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The map label for this gene is yxeM [H]

Identifier: 45358787

GI number: 45358787

Start: 1213682

End: 1214446

Strand: Direct

Name: yxeM [H]

Synonym: MMP1224

Alternate gene names: 45358787

Gene position: 1213682-1214446 (Clockwise)

Preceding gene: 45358785

Following gene: 45358788

Centisome position: 73.06

GC content: 35.42

Gene sequence:

>765_bases
GTGAAAATCCCCACAATCCTCGTAATAATCTCATCAATATTAATACTAACTTCTTTTTCAGGATGTACCTCTTCTTATGG
TAAGGAATACAATACTGTAAATCCTGGCGTATTAACAGTTGGAATTACGCCAGAAATGCCGCCACAACAATATTATGAAG
ATGGTGAACTGAAAGGCTTTGATATCGATTTGATGAAAGAAATTGCAAACAATATGGGCTTAAAACCCGAATTCAAAATT
TACGAATATGGCGGTGCACACGAAGCACTTCTAAACGGAGAAATCGATTGTCTCCCCTCGATGACGATTTCGCCAGAACG
AAAAGAAGACATGGATTTTTCAAGAGCGTACATCCAAACATACGTGGTTGTTGCAGTTTTTGAAAACAGTCCTTATCGTG
AACTTAAGGATCTAAACGGTAAAAATATTGCAGTTGTGACAAACACGTATACTGAAGATTGGGCCAAAGAATATTTGGGA
AGTCTCAACGCAAATATCAAATCCTATGATTCTGTTGAAGGATTAGTTTCAGACGTATACTCGGGAAATATTGATGCGGT
AGTTACTGATCAGATCCAGCTGGATTACTATTCAAAACAGAATAATTTTGAATCCAGATTGATTTTCGAAAAAATGACAA
TTGAATACTGGGCAATTGCAGTCAAAAAAGATAATCACAATCTCCAAAATGAAATAAACGATGTATTGTTTGAATTGGAT
GAGAATAAAGCACTCTACGAATTAAAAAATAAATGGTACGATTAA

Upstream 100 bases:

>100_bases
TAATTAATATTCATGAAATAAGACCAAATCATATGTAAAAGTTAATATATCTTTAAAGTAAAGAATATTAGTATCTGTTA
TCAACCATAAAGGAGATAAT

Downstream 100 bases:

>100_bases
TTACCATTATCCAATTACTTTTTTATTCAACTAAATTTTCAGTTATTTTTATTTAAAAAATATTAAATACCCCCTCATAA
AAACTATAATGTATGAAATA

Product: ABC-type amino acid transport/signal transduction systems periplasmic component-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKIPTILVIISSILILTSFSGCTSSYGKEYNTVNPGVLTVGITPEMPPQQYYEDGELKGFDIDLMKEIANNMGLKPEFKI
YEYGGAHEALLNGEIDCLPSMTISPERKEDMDFSRAYIQTYVVVAVFENSPYRELKDLNGKNIAVVTNTYTEDWAKEYLG
SLNANIKSYDSVEGLVSDVYSGNIDAVVTDQIQLDYYSKQNNFESRLIFEKMTIEYWAIAVKKDNHNLQNEINDVLFELD
ENKALYELKNKWYD

Sequences:

>Translated_254_residues
MKIPTILVIISSILILTSFSGCTSSYGKEYNTVNPGVLTVGITPEMPPQQYYEDGELKGFDIDLMKEIANNMGLKPEFKI
YEYGGAHEALLNGEIDCLPSMTISPERKEDMDFSRAYIQTYVVVAVFENSPYRELKDLNGKNIAVVTNTYTEDWAKEYLG
SLNANIKSYDSVEGLVSDVYSGNIDAVVTDQIQLDYYSKQNNFESRLIFEKMTIEYWAIAVKKDNHNLQNEINDVLFELD
ENKALYELKNKWYD
>Mature_254_residues
MKIPTILVIISSILILTSFSGCTSSYGKEYNTVNPGVLTVGITPEMPPQQYYEDGELKGFDIDLMKEIANNMGLKPEFKI
YEYGGAHEALLNGEIDCLPSMTISPERKEDMDFSRAYIQTYVVVAVFENSPYRELKDLNGKNIAVVTNTYTEDWAKEYLG
SLNANIKSYDSVEGLVSDVYSGNIDAVVTDQIQLDYYSKQNNFESRLIFEKMTIEYWAIAVKKDNHNLQNEINDVLFELD
ENKALYELKNKWYD

Specific function: Probably part of the ABC transporter complex yxeMNO that could be involved in amino-acid import. May transport S- methylcysteine [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=223, Percent_Identity=27.3542600896861, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787031, Length=219, Percent_Identity=27.3972602739726, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787085, Length=225, Percent_Identity=26.2222222222222, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788649, Length=259, Percent_Identity=23.5521235521236, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788648, Length=234, Percent_Identity=23.0769230769231, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 28999; Mature: 28999

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPTILVIISSILILTSFSGCTSSYGKEYNTVNPGVLTVGITPEMPPQQYYEDGELKGF
CCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCC
DIDLMKEIANNMGLKPEFKIYEYGGAHEALLNGEIDCLPSMTISPERKEDMDFSRAYIQT
CHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHH
YVVVAVFENSPYRELKDLNGKNIAVVTNTYTEDWAKEYLGSLNANIKSYDSVEGLVSDVY
EEEEEEECCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SGNIDAVVTDQIQLDYYSKQNNFESRLIFEKMTIEYWAIAVKKDNHNLQNEINDVLFELD
CCCCCEEEECEEEEEEECCCCCCHHHHHHHHHEEEEEEEEEEECCCCHHHHHHHHHHHCC
ENKALYELKNKWYD
CCCHHHHHHHHCCC
>Mature Secondary Structure
MKIPTILVIISSILILTSFSGCTSSYGKEYNTVNPGVLTVGITPEMPPQQYYEDGELKGF
CCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCC
DIDLMKEIANNMGLKPEFKIYEYGGAHEALLNGEIDCLPSMTISPERKEDMDFSRAYIQT
CHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHHH
YVVVAVFENSPYRELKDLNGKNIAVVTNTYTEDWAKEYLGSLNANIKSYDSVEGLVSDVY
EEEEEEECCCCHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SGNIDAVVTDQIQLDYYSKQNNFESRLIFEKMTIEYWAIAVKKDNHNLQNEINDVLFELD
CCCCCEEEECEEEEEEECCCCCCHHHHHHHHHEEEEEEEEEEECCCCHHHHHHHHHHHCC
ENKALYELKNKWYD
CCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8867804; 9384377 [H]