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The map label for this gene is yleA [C]

Identifier: 45357975

GI number: 45357975

Start: 410405

End: 411682

Strand: Direct

Name: yleA [C]

Synonym: MMP0412

Alternate gene names: 45357975

Gene position: 410405-411682 (Clockwise)

Preceding gene: 45357973

Following gene: 45357976

Centisome position: 24.71

GC content: 32.47

Gene sequence:

>1278_bases
TTGAAAATTTACATTGAAGGATACGGCTGCACTTTAAACACTGCAGACACCCAAATAATAAAAAATTCAGTTAATGAATT
TGAAGATTTTGAATTGACCGATAATGTGGACGATTCTGACATAATTGTCATAAATACCTGTATTGTCAGGCAGGAAACCG
AACACAGAATGATTTCACGAATAGAATATTTCAAATCATTGGATAAAAAAGTTGTCGTAGCAGGATGCATGGCAAAAGCG
CTGTCTAAAAAAATTGAAAATCTTGCAGATGTTTTGATAATGCCAAGAGAAGCTCAGCATTCTGGAAACATCTTGAAAGA
TAAACTTTTAAAAGATTTTTCTGAAAAAAACAATGAATCAACTCAAAATTTAAATTTTGAAGACAAATTAAACGAAAAAA
TCAAAAAAGTAAGTTCACAAGGTTTAATTACCGCACTACCTATATGTGAAGGATGCCTTGGAAGCTGTACTTACTGCATA
GTAAAACGTGCAAGGGGAAATTTAGCGTCATACGATCGAGATTTAATTGTTAAAAAGGCAGAAGAACTTGTAAAATCAGG
TACAAAGTGCTTGCTTGTAACAGCACAGGACACTGCATGCTATGGGCTTGATAATAACGACAGCCTTCCAAATTTAATAA
ACGATATTTCAGAAATTCCTGAAAAATTTGCAATGAGAATTGGAATGATGCATGCAAAATTTGCAGAACCAATACTTGAC
GAATTAATTGAATCTTTTAAGTCCGAAAAAGTGGTAAAATTCCTCCACCTTCCAATTCAAAGTGGGGATGACCAGGTTTT
AAAAGATATGAACAGAAATTACACGGTTGATGAATATATTTCTGTATTAAATGAATTCAAGTCAAAAATTAAGAATTTAA
ACTTTACAACTGATGTAATCGTTGGATTTCCAACTGAAACAGAAGAAGCTTTTGAAAACACCCTTGAAATTGTAAAAAAG
ATAAAACCTGACTTTACACACGCTGCAAAATATTCTCAGAGAAAATACACAAAAGCAGCAATTTTAAAGCAAGTCGATAC
AAAAATAAGGAAAGAAAGATCTGAAATATTAAATGAATTAAGGCGAGAGTTAAGCTATGAAAATAATAAAAGACATATTG
GTGAAACTTTCGAAATACTTGTAACCAAGGATAATATGGGCGTTACTGACAACTGTAAAAACGTGATTTTCGAAGAACCT
GCAAAAATCGGTGAGTTTAAGCGAGTTAAAATAACTGGTGCAAAGACTTTCGGACTTTCGGGTAAACTGATAAATTAA

Upstream 100 bases:

>100_bases
AACACTCGTTACAAAATCAACCCCTGAATCTAGTATTGCTTTATAAACAGCTTCACTTGCATTCATAACTCCACCATCCG
GCTTTATTTTGGTGATAAAA

Downstream 100 bases:

>100_bases
TCTCTTTTTTTTCGATTTTATTTAGCATATTTTTTACATTTTTAATTCCTTTTTCAACCTTAAATCGGTGTACCTACACA
AAGACCCACATAAAAACAAT

Product: MiaB-like tRNA modifying protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKIYIEGYGCTLNTADTQIIKNSVNEFEDFELTDNVDDSDIIVINTCIVRQETEHRMISRIEYFKSLDKKVVVAGCMAKA
LSKKIENLADVLIMPREAQHSGNILKDKLLKDFSEKNNESTQNLNFEDKLNEKIKKVSSQGLITALPICEGCLGSCTYCI
VKRARGNLASYDRDLIVKKAEELVKSGTKCLLVTAQDTACYGLDNNDSLPNLINDISEIPEKFAMRIGMMHAKFAEPILD
ELIESFKSEKVVKFLHLPIQSGDDQVLKDMNRNYTVDEYISVLNEFKSKIKNLNFTTDVIVGFPTETEEAFENTLEIVKK
IKPDFTHAAKYSQRKYTKAAILKQVDTKIRKERSEILNELRRELSYENNKRHIGETFEILVTKDNMGVTDNCKNVIFEEP
AKIGEFKRVKITGAKTFGLSGKLIN

Sequences:

>Translated_425_residues
MKIYIEGYGCTLNTADTQIIKNSVNEFEDFELTDNVDDSDIIVINTCIVRQETEHRMISRIEYFKSLDKKVVVAGCMAKA
LSKKIENLADVLIMPREAQHSGNILKDKLLKDFSEKNNESTQNLNFEDKLNEKIKKVSSQGLITALPICEGCLGSCTYCI
VKRARGNLASYDRDLIVKKAEELVKSGTKCLLVTAQDTACYGLDNNDSLPNLINDISEIPEKFAMRIGMMHAKFAEPILD
ELIESFKSEKVVKFLHLPIQSGDDQVLKDMNRNYTVDEYISVLNEFKSKIKNLNFTTDVIVGFPTETEEAFENTLEIVKK
IKPDFTHAAKYSQRKYTKAAILKQVDTKIRKERSEILNELRRELSYENNKRHIGETFEILVTKDNMGVTDNCKNVIFEEP
AKIGEFKRVKITGAKTFGLSGKLIN
>Mature_425_residues
MKIYIEGYGCTLNTADTQIIKNSVNEFEDFELTDNVDDSDIIVINTCIVRQETEHRMISRIEYFKSLDKKVVVAGCMAKA
LSKKIENLADVLIMPREAQHSGNILKDKLLKDFSEKNNESTQNLNFEDKLNEKIKKVSSQGLITALPICEGCLGSCTYCI
VKRARGNLASYDRDLIVKKAEELVKSGTKCLLVTAQDTACYGLDNNDSLPNLINDISEIPEKFAMRIGMMHAKFAEPILD
ELIESFKSEKVVKFLHLPIQSGDDQVLKDMNRNYTVDEYISVLNEFKSKIKNLNFTTDVIVGFPTETEEAFENTLEIVKK
IKPDFTHAAKYSQRKYTKAAILKQVDTKIRKERSEILNELRRELSYENNKRHIGETFEILVTKDNMGVTDNCKNVIFEEP
AKIGEFKRVKITGAKTFGLSGKLIN

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=394, Percent_Identity=30.2030456852792, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI28872782, Length=486, Percent_Identity=24.8971193415638, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI28872784, Length=486, Percent_Identity=24.8971193415638, Blast_Score=138, Evalue=8e-33,
Organism=Escherichia coli, GI1786882, Length=445, Percent_Identity=27.6404494382022, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1787057, Length=451, Percent_Identity=25.9423503325942, Blast_Score=141, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71996771, Length=298, Percent_Identity=33.5570469798658, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17553146, Length=473, Percent_Identity=24.5243128964059, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI19922432, Length=443, Percent_Identity=28.6681715575621, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI21356207, Length=427, Percent_Identity=25.2927400468384, Blast_Score=135, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 48286; Mature: 48286

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYIEGYGCTLNTADTQIIKNSVNEFEDFELTDNVDDSDIIVINTCIVRQETEHRMISR
CEEEEEEECCEECCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHH
IEYFKSLDKKVVVAGCMAKALSKKIENLADVLIMPREAQHSGNILKDKLLKDFSEKNNES
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCC
TQNLNFEDKLNEKIKKVSSQGLITALPICEGCLGSCTYCIVKRARGNLASYDRDLIVKKA
CCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EELVKSGTKCLLVTAQDTACYGLDNNDSLPNLINDISEIPEKFAMRIGMMHAKFAEPILD
HHHHHCCCEEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELIESFKSEKVVKFLHLPIQSGDDQVLKDMNRNYTVDEYISVLNEFKSKIKNLNFTTDVI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
VGFPTETEEAFENTLEIVKKIKPDFTHAAKYSQRKYTKAAILKQVDTKIRKERSEILNEL
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRELSYENNKRHIGETFEILVTKDNMGVTDNCKNVIFEEPAKIGEFKRVKITGAKTFGLS
HHHHCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHCCCHHCCCEEEEEEECCEEECCC
GKLIN
CCCCC
>Mature Secondary Structure
MKIYIEGYGCTLNTADTQIIKNSVNEFEDFELTDNVDDSDIIVINTCIVRQETEHRMISR
CEEEEEEECCEECCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHH
IEYFKSLDKKVVVAGCMAKALSKKIENLADVLIMPREAQHSGNILKDKLLKDFSEKNNES
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCC
TQNLNFEDKLNEKIKKVSSQGLITALPICEGCLGSCTYCIVKRARGNLASYDRDLIVKKA
CCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
EELVKSGTKCLLVTAQDTACYGLDNNDSLPNLINDISEIPEKFAMRIGMMHAKFAEPILD
HHHHHCCCEEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELIESFKSEKVVKFLHLPIQSGDDQVLKDMNRNYTVDEYISVLNEFKSKIKNLNFTTDVI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEE
VGFPTETEEAFENTLEIVKKIKPDFTHAAKYSQRKYTKAAILKQVDTKIRKERSEILNEL
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRELSYENNKRHIGETFEILVTKDNMGVTDNCKNVIFEEPAKIGEFKRVKITGAKTFGLS
HHHHCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHCCCHHCCCEEEEEEECCEEECCC
GKLIN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]