Click here to switch to the map view.

The map label for this gene is mcrC [C]

Identifier: 45358319

GI number: 45358319

Start: 748258

End: 749538

Strand: Direct

Name: mcrC [C]

Synonym: MMP0756

Alternate gene names: 45358319

Gene position: 748258-749538 (Clockwise)

Preceding gene: 45358318

Following gene: 45358324

Centisome position: 45.04

GC content: 25.92

Gene sequence:

>1281_bases
ATGAACAATTTAAAAGATATAACTCTAAATGAGTTTCAATACCTCATAAAAGGGCTTAATGACGAACCTCATGATCGAGG
TTTTGTGATTAATAAACATATCTTTGAAAAGTTAGAGTTATTCGTTTTGAAAAGTAAAGAAAATTCTGGCTGCGAGTTTT
TAAGGCTTACTTCACTAAATGGTAGAAAAGCACTTCAAGCGTTAAATTATGTGGGGATTATAAAATTAAAAAATGGTCCA
ACTATCGAAATACTTCCAAAAATAAATAATGACCATATTTCAAATGAAAAAGTTAGAAGAATATTTCTAAAAATGTTAAA
AAGTCTTAAAAACGCGCCTTTTAAAGAGTTTGGGGACGCAAGTCTAAAAACTCACAAAATGAAACTAAATGAAATTTTTA
TTAAAATATTTTTGGATGATTTGGATGTATTGGTCAAAAACGGATTAAAATCTGATTATATATCTATTGAAGATAATTTA
AACGTTTTAAAAGGAAAAATAAAATTTAATGAACATATATCTAAAAATTATATTCATAAAGAACGTTTTTATGTAAATTA
TGATGAATTTATTAGAAATAGGCCTGAAAATCGTATCATTAAATCTACAATCAAATATTTATTAAAAAATTCTAGCTTAA
ACTCTAATTTAAAGCGAATAAATGAATTTTTATTTATAATGGATGCAATTCCTGAATCTAAAAATTTAGAAAAAGATTTT
GCTGCATGTGTAAATAACAGGTTGATGACGGATTATAAAAAAATAATTCCTTGGTGTAAGGTTTTCTTAAAAAATGAAAG
TTTTACGAACTTTAAAGGCGACGAAATCGCGTATGCATTACTTTACCCCATGGAAAAGATTTTTGAAAGTTATCTAACTG
AAGAATTCAAAAAATCAGGAAAATTTGAAACAATAGTTTCACAGGGAAATGGTTATTTTTTAGCAAAACACAAAAATGAA
GGAATATTTCGGCTTAAACCGGATATTTATGCAGAAACCAGTTCTAAAAAGTATATAATGGATGCCAAATGGAAAATTCT
AAACTCTGATAAAAATAAAAATTATGGAATATCTCAAAATGATATGTATCAGCTTTTATCTTACGCAGTAGTCTATGGAT
GTAATGAATTGAGGCTTTTATATCCAAAAAGTAAAGATTTCAAAAGGATTTTGGAGTTTGAATACAATAATTCTATAAAC
TACAAAGAAAAAATAAGTTTAAAGATTATTCCAATCGATTTAGAACGAAATATTGCAGATCAAATTGGATTTTTACTTTA
A

Upstream 100 bases:

>100_bases
GGATATTTTATCAATCCACGATTAAAAGATGGAGAAATGCATCCAAATGCATTTATTAAGATATATAATTCCAAGGTAAA
CGAATCTTTGGAGTACTAAA

Downstream 100 bases:

>100_bases
TGTTTTATGTTATATTATCTGAAATAAACTATTCAACAATATCCAAAATAACTCTTTCAGAAAACCCGCCACGTTCATTT
AACTTTTTTATTCTTTCTTC

Product: hypothetical protein

Products: NA

Alternate protein names: 5-Methylcytosine Restriction System Component-Like Protein; 5-Methylcytosine Restriction System Component; McrBC 5-Methylcytosine Restriction System Component-Like; McrBC Catalytic Subunit McrC; McrBC Restriction Endonuclease System Subunit McrC; 5-Methylcytosine-Specific Restriction Protein C; McrBC 5-Methylcytosine Restriction Subunit McrC; 5-Methylcytosine Restriction System Component- Like Protein

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MNNLKDITLNEFQYLIKGLNDEPHDRGFVINKHIFEKLELFVLKSKENSGCEFLRLTSLNGRKALQALNYVGIIKLKNGP
TIEILPKINNDHISNEKVRRIFLKMLKSLKNAPFKEFGDASLKTHKMKLNEIFIKIFLDDLDVLVKNGLKSDYISIEDNL
NVLKGKIKFNEHISKNYIHKERFYVNYDEFIRNRPENRIIKSTIKYLLKNSSLNSNLKRINEFLFIMDAIPESKNLEKDF
AACVNNRLMTDYKKIIPWCKVFLKNESFTNFKGDEIAYALLYPMEKIFESYLTEEFKKSGKFETIVSQGNGYFLAKHKNE
GIFRLKPDIYAETSSKKYIMDAKWKILNSDKNKNYGISQNDMYQLLSYAVVYGCNELRLLYPKSKDFKRILEFEYNNSIN
YKEKISLKIIPIDLERNIADQIGFLL

Sequences:

>Translated_426_residues
MNNLKDITLNEFQYLIKGLNDEPHDRGFVINKHIFEKLELFVLKSKENSGCEFLRLTSLNGRKALQALNYVGIIKLKNGP
TIEILPKINNDHISNEKVRRIFLKMLKSLKNAPFKEFGDASLKTHKMKLNEIFIKIFLDDLDVLVKNGLKSDYISIEDNL
NVLKGKIKFNEHISKNYIHKERFYVNYDEFIRNRPENRIIKSTIKYLLKNSSLNSNLKRINEFLFIMDAIPESKNLEKDF
AACVNNRLMTDYKKIIPWCKVFLKNESFTNFKGDEIAYALLYPMEKIFESYLTEEFKKSGKFETIVSQGNGYFLAKHKNE
GIFRLKPDIYAETSSKKYIMDAKWKILNSDKNKNYGISQNDMYQLLSYAVVYGCNELRLLYPKSKDFKRILEFEYNNSIN
YKEKISLKIIPIDLERNIADQIGFLL
>Mature_426_residues
MNNLKDITLNEFQYLIKGLNDEPHDRGFVINKHIFEKLELFVLKSKENSGCEFLRLTSLNGRKALQALNYVGIIKLKNGP
TIEILPKINNDHISNEKVRRIFLKMLKSLKNAPFKEFGDASLKTHKMKLNEIFIKIFLDDLDVLVKNGLKSDYISIEDNL
NVLKGKIKFNEHISKNYIHKERFYVNYDEFIRNRPENRIIKSTIKYLLKNSSLNSNLKRINEFLFIMDAIPESKNLEKDF
AACVNNRLMTDYKKIIPWCKVFLKNESFTNFKGDEIAYALLYPMEKIFESYLTEEFKKSGKFETIVSQGNGYFLAKHKNE
GIFRLKPDIYAETSSKKYIMDAKWKILNSDKNKNYGISQNDMYQLLSYAVVYGCNELRLLYPKSKDFKRILEFEYNNSIN
YKEKISLKIIPIDLERNIADQIGFLL

Specific function: Modifies The Specificity Of Mcrb Restriction By Expanding The Range Of Modified Sequences Restricted. Does Not Bind To DNA. [C]

COG id: COG4268

COG function: function code V; McrBC 5-methylcytosine restriction system component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50080; Mature: 50080

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLKDITLNEFQYLIKGLNDEPHDRGFVINKHIFEKLELFVLKSKENSGCEFLRLTSLN
CCCCCCCCHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHEEEEECCCCCCCCEEEEECCC
GRKALQALNYVGIIKLKNGPTIEILPKINNDHISNEKVRRIFLKMLKSLKNAPFKEFGDA
CHHHHHHHCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCC
SLKTHKMKLNEIFIKIFLDDLDVLVKNGLKSDYISIEDNLNVLKGKIKFNEHISKNYIHK
CHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEEEEHHHHHHHCEEH
ERFYVNYDEFIRNRPENRIIKSTIKYLLKNSSLNSNLKRINEFLFIMDAIPESKNLEKDF
HHEEECHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
AACVNNRLMTDYKKIIPWCKVFLKNESFTNFKGDEIAYALLYPMEKIFESYLTEEFKKSG
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KFETIVSQGNGYFLAKHKNEGIFRLKPDIYAETSSKKYIMDAKWKILNSDKNKNYGISQN
CEEEEEECCCCEEEEEECCCCEEEECCCCEECCCCCEEEEECEEEEECCCCCCCCCCCHH
DMYQLLSYAVVYGCNELRLLYPKSKDFKRILEFEYNNSINYKEKISLKIIPIDLERNIAD
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHEECCCCCCCCEEEEEEEEEEECCCCHHH
QIGFLL
HHHCCC
>Mature Secondary Structure
MNNLKDITLNEFQYLIKGLNDEPHDRGFVINKHIFEKLELFVLKSKENSGCEFLRLTSLN
CCCCCCCCHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHEEEEECCCCCCCCEEEEECCC
GRKALQALNYVGIIKLKNGPTIEILPKINNDHISNEKVRRIFLKMLKSLKNAPFKEFGDA
CHHHHHHHCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCC
SLKTHKMKLNEIFIKIFLDDLDVLVKNGLKSDYISIEDNLNVLKGKIKFNEHISKNYIHK
CHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEEEEHHHHHHHCEEH
ERFYVNYDEFIRNRPENRIIKSTIKYLLKNSSLNSNLKRINEFLFIMDAIPESKNLEKDF
HHEEECHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
AACVNNRLMTDYKKIIPWCKVFLKNESFTNFKGDEIAYALLYPMEKIFESYLTEEFKKSG
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
KFETIVSQGNGYFLAKHKNEGIFRLKPDIYAETSSKKYIMDAKWKILNSDKNKNYGISQN
CEEEEEECCCCEEEEEECCCCEEEECCCCEECCCCCEEEEECEEEEECCCCCCCCCCCHH
DMYQLLSYAVVYGCNELRLLYPKSKDFKRILEFEYNNSINYKEKISLKIIPIDLERNIAD
HHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHEECCCCCCCCEEEEEEEEEEECCCCHHH
QIGFLL
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA