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The map label for this gene is mer [H]

Identifier: 45357621

GI number: 45357621

Start: 72602

End: 73564

Strand: Direct

Name: mer [H]

Synonym: MMP0058

Alternate gene names: 45357621

Gene position: 72602-73564 (Clockwise)

Preceding gene: 45357614

Following gene: 45357626

Centisome position: 4.37

GC content: 40.29

Gene sequence:

>963_bases
ATGAAATTTGGTATCGAATTTGTTCCAAACGAACCAATAACCAAACTAGCATACTACGTTAAATTAGCAGAAGACAACGG
ATTTGAATTCTGCTGGATTACAGACCACTACAATAACAGAAACGTATACATGACCTTAGGAAACCTTGCAGCAGCAACAA
ACAAAATTAAATTAGGTCCTGGTGTTACAAACCCATACGTAAGAAGCCCTGCAATCGCAGCATCCGCAATGGCTACAGTA
GACGAATTATCAGGCGGTAGAGCTACATTTGGTATCGGCCCTGGTGACAAAGCAACATTTGATGCATTAGGTATTGAATG
GACAAAACCTGTCGGAACCATCAAAAAAGCAATCGCAGACTTTAAAGAATTAACCGCTGGAAAAAGAATGGCAGAAGGTG
CACAACTTGCAGTTAAACCTTCAGCAAAAATTCCAATTTACATGGGAGCACAAGGCCCTAAAATGTTAGAAACCGCAGGA
GAAATTGCCGACGGTGTTTTAATCAACGCTTCAAACCCAAAAGACTTCGAAGCAGCAGTTCCTTTAATTAAAAAAGGAGC
AGAAGCAGCAGGAAGAAGCATGTCAGAAATTGACGTTGCAGCATACGCATGCATGTCAGTAGACAAAAAAGCAGAAAAAG
CTAAACAAGCAGCAATCCCAGTTGTAGCATTCATCGCTGCTGGTTCACCTCCTATGATCTTAGAAAGACATGGAATCGAC
CCTGCTAAAGTTGATGCAATCAGAGCAGGATTGAAAGAAGGAAACTTCGGTGCAGCATTCGGAAATGTTGACGAAAACAT
GTTAGAAGGATTTGCTTTATACGGTACACCTGAAGAAGTTGTAGAAAAAGTAAAAGCATTAGAAAAAATGGGTGTAACCC
AAGTTGTTGCTGGATCCCCAATCGGACCAAACAAAGACACCAGCATCAAATTAATTGGAAAAATCATTAAAGAATTCCAA
TAA

Upstream 100 bases:

>100_bases
ATATATAATTTTCTATTTATTGAGAATAGAAAGTACATTATATTGCTGATTAGTAATTATACTTGTTATATTAAAACTCT
AGAAATAGGAAGGTGGCAGA

Downstream 100 bases:

>100_bases
TTAAATAACTTTTTTAAATTTTTTAAATTTCAAAAAAAAAGAGTTTTATTTTAGTTTTAAAGGTTTATTTGGCCTTTGAT
TTTTCAATGTATTTTTCAAT

Product: methylenetetrahydromethanopterin reductase

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKFGIEFVPNEPITKLAYYVKLAEDNGFEFCWITDHYNNRNVYMTLGNLAAATNKIKLGPGVTNPYVRSPAIAASAMATV
DELSGGRATFGIGPGDKATFDALGIEWTKPVGTIKKAIADFKELTAGKRMAEGAQLAVKPSAKIPIYMGAQGPKMLETAG
EIADGVLINASNPKDFEAAVPLIKKGAEAAGRSMSEIDVAAYACMSVDKKAEKAKQAAIPVVAFIAAGSPPMILERHGID
PAKVDAIRAGLKEGNFGAAFGNVDENMLEGFALYGTPEEVVEKVKALEKMGVTQVVAGSPIGPNKDTSIKLIGKIIKEFQ

Sequences:

>Translated_320_residues
MKFGIEFVPNEPITKLAYYVKLAEDNGFEFCWITDHYNNRNVYMTLGNLAAATNKIKLGPGVTNPYVRSPAIAASAMATV
DELSGGRATFGIGPGDKATFDALGIEWTKPVGTIKKAIADFKELTAGKRMAEGAQLAVKPSAKIPIYMGAQGPKMLETAG
EIADGVLINASNPKDFEAAVPLIKKGAEAAGRSMSEIDVAAYACMSVDKKAEKAKQAAIPVVAFIAAGSPPMILERHGID
PAKVDAIRAGLKEGNFGAAFGNVDENMLEGFALYGTPEEVVEKVKALEKMGVTQVVAGSPIGPNKDTSIKLIGKIIKEFQ
>Mature_320_residues
MKFGIEFVPNEPITKLAYYVKLAEDNGFEFCWITDHYNNRNVYMTLGNLAAATNKIKLGPGVTNPYVRSPAIAASAMATV
DELSGGRATFGIGPGDKATFDALGIEWTKPVGTIKKAIADFKELTAGKRMAEGAQLAVKPSAKIPIYMGAQGPKMLETAG
EIADGVLINASNPKDFEAAVPLIKKGAEAAGRSMSEIDVAAYACMSVDKKAEKAKQAAIPVVAFIAAGSPPMILERHGID
PAKVDAIRAGLKEGNFGAAFGNVDENMLEGFALYGTPEEVVEKVKALEKMGVTQVVAGSPIGPNKDTSIKLIGKIIKEFQ

Specific function: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 33823; Mature: 33823

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGIEFVPNEPITKLAYYVKLAEDNGFEFCWITDHYNNRNVYMTLGNLAAATNKIKLGP
CCCCCEECCCCCHHHEEEEEEEECCCCEEEEEEECCCCCCEEEEEECCHHHCCCEEEECC
GVTNPYVRSPAIAASAMATVDELSGGRATFGIGPGDKATFDALGIEWTKPVGTIKKAIAD
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHCCCEECCCHHHHHHHHHH
FKELTAGKRMAEGAQLAVKPSAKIPIYMGAQGPKMLETAGEIADGVLINASNPKDFEAAV
HHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHCCEEEECCCCCCHHHHH
PLIKKGAEAAGRSMSEIDVAAYACMSVDKKAEKAKQAAIPVVAFIAAGSPPMILERHGID
HHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCC
PAKVDAIRAGLKEGNFGAAFGNVDENMLEGFALYGTPEEVVEKVKALEKMGVTQVVAGSP
HHHHHHHHHCCCCCCCCCEECCCCHHHHCCEEEECCHHHHHHHHHHHHHCCCCEEECCCC
IGPNKDTSIKLIGKIIKEFQ
CCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKFGIEFVPNEPITKLAYYVKLAEDNGFEFCWITDHYNNRNVYMTLGNLAAATNKIKLGP
CCCCCEECCCCCHHHEEEEEEEECCCCEEEEEEECCCCCCEEEEEECCHHHCCCEEEECC
GVTNPYVRSPAIAASAMATVDELSGGRATFGIGPGDKATFDALGIEWTKPVGTIKKAIAD
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHCCCEECCCHHHHHHHHHH
FKELTAGKRMAEGAQLAVKPSAKIPIYMGAQGPKMLETAGEIADGVLINASNPKDFEAAV
HHHHHHHHHHHCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHCCEEEECCCCCCHHHHH
PLIKKGAEAAGRSMSEIDVAAYACMSVDKKAEKAKQAAIPVVAFIAAGSPPMILERHGID
HHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCC
PAKVDAIRAGLKEGNFGAAFGNVDENMLEGFALYGTPEEVVEKVKALEKMGVTQVVAGSP
HHHHHHHHHCCCCCCCCCEECCCCHHHHCCEEEECCHHHHHHHHHHHHHCCCCEEECCCC
IGPNKDTSIKLIGKIIKEFQ
CCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]