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The map label for this gene is tlpC [H]

Identifier: 45357976

GI number: 45357976

Start: 411833

End: 414028

Strand: Direct

Name: tlpC [H]

Synonym: MMP0413

Alternate gene names: 45357976

Gene position: 411833-414028 (Clockwise)

Preceding gene: 45357975

Following gene: 45357978

Centisome position: 24.79

GC content: 35.56

Gene sequence:

>2196_bases
ATGAAATTGGGTACTAAAAAAATTGGAACAAAACTTTTAATATTTTCAATAATAACAGTCATAATTCCAATTGCGATCCT
CGGCATTGTTTCAAATAATACTATTACACAGGATATGAAGGAACAATCTGCGGATAAATTGGAATCAAGCAATGAGATGG
CAAATACCATCATGGACAGTAGATTTACCGAACTTTGTACTTTGGCAGAATATGCCTCATACACTCAAGGTGTAAAAACC
AGTATCAAAACTGGAAATGTAGATGACCTTGAATTAAGGGCTGAAACGCTCAAAAGTGCTTCTAACGCTGATTTGGTAAT
ATTTACGGGTAATGGGGGAAGTACAATTGCTTCTTCATCTGGTGAAGGTATAACATTAGATTCAACAATTTTAAAAGTTT
CAAAATCCTCCGAGAAATCAGGATTCGAAAAAATACCTGAACAAACTGCTTTAAAATTTAGTGACGCAGACGTTACAGGC
ACTGATTCGGCACTATCAATTGTAGTGGCGTATCCTATCTATGATGATGCAGGAACACTTGGATATGTTGCATTCATCGA
TGTTTTAAATAATGATCATACTTTGGTTGATAGTATAAAAGCTTCAACTGGTGACGAATCTACGCTATTTTTAGAAAATT
ACAGAATATCTACGAGTGTAGTTTCTGGAAATAGCCGAGCTGTGGGAACTACTGCATCAGATGTGGTATATAACACAGTT
GTAAAAGAAAACACTGAATTTATGGGTAGTGCAAATGTTGTTGGACAAAGTTTCCTTACAAAATATGTACCGCTGAAAGA
TTCGAATGGCGCTACAATAGGCATGGTCTTTGTTGGAACTCCAGAAGCTCAATTTACACAATTAGTCAACAATGCAAGAA
ATAATACAATAATTATTGCATTATTCGGACTGTTAATTGCTGTGGTTATTTCTTTAGTTTCTTCAAGAAGTATTACCAAG
CCCATCAATCAATTAGAAGACGGGGTACATAAATTTGGTAGCGGAGATTATGATCACACAATAAATGTGAAAACTGGCGA
TGAATTAGAAGAACTAGCAAATTCGTTCAATAAAATGGCCAAAGACATTAAAGAACTGCACTCAATGCTGGATGCGGATA
AATTATCCCTTGCAAAAACATTAAAAGAAATATTTGATATTATGGATCATCTTGCAGAAGGGGACTTTTCAGTAAGGGCT
GATGAAAACAGGCACAAGAATAAACTTCAAAAAACAATCAACCATGCAATTGAAAATGTTTCAAAAATGATGGAAAATTT
GAAGTCAGAAATCACTGTATTAAGTGACGAACTTGAAGATGTTGGGGAAGGACTGAAAAGAGCTAAAGAAACTTCAGAAC
AGGTTACTGATGCTGCAAATCAGGTTGCAACTGCTGCAGCTGATCAATCCGCAAAATTACAGGATACTTCAGACGAACTT
GAAAAAACTGCGAAAGCTGCAGATATGGTATATAATGATGCAGAACAGAGCGTTGATTCAGCAATCGAAGTAAAAGATAA
TTCCGAAACCGGCGTTAAAAAAGTTGAAAATGCAATAGACACCATGCAGAAAATTACGAACGTAATTGACGAACTTGGAA
AATCTATTCAAGAACTTGGGGAAGAATCCAAAAAAATCAACGAAGTTACAGTTTTAATTAAAGACGTTGCAGAACAGACT
GGACTTTTAGCACTAAATGCATCAATTGAAGCTGCTCGTGCAGGAGATGCCGGAAAAGGCTTTGCAGTCGTTGCAAGTGA
AATTAAATCTTTAGCAGAAGAAATTAAGAAATCCGTTGAAGATATCAATAGAACAATCAATGGAATTAACAAAAAAGTTG
AAACAACAATTGATTTAGGCCTTGCAGGAAGAGATGAAGTTGATAGGGGAGTTGTTGCAATTGATGAAGTTAACAGCGCA
TTTATGAAAATAAAAGAAAGCGTTGAAACATCCGCAAAAATGATTGCACAAATCAAAGACAATGCTAAAAATGCATCGAA
CAATACTCAAGAAGCACTTAGAAACGTGCAGGATATTGCATCAATTTCCGAAGAGTTTGCAGCAACAGCAGAAGAGCTAA
CCGCATCCTCAGAAGAACAAAATAGGGCTGTTGAAGAAATAGATGCTTCAGCAGAGAAAATGATGGAAATATCAAGAAAA
TTAGCAGAAGATGCAGATGAATTTAAAACTAAATAA

Upstream 100 bases:

>100_bases
TTTTCAACCTTAAATCGGTGTACCTACACAAAGACCCACATAAAAACAATATATAGTTAGGATTTGACAGAATAATTGGG
GAGATATAAAGGTGTCACTA

Downstream 100 bases:

>100_bases
ATACTCTTTTTACTATTTTTAATTATTTCAAAAAAGATTTTAAAAAAGTTTAAAAATTTAAATTATCTAAAGATAGGCTG
CATTGAGCACTTCATTGGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 731; Mature: 731

Protein sequence:

>731_residues
MKLGTKKIGTKLLIFSIITVIIPIAILGIVSNNTITQDMKEQSADKLESSNEMANTIMDSRFTELCTLAEYASYTQGVKT
SIKTGNVDDLELRAETLKSASNADLVIFTGNGGSTIASSSGEGITLDSTILKVSKSSEKSGFEKIPEQTALKFSDADVTG
TDSALSIVVAYPIYDDAGTLGYVAFIDVLNNDHTLVDSIKASTGDESTLFLENYRISTSVVSGNSRAVGTTASDVVYNTV
VKENTEFMGSANVVGQSFLTKYVPLKDSNGATIGMVFVGTPEAQFTQLVNNARNNTIIIALFGLLIAVVISLVSSRSITK
PINQLEDGVHKFGSGDYDHTINVKTGDELEELANSFNKMAKDIKELHSMLDADKLSLAKTLKEIFDIMDHLAEGDFSVRA
DENRHKNKLQKTINHAIENVSKMMENLKSEITVLSDELEDVGEGLKRAKETSEQVTDAANQVATAAADQSAKLQDTSDEL
EKTAKAADMVYNDAEQSVDSAIEVKDNSETGVKKVENAIDTMQKITNVIDELGKSIQELGEESKKINEVTVLIKDVAEQT
GLLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVEDINRTINGINKKVETTIDLGLAGRDEVDRGVVAIDEVNSA
FMKIKESVETSAKMIAQIKDNAKNASNNTQEALRNVQDIASISEEFAATAEELTASSEEQNRAVEEIDASAEKMMEISRK
LAEDADEFKTK

Sequences:

>Translated_731_residues
MKLGTKKIGTKLLIFSIITVIIPIAILGIVSNNTITQDMKEQSADKLESSNEMANTIMDSRFTELCTLAEYASYTQGVKT
SIKTGNVDDLELRAETLKSASNADLVIFTGNGGSTIASSSGEGITLDSTILKVSKSSEKSGFEKIPEQTALKFSDADVTG
TDSALSIVVAYPIYDDAGTLGYVAFIDVLNNDHTLVDSIKASTGDESTLFLENYRISTSVVSGNSRAVGTTASDVVYNTV
VKENTEFMGSANVVGQSFLTKYVPLKDSNGATIGMVFVGTPEAQFTQLVNNARNNTIIIALFGLLIAVVISLVSSRSITK
PINQLEDGVHKFGSGDYDHTINVKTGDELEELANSFNKMAKDIKELHSMLDADKLSLAKTLKEIFDIMDHLAEGDFSVRA
DENRHKNKLQKTINHAIENVSKMMENLKSEITVLSDELEDVGEGLKRAKETSEQVTDAANQVATAAADQSAKLQDTSDEL
EKTAKAADMVYNDAEQSVDSAIEVKDNSETGVKKVENAIDTMQKITNVIDELGKSIQELGEESKKINEVTVLIKDVAEQT
GLLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVEDINRTINGINKKVETTIDLGLAGRDEVDRGVVAIDEVNSA
FMKIKESVETSAKMIAQIKDNAKNASNNTQEALRNVQDIASISEEFAATAEELTASSEEQNRAVEEIDASAEKMMEISRK
LAEDADEFKTK
>Mature_731_residues
MKLGTKKIGTKLLIFSIITVIIPIAILGIVSNNTITQDMKEQSADKLESSNEMANTIMDSRFTELCTLAEYASYTQGVKT
SIKTGNVDDLELRAETLKSASNADLVIFTGNGGSTIASSSGEGITLDSTILKVSKSSEKSGFEKIPEQTALKFSDADVTG
TDSALSIVVAYPIYDDAGTLGYVAFIDVLNNDHTLVDSIKASTGDESTLFLENYRISTSVVSGNSRAVGTTASDVVYNTV
VKENTEFMGSANVVGQSFLTKYVPLKDSNGATIGMVFVGTPEAQFTQLVNNARNNTIIIALFGLLIAVVISLVSSRSITK
PINQLEDGVHKFGSGDYDHTINVKTGDELEELANSFNKMAKDIKELHSMLDADKLSLAKTLKEIFDIMDHLAEGDFSVRA
DENRHKNKLQKTINHAIENVSKMMENLKSEITVLSDELEDVGEGLKRAKETSEQVTDAANQVATAAADQSAKLQDTSDEL
EKTAKAADMVYNDAEQSVDSAIEVKDNSETGVKKVENAIDTMQKITNVIDELGKSIQELGEESKKINEVTVLIKDVAEQT
GLLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVEDINRTINGINKKVETTIDLGLAGRDEVDRGVVAIDEVNSA
FMKIKESVETSAKMIAQIKDNAKNASNNTQEALRNVQDIASISEEFAATAEELTASSEEQNRAVEEIDASAEKMMEISRK
LAEDADEFKTK

Specific function: Receptor For The Attractant L-Aspartate And Related Amino And Dicarboxylic Acids. Tar Also Mediates Taxis To The Attractant Maltose VIa An Interaction With The Periplasmic Maltose Binding Protein. Tar Mediates Taxis Away From The Repellents Cobalt And Ni

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=185, Percent_Identity=31.3513513513514, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787690, Length=198, Percent_Identity=31.3131313131313, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI2367378, Length=237, Percent_Identity=27.4261603375527, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788194, Length=279, Percent_Identity=27.5985663082437, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789453, Length=244, Percent_Identity=30.7377049180328, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 78812; Mature: 78812

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGTKKIGTKLLIFSIITVIIPIAILGIVSNNTITQDMKEQSADKLESSNEMANTIMDS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RFTELCTLAEYASYTQGVKTSIKTGNVDDLELRAETLKSASNADLVIFTGNGGSTIASSS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCEECCCC
GEGITLDSTILKVSKSSEKSGFEKIPEQTALKFSDADVTGTDSALSIVVAYPIYDDAGTL
CCCEEEHHHHHHHHCCCCHHHHHHCCHHHCCEECCCCCCCCCCCEEEEEEEEEECCCCHH
GYVAFIDVLNNDHTLVDSIKASTGDESTLFLENYRISTSVVSGNSRAVGTTASDVVYNTV
HHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHH
VKENTEFMGSANVVGQSFLTKYVPLKDSNGATIGMVFVGTPEAQFTQLVNNARNNTIIIA
HHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHHCCCCCEEHHH
LFGLLIAVVISLVSSRSITKPINQLEDGVHKFGSGDYDHTINVKTGDELEELANSFNKMA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHH
KDIKELHSMLDADKLSLAKTLKEIFDIMDHLAEGDFSVRADENRHKNKLQKTINHAIENV
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHH
SKMMENLKSEITVLSDELEDVGEGLKRAKETSEQVTDAANQVATAAADQSAKLQDTSDEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
EKTAKAADMVYNDAEQSVDSAIEVKDNSETGVKKVENAIDTMQKITNVIDELGKSIQELG
HHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EESKKINEVTVLIKDVAEQTGLLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVE
HHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DINRTINGINKKVETTIDLGLAGRDEVDRGVVAIDEVNSAFMKIKESVETSAKMIAQIKD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAKNASNNTQEALRNVQDIASISEEFAATAEELTASSEEQNRAVEEIDASAEKMMEISRK
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LAEDADEFKTK
HHHCHHHHCCC
>Mature Secondary Structure
MKLGTKKIGTKLLIFSIITVIIPIAILGIVSNNTITQDMKEQSADKLESSNEMANTIMDS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RFTELCTLAEYASYTQGVKTSIKTGNVDDLELRAETLKSASNADLVIFTGNGGSTIASSS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCEECCCC
GEGITLDSTILKVSKSSEKSGFEKIPEQTALKFSDADVTGTDSALSIVVAYPIYDDAGTL
CCCEEEHHHHHHHHCCCCHHHHHHCCHHHCCEECCCCCCCCCCCEEEEEEEEEECCCCHH
GYVAFIDVLNNDHTLVDSIKASTGDESTLFLENYRISTSVVSGNSRAVGTTASDVVYNTV
HHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHH
VKENTEFMGSANVVGQSFLTKYVPLKDSNGATIGMVFVGTPEAQFTQLVNNARNNTIIIA
HHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHHHHHHHHHCCCCCEEHHH
LFGLLIAVVISLVSSRSITKPINQLEDGVHKFGSGDYDHTINVKTGDELEELANSFNKMA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHH
KDIKELHSMLDADKLSLAKTLKEIFDIMDHLAEGDFSVRADENRHKNKLQKTINHAIENV
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHH
SKMMENLKSEITVLSDELEDVGEGLKRAKETSEQVTDAANQVATAAADQSAKLQDTSDEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
EKTAKAADMVYNDAEQSVDSAIEVKDNSETGVKKVENAIDTMQKITNVIDELGKSIQELG
HHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EESKKINEVTVLIKDVAEQTGLLALNASIEAARAGDAGKGFAVVASEIKSLAEEIKKSVE
HHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DINRTINGINKKVETTIDLGLAGRDEVDRGVVAIDEVNSAFMKIKESVETSAKMIAQIKD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAKNASNNTQEALRNVQDIASISEEFAATAEELTASSEEQNRAVEEIDASAEKMMEISRK
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LAEDADEFKTK
HHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]