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The map label for this gene is fwdA [H]

Identifier: 45358811

GI number: 45358811

Start: 1231217

End: 1232920

Strand: Direct

Name: fwdA [H]

Synonym: MMP1248

Alternate gene names: 45358811

Gene position: 1231217-1232920 (Clockwise)

Preceding gene: 45358810

Following gene: 45358812

Centisome position: 74.12

GC content: 39.03

Gene sequence:

>1704_bases
ATGGAATATATCATAAGAAATGGTACCGTCTTTGACCCATTAAACAATGTCAACGGAGAAAAGATGGATATCTGCGTAAA
AGACGGAAAAATCGTAGAATCTGTATCAAAAAATGCTTTAGAAATTGATGCAAATAATAAAGTAGTAATGGCAGGCGGTG
TTGATTCACACAGCCACATTGCAGGAGCTAAAGTAAATACTGGAAGGACATTAAGACCTGAAGACAGTAAAAAAGATCTA
TTTTCAAAAGAAGGATTGAGACAAGGATCAGGATTTTCAATACCTTCGACATTCAAAACAGGTTACCAATACTCAGGTAT
GGGTTACACAACAGTTATCGAAGCAGCTATGCCTCCGCTTGTTGCAAGACACACACACGAAGAATTTATGGATTTACCAC
AAATCGACAAAGCTGCAATGCCATTATTTGGTAACAGCTGGATGGTACTTGAGTACTTGAAAAACGGCGATTTAAGTATG
TGTGCCGCATACGTTGCATGGCTTTTAAGAGTAACAAAAGGATTTGCAATAAAAATCGTAAACCCTGGTGGAACAGAAGC
TTGGGGTTGGGGTAAAAACGTACACGGTTTAGATGACGAAGTTCCATACTTTGGAATTACGCCAAGAGAAATCGTAACAG
GACTTGCAAAAGTAAACGAAATGTTAGGGTTACCTCACTCCGTTCACGTGCACCCAAATAACCTTGGTCACCCCGGAAAC
TGGGAAACCACCATTGATACGATGGACTGTGTAAAAGATATCAAAGCTAAACCAAAATTCGGTGACAGGGATACCGTTTA
CTATAACACGCACCTCCAATTCCACTCATACGGTGGAACTTCATGGAAAGACTGCGTAAGTAAAGGAGTAGAAACTGCAG
ATTACGTGAACAAACACAAACACGTAATGATTGACGTTGGTCAAGTTACACTTGATGAAACTACAACAATGACTGCAGAT
GGACCAATGGAATACGATCTTCACATGACAAACGGCCTTAAATGGGCAAACTGTGATGTTGAGCTTGAAACAGGTTCAGG
TGTTGTTCCATTCATCTACTCACCAAAAGGACCAGTTTACTCTCTCCAATGGGCTATTGGTTTAGATATTTTCCTCTACA
CAAACCCCGAAAAATTGATTTTAACAACTGACCACCCTAATGCAGGACCATTCATAAGATACCCAAGAGTTATTGCTTGG
TTACTTAGCAAAGAATACAGAGATGACTGGATTCAAAATAGGGTTCACAAATGGGCTGCACAAAAAAGCCACATAACTGA
AACCGATAAAGAATACTCAATGTATGAAATTGCACAAATAACAAGAGCAAACTCATCAAAAGTACTTGGTTTAAGCGGCG
ACAGGGGCCATTTGGGCGTTGGTGCTAAAGCAGACATTTCAATATACGACATCGACCCTGAAGAAAAATCAGGTAAAAAG
ATAGAAAAAGCATTCCTCGAAGCAGCTTATGTTTTAAAGAACGGCGATATAGTTGTAAAGAACGGAAATGTTGTAAAAGA
AGTTTACGGAGATACAATCTTTGTAAATGCAGAGATAAACGAGAGTTTAGAATCAGAACTTTTAAAAGACCTCAACATGA
AGTTTAAAAAACTCTATTCCGTAAATATGGAAAACTACCCAGTTCAGGACGCTTACGCAAACAGCTGGATGCCAATAAAC
ATTGATGCTACGGAAATACAATAA

Upstream 100 bases:

>100_bases
CTTGAAGTAGAAGTTGAAAAAACTGACGAAGAAGTACTTTTAATGTCTGATTTAATGAGAAAAGCATACATTGAATAACT
GGAATATTTTGGGTGATCTC

Downstream 100 bases:

>100_bases
GGAAATCTTATTTAATCTTTTTAAGGTGAAATTATGAATGAATTAATTCTTAATTTGAAGGGCGATGTATCAGTCCCTGT
TGAAATGGACAAAATACTTC

Product: tungsten containing formylmethanofuran dehydrogenase subunit A

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MEYIIRNGTVFDPLNNVNGEKMDICVKDGKIVESVSKNALEIDANNKVVMAGGVDSHSHIAGAKVNTGRTLRPEDSKKDL
FSKEGLRQGSGFSIPSTFKTGYQYSGMGYTTVIEAAMPPLVARHTHEEFMDLPQIDKAAMPLFGNSWMVLEYLKNGDLSM
CAAYVAWLLRVTKGFAIKIVNPGGTEAWGWGKNVHGLDDEVPYFGITPREIVTGLAKVNEMLGLPHSVHVHPNNLGHPGN
WETTIDTMDCVKDIKAKPKFGDRDTVYYNTHLQFHSYGGTSWKDCVSKGVETADYVNKHKHVMIDVGQVTLDETTTMTAD
GPMEYDLHMTNGLKWANCDVELETGSGVVPFIYSPKGPVYSLQWAIGLDIFLYTNPEKLILTTDHPNAGPFIRYPRVIAW
LLSKEYRDDWIQNRVHKWAAQKSHITETDKEYSMYEIAQITRANSSKVLGLSGDRGHLGVGAKADISIYDIDPEEKSGKK
IEKAFLEAAYVLKNGDIVVKNGNVVKEVYGDTIFVNAEINESLESELLKDLNMKFKKLYSVNMENYPVQDAYANSWMPIN
IDATEIQ

Sequences:

>Translated_567_residues
MEYIIRNGTVFDPLNNVNGEKMDICVKDGKIVESVSKNALEIDANNKVVMAGGVDSHSHIAGAKVNTGRTLRPEDSKKDL
FSKEGLRQGSGFSIPSTFKTGYQYSGMGYTTVIEAAMPPLVARHTHEEFMDLPQIDKAAMPLFGNSWMVLEYLKNGDLSM
CAAYVAWLLRVTKGFAIKIVNPGGTEAWGWGKNVHGLDDEVPYFGITPREIVTGLAKVNEMLGLPHSVHVHPNNLGHPGN
WETTIDTMDCVKDIKAKPKFGDRDTVYYNTHLQFHSYGGTSWKDCVSKGVETADYVNKHKHVMIDVGQVTLDETTTMTAD
GPMEYDLHMTNGLKWANCDVELETGSGVVPFIYSPKGPVYSLQWAIGLDIFLYTNPEKLILTTDHPNAGPFIRYPRVIAW
LLSKEYRDDWIQNRVHKWAAQKSHITETDKEYSMYEIAQITRANSSKVLGLSGDRGHLGVGAKADISIYDIDPEEKSGKK
IEKAFLEAAYVLKNGDIVVKNGNVVKEVYGDTIFVNAEINESLESELLKDLNMKFKKLYSVNMENYPVQDAYANSWMPIN
IDATEIQ
>Mature_567_residues
MEYIIRNGTVFDPLNNVNGEKMDICVKDGKIVESVSKNALEIDANNKVVMAGGVDSHSHIAGAKVNTGRTLRPEDSKKDL
FSKEGLRQGSGFSIPSTFKTGYQYSGMGYTTVIEAAMPPLVARHTHEEFMDLPQIDKAAMPLFGNSWMVLEYLKNGDLSM
CAAYVAWLLRVTKGFAIKIVNPGGTEAWGWGKNVHGLDDEVPYFGITPREIVTGLAKVNEMLGLPHSVHVHPNNLGHPGN
WETTIDTMDCVKDIKAKPKFGDRDTVYYNTHLQFHSYGGTSWKDCVSKGVETADYVNKHKHVMIDVGQVTLDETTTMTAD
GPMEYDLHMTNGLKWANCDVELETGSGVVPFIYSPKGPVYSLQWAIGLDIFLYTNPEKLILTTDHPNAGPFIRYPRVIAW
LLSKEYRDDWIQNRVHKWAAQKSHITETDKEYSMYEIAQITRANSSKVLGLSGDRGHLGVGAKADISIYDIDPEEKSGKK
IEKAFLEAAYVLKNGDIVVKNGNVVKEVYGDTIFVNAEINESLESELLKDLNMKFKKLYSVNMENYPVQDAYANSWMPIN
IDATEIQ

Specific function: Unknown

COG id: COG1229

COG function: function code C; Formylmethanofuran dehydrogenase subunit A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR012027
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: 1.2.99.5

Molecular weight: Translated: 63266; Mature: 63266

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYIIRNGTVFDPLNNVNGEKMDICVKDGKIVESVSKNALEIDANNKVVMAGGVDSHSHI
CCEEEECCEEECCCCCCCCCEEEEEEECCHHHHHHCCCEEEEECCCEEEEECCCCCCCCC
AGAKVNTGRTLRPEDSKKDLFSKEGLRQGSGFSIPSTFKTGYQYSGMGYTTVIEAAMPPL
CCCEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCEEECCCCHHHHHHHHCCCH
VARHTHEEFMDLPQIDKAAMPLFGNSWMVLEYLKNGDLSMCAAYVAWLLRVTKGFAIKIV
HHHCCHHHHHCCCCCCHHHCCCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHCCCCEEEEE
NPGGTEAWGWGKNVHGLDDEVPYFGITPREIVTGLAKVNEMLGLPHSVHVHPNNLGHPGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
WETTIDTMDCVKDIKAKPKFGDRDTVYYNTHLQFHSYGGTSWKDCVSKGVETADYVNKHK
CCEEHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHCCCHHHHHCCCC
HVMIDVGQVTLDETTTMTADGPMEYDLHMTNGLKWANCDVELETGSGVVPFIYSPKGPVY
EEEEEECEEEECCCEEEECCCCEEEEEEECCCCEEECCEEEEECCCCEEEEEECCCCCEE
SLQWAIGLDIFLYTNPEKLILTTDHPNAGPFIRYPRVIAWLLSKEYRDDWIQNRVHKWAA
EEEEEEEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKSHITETDKEYSMYEIAQITRANSSKVLGLSGDRGHLGVGAKADISIYDIDPEEKSGKK
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCHH
IEKAFLEAAYVLKNGDIVVKNGNVVKEVYGDTIFVNAEINESLESELLKDLNMKFKKLYS
HHHHHHHHHEEEECCCEEEECCCEEHHHCCCEEEEEECCCHHHHHHHHHHHCHHHHHHEE
VNMENYPVQDAYANSWMPINIDATEIQ
CCCCCCCCCHHHCCCEEEEECCHHCCC
>Mature Secondary Structure
MEYIIRNGTVFDPLNNVNGEKMDICVKDGKIVESVSKNALEIDANNKVVMAGGVDSHSHI
CCEEEECCEEECCCCCCCCCEEEEEEECCHHHHHHCCCEEEEECCCEEEEECCCCCCCCC
AGAKVNTGRTLRPEDSKKDLFSKEGLRQGSGFSIPSTFKTGYQYSGMGYTTVIEAAMPPL
CCCEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHCCEEECCCCHHHHHHHHCCCH
VARHTHEEFMDLPQIDKAAMPLFGNSWMVLEYLKNGDLSMCAAYVAWLLRVTKGFAIKIV
HHHCCHHHHHCCCCCCHHHCCCCCCCEEEEEEHHCCCHHHHHHHHHHHHHHCCCCEEEEE
NPGGTEAWGWGKNVHGLDDEVPYFGITPREIVTGLAKVNEMLGLPHSVHVHPNNLGHPGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCC
WETTIDTMDCVKDIKAKPKFGDRDTVYYNTHLQFHSYGGTSWKDCVSKGVETADYVNKHK
CCEEHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHCCCHHHHHCCCC
HVMIDVGQVTLDETTTMTADGPMEYDLHMTNGLKWANCDVELETGSGVVPFIYSPKGPVY
EEEEEECEEEECCCEEEECCCCEEEEEEECCCCEEECCEEEEECCCCEEEEEECCCCCEE
SLQWAIGLDIFLYTNPEKLILTTDHPNAGPFIRYPRVIAWLLSKEYRDDWIQNRVHKWAA
EEEEEEEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKSHITETDKEYSMYEIAQITRANSSKVLGLSGDRGHLGVGAKADISIYDIDPEEKSGKK
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCHH
IEKAFLEAAYVLKNGDIVVKNGNVVKEVYGDTIFVNAEINESLESELLKDLNMKFKKLYS
HHHHHHHHHEEEECCCEEEECCCEEHHHCCCEEEEEECCCHHHHHHHHHHHCHHHHHHEE
VNMENYPVQDAYANSWMPINIDATEIQ
CCCCCCCCCHHHCCCEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]