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The map label for this gene is radA [H]

Identifier: 45358785

GI number: 45358785

Start: 1210853

End: 1211821

Strand: Direct

Name: radA [H]

Synonym: MMP1222

Alternate gene names: 45358785

Gene position: 1210853-1211821 (Clockwise)

Preceding gene: 45358776

Following gene: 45358787

Centisome position: 72.89

GC content: 38.49

Gene sequence:

>969_bases
ATGGCTGACGTTTTGACCGAATTGCCTGGGGTAGGCCCATCAACTGCAGATAAATTAATTGAAGGAGGATACCTCGATTT
TATGAAAATTGCAACAGCAACTATCGGTGAATTAACTGATATTGAAGGTATCAGTGAAAAAGCTGCTGCTAAAATGATCA
TGGCTGCAAGAGATTTATGCGACCTTGGGTTCAAAAGTGGTGTTGAATTATTAAAACAAAGACAGAGTGTGTGGAGACTT
TCAACTGGAAGCACTGAATTAGATACAGTTCTTGCAGGAGGAATCGAAAGCCAGTCTGTAACGGAATTTGCAGGTATGTT
TGGAAGTGGTAAAACGCAAATTATGCATCAAACTTGCGTAAATTTACAGATCCGAGAAAAAATATTTGCAGATTTAGAAG
GAGTAGTTGAAGAAGAACTTGAAGCTCCAAAAGCAGTTTATATCGATACAGAAGGTACATTCAGACCTGAAAGAGTTGTT
CAAATGGCTGAAGGGGCTGGAATCGATGGTCAGACTGTTTTAGACAACACCTTCGTTGCTAGAGCATACAATTCAGATAT
GCAGATGTTGTTTGCTGAAAAAATTGAAGATCTGATCAAAGGCGGAAATAACATTAAATTAGTAATTATTGACTCCCTTA
CAAGCACTTTCAGAAATGAATTTACAGGAAGAGGTAAATTGGCTGAAAGACAGCAAAAATTAGGTAGGCACATGGCTACA
CTAAACAAACTTGCAGATTTATACAACTGCATTGTGTTGGTTACAAACCAGGTTGCTGCAAAACCAGATGCATACTTTGG
TGTTGCTGAACAGGCAATTGGTGGACACGTTGTGGGCCACGCTGCAACATTTAGATTCTTCTTAAGAAAATCAAAAGGAG
ATAAAAGAGTTGCAAAATTATACGACTCTCCACACCTGCCAGACTCAGAAGCAGTCTTTAGAATTACAGAAAAAGGTATT
CAAGATTAA

Upstream 100 bases:

>100_bases
TTGGCTACTTATACATTAGCTTAATTTTTAAATATTAACAATCACGGTATTTTTATACACATATTACTATTCTCATCATA
TCTAACAAAAAGGTGAAGTT

Downstream 100 bases:

>100_bases
TATCTTTTAAAAATTAAAAATAAATTTTAATATTTTCTTTTTTCATTAAAATTAAAAAAATAGAAATTTTTGAGTATTTT
AGTTATTTTAAATTATTTTA

Product: DNA repair and recombination protein RadA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MADVLTELPGVGPSTADKLIEGGYLDFMKIATATIGELTDIEGISEKAAAKMIMAARDLCDLGFKSGVELLKQRQSVWRL
STGSTELDTVLAGGIESQSVTEFAGMFGSGKTQIMHQTCVNLQIREKIFADLEGVVEEELEAPKAVYIDTEGTFRPERVV
QMAEGAGIDGQTVLDNTFVARAYNSDMQMLFAEKIEDLIKGGNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMAT
LNKLADLYNCIVLVTNQVAAKPDAYFGVAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKLYDSPHLPDSEAVFRITEKGI
QD

Sequences:

>Translated_322_residues
MADVLTELPGVGPSTADKLIEGGYLDFMKIATATIGELTDIEGISEKAAAKMIMAARDLCDLGFKSGVELLKQRQSVWRL
STGSTELDTVLAGGIESQSVTEFAGMFGSGKTQIMHQTCVNLQIREKIFADLEGVVEEELEAPKAVYIDTEGTFRPERVV
QMAEGAGIDGQTVLDNTFVARAYNSDMQMLFAEKIEDLIKGGNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMAT
LNKLADLYNCIVLVTNQVAAKPDAYFGVAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKLYDSPHLPDSEAVFRITEKGI
QD
>Mature_321_residues
ADVLTELPGVGPSTADKLIEGGYLDFMKIATATIGELTDIEGISEKAAAKMIMAARDLCDLGFKSGVELLKQRQSVWRLS
TGSTELDTVLAGGIESQSVTEFAGMFGSGKTQIMHQTCVNLQIREKIFADLEGVVEEELEAPKAVYIDTEGTFRPERVVQ
MAEGAGIDGQTVLDNTFVARAYNSDMQMLFAEKIEDLIKGGNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMATL
NKLADLYNCIVLVTNQVAAKPDAYFGVAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKLYDSPHLPDSEAVFRITEKGIQ
D

Specific function: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules [H]

COG id: COG0468

COG function: function code L; RecA/RadA recombinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic recA-like protein family [H]

Homologues:

Organism=Homo sapiens, GI19924133, Length=319, Percent_Identity=39.8119122257053, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI23238219, Length=322, Percent_Identity=40.0621118012422, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI256017143, Length=320, Percent_Identity=37.8125, Blast_Score=197, Evalue=9e-51,
Organism=Homo sapiens, GI256017141, Length=320, Percent_Identity=37.8125, Blast_Score=197, Evalue=9e-51,
Organism=Homo sapiens, GI256017145, Length=240, Percent_Identity=38.75, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI17402896, Length=354, Percent_Identity=27.1186440677966, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI46255039, Length=348, Percent_Identity=26.7241379310345, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI19924117, Length=348, Percent_Identity=26.7241379310345, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI10835029, Length=348, Percent_Identity=26.7241379310345, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI153946430, Length=269, Percent_Identity=27.1375464684015, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4885659, Length=269, Percent_Identity=27.1375464684015, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI153946427, Length=269, Percent_Identity=27.1375464684015, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71997301, Length=314, Percent_Identity=41.0828025477707, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI71997295, Length=314, Percent_Identity=41.0828025477707, Blast_Score=231, Evalue=4e-61,
Organism=Saccharomyces cerevisiae, GI6321027, Length=317, Percent_Identity=42.9022082018927, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6320942, Length=319, Percent_Identity=37.6175548589342, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320207, Length=204, Percent_Identity=29.9019607843137, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17864108, Length=295, Percent_Identity=40, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24651285, Length=284, Percent_Identity=40.1408450704225, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17136506, Length=291, Percent_Identity=29.2096219931272, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013632
- InterPro:   IPR011938
- InterPro:   IPR016467
- InterPro:   IPR020588
- InterPro:   IPR010995
- InterPro:   IPR003583
- InterPro:   IPR020587 [H]

Pfam domain/function: PF08423 Rad51 [H]

EC number: 3.6.1.-

Molecular weight: Translated: 35147; Mature: 35015

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50162 RECA_2 ; PS50163 RECA_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVLTELPGVGPSTADKLIEGGYLDFMKIATATIGELTDIEGISEKAAAKMIMAARDLC
CCCHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
DLGFKSGVELLKQRQSVWRLSTGSTELDTVLAGGIESQSVTEFAGMFGSGKTQIMHQTCV
HCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHH
NLQIREKIFADLEGVVEEELEAPKAVYIDTEGTFRPERVVQMAEGAGIDGQTVLDNTFVA
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCHHCCHHHH
RAYNSDMQMLFAEKIEDLIKGGNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMAT
HHHCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LNKLADLYNCIVLVTNQVAAKPDAYFGVAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
YDSPHLPDSEAVFRITEKGIQD
HCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
ADVLTELPGVGPSTADKLIEGGYLDFMKIATATIGELTDIEGISEKAAAKMIMAARDLC
CCHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
DLGFKSGVELLKQRQSVWRLSTGSTELDTVLAGGIESQSVTEFAGMFGSGKTQIMHQTCV
HCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHH
NLQIREKIFADLEGVVEEELEAPKAVYIDTEGTFRPERVVQMAEGAGIDGQTVLDNTFVA
CHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCHHCCHHHH
RAYNSDMQMLFAEKIEDLIKGGNNIKLVIIDSLTSTFRNEFTGRGKLAERQQKLGRHMAT
HHHCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LNKLADLYNCIVLVTNQVAAKPDAYFGVAEQAIGGHVVGHAATFRFFLRKSKGDKRVAKL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHH
YDSPHLPDSEAVFRITEKGIQD
HCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA