Click here to switch to the map view.

The map label for this gene is aIF-1A [H]

Identifier: 45358166

GI number: 45358166

Start: 598821

End: 599135

Strand: Direct

Name: aIF-1A [H]

Synonym: MMP0603

Alternate gene names: 45358166

Gene position: 598821-599135 (Clockwise)

Preceding gene: 45358161

Following gene: 45358167

Centisome position: 36.05

GC content: 40.63

Gene sequence:

>315_bases
ATGCGAGGACAACAAACACCCCCACAACAACCAACAAGAGTTAGGACTCCGCGAGAAAATGAAAATGAAGTTCTTGGAGT
AATCGAACAAATGCTTGGTGCAAGCAGAGTTAGAGTAAGATGTATGGATGGAAAACTCAGAATGGGCAGAATTCCTGGAA
AGTTAAAAAGAAAAATCTGGGTAAGGGAAGACGATGTTGTAATTGTTACCCCTTGGGAAGTTCAATCTGATGAGAAGTGC
GACGTAATCTGGAGATATACAAAAGGACAGGTTGACTGGTTAAATAGAAAAGGATACTTAGACTTCATGCGATAG

Upstream 100 bases:

>100_bases
TTAAAAATAAACGAATAACCTTCGTTTTACGTTTTTCTTTTGATTTCTTAAAACTATCGATTAACTAATTTTTTAAAATT
ATCAAAAAAAGGTGAAAACT

Downstream 100 bases:

>100_bases
GGATATTAATGAAAGATGTCCTTAAAATGGATTTAGATAAAAAAGAAAAACAGCTTGATAGGGAGTTTCAAAAAAAGATA
GTTGAACGAAAAAAGAAGTT

Product: translation initiation factor IF-1A

Products: NA

Alternate protein names: aIF-1A [H]

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MRGQQTPPQQPTRVRTPRENENEVLGVIEQMLGASRVRVRCMDGKLRMGRIPGKLKRKIWVREDDVVIVTPWEVQSDEKC
DVIWRYTKGQVDWLNRKGYLDFMR

Sequences:

>Translated_104_residues
MRGQQTPPQQPTRVRTPRENENEVLGVIEQMLGASRVRVRCMDGKLRMGRIPGKLKRKIWVREDDVVIVTPWEVQSDEKC
DVIWRYTKGQVDWLNRKGYLDFMR
>Mature_104_residues
MRGQQTPPQQPTRVRTPRENENEVLGVIEQMLGASRVRVRCMDGKLRMGRIPGKLKRKIWVREDDVVIVTPWEVQSDEKC
DVIWRYTKGQVDWLNRKGYLDFMR

Specific function: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits [H]

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323916, Length=73, Percent_Identity=38.3561643835616, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR006196
- InterPro:   IPR001253
- InterPro:   IPR018104
- ProDom:   PD005579 [H]

Pfam domain/function: PF01176 eIF-1a [H]

EC number: NA

Molecular weight: Translated: 12356; Mature: 12356

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS50832 S1_IF1_TYPE ; PS01262 IF1A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGQQTPPQQPTRVRTPRENENEVLGVIEQMLGASRVRVRCMDGKLRMGRIPGKLKRKIW
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEECCCCCCHHHEEE
VREDDVVIVTPWEVQSDEKCDVIWRYTKGQVDWLNRKGYLDFMR
ECCCCEEEEECCCCCCCCCCEEEEEECCCCEEEECCCCCEEECC
>Mature Secondary Structure
MRGQQTPPQQPTRVRTPRENENEVLGVIEQMLGASRVRVRCMDGKLRMGRIPGKLKRKIW
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCEEECCCCCCHHHEEE
VREDDVVIVTPWEVQSDEKCDVIWRYTKGQVDWLNRKGYLDFMR
ECCCCEEEEECCCCCCCCCCEEEEEECCCCEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA