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The map label for this gene is ilvH [H]

Identifier: 45358214

GI number: 45358214

Start: 643154

End: 643663

Strand: Direct

Name: ilvH [H]

Synonym: MMP0651

Alternate gene names: 45358214

Gene position: 643154-643663 (Clockwise)

Preceding gene: 45358213

Following gene: 45358215

Centisome position: 38.72

GC content: 34.71

Gene sequence:

>510_bases
ATGGAACACAAACACATCATTTCAGTTTTGGTTTTGCACAAACCTGGCGTATTGCAGAGAATTTCAGGTTTGTTTACCAG
AAGATGGTTTAATATCTCAAGCATGACTGTTGGAAGCACTGAAAACCCTGATGTTGCAAGAATGACAATAGTTGTTCAGG
GAGATGATACAGTACTTGAACAGGTTGTAAAACAGTTGAATAAATTGGTAGAAGTTGTAAAAGTTACTGATTTAAACAGT
AACAAGTCAGTACAAAGAGAATTATGTCTTGTAAAAGTTTATGCGCCTACTGAAGATAGTAAATCTCAGGTAATCCAGTA
TGCAAATATATTTAGGGGAAAAATTATCGATTTAAGCACTGAAACACTCACTGTTGAAATTACTGGCGATGAGCAAAAAG
TAAACGCCTTTTTAGACCTTGTAAGGCCAATGGGCATAAAAGAAATTGCAAGAACTGGACTTACTGCTCTTATGAGGGGT
TCTAAAATTTTAAAATCAAATAAAGCATAA

Upstream 100 bases:

>100_bases
AATATATTATTCCCTGACCGACAGGAGCCAACTCCAAAAGCTCAATGCTTTAGCGAAATGAAAAAAATACTTAGTCCTAA
GGTCTAATCGGGTGATTGCA

Downstream 100 bases:

>100_bases
TTTTCTTTTTTAATCTTTAAATTAAATTTTAAACATTTTTAAAAATAGAAAAAAATTAAGCATTTTTTGAAGGGGGGCTC
CAAAAACAAATGCCTCAATT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MEHKHIISVLVLHKPGVLQRISGLFTRRWFNISSMTVGSTENPDVARMTIVVQGDDTVLEQVVKQLNKLVEVVKVTDLNS
NKSVQRELCLVKVYAPTEDSKSQVIQYANIFRGKIIDLSTETLTVEITGDEQKVNAFLDLVRPMGIKEIARTGLTALMRG
SKILKSNKA

Sequences:

>Translated_169_residues
MEHKHIISVLVLHKPGVLQRISGLFTRRWFNISSMTVGSTENPDVARMTIVVQGDDTVLEQVVKQLNKLVEVVKVTDLNS
NKSVQRELCLVKVYAPTEDSKSQVIQYANIFRGKIIDLSTETLTVEITGDEQKVNAFLDLVRPMGIKEIARTGLTALMRG
SKILKSNKA
>Mature_169_residues
MEHKHIISVLVLHKPGVLQRISGLFTRRWFNISSMTVGSTENPDVARMTIVVQGDDTVLEQVVKQLNKLVEVVKVTDLNS
NKSVQRELCLVKVYAPTEDSKSQVIQYANIFRGKIIDLSTETLTVEITGDEQKVNAFLDLVRPMGIKEIARTGLTALMRG
SKILKSNKA

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=163, Percent_Identity=42.9447852760736, Blast_Score=134, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319837, Length=204, Percent_Identity=30.8823529411765, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18875; Mature: 18875

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHKHIISVLVLHKPGVLQRISGLFTRRWFNISSMTVGSTENPDVARMTIVVQGDDTVLE
CCCHHEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEECCHHHHH
QVVKQLNKLVEVVKVTDLNSNKSVQRELCLVKVYAPTEDSKSQVIQYANIFRGKIIDLST
HHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHCCEEEEECC
ETLTVEITGDEQKVNAFLDLVRPMGIKEIARTGLTALMRGSKILKSNKA
CEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure
MEHKHIISVLVLHKPGVLQRISGLFTRRWFNISSMTVGSTENPDVARMTIVVQGDDTVLE
CCCHHEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEECCHHHHH
QVVKQLNKLVEVVKVTDLNSNKSVQRELCLVKVYAPTEDSKSQVIQYANIFRGKIIDLST
HHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHCCEEEEECC
ETLTVEITGDEQKVNAFLDLVRPMGIKEIARTGLTALMRGSKILKSNKA
CEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]