES
HHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCC
FKIVRIGHPSRISKKLIKYSLQTKITEHPNYSTLVKLKTELQKNYDLRKNFQRPDPKWRR
EEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCHHHHC
GMSNDDIIIFSKLNKDIRGIPKETIKQMADWVICSENIAKTKENVQKFEKKLIDDIISTS
CCCCCCEEEEECCCCHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
DVVVATNSMAGSEILEDYKFDIAVIDEGSQSTEPSSLIPIVRSRKLIIAGDHKQLPPTVL
CEEEEECCCCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHCCEEEEECCCCCCCCHHH
SDELELKKTLFERMIQEHPEFSKILQVQYRMNEKIMEFSNEMFYENKLIAHESVKSQNLL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHH
EIVENVSNEDKDIINEKPLQFINVDGEEKQNSFKSSYNVEEAEKVLEIVSKLQKYEIPVS
HHHHHCCCCCHHHHCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEE
VITPYDAQVKYISKMLNTDKIDVKSVDGFQGRENEVIVISFVRTSKMGFLKDLKRLNVAV
EECCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHH
TRAKRKLIVVGSKNLLIKDDAYSKFLNCFNDNQ
HHCCCEEEEEECCCEEEECHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]