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The map label for this gene is gltB [C]

Identifier: 45357644

GI number: 45357644

Start: 91628

End: 93160

Strand: Direct

Name: gltB [C]

Synonym: MMP0081

Alternate gene names: 45357644

Gene position: 91628-93160 (Clockwise)

Preceding gene: 45357643

Following gene: 45357645

Centisome position: 5.52

GC content: 39.92

Gene sequence:

>1533_bases
ATGATACCTTCAACAGTTCCGCCAAAATACAAAGTTTTTGTGGATCCGGAAAGATGTATGCTTTGTGAACGATGTACTAC
TGAATGTTCATGGGGCGTTTACAGAAGACAGGGAAATAAAATTTTAACTTACCCTAACAGATGTGGGGCATGTTTAAGAT
GCGTTTCACTGTGCCCTAGAGATGCTATTACAGTTACATTAAATCAATCATGCGGTAGGGAACACCCTGTATGGACACCT
GAAGTAAAACAGGATGTTGTAACACAGGCGAAATCAGGATGTATTCTATTAAGTGGTATGGGTAATGCAAAAGAGTACCC
AATATACTTCGATAAAATTGTTCTTGATGCATGTCAGGTAACGAACCCTTCAATAGATCCATTGAGAGAACCTATGGAAC
TCAGGACCTACGTTGGTAAAAAACCAGAAAAATTAGAATTTGACTACGTTGAAGATGAAATCGACGGTAAAAAGGTCAAA
AAAGCAAAATTAAAAACAAAAATTGCTCCAAATCTTAAGTTAGATACTCCAATAATGATTGGACACATGTCTTACGGTGC
TCTTTCATTAAACGCTCACAAAGCAATGGCAAAAGCTGTAAAAGAATGTGGAACGTTCATGGGAACCGGTGAAGGTGGAC
TTCACAGGGATTTGTACGGATATTCCGATAATGTAATTACCCAAGTTGCAAGCGGTAGATTTGGTGTAAATAGCGAATAT
TTAAACAAAGGAGCTGCAATTGAAATCAAAATCGGTCAAGGTGCAAAACCTGGAATCGGAGGACACTTACCTGGAGAAAA
AGTGTCAGCAGAAGTTTCAATGACAAGAATGATTCCGCAAGGGTCAGACGCAATTTCACCAGCACCTCACCACGATATTT
ACTCAATTGAAGATCTTGCACAGCTTATCAGAAGTTTGAAAGAAGCTACAAGATGGAAAATGCCAGTATTTGTTAAAATT
TCTGCAGTACACAATGTATCCGCAATTGCAAACGGTATTGCAACATCAGATGCAGACGCAGTTGTTATTGATGGATTTAA
AGGAGGAACTGGTGCTGCACCTAAAGTATTCAGGGATAATGTTGGTATTCCAATCGAAGTTGCAATTGCAGCAGTAGATG
ACAGGCTCAGAGAGCAAGGAAACAGGCATAAAATAAGCATCATTGCAAGTGGGGGTATTAGAAACTCCGCCGATGTATTT
AAGTCAATTGCACTTGGTGCTGATGCAGTATACATTGGAACTGCCGCAATGGTTGCAATGGGATGTACTGTATGTGGAAG
ATGCTACACAGGACAGTGTGCATGGGGTATTGCAACTCAGAAACCTGAACTCGTAAAAAGATTGGAAGTAGATGACGCTG
CAAGAAGAGTCGCTAATTTAATACATGCATGGACTCACGAAATTCAAGAATTACTCGGAGCTGCAGGAATCAACTCTATA
GAAAGTCTCAGAGGAAACAGAGACAGGTTAAGAGGCGTAGGACTCAGCGAGATTGAATTAAATACATTAGGAATAAAACA
GGCAGGAATGTAA

Upstream 100 bases:

>100_bases
CCCTGAATTGGATCGAGTATGGATGCCAGACGCAGGAAGAATGGTTATTGCAAAATTAGAGAAAAAAATTTAATTTAAGT
TAATAATTAGGTGAGAAAAG

Downstream 100 bases:

>100_bases
TGGCCAGTCTAGGTGAAAGAATGAAAGAACTTAAAATTGACGCCAAGGACATGGACTACAGGGAATTAAACGAGAAAATC
CACGAAGTTTTGGACGAAAA

Product: glutamate synthase large subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MIPSTVPPKYKVFVDPERCMLCERCTTECSWGVYRRQGNKILTYPNRCGACLRCVSLCPRDAITVTLNQSCGREHPVWTP
EVKQDVVTQAKSGCILLSGMGNAKEYPIYFDKIVLDACQVTNPSIDPLREPMELRTYVGKKPEKLEFDYVEDEIDGKKVK
KAKLKTKIAPNLKLDTPIMIGHMSYGALSLNAHKAMAKAVKECGTFMGTGEGGLHRDLYGYSDNVITQVASGRFGVNSEY
LNKGAAIEIKIGQGAKPGIGGHLPGEKVSAEVSMTRMIPQGSDAISPAPHHDIYSIEDLAQLIRSLKEATRWKMPVFVKI
SAVHNVSAIANGIATSDADAVVIDGFKGGTGAAPKVFRDNVGIPIEVAIAAVDDRLREQGNRHKISIIASGGIRNSADVF
KSIALGADAVYIGTAAMVAMGCTVCGRCYTGQCAWGIATQKPELVKRLEVDDAARRVANLIHAWTHEIQELLGAAGINSI
ESLRGNRDRLRGVGLSEIELNTLGIKQAGM

Sequences:

>Translated_510_residues
MIPSTVPPKYKVFVDPERCMLCERCTTECSWGVYRRQGNKILTYPNRCGACLRCVSLCPRDAITVTLNQSCGREHPVWTP
EVKQDVVTQAKSGCILLSGMGNAKEYPIYFDKIVLDACQVTNPSIDPLREPMELRTYVGKKPEKLEFDYVEDEIDGKKVK
KAKLKTKIAPNLKLDTPIMIGHMSYGALSLNAHKAMAKAVKECGTFMGTGEGGLHRDLYGYSDNVITQVASGRFGVNSEY
LNKGAAIEIKIGQGAKPGIGGHLPGEKVSAEVSMTRMIPQGSDAISPAPHHDIYSIEDLAQLIRSLKEATRWKMPVFVKI
SAVHNVSAIANGIATSDADAVVIDGFKGGTGAAPKVFRDNVGIPIEVAIAAVDDRLREQGNRHKISIIASGGIRNSADVF
KSIALGADAVYIGTAAMVAMGCTVCGRCYTGQCAWGIATQKPELVKRLEVDDAARRVANLIHAWTHEIQELLGAAGINSI
ESLRGNRDRLRGVGLSEIELNTLGIKQAGM
>Mature_510_residues
MIPSTVPPKYKVFVDPERCMLCERCTTECSWGVYRRQGNKILTYPNRCGACLRCVSLCPRDAITVTLNQSCGREHPVWTP
EVKQDVVTQAKSGCILLSGMGNAKEYPIYFDKIVLDACQVTNPSIDPLREPMELRTYVGKKPEKLEFDYVEDEIDGKKVK
KAKLKTKIAPNLKLDTPIMIGHMSYGALSLNAHKAMAKAVKECGTFMGTGEGGLHRDLYGYSDNVITQVASGRFGVNSEY
LNKGAAIEIKIGQGAKPGIGGHLPGEKVSAEVSMTRMIPQGSDAISPAPHHDIYSIEDLAQLIRSLKEATRWKMPVFVKI
SAVHNVSAIANGIATSDADAVVIDGFKGGTGAAPKVFRDNVGIPIEVAIAAVDDRLREQGNRHKISIIASGGIRNSADVF
KSIALGADAVYIGTAAMVAMGCTVCGRCYTGQCAWGIATQKPELVKRLEVDDAARRVANLIHAWTHEIQELLGAAGINSI
ESLRGNRDRLRGVGLSEIELNTLGIKQAGM

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=310, Percent_Identity=41.2903225806452, Blast_Score=201, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17570289, Length=346, Percent_Identity=36.4161849710983, Blast_Score=204, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6320030, Length=317, Percent_Identity=36.9085173501577, Blast_Score=204, Evalue=3e-53,
Organism=Drosophila melanogaster, GI28574881, Length=347, Percent_Identity=36.5994236311239, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24665539, Length=347, Percent_Identity=36.5994236311239, Blast_Score=202, Evalue=6e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013785
- InterPro:   IPR002932 [H]

Pfam domain/function: PF01645 Glu_synthase [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 55153; Mature: 55153

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPSTVPPKYKVFVDPERCMLCERCTTECSWGVYRRQGNKILTYPNRCGACLRCVSLCPR
CCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCHHHHCCCEEEECCCHHHHHHHHHHHCCC
DAITVTLNQSCGREHPVWTPEVKQDVVTQAKSGCILLSGMGNAKEYPIYFDKIVLDACQV
CCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEHHHHHHHHHHC
TNPSIDPLREPMELRTYVGKKPEKLEFDYVEDEIDGKKVKKAKLKTKIAPNLKLDTPIMI
CCCCHHHHHCHHHHHHHHCCCCCCEECCCHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEE
GHMSYGALSLNAHKAMAKAVKECGTFMGTGEGGLHRDLYGYSDNVITQVASGRFGVNSEY
EECCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHH
LNKGAAIEIKIGQGAKPGIGGHLPGEKVSAEVSMTRMIPQGSDAISPAPHHDIYSIEDLA
HCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
QLIRSLKEATRWKMPVFVKISAVHNVSAIANGIATSDADAVVIDGFKGGTGAAPKVFRDN
HHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHCC
VGIPIEVAIAAVDDRLREQGNRHKISIIASGGIRNSADVFKSIALGADAVYIGTAAMVAM
CCCCEEEEEEHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEHHHHHHHHH
GCTVCGRCYTGQCAWGIATQKPELVKRLEVDDAARRVANLIHAWTHEIQELLGAAGINSI
HHHHHCCCCCCCEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ESLRGNRDRLRGVGLSEIELNTLGIKQAGM
HHHCCCHHHHCCCCCCEEEEEEECCHHCCC
>Mature Secondary Structure
MIPSTVPPKYKVFVDPERCMLCERCTTECSWGVYRRQGNKILTYPNRCGACLRCVSLCPR
CCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCHHHHCCCEEEECCCHHHHHHHHHHHCCC
DAITVTLNQSCGREHPVWTPEVKQDVVTQAKSGCILLSGMGNAKEYPIYFDKIVLDACQV
CCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEHHHHHHHHHHC
TNPSIDPLREPMELRTYVGKKPEKLEFDYVEDEIDGKKVKKAKLKTKIAPNLKLDTPIMI
CCCCHHHHHCHHHHHHHHCCCCCCEECCCHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEE
GHMSYGALSLNAHKAMAKAVKECGTFMGTGEGGLHRDLYGYSDNVITQVASGRFGVNSEY
EECCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHH
LNKGAAIEIKIGQGAKPGIGGHLPGEKVSAEVSMTRMIPQGSDAISPAPHHDIYSIEDLA
HCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
QLIRSLKEATRWKMPVFVKISAVHNVSAIANGIATSDADAVVIDGFKGGTGAAPKVFRDN
HHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHCC
VGIPIEVAIAAVDDRLREQGNRHKISIIASGGIRNSADVFKSIALGADAVYIGTAAMVAM
CCCCEEEEEEHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEHHHHHHHHH
GCTVCGRCYTGQCAWGIATQKPELVKRLEVDDAARRVANLIHAWTHEIQELLGAAGINSI
HHHHHCCCCCCCEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ESLRGNRDRLRGVGLSEIELNTLGIKQAGM
HHHCCCHHHHCCCCCCEEEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]