Click here to switch to the map view.

The map label for this gene is tlpC [H]

Identifier: 45358050

GI number: 45358050

Start: 483526

End: 485715

Strand: Direct

Name: tlpC [H]

Synonym: MMP0487

Alternate gene names: 45358050

Gene position: 483526-485715 (Clockwise)

Preceding gene: 45358049

Following gene: 45358059

Centisome position: 29.11

GC content: 33.97

Gene sequence:

>2190_bases
TTGAAAATAAGTTTTAAAAAAATCGGTACAAAACTACTGATATTTATGATACTTTGTGCGATAATCCCGCTAATGGTAGT
TGGAGGGGTTTCCACCAATAAAATAACCGAAGAAATGCAAATACAAGGGGACAATAGCGTTAATGATAATTTAAACATAT
TTCAAGAATCGATAGAAAATGTAATCGTTGAATTTGAAACAACCACAAGCTACACGGCAAGTTTAGATACATTTTCAGAA
TTACTTGTAAATGATGATAAAGAAGTGCTTTATGATTTTGCAGAAAAGATGAAGAAATCATCTGAAGTAGATCTGGTTGC
ATTTACAGATAAAAATGGTAATATTATATCTTCATCTGATAATGTGCAGACGAATTTAAAACCTGTAATCTCAAAATTAC
TTAGTAATGAGGTCCAGAGTTCGTTTGAAATAATTTCTGGATCTGAAGCTTCAAAATACAGTGATTATAAAGTAAATAAC
ATAAATGATGCTCTTGCAATCTGCGTGGTTGCTCCTGTTTATCATTCAGGGGAACTTGTAGGTACTGTAACACTTGTAGA
TATTGTAAATAATGACGATTACTGGGTAGATAGCCTTAAAGAGCGAACCGGTAACGAAGCTACAATATTCCTTAAAAATG
TCAGGATTTCTACAACTGTTCAAACCAATGGACAGGATGCAACTGGAACAAAATGTTCTGATGAAGTTTACAATATAATA
ACAAATCATCAAGATTATGTTGGAACTGCAAACGTACTTGGAAGTGAATATATTACCAAATATTCTCCAATAGAAGATAA
GGACGGAAATGTAGTTGGTATTATATTTACAGGCATTCCAAAAGCCCCATTCGTTGCAGTTATAACTGATACGAGAAATG
AAATAATTATAATATCATTATTGGGACTTTTACTTTCAATTTTGATTGCATTATACACTGGAAGAAAAATTACAAAACCA
ATCGAAGAACTCAAAAAAGGAACTGAAGAATTTGGTAATGGAAACTACGACTACAAAACAACTGTCAAAACTGGCGATGA
ATTGCAAGAACTTTCAGATTCATTCAATAAAATGGCTGAAAATGTTAAGAATTTAATGAAAACAATGGATATGGACAAGG
TAGAACTTGCAACGCTCCTTACTAACGTATCCGATGTAATGAACAGGGTTGCAAAAGGAGATTTTACAGCAAGAGCTGAT
GAATCTCGTGAAAATAACAACCTTGAAAAAGCGATTAACACTGCAGTTTCAAATGTTGCAGATTTAATTAAAGAATTGCG
AGAAGAAGTGGAGTTACTTAATATTCAAATTCAAAAAGTTGAAGATGAATTAAAAGGCGCAGAAGAAACAGCCACCCAAG
TTGCAGAGGCAGCAACTCAGGTTGCAGAGGCCGCAAGTGATCAGTCTGCAAAACTACAAGAATCATCTGAAGAACTTGAA
AATACTTATGAAGGCGCAAAAGAAGTTTACAGCGCAGCAGAAGAAACTGTCAAATCATCTGAAGAAATCAAAGAAAACTC
TGAAACAGGAGTTGAAAAGGTTGAAAACGCAATTTCAAGAATGCAATCAATAACAAATGTGATTGATGAGCTTGGAAAAT
CAATCAAAATGCTTGGGGAAGACGGTAAAAAAATTAATGAAGTTACGGGATTAATTAAAGATATTGCTGAACAAACTGGA
CTTTTGGCACTTAATGCATCAATTGAAGCTGCTCGTGCAGGAGATGCCGGAAAAGGCTTTGCAGTCGTTGCAAGTGAAAT
TAAATCTTTAGCAGAAGAAATCAAAAAGTCAGTTGAGGACATAAACCATACAATTGAAGGAGTAAATAAAAGAATCGACG
ACACAATTGACCTTGGTTTAAAAGGAAAAGATGAAGTGGACAAAGGAGTAATTGCAATTGATGAGGTAAATGACGCACTT
TTAAAAATTAAAGAAAGTGTCAATGAGTCCGCAGTTAAAATAAACGGAATTAAACATGGTGCACAAAATGCTTCTGAAAA
TACCGAAGGAGCTTTAAAAAATGCACAAGAAATTGCTGCACTATCAGAAGAATTTACTGCAACCGCAGAAGAAGTAACTG
CTTCAACTGAGGAATTAAACTCAATCATTGAAGAAATCCGAGGTATTGCAGAAGAAGTAACACAAGTTGCAGAAAGAGTA
ACTAAAAAATCAAGTCAATTCAAAATCTAA

Upstream 100 bases:

>100_bases
TTTAGTTACCTACATAAAAATCATATATACCTCAATAAATAGACAGATTCCCGTTAAAAATACTAACCCATCATATTAAT
CCAAGACATAGGTGACTTAT

Downstream 100 bases:

>100_bases
ATTCTTTTTTTATTTTTTATAACAATTTTTTGTAAATTAACTTTAGAAATTTTAAAAAAGATAAAATTATGATTTAAAAC
GATTTTTCAGTAAATTTCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MKISFKKIGTKLLIFMILCAIIPLMVVGGVSTNKITEEMQIQGDNSVNDNLNIFQESIENVIVEFETTTSYTASLDTFSE
LLVNDDKEVLYDFAEKMKKSSEVDLVAFTDKNGNIISSSDNVQTNLKPVISKLLSNEVQSSFEIISGSEASKYSDYKVNN
INDALAICVVAPVYHSGELVGTVTLVDIVNNDDYWVDSLKERTGNEATIFLKNVRISTTVQTNGQDATGTKCSDEVYNII
TNHQDYVGTANVLGSEYITKYSPIEDKDGNVVGIIFTGIPKAPFVAVITDTRNEIIIISLLGLLLSILIALYTGRKITKP
IEELKKGTEEFGNGNYDYKTTVKTGDELQELSDSFNKMAENVKNLMKTMDMDKVELATLLTNVSDVMNRVAKGDFTARAD
ESRENNNLEKAINTAVSNVADLIKELREEVELLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSEELE
NTYEGAKEVYSAAEETVKSSEEIKENSETGVEKVENAISRMQSITNVIDELGKSIKMLGEDGKKINEVTGLIKDIAEQTG
LLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVEDINHTIEGVNKRIDDTIDLGLKGKDEVDKGVIAIDEVNDAL
LKIKESVNESAVKINGIKHGAQNASENTEGALKNAQEIAALSEEFTATAEEVTASTEELNSIIEEIRGIAEEVTQVAERV
TKKSSQFKI

Sequences:

>Translated_729_residues
MKISFKKIGTKLLIFMILCAIIPLMVVGGVSTNKITEEMQIQGDNSVNDNLNIFQESIENVIVEFETTTSYTASLDTFSE
LLVNDDKEVLYDFAEKMKKSSEVDLVAFTDKNGNIISSSDNVQTNLKPVISKLLSNEVQSSFEIISGSEASKYSDYKVNN
INDALAICVVAPVYHSGELVGTVTLVDIVNNDDYWVDSLKERTGNEATIFLKNVRISTTVQTNGQDATGTKCSDEVYNII
TNHQDYVGTANVLGSEYITKYSPIEDKDGNVVGIIFTGIPKAPFVAVITDTRNEIIIISLLGLLLSILIALYTGRKITKP
IEELKKGTEEFGNGNYDYKTTVKTGDELQELSDSFNKMAENVKNLMKTMDMDKVELATLLTNVSDVMNRVAKGDFTARAD
ESRENNNLEKAINTAVSNVADLIKELREEVELLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSEELE
NTYEGAKEVYSAAEETVKSSEEIKENSETGVEKVENAISRMQSITNVIDELGKSIKMLGEDGKKINEVTGLIKDIAEQTG
LLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVEDINHTIEGVNKRIDDTIDLGLKGKDEVDKGVIAIDEVNDAL
LKIKESVNESAVKINGIKHGAQNASENTEGALKNAQEIAALSEEFTATAEEVTASTEELNSIIEEIRGIAEEVTQVAERV
TKKSSQFKI
>Mature_729_residues
MKISFKKIGTKLLIFMILCAIIPLMVVGGVSTNKITEEMQIQGDNSVNDNLNIFQESIENVIVEFETTTSYTASLDTFSE
LLVNDDKEVLYDFAEKMKKSSEVDLVAFTDKNGNIISSSDNVQTNLKPVISKLLSNEVQSSFEIISGSEASKYSDYKVNN
INDALAICVVAPVYHSGELVGTVTLVDIVNNDDYWVDSLKERTGNEATIFLKNVRISTTVQTNGQDATGTKCSDEVYNII
TNHQDYVGTANVLGSEYITKYSPIEDKDGNVVGIIFTGIPKAPFVAVITDTRNEIIIISLLGLLLSILIALYTGRKITKP
IEELKKGTEEFGNGNYDYKTTVKTGDELQELSDSFNKMAENVKNLMKTMDMDKVELATLLTNVSDVMNRVAKGDFTARAD
ESRENNNLEKAINTAVSNVADLIKELREEVELLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSEELE
NTYEGAKEVYSAAEETVKSSEEIKENSETGVEKVENAISRMQSITNVIDELGKSIKMLGEDGKKINEVTGLIKDIAEQTG
LLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVEDINHTIEGVNKRIDDTIDLGLKGKDEVDKGVIAIDEVNDAL
LKIKESVNESAVKINGIKHGAQNASENTEGALKNAQEIAALSEEFTATAEEVTASTEELNSIIEEIRGIAEEVTQVAERV
TKKSSQFKI

Specific function: Mediates Taxis To The Sugars Ribose And Galactose VIa An Interaction With The Periplasmic Ribose- Or Galactose-Binding Proteins. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of Attractants And Repellents In The Environment, Trans

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=307, Percent_Identity=26.7100977198697, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788195, Length=225, Percent_Identity=27.5555555555556, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI2367378, Length=164, Percent_Identity=30.4878048780488, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789453, Length=271, Percent_Identity=28.0442804428044, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788194, Length=262, Percent_Identity=26.3358778625954, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 79512; Mature: 79512

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISFKKIGTKLLIFMILCAIIPLMVVGGVSTNKITEEMQIQGDNSVNDNLNIFQESIEN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VIVEFETTTSYTASLDTFSELLVNDDKEVLYDFAEKMKKSSEVDLVAFTDKNGNIISSSD
HEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEECCCC
NVQTNLKPVISKLLSNEVQSSFEIISGSEASKYSDYKVNNINDALAICVVAPVYHSGELV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
GTVTLVDIVNNDDYWVDSLKERTGNEATIFLKNVRISTTVQTNGQDATGTKCSDEVYNII
EEEEEEEEECCCCHHHHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCHHHHHHHH
TNHQDYVGTANVLGSEYITKYSPIEDKDGNVVGIIFTGIPKAPFVAVITDTRNEIIIISL
HCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCEEHHHH
LGLLLSILIALYTGRKITKPIEELKKGTEEFGNGNYDYKTTVKTGDELQELSDSFNKMAE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHH
NVKNLMKTMDMDKVELATLLTNVSDVMNRVAKGDFTARADESRENNNLEKAINTAVSNVA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
DLIKELREEVELLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSEELE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NTYEGAKEVYSAAEETVKSSEEIKENSETGVEKVENAISRMQSITNVIDELGKSIKMLGE
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGKKINEVTGLIKDIAEQTGLLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVED
CCHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
INHTIEGVNKRIDDTIDLGLKGKDEVDKGVIAIDEVNDALLKIKESVNESAVKINGIKHG
HHHHHHHHHHHCCHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEECCCCCC
AQNASENTEGALKNAQEIAALSEEFTATAEEVTASTEELNSIIEEIRGIAEEVTQVAERV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKKSSQFKI
HHCCCCCCC
>Mature Secondary Structure
MKISFKKIGTKLLIFMILCAIIPLMVVGGVSTNKITEEMQIQGDNSVNDNLNIFQESIEN
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VIVEFETTTSYTASLDTFSELLVNDDKEVLYDFAEKMKKSSEVDLVAFTDKNGNIISSSD
HEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEECCCC
NVQTNLKPVISKLLSNEVQSSFEIISGSEASKYSDYKVNNINDALAICVVAPVYHSGELV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEE
GTVTLVDIVNNDDYWVDSLKERTGNEATIFLKNVRISTTVQTNGQDATGTKCSDEVYNII
EEEEEEEEECCCCHHHHHHHHCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCHHHHHHHH
TNHQDYVGTANVLGSEYITKYSPIEDKDGNVVGIIFTGIPKAPFVAVITDTRNEIIIISL
HCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCEEHHHH
LGLLLSILIALYTGRKITKPIEELKKGTEEFGNGNYDYKTTVKTGDELQELSDSFNKMAE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHH
NVKNLMKTMDMDKVELATLLTNVSDVMNRVAKGDFTARADESRENNNLEKAINTAVSNVA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
DLIKELREEVELLNIQIQKVEDELKGAEETATQVAEAATQVAEAASDQSAKLQESSEELE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
NTYEGAKEVYSAAEETVKSSEEIKENSETGVEKVENAISRMQSITNVIDELGKSIKMLGE
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGKKINEVTGLIKDIAEQTGLLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVED
CCHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
INHTIEGVNKRIDDTIDLGLKGKDEVDKGVIAIDEVNDALLKIKESVNESAVKINGIKHG
HHHHHHHHHHHCCHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCEEECCCCCC
AQNASENTEGALKNAQEIAALSEEFTATAEEVTASTEELNSIIEEIRGIAEEVTQVAERV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKKSSQFKI
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]