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The map label for this gene is rpoE1 [H]

Identifier: 45358003

GI number: 45358003

Start: 439634

End: 440197

Strand: Direct

Name: rpoE1 [H]

Synonym: MMP0440

Alternate gene names: 45358003

Gene position: 439634-440197 (Clockwise)

Preceding gene: 45358002

Following gene: 45358004

Centisome position: 26.47

GC content: 37.41

Gene sequence:

>564_bases
TTGTACAAAATTTTAAAAATTTCTGATACCGTGAGAATTCCCCCTAAAATGTTTGGAAACCCGTTAAGCGAAAACGTAAA
AAGGGTTTTAATGGAAAAATACGAAGGAATTCTTGATAAGGACATCGGATTTATCCTTTCAATCGTTGATGTGGATAACG
TAAGCGACGGAAGCATAATTTACGGGGACGGTGCAGCATACCACGAAACAGAATTTAATGTGCTTACATACGTTCCAGAA
CTTCAGGAAGTAGTTGACGGAGAAATCGTCGATGTTGTTGAGTTCGGTGCTTTTGTAAGACTTGGCCCTCTTGACGGTTT
AATCCACATTTCACAAATTATGGATGACTTCGTAAGCTTTGACCCAAAAAGAGAAGCAATTATTGGAAAAGAAACAGGCA
AAGTTTTAGAAAAAGGCGACAAAGTAAGAGCTAGAATTGTTGCAGTAAGTTTAAGAGAAGAGAAGAAAAGAGGCAGTAAA
ATTGCTTTAACAATGAGACAGAACGGTCTTGGAAGACTTGAATGGCTCGAAGATGAAAACGAAACACTAAGTGAAGAAAA
TTAA

Upstream 100 bases:

>100_bases
ACCAAAAACGAGAATATATATAGTGAAACTGTTTTATTATTTTAAAATATTTCGTTATCTCAACTGTTTTAAAAGTTTAA
TCTGCTACTGAGGTGGTTAT

Downstream 100 bases:

>100_bases
TTTTTTCACCATTATTTCTATTTAATTTTAATTTGAGGTGAATTTAAATGAATGCATGTTTAAGATGCAAATACATCACA
AAAGAAGATACCTGCCCGAT

Product: DNA-directed RNA polymerase subunit E'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MYKILKISDTVRIPPKMFGNPLSENVKRVLMEKYEGILDKDIGFILSIVDVDNVSDGSIIYGDGAAYHETEFNVLTYVPE
LQEVVDGEIVDVVEFGAFVRLGPLDGLIHISQIMDDFVSFDPKREAIIGKETGKVLEKGDKVRARIVAVSLREEKKRGSK
IALTMRQNGLGRLEWLEDENETLSEEN

Sequences:

>Translated_187_residues
MYKILKISDTVRIPPKMFGNPLSENVKRVLMEKYEGILDKDIGFILSIVDVDNVSDGSIIYGDGAAYHETEFNVLTYVPE
LQEVVDGEIVDVVEFGAFVRLGPLDGLIHISQIMDDFVSFDPKREAIIGKETGKVLEKGDKVRARIVAVSLREEKKRGSK
IALTMRQNGLGRLEWLEDENETLSEEN
>Mature_187_residues
MYKILKISDTVRIPPKMFGNPLSENVKRVLMEKYEGILDKDIGFILSIVDVDNVSDGSIIYGDGAAYHETEFNVLTYVPE
LQEVVDGEIVDVVEFGAFVRLGPLDGLIHISQIMDDFVSFDPKREAIIGKETGKVLEKGDKVRARIVAVSLREEKKRGSK
IALTMRQNGLGRLEWLEDENETLSEEN

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG1095

COG function: function code K; DNA-directed RNA polymerase, subunit E'

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI24475814, Length=168, Percent_Identity=24.4047619047619, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI65301161, Length=168, Percent_Identity=24.4047619047619, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI4505947, Length=150, Percent_Identity=26, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17510349, Length=151, Percent_Identity=27.8145695364238, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322705, Length=150, Percent_Identity=28, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR005576
- InterPro:   IPR004519 [H]

Pfam domain/function: PF03876 RNA_pol_Rpb7_N; PF00575 S1 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 21030; Mature: 21030

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKILKISDTVRIPPKMFGNPLSENVKRVLMEKYEGILDKDIGFILSIVDVDNVSDGSII
CEEEEEECCCEECCHHHCCCCHHHHHHHHHHHHHHCHHCCCHHHEEEEEECCCCCCCCEE
YGDGAAYHETEFNVLTYVPELQEVVDGEIVDVVEFGAFVRLGPLDGLIHISQIMDDFVSF
ECCCCEEECCCCCCEEECHHHHHHHCCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCC
DPKREAIIGKETGKVLEKGDKVRARIVAVSLREEKKRGSKIALTMRQNGLGRLEWLEDEN
CCCHHEEECCHHHHHHHCCCCEEEEEEEEEHHHHHCCCCEEEEEEECCCCCCEEEECCCC
ETLSEEN
CCCCCCC
>Mature Secondary Structure
MYKILKISDTVRIPPKMFGNPLSENVKRVLMEKYEGILDKDIGFILSIVDVDNVSDGSII
CEEEEEECCCEECCHHHCCCCHHHHHHHHHHHHHHCHHCCCHHHEEEEEECCCCCCCCEE
YGDGAAYHETEFNVLTYVPELQEVVDGEIVDVVEFGAFVRLGPLDGLIHISQIMDDFVSF
ECCCCEEECCCCCCEEECHHHHHHHCCCHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCC
DPKREAIIGKETGKVLEKGDKVRARIVAVSLREEKKRGSKIALTMRQNGLGRLEWLEDEN
CCCHHEEECCHHHHHHHCCCCEEEEEEEEEHHHHHCCCCEEEEEEECCCCCCEEEECCCC
ETLSEEN
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]