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The map label for this gene is pheT [H]

Identifier: 45358818

GI number: 45358818

Start: 1238051

End: 1239715

Strand: Direct

Name: pheT [H]

Synonym: MMP1255

Alternate gene names: 45358818

Gene position: 1238051-1239715 (Clockwise)

Preceding gene: 45358817

Following gene: 45358819

Centisome position: 74.53

GC content: 33.03

Gene sequence:

>1665_bases
GTGCCTACAATTAACGTGAATAAAGTAGATTTGGAACGATTGAGCAATATTTCGCTTTCGGACAAATTAATAGAAGATAG
ATTCCCAATGATGGGTGTTGAAGTAGAAGAAATATTCGAAGAAGTCGATAAAAACGGGAAAAAACAGAACATGGTGCAGT
TTTCAATAAATCCTGATAGGCCAGATTATTTAAGTGTTGAAGGCCTTGCAAGAGGTTTTAGAGGATTTATGGGAATTACT
ACAGGAATCCAAGAATTTGAAGTACTTGATTCAGACATTAAAGTAACTGTTGAAGAAAATGAAACAAGACCTTATGTTGC
ATTTGCACTTGTTAAAAATGTTTTAATGGATGAATTCGTCCTTGAAAGCATGATTAACCTTCAGGAAAAGTTGCACTGGG
CAATTGGAAGAGATAGAAAGAAACTTGCAATTGGAATTCACGACTTTGATAAAGTAAAAGCTCCATTTACTTACAAAGAA
ATCAAAGGGGATGAAATTAAATTTGTTCCTTTAGGTTATGAAGACGAAGAAATGACTCCAAGAGAAATTATTGAAAAACA
CGAAAAAGGAATAAAATACGCTCATTTAATTCAAAACGATAAATTCCCAATTATTCTCGATGCAAATGGCGAAGTTCTAT
CCCTCCCACCAATAATCAATGGAACTTTAACAAAAGTAACTCCAACATCTAAAAACTTACTTATCGACATTACTGGAACT
GAAAAGGAAGCTGTTGAAGAAACATTAAACATTATAGTCTGTGCACTTGTAGAAAGACGCGGAACCATTGTTTCAGTTAA
TGTTAACGGGAAAAAATACCCGGATTTGACTCCAAAATCAAGAATAATTTCTGTCGAATCAATTAATAAAAAATTAGGAC
TAAATTTAAATCCTGGAGAAATAATTCAGGCACTTAAAAAATCAGGAATGGATGCACTCTACGAAGATGGAAACTTAATT
GTAAAAATTCCTGCGTACAGAAATGATATCCTACAAAACGTTGATTTAAAAGAAGAAATTGCTATAAACTACGGATATGA
AAAATTCGACGGAAAATTGCCATCAGTTGCAACTACTGGCTCAAAAGATCCTGTTGAGAAAAAATGTAGTGCAATGTCTG
ATTTAATGATTGGACTTGGATTCTACGAAGTTATGAATTTAACCCTTTCAAATCAGGATACTTTGTTTGAAAAGATGAAT
TTAAAAGTAGATGAAAAAGACTACATCGAAGTTTTAAAACCTGCTTCAATCGAACACAGGGTTCTTAGAACTTCAATTTT
ACCACTTCTTTTAGAAACGCTCTACATTAACAAACACAACGCTCTTCCTCAAAAAATATTTGAAGTTGGTGACTGTGTAG
TTATCGATGAAGAAGATACTGAAACTGATACAAAGTGTAAAAATATCAAGAAAATTGCGGGTGCAATAACACATCCTTTA
ACGAACTTTAACGAAATAAAAAGCTCAACTGAAGCACTTCTAAGGGAATTTTTTGAAGGTTTTGAATTTGAAAACTATGA
ACACCCAGCATTCATACCTGGAAGATGTGCAAAAATACTTAAAAGTGGAAAAGAAGTTGGATTCTTTGGGGAAATACACC
CTGAAGTTATTTTAAACTTCGAACTCGAACATCCAGTAGTTGGATTTGAAATAACAATTGAATAA

Upstream 100 bases:

>100_bases
GAAACTAAAAAAGAAACTGTTTTAGTTGAATACAATAACAAAAAAATGATAATGGAATAATTTAGAATATACGTTTAAAT
TAAAAATATGGGTGAATACT

Downstream 100 bases:

>100_bases
CTATTTTAACTTTTTTGACATAAATTAATTTAGATCATTTTTTTAATTTCGAAAGGTGAACAATCTTGCAACTTTTTATT
TTAGATAGCGATCCACTAAA

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MPTINVNKVDLERLSNISLSDKLIEDRFPMMGVEVEEIFEEVDKNGKKQNMVQFSINPDRPDYLSVEGLARGFRGFMGIT
TGIQEFEVLDSDIKVTVEENETRPYVAFALVKNVLMDEFVLESMINLQEKLHWAIGRDRKKLAIGIHDFDKVKAPFTYKE
IKGDEIKFVPLGYEDEEMTPREIIEKHEKGIKYAHLIQNDKFPIILDANGEVLSLPPIINGTLTKVTPTSKNLLIDITGT
EKEAVEETLNIIVCALVERRGTIVSVNVNGKKYPDLTPKSRIISVESINKKLGLNLNPGEIIQALKKSGMDALYEDGNLI
VKIPAYRNDILQNVDLKEEIAINYGYEKFDGKLPSVATTGSKDPVEKKCSAMSDLMIGLGFYEVMNLTLSNQDTLFEKMN
LKVDEKDYIEVLKPASIEHRVLRTSILPLLLETLYINKHNALPQKIFEVGDCVVIDEEDTETDTKCKNIKKIAGAITHPL
TNFNEIKSSTEALLREFFEGFEFENYEHPAFIPGRCAKILKSGKEVGFFGEIHPEVILNFELEHPVVGFEITIE

Sequences:

>Translated_554_residues
MPTINVNKVDLERLSNISLSDKLIEDRFPMMGVEVEEIFEEVDKNGKKQNMVQFSINPDRPDYLSVEGLARGFRGFMGIT
TGIQEFEVLDSDIKVTVEENETRPYVAFALVKNVLMDEFVLESMINLQEKLHWAIGRDRKKLAIGIHDFDKVKAPFTYKE
IKGDEIKFVPLGYEDEEMTPREIIEKHEKGIKYAHLIQNDKFPIILDANGEVLSLPPIINGTLTKVTPTSKNLLIDITGT
EKEAVEETLNIIVCALVERRGTIVSVNVNGKKYPDLTPKSRIISVESINKKLGLNLNPGEIIQALKKSGMDALYEDGNLI
VKIPAYRNDILQNVDLKEEIAINYGYEKFDGKLPSVATTGSKDPVEKKCSAMSDLMIGLGFYEVMNLTLSNQDTLFEKMN
LKVDEKDYIEVLKPASIEHRVLRTSILPLLLETLYINKHNALPQKIFEVGDCVVIDEEDTETDTKCKNIKKIAGAITHPL
TNFNEIKSSTEALLREFFEGFEFENYEHPAFIPGRCAKILKSGKEVGFFGEIHPEVILNFELEHPVVGFEITIE
>Mature_553_residues
PTINVNKVDLERLSNISLSDKLIEDRFPMMGVEVEEIFEEVDKNGKKQNMVQFSINPDRPDYLSVEGLARGFRGFMGITT
GIQEFEVLDSDIKVTVEENETRPYVAFALVKNVLMDEFVLESMINLQEKLHWAIGRDRKKLAIGIHDFDKVKAPFTYKEI
KGDEIKFVPLGYEDEEMTPREIIEKHEKGIKYAHLIQNDKFPIILDANGEVLSLPPIINGTLTKVTPTSKNLLIDITGTE
KEAVEETLNIIVCALVERRGTIVSVNVNGKKYPDLTPKSRIISVESINKKLGLNLNPGEIIQALKKSGMDALYEDGNLIV
KIPAYRNDILQNVDLKEEIAINYGYEKFDGKLPSVATTGSKDPVEKKCSAMSDLMIGLGFYEVMNLTLSNQDTLFEKMNL
KVDEKDYIEVLKPASIEHRVLRTSILPLLLETLYINKHNALPQKIFEVGDCVVIDEEDTETDTKCKNIKKIAGAITHPLT
NFNEIKSSTEALLREFFEGFEFENYEHPAFIPGRCAKILKSGKEVGFFGEIHPEVILNFELEHPVVGFEITIE

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B5 domain [H]

Homologues:

Organism=Homo sapiens, GI124028525, Length=589, Percent_Identity=31.5789473684211, Blast_Score=273, Evalue=4e-73,
Organism=Homo sapiens, GI24308207, Length=183, Percent_Identity=27.3224043715847, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17533403, Length=600, Percent_Identity=32, Blast_Score=260, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6323089, Length=599, Percent_Identity=28.2136894824708, Blast_Score=222, Evalue=1e-58,
Organism=Drosophila melanogaster, GI21355211, Length=590, Percent_Identity=30.1694915254237, Blast_Score=276, Evalue=3e-74,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR004531
- InterPro:   IPR022918
- InterPro:   IPR002319 [H]

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 62645; Mature: 62514

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTINVNKVDLERLSNISLSDKLIEDRFPMMGVEVEEIFEEVDKNGKKQNMVQFSINPDR
CCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCC
PDYLSVEGLARGFRGFMGITTGIQEFEVLDSDIKVTVEENETRPYVAFALVKNVLMDEFV
CCEEEHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
LESMINLQEKLHWAIGRDRKKLAIGIHDFDKVKAPFTYKEIKGDEIKFVPLGYEDEEMTP
HHHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCCCEEHHHCCCCEEEEEECCCCCCCCCH
REIIEKHEKGIKYAHLIQNDKFPIILDANGEVLSLPPIINGTLTKVTPTSKNLLIDITGT
HHHHHHHHCCCEEEEHHCCCCCCEEECCCCCEEECCCCCCCCEEEECCCCCCEEEEEECC
EKEAVEETLNIIVCALVERRGTIVSVNVNGKKYPDLTPKSRIISVESINKKLGLNLNPGE
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHEEEHHHHHHHHCCCCCHHH
IIQALKKSGMDALYEDGNLIVKIPAYRNDILQNVDLKEEIAINYGYEKFDGKLPSVATTG
HHHHHHHCCCCEEECCCCEEEECCCHHHHHHHCCCCHHHHEEECCCHHHCCCCCCEECCC
SKDPVEKKCSAMSDLMIGLGFYEVMNLTLSNQDTLFEKMNLKVDEKDYIEVLKPASIEHR
CCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHCCCCCCHHHHHHHCCCCHHHH
VLRTSILPLLLETLYINKHNALPQKIFEVGDCVVIDEEDTETDTKCKNIKKIAGAITHPL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCC
TNFNEIKSSTEALLREFFEGFEFENYEHPAFIPGRCAKILKSGKEVGFFGEIHPEVILNF
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEEEE
ELEHPVVGFEITIE
EECCCEEEEEEEEC
>Mature Secondary Structure 
PTINVNKVDLERLSNISLSDKLIEDRFPMMGVEVEEIFEEVDKNGKKQNMVQFSINPDR
CCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCC
PDYLSVEGLARGFRGFMGITTGIQEFEVLDSDIKVTVEENETRPYVAFALVKNVLMDEFV
CCEEEHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHH
LESMINLQEKLHWAIGRDRKKLAIGIHDFDKVKAPFTYKEIKGDEIKFVPLGYEDEEMTP
HHHHHHHHHHHHHHHCCCCCEEEEEECCHHHCCCCEEHHHCCCCEEEEEECCCCCCCCCH
REIIEKHEKGIKYAHLIQNDKFPIILDANGEVLSLPPIINGTLTKVTPTSKNLLIDITGT
HHHHHHHHCCCEEEEHHCCCCCCEEECCCCCEEECCCCCCCCEEEECCCCCCEEEEEECC
EKEAVEETLNIIVCALVERRGTIVSVNVNGKKYPDLTPKSRIISVESINKKLGLNLNPGE
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHEEEHHHHHHHHCCCCCHHH
IIQALKKSGMDALYEDGNLIVKIPAYRNDILQNVDLKEEIAINYGYEKFDGKLPSVATTG
HHHHHHHCCCCEEECCCCEEEECCCHHHHHHHCCCCHHHHEEECCCHHHCCCCCCEECCC
SKDPVEKKCSAMSDLMIGLGFYEVMNLTLSNQDTLFEKMNLKVDEKDYIEVLKPASIEHR
CCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHCCCCCCHHHHHHHCCCCHHHH
VLRTSILPLLLETLYINKHNALPQKIFEVGDCVVIDEEDTETDTKCKNIKKIAGAITHPL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCC
TNFNEIKSSTEALLREFFEGFEFENYEHPAFIPGRCAKILKSGKEVGFFGEIHPEVILNF
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEEEE
ELEHPVVGFEITIE
EECCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA