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The map label for this gene is cbiC [H]

Identifier: 45357893

GI number: 45357893

Start: 327278

End: 327910

Strand: Direct

Name: cbiC [H]

Synonym: MMP0330

Alternate gene names: 45357893

Gene position: 327278-327910 (Clockwise)

Preceding gene: 45357892

Following gene: 45357895

Centisome position: 19.7

GC content: 36.18

Gene sequence:

>633_bases
ATGGGAGCAGTAACCAAGGATGGAAAAGAAATCGCAGACCGATCAAGAGAAATAGTAAAAACAAAAATAAGCGAAGTTTT
GGGAAAAAATGTTGTATTATACTCTAAGGACGAAATGGGAATAATTGAAAGAGTAGTTCATGCAACTGCCGATCCAGAGT
ATTCAAAACTCGTTAATTTTGATAACAAACCAATTGAACATGGTTTAAAAGCAATAAATGATGAAAGTCCGATAATTGCA
GATATTTCGATGGTAAAAGCAGGAATACGCTATGAAGACGTATTATGCACAATTTCCGAAAAGAAAGTCTTCGAAGTTGC
AAAAAAAGAGCAAGTTACAAGGGCAGTTGCATCAATTCGGGCTTCAAAAGAGTTAATCGACGGCGGTATTGTTGTTATTG
GCAATGCACCGACAGCACTTCTTGAAGTCATAAGATTGAATAAAAAAGAAGGAATAACTCCTAAATTAGTTATAGGGGCC
CCAGTTGGTTTTGTAAAGGCAGCAGAATCAAAAGAATTATTAAGAACGACAAAAATCCCGTCAATTTCTACAATTGGTCC
AAAAGGGGGAACTCCTGTCGCAGTTTCAGCAATTAACGGAATCATTGCGCTTAGTAAAAATGAAAGAATTTAA

Upstream 100 bases:

>100_bases
ATATTGAGAATATTTCAAGGGATGTTTTAGAAGTAGCGCACATTCCTGAAAACAGCAATAAAAAAATCATACTTTCAGTT
CTTTAAGTGATAACATGTTT

Downstream 100 bases:

>100_bases
ATTATTCCATTATTCTATCGTAAATTGAATCAAGGTCAACGTTTATCGGGTCTTTTAACACATAAACTGGGTAACCTTCG
TTTTCATATCTTGGGATGAT

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MGAVTKDGKEIADRSREIVKTKISEVLGKNVVLYSKDEMGIIERVVHATADPEYSKLVNFDNKPIEHGLKAINDESPIIA
DISMVKAGIRYEDVLCTISEKKVFEVAKKEQVTRAVASIRASKELIDGGIVVIGNAPTALLEVIRLNKKEGITPKLVIGA
PVGFVKAAESKELLRTTKIPSISTIGPKGGTPVAVSAINGIIALSKNERI

Sequences:

>Translated_210_residues
MGAVTKDGKEIADRSREIVKTKISEVLGKNVVLYSKDEMGIIERVVHATADPEYSKLVNFDNKPIEHGLKAINDESPIIA
DISMVKAGIRYEDVLCTISEKKVFEVAKKEQVTRAVASIRASKELIDGGIVVIGNAPTALLEVIRLNKKEGITPKLVIGA
PVGFVKAAESKELLRTTKIPSISTIGPKGGTPVAVSAINGIIALSKNERI
>Mature_209_residues
GAVTKDGKEIADRSREIVKTKISEVLGKNVVLYSKDEMGIIERVVHATADPEYSKLVNFDNKPIEHGLKAINDESPIIAD
ISMVKAGIRYEDVLCTISEKKVFEVAKKEQVTRAVASIRASKELIDGGIVVIGNAPTALLEVIRLNKKEGITPKLVIGAP
VGFVKAAESKELLRTTKIPSISTIGPKGGTPVAVSAINGIIALSKNERI

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 22538; Mature: 22406

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAVTKDGKEIADRSREIVKTKISEVLGKNVVLYSKDEMGIIERVVHATADPEYSKLVNF
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHCC
DNKPIEHGLKAINDESPIIADISMVKAGIRYEDVLCTISEKKVFEVAKKEQVTRAVASIR
CCCCHHHHHHHCCCCCCEEHHHHHHHHCCCEEHEEEECCHHHHHHHHHHHHHHHHHHHHH
ASKELIDGGIVVIGNAPTALLEVIRLNKKEGITPKLVIGAPVGFVKAAESKELLRTTKIP
HHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCC
SISTIGPKGGTPVAVSAINGIIALSKNERI
CCEECCCCCCCCEEEEECCCEEEECCCCCC
>Mature Secondary Structure 
GAVTKDGKEIADRSREIVKTKISEVLGKNVVLYSKDEMGIIERVVHATADPEYSKLVNF
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHCC
DNKPIEHGLKAINDESPIIADISMVKAGIRYEDVLCTISEKKVFEVAKKEQVTRAVASIR
CCCCHHHHHHHCCCCCCEEHHHHHHHHCCCEEHEEEECCHHHHHHHHHHHHHHHHHHHHH
ASKELIDGGIVVIGNAPTALLEVIRLNKKEGITPKLVIGAPVGFVKAAESKELLRTTKIP
HHHHHHCCCEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCC
SISTIGPKGGTPVAVSAINGIIALSKNERI
CCEECCCCCCCCEEEEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]