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The map label for this gene is crtI [H]

Identifier: 42523220

GI number: 42523220

Start: 1659663

End: 1661150

Strand: Direct

Name: crtI [H]

Synonym: Bd1724

Alternate gene names: 42523220

Gene position: 1659663-1661150 (Clockwise)

Preceding gene: 42523219

Following gene: 42523221

Centisome position: 43.87

GC content: 50.0

Gene sequence:

>1488_bases
ATGCCTATGAATAAAAAAGTTGCAGTAATTGGAAGTGGATTCGGTGGATTGAGTGCCGCCATTCGTCTTCAGGCCGCGGG
CTTTGAAGTTCGTATTTTTGAAAAGCGGGATATGCCTGGTGGCCGGGCCTATGTTTACCGGGACAAGGGATTCACCTTTG
ATGCCGGACCGACGGTGATCACCGCTCCGGAATGTCTGGAAGAACTTTTTGCCCTGAAAAACAAAAAGATGTCCGACTAT
GTTGAGATGATTCCTGTTTCGCCATTTTATCGCCTGCTGTGGGATGATGGTTACAAGTTTGATTACAGCAATAATACCGA
CGAACTTTATGCCCAGATTCAGAAAAAATCCCCGGACGATGCCAAGGGGTATGAGAAGTTCTTAAAATATTCTGAAGAGG
TCTTTAACGAGGGCTACACCAAACTGGTGGCAACACCTTTCCTGCATCTTTGGAGCATGGTAAAGGTTTCCCCGCAGCTT
CTTCGTCTGGGAGCCTATCGCAGTGTTTATTCAGTGGTTTCAAAGTACGTCAAAGACGATCATCTGCGCCAGGCCTTTTC
TTTTCATTCCCTGCTGGTCGGGGGGAATCCTTACAGCACGTCGGCTATTTATACCCTGATTCATTTCCTGGAAAGAAACT
GGGGCGTGTTCTTCCCACGCGGCGGGACCGGAGCTTTGGTGCAGGCGCTGGTGCGCTACTTTACTGAAATGGGTGGTGAG
ATCCGCTGCCAAAGTGAAATCTCCCGGATTCTGACCTCTGACGGTAAAGTCACAGGCATCAGAACTGTTCAAGGGGATGT
CTGGGAATGTGATGCCGTGGTCAGCAATGGCGATATCGTGCACACCTACCGCGATCTGCTGGGGCAAGAACCCCTGGCGG
CGAAAAAATCCAAAGAGATGCAGAACAAAGACTTCAGCATGAGTTTGTTCCTGATCTATTTTGGCACGAAGAAAAAGTAT
CCGCATCTGGCCCATCACAATGTTCTGTTCGGCCCCCGCTACAAAGGGCTGCTGGAGGATATTTTCAGCAACGGGACTTT
GCCGGATGATTTTTCACTGTACTTGCATGTGCCCAGTTTGACCGATCCGAATCTGGCGCCGGAAGGGCATGAGTGCTTCT
ATGTTCTTGCTCCGGTCGCGCATCTGGGCAAGATGAACATCGACTGGAAAAAAGAAGGTCCGGTCTATGCGGAAAAGATC
CTGAAATACATGGAAGAAAAATACATGCCGGGGCTGCGGGAAAATATCGTGACCCAAAGAATATTCACCCCCGAGGATTT
CTCCACAGAGCTGAATTCGTTCCATGGCTCGGCGTTTTCGCTGGAACCAAAACTGACTCAAAGTGCTTACTTCCGTCAGC
ACAATAAGGATTCGCAGATTCAAGGACTGTACTTTGTGGGGGCGGGGACACACCCCGGTGCCGGGGTCCCAGGGGTTGTG
AACTCTGGTAAAGCCACAGCCGGTTTGGTTGTTGAGGACCTTGTTTGA

Upstream 100 bases:

>100_bases
CTTCATCGTGAAATGGAAGAAAGACTGAAAGCGTCTTTTGCCGGTCTTGAGAACGCCCAGACACTAAACCTACTAAAAAA
CCTGACAGAGAGAATTGTCC

Downstream 100 bases:

>100_bases
TGACGCTGAACCAGGATCTGGAGCTGCATAAACAGAGCATCCAAAAAGGCTCAAAAAGTTTTGCCCTGGCTTCTTTGTTT
TTTTCAAAGCAACAGAAGCT

Product: phytoene dehydrogenase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MPMNKKVAVIGSGFGGLSAAIRLQAAGFEVRIFEKRDMPGGRAYVYRDKGFTFDAGPTVITAPECLEELFALKNKKMSDY
VEMIPVSPFYRLLWDDGYKFDYSNNTDELYAQIQKKSPDDAKGYEKFLKYSEEVFNEGYTKLVATPFLHLWSMVKVSPQL
LRLGAYRSVYSVVSKYVKDDHLRQAFSFHSLLVGGNPYSTSAIYTLIHFLERNWGVFFPRGGTGALVQALVRYFTEMGGE
IRCQSEISRILTSDGKVTGIRTVQGDVWECDAVVSNGDIVHTYRDLLGQEPLAAKKSKEMQNKDFSMSLFLIYFGTKKKY
PHLAHHNVLFGPRYKGLLEDIFSNGTLPDDFSLYLHVPSLTDPNLAPEGHECFYVLAPVAHLGKMNIDWKKEGPVYAEKI
LKYMEEKYMPGLRENIVTQRIFTPEDFSTELNSFHGSAFSLEPKLTQSAYFRQHNKDSQIQGLYFVGAGTHPGAGVPGVV
NSGKATAGLVVEDLV

Sequences:

>Translated_495_residues
MPMNKKVAVIGSGFGGLSAAIRLQAAGFEVRIFEKRDMPGGRAYVYRDKGFTFDAGPTVITAPECLEELFALKNKKMSDY
VEMIPVSPFYRLLWDDGYKFDYSNNTDELYAQIQKKSPDDAKGYEKFLKYSEEVFNEGYTKLVATPFLHLWSMVKVSPQL
LRLGAYRSVYSVVSKYVKDDHLRQAFSFHSLLVGGNPYSTSAIYTLIHFLERNWGVFFPRGGTGALVQALVRYFTEMGGE
IRCQSEISRILTSDGKVTGIRTVQGDVWECDAVVSNGDIVHTYRDLLGQEPLAAKKSKEMQNKDFSMSLFLIYFGTKKKY
PHLAHHNVLFGPRYKGLLEDIFSNGTLPDDFSLYLHVPSLTDPNLAPEGHECFYVLAPVAHLGKMNIDWKKEGPVYAEKI
LKYMEEKYMPGLRENIVTQRIFTPEDFSTELNSFHGSAFSLEPKLTQSAYFRQHNKDSQIQGLYFVGAGTHPGAGVPGVV
NSGKATAGLVVEDLV
>Mature_494_residues
PMNKKVAVIGSGFGGLSAAIRLQAAGFEVRIFEKRDMPGGRAYVYRDKGFTFDAGPTVITAPECLEELFALKNKKMSDYV
EMIPVSPFYRLLWDDGYKFDYSNNTDELYAQIQKKSPDDAKGYEKFLKYSEEVFNEGYTKLVATPFLHLWSMVKVSPQLL
RLGAYRSVYSVVSKYVKDDHLRQAFSFHSLLVGGNPYSTSAIYTLIHFLERNWGVFFPRGGTGALVQALVRYFTEMGGEI
RCQSEISRILTSDGKVTGIRTVQGDVWECDAVVSNGDIVHTYRDLLGQEPLAAKKSKEMQNKDFSMSLFLIYFGTKKKYP
HLAHHNVLFGPRYKGLLEDIFSNGTLPDDFSLYLHVPSLTDPNLAPEGHECFYVLAPVAHLGKMNIDWKKEGPVYAEKIL
KYMEEKYMPGLRENIVTQRIFTPEDFSTELNSFHGSAFSLEPKLTQSAYFRQHNKDSQIQGLYFVGAGTHPGAGVPGVVN
SGKATAGLVVEDLV

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI229577391, Length=550, Percent_Identity=24.1818181818182, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540238, Length=525, Percent_Identity=22.2857142857143, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 55647; Mature: 55516

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS00982 PHYTOENE_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMNKKVAVIGSGFGGLSAAIRLQAAGFEVRIFEKRDMPGGRAYVYRDKGFTFDAGPTVI
CCCCCEEEEEECCCCCHHHEEEEEECCEEEEEEECCCCCCCCEEEEECCCEEECCCCCEE
TAPECLEELFALKNKKMSDYVEMIPVSPFYRLLWDDGYKFDYSNNTDELYAQIQKKSPDD
ECHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCC
AKGYEKFLKYSEEVFNEGYTKLVATPFLHLWSMVKVSPQLLRLGAYRSVYSVVSKYVKDD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
HLRQAFSFHSLLVGGNPYSTSAIYTLIHFLERNWGVFFPRGGTGALVQALVRYFTEMGGE
HHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCC
IRCQSEISRILTSDGKVTGIRTVQGDVWECDAVVSNGDIVHTYRDLLGQEPLAAKKSKEM
EEEHHHHHHHHHCCCCEEEEEEECCCCEEECEEECCCCCHHHHHHHHCCCCCHHHHHHHH
QNKDFSMSLFLIYFGTKKKYPHLAHHNVLFGPRYKGLLEDIFSNGTLPDDFSLYLHVPSL
CCCCCCEEEEEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCCCCEEEEEECCC
TDPNLAPEGHECFYVLAPVAHLGKMNIDWKKEGPVYAEKILKYMEEKYMPGLRENIVTQR
CCCCCCCCCCCEEEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
IFTPEDFSTELNSFHGSAFSLEPKLTQSAYFRQHNKDSQIQGLYFVGAGTHPGAGVPGVV
CCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCC
NSGKATAGLVVEDLV
CCCCCCCCCHHHHCC
>Mature Secondary Structure 
PMNKKVAVIGSGFGGLSAAIRLQAAGFEVRIFEKRDMPGGRAYVYRDKGFTFDAGPTVI
CCCCEEEEEECCCCCHHHEEEEEECCEEEEEEECCCCCCCCEEEEECCCEEECCCCCEE
TAPECLEELFALKNKKMSDYVEMIPVSPFYRLLWDDGYKFDYSNNTDELYAQIQKKSPDD
ECHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCC
AKGYEKFLKYSEEVFNEGYTKLVATPFLHLWSMVKVSPQLLRLGAYRSVYSVVSKYVKDD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
HLRQAFSFHSLLVGGNPYSTSAIYTLIHFLERNWGVFFPRGGTGALVQALVRYFTEMGGE
HHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCC
IRCQSEISRILTSDGKVTGIRTVQGDVWECDAVVSNGDIVHTYRDLLGQEPLAAKKSKEM
EEEHHHHHHHHHCCCCEEEEEEECCCCEEECEEECCCCCHHHHHHHHCCCCCHHHHHHHH
QNKDFSMSLFLIYFGTKKKYPHLAHHNVLFGPRYKGLLEDIFSNGTLPDDFSLYLHVPSL
CCCCCCEEEEEEEECCCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCCCCEEEEEECCC
TDPNLAPEGHECFYVLAPVAHLGKMNIDWKKEGPVYAEKILKYMEEKYMPGLRENIVTQR
CCCCCCCCCCCEEEEEECHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
IFTPEDFSTELNSFHGSAFSLEPKLTQSAYFRQHNKDSQIQGLYFVGAGTHPGAGVPGVV
CCCCCCHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCC
NSGKATAGLVVEDLV
CCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2254247 [H]