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The map label for this gene is fwdC

Identifier: 45358812

GI number: 45358812

Start: 1232954

End: 1233772

Strand: Direct

Name: fwdC

Synonym: MMP1249

Alternate gene names: 45358812

Gene position: 1232954-1233772 (Clockwise)

Preceding gene: 45358811

Following gene: 45358813

Centisome position: 74.22

GC content: 37.36

Gene sequence:

>819_bases
ATGAATGAATTAATTCTTAATTTGAAGGGCGATGTATCAGTCCCTGTTGAAATGGACAAAATACTTCCAGAAAAAATTCA
AGAAATGAGTTTAGAAGAAATTTCTGGAATTGAATTAATACAAGGAAACAAAACTGCTAAAGTAAGCGAAATCTTTGACG
TTGAACTCAAAGAAAGTGACGTTGCAAAAGTAACAATTAACAATTGCTGTAAAAAAGTTAAAAGAATCGGCGAAAAAATG
ACTTCCGGCGAAATCGTTGTAAACGGGGATGCTGGAATGTACATCGGAGTCGAAATGAAAGGCGGAAAAATTACCGTAAA
TGGTGATGCTGAAAGCTGGGTAGGTCAAAACCTTAAAGGCGGAGAAATCATCATTAACGGAAACGCTGAAAACTACGTAG
GTTCTGCATACAGGGGCGACTGGAGAGGAATGAGCGGTGGAAAAATTACTATTACGGGTAACGCTGGATCCGAACTTGGA
GAGTACCTGAAAGGTGGAACAATTGTTATTAAAGGTAACACAAAAATAATGCCTGGAATTCACCAAAACGGCGGTATGAT
TATCATCGAAGGAGATATCGAAGGAAGAGCTGGTGGAGAAATGATGAAAGGTGCTATCGTAGTTTACGGTAAAATCTTAG
AACCGCTTCCATCATTCAAATTCGAAGGAATAGTTGAAGATCCACTCGTTAAATTATCTAAAAAAGATGCTGGAACTCAG
TTGAAAGGAACATTTATAAAATTCAGCGGAGACTACGTAAACACAAAACCAAAAGGACAGCTTTACGCAGCAATTGAAAA
CAATAAAAACTTAATCTAA

Upstream 100 bases:

>100_bases
CCCAGTTCAGGACGCTTACGCAAACAGCTGGATGCCAATAAACATTGATGCTACGGAAATACAATAAGGAAATCTTATTT
AATCTTTTTAAGGTGAAATT

Downstream 100 bases:

>100_bases
TACTTTTTTTAATTTTTGAAATTAATGCTATTTTGAATTATTTTTTATACTCCTATATGTATAGTATCAATTATAGAATA
AGGAGGACTACTATGATTTT

Product: tungsten containing formylmethanofuran dehydrogenase subunit C

Products: NA

Alternate protein names: Tungsten-containing formylmethanofuran dehydrogenase II subunit C

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MNELILNLKGDVSVPVEMDKILPEKIQEMSLEEISGIELIQGNKTAKVSEIFDVELKESDVAKVTINNCCKKVKRIGEKM
TSGEIVVNGDAGMYIGVEMKGGKITVNGDAESWVGQNLKGGEIIINGNAENYVGSAYRGDWRGMSGGKITITGNAGSELG
EYLKGGTIVIKGNTKIMPGIHQNGGMIIIEGDIEGRAGGEMMKGAIVVYGKILEPLPSFKFEGIVEDPLVKLSKKDAGTQ
LKGTFIKFSGDYVNTKPKGQLYAAIENNKNLI

Sequences:

>Translated_272_residues
MNELILNLKGDVSVPVEMDKILPEKIQEMSLEEISGIELIQGNKTAKVSEIFDVELKESDVAKVTINNCCKKVKRIGEKM
TSGEIVVNGDAGMYIGVEMKGGKITVNGDAESWVGQNLKGGEIIINGNAENYVGSAYRGDWRGMSGGKITITGNAGSELG
EYLKGGTIVIKGNTKIMPGIHQNGGMIIIEGDIEGRAGGEMMKGAIVVYGKILEPLPSFKFEGIVEDPLVKLSKKDAGTQ
LKGTFIKFSGDYVNTKPKGQLYAAIENNKNLI
>Mature_272_residues
MNELILNLKGDVSVPVEMDKILPEKIQEMSLEEISGIELIQGNKTAKVSEIFDVELKESDVAKVTINNCCKKVKRIGEKM
TSGEIVVNGDAGMYIGVEMKGGKITVNGDAESWVGQNLKGGEIIINGNAENYVGSAYRGDWRGMSGGKITITGNAGSELG
EYLKGGTIVIKGNTKIMPGIHQNGGMIIIEGDIEGRAGGEMMKGAIVVYGKILEPLPSFKFEGIVEDPLVKLSKKDAGTQ
LKGTFIKFSGDYVNTKPKGQLYAAIENNKNLI

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile

COG id: COG2218

COG function: function code C; Formylmethanofuran dehydrogenase subunit C

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fwdC/fmdC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FWDC_METMP (O31112)

Other databases:

- EMBL:   AF029842
- EMBL:   BX950229
- RefSeq:   NP_988369.1
- ProteinModelPortal:   O31112
- GeneID:   2762780
- GenomeReviews:   BX950229_GR
- KEGG:   mmp:MMP1249
- NMPDR:   fig|267377.1.peg.1249
- HOGENOM:   HBG541237
- OMA:   YVGSAYR
- ProtClustDB:   CLSK876482
- BioCyc:   MMAR267377:MMP1249-MONOMER
- BRENDA:   1.2.99.5
- GO:   GO:0015948
- InterPro:   IPR017550
- InterPro:   IPR002489
- Gene3D:   G3DSA:2.160.20.60
- TIGRFAMs:   TIGR03122

Pfam domain/function: PF01493 GXGXG; SSF69336 Glu_synthase_C

EC number: =1.2.99.5

Molecular weight: Translated: 29187; Mature: 29187

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELILNLKGDVSVPVEMDKILPEKIQEMSLEEISGIELIQGNKTAKVSEIFDVELKESD
CCCEEEEECCCEECCEEHHHHHHHHHHHCCHHHCCCEEEEECCCCEEEEEEEEEEECCCC
VAKVTINNCCKKVKRIGEKMTSGEIVVNGDAGMYIGVEMKGGKITVNGDAESWVGQNLKG
EEEEEHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEECCEEEECCCCHHHHCCCCCC
GEIIINGNAENYVGSAYRGDWRGMSGGKITITGNAGSELGEYLKGGTIVIKGNTKIMPGI
CEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCEEEEECCCEEECCE
HQNGGMIIIEGDIEGRAGGEMMKGAIVVYGKILEPLPSFKFEGIVEDPLVKLSKKDAGTQ
ECCCCEEEEECCCCCCCCCHHHCCEEEEEEEHHCCCCCCCCCCCCCCCHHHECCCCCCCE
LKGTFIKFSGDYVNTKPKGQLYAAIENNKNLI
EEEEEEEEECCEECCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MNELILNLKGDVSVPVEMDKILPEKIQEMSLEEISGIELIQGNKTAKVSEIFDVELKESD
CCCEEEEECCCEECCEEHHHHHHHHHHHCCHHHCCCEEEEECCCCEEEEEEEEEEECCCC
VAKVTINNCCKKVKRIGEKMTSGEIVVNGDAGMYIGVEMKGGKITVNGDAESWVGQNLKG
EEEEEHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEECCEEEECCCCHHHHCCCCCC
GEIIINGNAENYVGSAYRGDWRGMSGGKITITGNAGSELGEYLKGGTIVIKGNTKIMPGI
CEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCEEEEECCCEEECCE
HQNGGMIIIEGDIEGRAGGEMMKGAIVVYGKILEPLPSFKFEGIVEDPLVKLSKKDAGTQ
ECCCCEEEEECCCCCCCCCHHHCCEEEEEEEHHCCCCCCCCCCCCCCCHHHECCCCCCCE
LKGTFIKFSGDYVNTKPKGQLYAAIENNKNLI
EEEEEEEEECCEECCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA