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The map label for this gene is 45357643

Identifier: 45357643

GI number: 45357643

Start: 90509

End: 91600

Strand: Direct

Name: 45357643

Synonym: MMP0080

Alternate gene names: NA

Gene position: 90509-91600 (Clockwise)

Preceding gene: 45357642

Following gene: 45357644

Centisome position: 5.45

GC content: 38.19

Gene sequence:

>1092_bases
ATGTGCGGAATTATCGGATTTATGAGTAGAACTGGAAGACTTATCAGTGGAGACAGGATTGCTACAGCCTTGAATTGTTT
AAAGGAAAGAGGAAATGGTGAAGGTTCAGGTTATGTAGGATATGGAATCTACCCAGACTATAAAGATGACTATGCAATAC
ACGTTTTTTTAGATGCAACCAAAGATTACGATAAAATTAGACACGAAGTCGAAGAAGTTCTTGTAAAATACGGATACATC
TTAAAAGATGAAGAAATTCCAACAGAAGAAGGAATTATCAAAAAAGAACAGGTTTCGTGGAGATTTTTCTACAGGTTTGA
TGAAAAATATAAATCAGTCGAAGAAGACATGATGGTGGATATCGTAATGGATATCAACGCTAAAATCGACGGAGCATTTG
TATTTTCAAGCGGTAAAAATATGGGCGTATTTAAAGCTGCTGCATGGCCATTAGAAGTTGCAGAATACTTTAAAATTGAC
CAGTACAAAGGTTTCCAATGGCTTTCACATGCAAGATACCCTACAAACACGAAAGGATGGTGGGGAGGTGCGCACCCATT
CAACCTGTTAGGATGGTCCGTAGTTCACAACGGAGAAATTACAAGCTACGGTGCAAACAAAAGATACGTTGAAAGTTTTG
GATACAAATGTAAACTTTTAACCGACACGGAAGTTGTTGCATATCTCTTCGATTTACTCATCAGGAAACACAAAATCCCT
GTAGAATATGCAATGAGTGCATTAGCTCCAAGATTCTGGGACGAAATCGAGAGCATGTCTGAGGAAGATAAAAAAATACA
CGAAGCAATCCGTATGACCTATGGCGGTGCAACAATGAACGGTCCTTTCGGAATTGTTGTTGGAACACAAGAAGGAATGG
CTTTCATGAACGGCGAAGTCGAAGAAGGAAATACTATGGTTGGCTTAACCGATAGAATTAAATTAAGACCATTAGTTGCG
GCAGAAAAAGACGACTTGTTATTTGTATCAAGTGAAGAATCAGCAATTAGGAAAATATGCCCTGAATTGGATCGAGTATG
GATGCCAGACGCAGGAAGAATGGTTATTGCAAAATTAGAGAAAAAAATTTAA

Upstream 100 bases:

>100_bases
ATAACAAATAATTTTTCAGAGTATTTTGGCTCTTTTATATTCAATAATGTATATAAATGACTTTTTTCATAATAGGATAA
CCTAAAGTTGGAGGCTTATC

Downstream 100 bases:

>100_bases
TTTAAGTTAATAATTAGGTGAGAAAAGATGATACCTTCAACAGTTCCGCCAAAATACAAAGTTTTTGTGGATCCGGAAAG
ATGTATGCTTTGTGAACGAT

Product: glutamate synthase large subunit

Products: L-glutamine; 2-oxoglutarate; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MCGIIGFMSRTGRLISGDRIATALNCLKERGNGEGSGYVGYGIYPDYKDDYAIHVFLDATKDYDKIRHEVEEVLVKYGYI
LKDEEIPTEEGIIKKEQVSWRFFYRFDEKYKSVEEDMMVDIVMDINAKIDGAFVFSSGKNMGVFKAAAWPLEVAEYFKID
QYKGFQWLSHARYPTNTKGWWGGAHPFNLLGWSVVHNGEITSYGANKRYVESFGYKCKLLTDTEVVAYLFDLLIRKHKIP
VEYAMSALAPRFWDEIESMSEEDKKIHEAIRMTYGGATMNGPFGIVVGTQEGMAFMNGEVEEGNTMVGLTDRIKLRPLVA
AEKDDLLFVSSEESAIRKICPELDRVWMPDAGRMVIAKLEKKI

Sequences:

>Translated_363_residues
MCGIIGFMSRTGRLISGDRIATALNCLKERGNGEGSGYVGYGIYPDYKDDYAIHVFLDATKDYDKIRHEVEEVLVKYGYI
LKDEEIPTEEGIIKKEQVSWRFFYRFDEKYKSVEEDMMVDIVMDINAKIDGAFVFSSGKNMGVFKAAAWPLEVAEYFKID
QYKGFQWLSHARYPTNTKGWWGGAHPFNLLGWSVVHNGEITSYGANKRYVESFGYKCKLLTDTEVVAYLFDLLIRKHKIP
VEYAMSALAPRFWDEIESMSEEDKKIHEAIRMTYGGATMNGPFGIVVGTQEGMAFMNGEVEEGNTMVGLTDRIKLRPLVA
AEKDDLLFVSSEESAIRKICPELDRVWMPDAGRMVIAKLEKKI
>Mature_363_residues
MCGIIGFMSRTGRLISGDRIATALNCLKERGNGEGSGYVGYGIYPDYKDDYAIHVFLDATKDYDKIRHEVEEVLVKYGYI
LKDEEIPTEEGIIKKEQVSWRFFYRFDEKYKSVEEDMMVDIVMDINAKIDGAFVFSSGKNMGVFKAAAWPLEVAEYFKID
QYKGFQWLSHARYPTNTKGWWGGAHPFNLLGWSVVHNGEITSYGANKRYVESFGYKCKLLTDTEVVAYLFDLLIRKHKIP
VEYAMSALAPRFWDEIESMSEEDKKIHEAIRMTYGGATMNGPFGIVVGTQEGMAFMNGEVEEGNTMVGLTDRIKLRPLVA
AEKDDLLFVSSEESAIRKICPELDRVWMPDAGRMVIAKLEKKI

Specific function: Unknown

COG id: COG0067

COG function: function code E; Glutamate synthase domain 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR012375 [H]

Pfam domain/function: PF00310 GATase_2 [H]

EC number: 1.4.1.13

Molecular weight: Translated: 41358; Mature: 41358

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIIGFMSRTGRLISGDRIATALNCLKERGNGEGSGYVGYGIYPDYKDDYAIHVFLDAT
CCCCHHHHHHCCCEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEECC
KDYDKIRHEVEEVLVKYGYILKDEEIPTEEGIIKKEQVSWRFFYRFDEKYKSVEEDMMVD
CCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEHHHCCEEEEEEECHHHHHHHHHHEEE
IVMDINAKIDGAFVFSSGKNMGVFKAAAWPLEVAEYFKIDQYKGFQWLSHARYPTNTKGW
EEEECCCEECEEEEEECCCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCC
WGGAHPFNLLGWSVVHNGEITSYGANKRYVESFGYKCKLLTDTEVVAYLFDLLIRKHKIP
CCCCCCHHHEEEEEEECCEEEEECCCCHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCC
VEYAMSALAPRFWDEIESMSEEDKKIHEAIRMTYGGATMNGPFGIVVGTQEGMAFMNGEV
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCCEEECCEE
EEGNTMVGLTDRIKLRPLVAAEKDDLLFVSSEESAIRKICPELDRVWMPDAGRMVIAKLE
CCCCEEEEECCCEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
KKI
HCC
>Mature Secondary Structure
MCGIIGFMSRTGRLISGDRIATALNCLKERGNGEGSGYVGYGIYPDYKDDYAIHVFLDAT
CCCCHHHHHHCCCEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEECC
KDYDKIRHEVEEVLVKYGYILKDEEIPTEEGIIKKEQVSWRFFYRFDEKYKSVEEDMMVD
CCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCEEHHHCCEEEEEEECHHHHHHHHHHEEE
IVMDINAKIDGAFVFSSGKNMGVFKAAAWPLEVAEYFKIDQYKGFQWLSHARYPTNTKGW
EEEECCCEECEEEEEECCCCCCEEEECCCHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCC
WGGAHPFNLLGWSVVHNGEITSYGANKRYVESFGYKCKLLTDTEVVAYLFDLLIRKHKIP
CCCCCCHHHEEEEEEECCEEEEECCCCHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCC
VEYAMSALAPRFWDEIESMSEEDKKIHEAIRMTYGGATMNGPFGIVVGTQEGMAFMNGEV
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCCEEECCEE
EEGNTMVGLTDRIKLRPLVAAEKDDLLFVSSEESAIRKICPELDRVWMPDAGRMVIAKLE
CCCCEEEEECCCEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
KKI
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-glutamate; NADP+

Specific reaction: 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]