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The map label for this gene is hisE [H]

Identifier: 45357614

GI number: 45357614

Start: 66822

End: 67112

Strand: Direct

Name: hisE [H]

Synonym: MMP0051

Alternate gene names: 45357614

Gene position: 66822-67112 (Clockwise)

Preceding gene: 45357613

Following gene: 45357621

Centisome position: 4.02

GC content: 32.65

Gene sequence:

>291_bases
ATGAATGTTTTAAAAGAAGTATATGCTACGATCGAAAAAAGAATCGAAGAAAAACCCGAAGGCTCTTACGTTGCTAAATT
AACAACGGATGACAAAAAAACTGCAGTAAATAAAATCTGCGAAAAAGTCGGTGAAGAAGCTGCAGAAGTTATTATTGCAG
CAAAAGACAACGATAAAGCAGAAATAATTTACGAAAGCGCGGATTTAATTTTTCATACAATGGTCCTTCTTGCAAAATCA
GGAATTACCTATGAAGAATTAAGCGAAGAATTCAAGAAAAGAATGAAATAA

Upstream 100 bases:

>100_bases
TACGGTAAAAACGCAGTAGAAGCTGCTGTTAAAATGGTAAAAAGACTTAAAGAAATTCAATAATTTAAAATTAAATTTAT
AAATCTTTTTTAGTGATTTT

Downstream 100 bases:

>100_bases
CTTATTTTAAATACTTTTTTAGAATTTTTGGAAAGATTGTACCTTCAATTAGATTCAGAATATCTGTTCTTGTAAGAATT
CCAATTGCGATTTCTTCGTT

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH [H]

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MNVLKEVYATIEKRIEEKPEGSYVAKLTTDDKKTAVNKICEKVGEEAAEVIIAAKDNDKAEIIYESADLIFHTMVLLAKS
GITYEELSEEFKKRMK

Sequences:

>Translated_96_residues
MNVLKEVYATIEKRIEEKPEGSYVAKLTTDDKKTAVNKICEKVGEEAAEVIIAAKDNDKAEIIYESADLIFHTMVLLAKS
GITYEELSEEFKKRMK
>Mature_96_residues
MNVLKEVYATIEKRIEEKPEGSYVAKLTTDDKKTAVNKICEKVGEEAAEVIIAAKDNDKAEIIYESADLIFHTMVLLAKS
GITYEELSEEFKKRMK

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008179
- InterPro:   IPR021130 [H]

Pfam domain/function: PF01503 PRA-PH [H]

EC number: =3.6.1.31 [H]

Molecular weight: Translated: 10886; Mature: 10886

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLKEVYATIEKRIEEKPEGSYVAKLTTDDKKTAVNKICEKVGEEAAEVIIAAKDNDKA
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHEEEECCCCCCH
EIIYESADLIFHTMVLLAKSGITYEELSEEFKKRMK
HEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNVLKEVYATIEKRIEEKPEGSYVAKLTTDDKKTAVNKICEKVGEEAAEVIIAAKDNDKA
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHEEEECCCCCCH
EIIYESADLIFHTMVLLAKSGITYEELSEEFKKRMK
HEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA