Click here to switch to the map view.

The map label for this gene is hppA [H]

Identifier: 42523211

GI number: 42523211

Start: 1651395

End: 1653461

Strand: Direct

Name: hppA [H]

Synonym: Bd1715

Alternate gene names: 42523211

Gene position: 1651395-1653461 (Clockwise)

Preceding gene: 42523207

Following gene: 42523212

Centisome position: 43.65

GC content: 52.1

Gene sequence:

>2067_bases
ATGTTTAGTGAATCTTTGCTGATCTCTCCTGCAATTGCAGGGGTCGTTGGTTTGATCGTTGCTTTGGCTCTGTACCTTCG
CGTGAAGGCACAACCAGCGGGCAATGAGACAATGAATCGTATCGCGTCCTACGTGCGCGAAGGTTCTATGGCGTTCCTTG
TGCGTGAGTACAAGGTCCTTTTCGTCTACGCAATCGTCGTAGGCTTGGCTCTTTGGTTCGCCTTGGGCGGTATCGCAGCA
GGATCCTTCATCCTGGGTGCGTTCCTGTCTTTGCTTGCGGGCTTCTTCGGTATGAAGGCGGCAACTTATGCCAACGTTCG
TACCTCTCAAGCCGCAGCTGGCGGTTCTAAAGCGGCGGCATTGCTGGTTGCTTTGGACGGCGGCGCTGTAATGGGTCTTT
CCGTTGCAGGTCTTGGTTTGATCGGTCTTGGTGGTTTGTATGTTGCCTTCCAGGGTGATGCTCACCTGGGCACAATCCTT
CACTCCTTCGCAGTGGGTGCTTCCTCTATCGCTCTATTTGCGCGTATCGGTGGTGGTATCTACACTAAAGCGGCGGACGT
GGGTGCCGACATCGCTGGTAAAGTTGTAGAAAACATCCCTGAAGACGACCCTCGTAACCCTGGTGTAATCGCCGACAACG
TTGGTGACAACGTGGGTGACGTTGCTGGTATGGGCGCAGACATCTATGAGTCCATGGTTGCTGCGATCGTTTCTGCTATG
GCGATTGCTTTGACAATCCCTGCAGAAGGTCTTTCTGCTTTGATGACGGGTGCGGATGCTGAGACGGTGCGTGTTGCCGG
TGTTGCATTGCCAATCCTGTTGTCCACTTTGGGTCTGGTGATCTCTATCATCGTTATCTTTGCTGCTCGCGCGTTCAAAA
ACGGCAAGCCTGCAACTGTATTGCGTAATGCTTTGATCTTCCCTCCAATTCTTTTGACTATCGCTGCTTACATCATTCTT
CCGATGTTCGGCATCAATCAGAGTGTGACTGTGGCTTTGGCTGCGGGTGCGTTCGGTGGTGCTTTGATCGGTTTGATCAC
TGAGTACTACACAGCGGCTCGTCCCATCCGTCTGGTTGCTGAAGCGGCTTTGACTGGTGCGGGCACTGGTGTGATCCGTG
GTTTGGCAGTGGGTATGGAATCCACAGCGATCCCAATGTTGATCGTTGTTATCGCAGCTTACGTGGCTGACCAGGCTTTG
GGTCTGTACGGTATCGCAATGGCGGCAGTGGGTATGTTGGCTGGTACTGCAGTTGTAATGACTGTAGATGCTTACGGTCC
AATCGCTGACAACGCGGGTGGTATCTCTGAAATGTCCGGTCTGGGCAAAGACGTTCGTGCGATCACTGACGAATTGGATG
CGGTTGGTAATACAACGGCAGCTATCGGTAAAGGTTTCGCGATCGGTTCTGCGATCCTGACAGTTGTGGCATTGTTCTCT
GCATTCAACATGGAAGTAAACCACGTTCGTGAGGGCGCGGGTCTTGCTAAAATGTCTTTGGATCTGACTTCTTCCGGCGT
TCTGATCGGTATCTTGTTGGGCTCTATCCTTCCATTCCTGGTGGGTGCGACAACAATGACTGCGGTTGGTAAAGCGGCTC
AGAAAATCGTTCAAGAGATCGCTCGTCAATTCAAAGAAATCCCAGGTCTTCGTGAAGGTAAAGCGGAACCACAACCAGCT
AAGATCGTGGACATTGCAACTCAGGCTGCATTGTTCGAAATGATCCTGCCAGGTATGATCGCGATCCTTGCTCCAGTGGC
AGTTGGTTTCTTGTTGGGGCCTCAGGCTTTGGCAGGTCTACTTGCTGGTGGTTTGGCTGTCGGTGCAACTATGTCCCTGT
TCATGGCGAACGCGGGTGGTGCATGGGATAACGCTAAGAAATACATCGAAAAAGGCGGCCTTCCAGGTCATCCAAAAGGT
TCCGATGCTCACAAAGCAGCGGTTGTTGGTGACACTGTCGGTGACCCGTTCAAAGACACTTCCGGTCCTGGCGTTGCGAT
CCTTATCAAAGTTATGTCCGTCGTATCTTTGTTGATCGCTCAATTGATCGCTACTATCGGCGGCTAA

Upstream 100 bases:

>100_bases
TTCAGCTGCTACGGCCCCCTCCCAGATTGACTCGATGTAATGAGACGCGGTAACTCTAAGCCTTCGTAATTAAAACGAGA
AATCATAAACGGAGTGCAAC

Downstream 100 bases:

>100_bases
GGCGCGGCAGCGCAGGAGGCCGTAGGGCCGCTACTCCGGCACTGCCGGAGTGTAAGCGGTCGCGAAGGCTGGACTTCGGC
TCTGCCGAGGAGGCGTAGCT

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound sodium-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; Na(+)-PPase [H]

Number of amino acids: Translated: 688; Mature: 688

Protein sequence:

>688_residues
MFSESLLISPAIAGVVGLIVALALYLRVKAQPAGNETMNRIASYVREGSMAFLVREYKVLFVYAIVVGLALWFALGGIAA
GSFILGAFLSLLAGFFGMKAATYANVRTSQAAAGGSKAAALLVALDGGAVMGLSVAGLGLIGLGGLYVAFQGDAHLGTIL
HSFAVGASSIALFARIGGGIYTKAADVGADIAGKVVENIPEDDPRNPGVIADNVGDNVGDVAGMGADIYESMVAAIVSAM
AIALTIPAEGLSALMTGADAETVRVAGVALPILLSTLGLVISIIVIFAARAFKNGKPATVLRNALIFPPILLTIAAYIIL
PMFGINQSVTVALAAGAFGGALIGLITEYYTAARPIRLVAEAALTGAGTGVIRGLAVGMESTAIPMLIVVIAAYVADQAL
GLYGIAMAAVGMLAGTAVVMTVDAYGPIADNAGGISEMSGLGKDVRAITDELDAVGNTTAAIGKGFAIGSAILTVVALFS
AFNMEVNHVREGAGLAKMSLDLTSSGVLIGILLGSILPFLVGATTMTAVGKAAQKIVQEIARQFKEIPGLREGKAEPQPA
KIVDIATQAALFEMILPGMIAILAPVAVGFLLGPQALAGLLAGGLAVGATMSLFMANAGGAWDNAKKYIEKGGLPGHPKG
SDAHKAAVVGDTVGDPFKDTSGPGVAILIKVMSVVSLLIAQLIATIGG

Sequences:

>Translated_688_residues
MFSESLLISPAIAGVVGLIVALALYLRVKAQPAGNETMNRIASYVREGSMAFLVREYKVLFVYAIVVGLALWFALGGIAA
GSFILGAFLSLLAGFFGMKAATYANVRTSQAAAGGSKAAALLVALDGGAVMGLSVAGLGLIGLGGLYVAFQGDAHLGTIL
HSFAVGASSIALFARIGGGIYTKAADVGADIAGKVVENIPEDDPRNPGVIADNVGDNVGDVAGMGADIYESMVAAIVSAM
AIALTIPAEGLSALMTGADAETVRVAGVALPILLSTLGLVISIIVIFAARAFKNGKPATVLRNALIFPPILLTIAAYIIL
PMFGINQSVTVALAAGAFGGALIGLITEYYTAARPIRLVAEAALTGAGTGVIRGLAVGMESTAIPMLIVVIAAYVADQAL
GLYGIAMAAVGMLAGTAVVMTVDAYGPIADNAGGISEMSGLGKDVRAITDELDAVGNTTAAIGKGFAIGSAILTVVALFS
AFNMEVNHVREGAGLAKMSLDLTSSGVLIGILLGSILPFLVGATTMTAVGKAAQKIVQEIARQFKEIPGLREGKAEPQPA
KIVDIATQAALFEMILPGMIAILAPVAVGFLLGPQALAGLLAGGLAVGATMSLFMANAGGAWDNAKKYIEKGGLPGHPKG
SDAHKAAVVGDTVGDPFKDTSGPGVAILIKVMSVVSLLIAQLIATIGG
>Mature_688_residues
MFSESLLISPAIAGVVGLIVALALYLRVKAQPAGNETMNRIASYVREGSMAFLVREYKVLFVYAIVVGLALWFALGGIAA
GSFILGAFLSLLAGFFGMKAATYANVRTSQAAAGGSKAAALLVALDGGAVMGLSVAGLGLIGLGGLYVAFQGDAHLGTIL
HSFAVGASSIALFARIGGGIYTKAADVGADIAGKVVENIPEDDPRNPGVIADNVGDNVGDVAGMGADIYESMVAAIVSAM
AIALTIPAEGLSALMTGADAETVRVAGVALPILLSTLGLVISIIVIFAARAFKNGKPATVLRNALIFPPILLTIAAYIIL
PMFGINQSVTVALAAGAFGGALIGLITEYYTAARPIRLVAEAALTGAGTGVIRGLAVGMESTAIPMLIVVIAAYVADQAL
GLYGIAMAAVGMLAGTAVVMTVDAYGPIADNAGGISEMSGLGKDVRAITDELDAVGNTTAAIGKGFAIGSAILTVVALFS
AFNMEVNHVREGAGLAKMSLDLTSSGVLIGILLGSILPFLVGATTMTAVGKAAQKIVQEIARQFKEIPGLREGKAEPQPA
KIVDIATQAALFEMILPGMIAILAPVAVGFLLGPQALAGLLAGGLAVGATMSLFMANAGGAWDNAKKYIEKGGLPGHPKG
SDAHKAAVVGDTVGDPFKDTSGPGVAILIKVMSVVSLLIAQLIATIGG

Specific function: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 69154; Mature: 69154

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSESLLISPAIAGVVGLIVALALYLRVKAQPAGNETMNRIASYVREGSMAFLVREYKVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
FVYAIVVGLALWFALGGIAAGSFILGAFLSLLAGFFGMKAATYANVRTSQAAAGGSKAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEE
LLVALDGGAVMGLSVAGLGLIGLGGLYVAFQGDAHLGTILHSFAVGASSIALFARIGGGI
EEEEECCCCEEHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCHHHHHHHHHHCCCC
YTKAADVGADIAGKVVENIPEDDPRNPGVIADNVGDNVGDVAGMGADIYESMVAAIVSAM
EEHHHHCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHH
AIALTIPAEGLSALMTGADAETVRVAGVALPILLSTLGLVISIIVIFAARAFKNGKPATV
HHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LRNALIFPPILLTIAAYIILPMFGINQSVTVALAAGAFGGALIGLITEYYTAARPIRLVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHH
EAALTGAGTGVIRGLAVGMESTAIPMLIVVIAAYVADQALGLYGIAMAAVGMLAGTAVVM
HHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
TVDAYGPIADNAGGISEMSGLGKDVRAITDELDAVGNTTAAIGKGFAIGSAILTVVALFS
EEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHH
AFNMEVNHVREGAGLAKMSLDLTSSGVLIGILLGSILPFLVGATTMTAVGKAAQKIVQEI
HHCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQFKEIPGLREGKAEPQPAKIVDIATQAALFEMILPGMIAILAPVAVGFLLGPQALAGL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LAGGLAVGATMSLFMANAGGAWDNAKKYIEKGGLPGHPKGSDAHKAAVVGDTVGDPFKDT
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCC
SGPGVAILIKVMSVVSLLIAQLIATIGG
CCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFSESLLISPAIAGVVGLIVALALYLRVKAQPAGNETMNRIASYVREGSMAFLVREYKVL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
FVYAIVVGLALWFALGGIAAGSFILGAFLSLLAGFFGMKAATYANVRTSQAAAGGSKAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEE
LLVALDGGAVMGLSVAGLGLIGLGGLYVAFQGDAHLGTILHSFAVGASSIALFARIGGGI
EEEEECCCCEEHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCHHHHHHHHHHCCCC
YTKAADVGADIAGKVVENIPEDDPRNPGVIADNVGDNVGDVAGMGADIYESMVAAIVSAM
EEHHHHCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHCCCHHHHHHHHHHHHHHH
AIALTIPAEGLSALMTGADAETVRVAGVALPILLSTLGLVISIIVIFAARAFKNGKPATV
HHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LRNALIFPPILLTIAAYIILPMFGINQSVTVALAAGAFGGALIGLITEYYTAARPIRLVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHH
EAALTGAGTGVIRGLAVGMESTAIPMLIVVIAAYVADQALGLYGIAMAAVGMLAGTAVVM
HHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
TVDAYGPIADNAGGISEMSGLGKDVRAITDELDAVGNTTAAIGKGFAIGSAILTVVALFS
EEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHH
AFNMEVNHVREGAGLAKMSLDLTSSGVLIGILLGSILPFLVGATTMTAVGKAAQKIVQEI
HHCCHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARQFKEIPGLREGKAEPQPAKIVDIATQAALFEMILPGMIAILAPVAVGFLLGPQALAGL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LAGGLAVGATMSLFMANAGGAWDNAKKYIEKGGLPGHPKGSDAHKAAVVGDTVGDPFKDT
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCC
SGPGVAILIKVMSVVSLLIAQLIATIGG
CCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]