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The map label for this gene is tadA [H]

Identifier: 45358432

GI number: 45358432

Start: 861171

End: 861596

Strand: Direct

Name: tadA [H]

Synonym: MMP0869

Alternate gene names: 45358432

Gene position: 861171-861596 (Clockwise)

Preceding gene: 45358427

Following gene: 45358433

Centisome position: 51.84

GC content: 34.27

Gene sequence:

>426_bases
ATGGATGAAGCAGTAAAAGAAGCTAATTTAAGTCTTAAAGAGGGTGGAATTCCGATTGGCGCAGTTTTAGTTTACGAAAA
TAAGATTATCGGTCGCGGACACAACCGAAGAGTTCAAAACAACAGCGCAATACTACATGCTGAAATGGATGCGCTTGAAA
ATGCAGGACGGTTAACTTCTGACGTTTATAAAAATTGTGAACTTTATACAACCCTTTCCCCATGCATAATGTGCAGTGGT
GCAGTTTTGCTTTATAAAATTAAAAAAGTAGTAATTGGGGAAAATAAAACTTTTTTAGGTGCAGAAGATCTTTTAATAAA
AAACGGGGTTGCTGTTGAAGTTTTAAATGATGAAAGATGCGTAAAAATGATGAAAGAATTTATAGAAAATAATCCAAAAT
TGTGGAATGAAGACATCGGAGAATAA

Upstream 100 bases:

>100_bases
TCTTTTCAGAAATTATATATATTGTTTTTAAAAGAATTTACTTAACTTAAATGAATTTATTTAATTATCTGGGATTAATG
GTGAAAATGTGACTGATTTT

Downstream 100 bases:

>100_bases
TTTAAAATAGTTTTAAAAAATGTGATATTTCATGAAAATCGTTGTACTTGATGGATACGCCATGAATTCAGGAGATTTAT
CGTGGGAAGATTTAAAAAAA

Product: cytidine/deoxycytidylate deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MDEAVKEANLSLKEGGIPIGAVLVYENKIIGRGHNRRVQNNSAILHAEMDALENAGRLTSDVYKNCELYTTLSPCIMCSG
AVLLYKIKKVVIGENKTFLGAEDLLIKNGVAVEVLNDERCVKMMKEFIENNPKLWNEDIGE

Sequences:

>Translated_141_residues
MDEAVKEANLSLKEGGIPIGAVLVYENKIIGRGHNRRVQNNSAILHAEMDALENAGRLTSDVYKNCELYTTLSPCIMCSG
AVLLYKIKKVVIGENKTFLGAEDLLIKNGVAVEVLNDERCVKMMKEFIENNPKLWNEDIGE
>Mature_141_residues
MDEAVKEANLSLKEGGIPIGAVLVYENKIIGRGHNRRVQNNSAILHAEMDALENAGRLTSDVYKNCELYTTLSPCIMCSG
AVLLYKIKKVVIGENKTFLGAEDLLIKNGVAVEVLNDERCVKMMKEFIENNPKLWNEDIGE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=113, Percent_Identity=37.1681415929204, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI145693172, Length=141, Percent_Identity=34.0425531914894, Blast_Score=77, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17541138, Length=145, Percent_Identity=36.551724137931, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17554608, Length=95, Percent_Identity=35.7894736842105, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6325319, Length=144, Percent_Identity=52.0833333333333, Blast_Score=151, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15653; Mature: 15653

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEAVKEANLSLKEGGIPIGAVLVYENKIIGRGHNRRVQNNSAILHAEMDALENAGRLTS
CCCHHHHCCCEECCCCCCEEEEEEEECEEECCCCCCEECCCCEEEEEHHHHHHCCCCHHH
DVYKNCELYTTLSPCIMCSGAVLLYKIKKVVIGENKTFLGAEDLLIKNGVAVEVLNDERC
HHHCCCEEEEEHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCHHEEECCCEEEEECCHHH
VKMMKEFIENNPKLWNEDIGE
HHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDEAVKEANLSLKEGGIPIGAVLVYENKIIGRGHNRRVQNNSAILHAEMDALENAGRLTS
CCCHHHHCCCEECCCCCCEEEEEEEECEEECCCCCCEECCCCEEEEEHHHHHHCCCCHHH
DVYKNCELYTTLSPCIMCSGAVLLYKIKKVVIGENKTFLGAEDLLIKNGVAVEVLNDERC
HHHCCCEEEEEHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCHHEEECCCEEEEECCHHH
VKMMKEFIENNPKLWNEDIGE
HHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]