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The map label for this gene is moaC [H]

Identifier: 161621698

GI number: 161621698

Start: 1058344

End: 1058805

Strand: Direct

Name: moaC [H]

Synonym: MMP1066

Alternate gene names: 161621698

Gene position: 1058344-1058805 (Clockwise)

Preceding gene: 45358626

Following gene: 45358636

Centisome position: 63.71

GC content: 32.25

Gene sequence:

>462_bases
GTGCTTACACATGTTGATGAAAATGGCGTAAAAATGGTCGATGTTTCTAATAAAAAAGACGTCGAACGAATTTGTACTGC
AGTTGGTTTTATAAAACTTAAAAAATCAACCATTGAAAAAATTACAAAAAAAGAACTTATAAAAGGCGATGTTTTAACCA
CTGCTCAAGTTGCAGGAGTTATGGCAGTTAAAAACACTTCAAATATCATTCCAATGTGCCACCCGCTTCCAATTGAATCC
ATAAAAGTTAATTTTGAGATTTTTGAAGATAAAATAAAAGCAGAAGCAAGAGTAAAGGCAACATACAAAACCGGAATCGA
AATGGAAAGTTTAACAGGGGTTTCTGTTGCACTTTTAACGATTTGGGACATGGTAAAAGCAATTGAAAAGGATGAATTTG
GACAGTATCCGAACACCCAAATTTATGGAATAGAAGTTACTGAAAAAATTAAAAAAGAATAA

Upstream 100 bases:

>100_bases
AACGTGTAAATCAAATAACTTAAATAAAATCACATGTCTATATACGAATATTCTTTTTCTTAATGTTATCTATTTTATTC
ATTCAAAAAAGGCGATTATC

Downstream 100 bases:

>100_bases
ATTATTTGATTTTTTGTTTTAAATCACTTTATCGAGCAGCGAAATTATATTCATTACTGGAATATCTTTTTTTAAACCGT
GTTCTTTAAGATATTTTGTT

Product: putative molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MLTHVDENGVKMVDVSNKKDVERICTAVGFIKLKKSTIEKITKKELIKGDVLTTAQVAGVMAVKNTSNIIPMCHPLPIES
IKVNFEIFEDKIKAEARVKATYKTGIEMESLTGVSVALLTIWDMVKAIEKDEFGQYPNTQIYGIEVTEKIKKE

Sequences:

>Translated_153_residues
MLTHVDENGVKMVDVSNKKDVERICTAVGFIKLKKSTIEKITKKELIKGDVLTTAQVAGVMAVKNTSNIIPMCHPLPIES
IKVNFEIFEDKIKAEARVKATYKTGIEMESLTGVSVALLTIWDMVKAIEKDEFGQYPNTQIYGIEVTEKIKKE
>Mature_153_residues
MLTHVDENGVKMVDVSNKKDVERICTAVGFIKLKKSTIEKITKKELIKGDVLTTAQVAGVMAVKNTSNIIPMCHPLPIES
IKVNFEIFEDKIKAEARVKATYKTGIEMESLTGVSVALLTIWDMVKAIEKDEFGQYPNTQIYGIEVTEKIKKE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=133, Percent_Identity=42.8571428571429, Blast_Score=111, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32566331, Length=133, Percent_Identity=39.8496240601504, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28574490, Length=133, Percent_Identity=42.1052631578947, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28574492, Length=122, Percent_Identity=40.9836065573771, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023047
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17102; Mature: 17102

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTHVDENGVKMVDVSNKKDVERICTAVGFIKLKKSTIEKITKKELIKGDVLTTAQVAGV
CCCEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHE
MAVKNTSNIIPMCHPLPIESIKVNFEIFEDKIKAEARVKATYKTGIEMESLTGVSVALLT
EEECCCCCCCCCCCCCCCCCEEEEHEEHHHHHHHHHHEEEHHHCCCCHHHHCCHHHHHHH
IWDMVKAIEKDEFGQYPNTQIYGIEVTEKIKKE
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHCCC
>Mature Secondary Structure
MLTHVDENGVKMVDVSNKKDVERICTAVGFIKLKKSTIEKITKKELIKGDVLTTAQVAGV
CCCEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHE
MAVKNTSNIIPMCHPLPIESIKVNFEIFEDKIKAEARVKATYKTGIEMESLTGVSVALLT
EEECCCCCCCCCCCCCCCCCEEEEHEEHHHHHHHHHHEEEHHHCCCCHHHHCCHHHHHHH
IWDMVKAIEKDEFGQYPNTQIYGIEVTEKIKKE
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]