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The map label for this gene is rio1 [H]

Identifier: 45358167

GI number: 45358167

Start: 599144

End: 599965

Strand: Direct

Name: rio1 [H]

Synonym: MMP0604

Alternate gene names: 45358167

Gene position: 599144-599965 (Clockwise)

Preceding gene: 45358166

Following gene: 45358168

Centisome position: 36.07

GC content: 32.6

Gene sequence:

>822_bases
ATGAAAGATGTCCTTAAAATGGATTTAGATAAAAAAGAAAAACAGCTTGATAGGGAGTTTCAAAAAAAGATAGTTGAACG
AAAAAAGAAGTTTTTGGAAGAATTAAAAACTGAAAATGAAGTTTTTGATCAACGTACTCTCTTAAATATTTATAATTTAC
TTGTCGCAAAACACATTGACGAAATTTCAGGAGTTGTTAATTCCGGAAAAGAAGCAGTGGTATTTTCTGCGAATAAAGAG
GATGAACTCTACGCATTAAAGGTTTATCGTGTTTCCACTTGTGATTTTAAAACAATGTGGAAATATATTCGGGGTGATCC
TCGATTCCACCTTAGAAGAAGCAGTACTCGACAGATAATAACTGCATGGGTGGAAAAAGAATTTAGAAACCTTTTAAGGG
CAGGAGATTATATAAACACGCCAGAACCACTATTAAAGCGAGAAAATATTCTTTTAATGGATATGGTTCATGAAGATGGA
GTTCCAGCTCCAAGATTGAAAGATATTGAAGTCGATTATTCCGAATTTTATGAAATGATAAAAGAAGATATGAAAGTATT
GTATCAAGATGCCCAGTTAGTTCACGGGGATCTTTCTGAATATAATATCTTAGTACACGAAGAAGAGCCAGTATATATTG
ACTTTTCACAAGGGGTTGTTAAAGAACATCCTCTTTCAAAAACACTCCTAATTAGGGATGTTAAGAACGTATGTAACTTC
TTTAAAAGAAAAGGAATCGATACGGACTACAAAGAGTTTTACAAGTTTGTTTCTGGAGAAGAACTTGCATTAATTGATGA
AGAAATGGCAAAAACATATTAA

Upstream 100 bases:

>100_bases
AATCTGATGAGAAGTGCGACGTAATCTGGAGATATACAAAAGGACAGGTTGACTGGTTAAATAGAAAAGGATACTTAGAC
TTCATGCGATAGGGATATTA

Downstream 100 bases:

>100_bases
TAAAATTTCTACAAAATCTTTTTTTAAGTATAAATTATATAATATTTAACGAAATTTAACTGCGTAATTGGTGAGATTTT
ATGTACGAGAATGTGGAAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MKDVLKMDLDKKEKQLDREFQKKIVERKKKFLEELKTENEVFDQRTLLNIYNLLVAKHIDEISGVVNSGKEAVVFSANKE
DELYALKVYRVSTCDFKTMWKYIRGDPRFHLRRSSTRQIITAWVEKEFRNLLRAGDYINTPEPLLKRENILLMDMVHEDG
VPAPRLKDIEVDYSEFYEMIKEDMKVLYQDAQLVHGDLSEYNILVHEEEPVYIDFSQGVVKEHPLSKTLLIRDVKNVCNF
FKRKGIDTDYKEFYKFVSGEELALIDEEMAKTY

Sequences:

>Translated_273_residues
MKDVLKMDLDKKEKQLDREFQKKIVERKKKFLEELKTENEVFDQRTLLNIYNLLVAKHIDEISGVVNSGKEAVVFSANKE
DELYALKVYRVSTCDFKTMWKYIRGDPRFHLRRSSTRQIITAWVEKEFRNLLRAGDYINTPEPLLKRENILLMDMVHEDG
VPAPRLKDIEVDYSEFYEMIKEDMKVLYQDAQLVHGDLSEYNILVHEEEPVYIDFSQGVVKEHPLSKTLLIRDVKNVCNF
FKRKGIDTDYKEFYKFVSGEELALIDEEMAKTY
>Mature_273_residues
MKDVLKMDLDKKEKQLDREFQKKIVERKKKFLEELKTENEVFDQRTLLNIYNLLVAKHIDEISGVVNSGKEAVVFSANKE
DELYALKVYRVSTCDFKTMWKYIRGDPRFHLRRSSTRQIITAWVEKEFRNLLRAGDYINTPEPLLKRENILLMDMVHEDG
VPAPRLKDIEVDYSEFYEMIKEDMKVLYQDAQLVHGDLSEYNILVHEEEPVYIDFSQGVVKEHPLSKTLLIRDVKNVCNF
FKRKGIDTDYKEFYKFVSGEELALIDEEMAKTY

Specific function: Unknown

COG id: COG1718

COG function: function code TD; Serine/threonine protein kinase involved in cell cycle control

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI23510356, Length=230, Percent_Identity=36.9565217391304, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI22325377, Length=259, Percent_Identity=36.6795366795367, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI23510358, Length=145, Percent_Identity=38.6206896551724, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI115532073, Length=216, Percent_Identity=37.037037037037, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17556977, Length=223, Percent_Identity=32.7354260089686, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71989043, Length=135, Percent_Identity=36.2962962962963, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324693, Length=258, Percent_Identity=32.9457364341085, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24662811, Length=239, Percent_Identity=37.2384937238494, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21356879, Length=239, Percent_Identity=37.2384937238494, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19920700, Length=257, Percent_Identity=31.9066147859922, Blast_Score=127, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR018934
- InterPro:   IPR000687
- InterPro:   IPR018935
- InterPro:   IPR008266 [H]

Pfam domain/function: PF01163 RIO1 [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 32382; Mature: 32382

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS01245 RIO1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVLKMDLDKKEKQLDREFQKKIVERKKKFLEELKTENEVFDQRTLLNIYNLLVAKHID
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EISGVVNSGKEAVVFSANKEDELYALKVYRVSTCDFKTMWKYIRGDPRFHLRRSSTRQII
HHHHHHHCCCCEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCEEEECHHHHHHH
TAWVEKEFRNLLRAGDYINTPEPLLKRENILLMDMVHEDGVPAPRLKDIEVDYSEFYEMI
HHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEEHHCCCCCCCCCCCCCCCHHHHHHHH
KEDMKVLYQDAQLVHGDLSEYNILVHEEEPVYIDFSQGVVKEHPLSKTLLIRDVKNVCNF
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCHHHCCCCHHHHHHHHHHHHHH
FKRKGIDTDYKEFYKFVSGEELALIDEEMAKTY
HHHCCCCCCHHHHHHHHCCCCEEEHHHHHHHCC
>Mature Secondary Structure
MKDVLKMDLDKKEKQLDREFQKKIVERKKKFLEELKTENEVFDQRTLLNIYNLLVAKHID
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EISGVVNSGKEAVVFSANKEDELYALKVYRVSTCDFKTMWKYIRGDPRFHLRRSSTRQII
HHHHHHHCCCCEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCEEEECHHHHHHH
TAWVEKEFRNLLRAGDYINTPEPLLKRENILLMDMVHEDGVPAPRLKDIEVDYSEFYEMI
HHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEEHHCCCCCCCCCCCCCCCHHHHHHHH
KEDMKVLYQDAQLVHGDLSEYNILVHEEEPVYIDFSQGVVKEHPLSKTLLIRDVKNVCNF
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCHHHCCCCHHHHHHHHHHHHHH
FKRKGIDTDYKEFYKFVSGEELALIDEEMAKTY
HHHCCCCCCHHHHHHHHCCCCEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]