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The map label for this gene is msbB [H]

Identifier: 42523007

GI number: 42523007

Start: 1419393

End: 1420277

Strand: Direct

Name: msbB [H]

Synonym: Bd1500

Alternate gene names: 42523007

Gene position: 1419393-1420277 (Clockwise)

Preceding gene: 42523006

Following gene: 42523008

Centisome position: 37.52

GC content: 48.02

Gene sequence:

>885_bases
ATGAGATTATTACTCAAGTTCTTCGTTAATTTGATGGTCTTTATCAGTTCCCTGGTGCCGCGCCGTTGGTTGCGCAAGTC
CGGGTCCTGGGTGGGCTTTTTGTGGTTTGATGTCTTTGGTTTTCGCAAAAAAATCGTTCTGGATAATTTGAAACTGGCTT
TCCCCGAGTGGACCGACCAGCAACGAAAAGCCGTCGGTCGCGAATCTGTGTATCAGCTGGGTTATAACTTTGCTGAATTC
TTTTTCATTCCGTCTGTGACGCCTGAATGGATCGCCAAGAATGTGGTGTTTCACGGCTGGGAGCATGTTGAAAATGCCCG
GGCTGCAGGGAAAGGAATGTTTTTCCTGACTTTGCATTTGGGGAACGGGGATCTGGCCTGTAACACGATTGTCCTAAACG
GGCAGAGTGTGAACCTGATCACGAAAAGATTTAAAACGAAATGGTTTGATGATCTGTGGTTTTCTATTCGCGGAGCCAAG
GGTGTGCAGTATATCGATGCCCACGCACCGAACAATGCTTTTGAGATTTTGAAGGCGTTGAAAAAGAATTCGGCGGTGGT
CTTTGTTCTGGATCAGTTTATGGGGCGTCCCTTTGGGATTGAGACCTCCTTCTTCGGGAAAAAGACGGGCACAGCCTATG
GTCTAGCTCTGTTTGTGCAAAAAACCAAAGCCCCGGTTCTTCCCATCTATACCTACGAGGGGGAAGATAAAAAACTTCAT
GTGGTTGTCGAGCCAGCGATGGACACGGCTTCCTGTGTGACTGATGATAAAGACCAGACGACTCTCAATCTGACACAAAG
CTATTGCGACAAGTTGGAAGAGATCGTCAGAAAGCACCCGGAACAATGGATGTGGGTGCATCGACGGTGGAAGGATTTCC
GGTGA

Upstream 100 bases:

>100_bases
GGCAAGGATGCAGTGAAGCTCCGTCAGTTGTTCAATGATACCGCCATCCTGTGGAGCACTTCGTTGGAAGTTGCAGAGTC
AGGCAGGAAGGGACGCCTTC

Downstream 100 bases:

>100_bases
ACTTTAAAATGCTTCTTGGCGTATTCGTTTCTTTGCTTTTGGTTTCCTGTTCGACTTCATTTTTGAAGTACGAAAAAGCT
GACCAGCTGAAAAAAAACGA

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MRLLLKFFVNLMVFISSLVPRRWLRKSGSWVGFLWFDVFGFRKKIVLDNLKLAFPEWTDQQRKAVGRESVYQLGYNFAEF
FFIPSVTPEWIAKNVVFHGWEHVENARAAGKGMFFLTLHLGNGDLACNTIVLNGQSVNLITKRFKTKWFDDLWFSIRGAK
GVQYIDAHAPNNAFEILKALKKNSAVVFVLDQFMGRPFGIETSFFGKKTGTAYGLALFVQKTKAPVLPIYTYEGEDKKLH
VVVEPAMDTASCVTDDKDQTTLNLTQSYCDKLEEIVRKHPEQWMWVHRRWKDFR

Sequences:

>Translated_294_residues
MRLLLKFFVNLMVFISSLVPRRWLRKSGSWVGFLWFDVFGFRKKIVLDNLKLAFPEWTDQQRKAVGRESVYQLGYNFAEF
FFIPSVTPEWIAKNVVFHGWEHVENARAAGKGMFFLTLHLGNGDLACNTIVLNGQSVNLITKRFKTKWFDDLWFSIRGAK
GVQYIDAHAPNNAFEILKALKKNSAVVFVLDQFMGRPFGIETSFFGKKTGTAYGLALFVQKTKAPVLPIYTYEGEDKKLH
VVVEPAMDTASCVTDDKDQTTLNLTQSYCDKLEEIVRKHPEQWMWVHRRWKDFR
>Mature_294_residues
MRLLLKFFVNLMVFISSLVPRRWLRKSGSWVGFLWFDVFGFRKKIVLDNLKLAFPEWTDQQRKAVGRESVYQLGYNFAEF
FFIPSVTPEWIAKNVVFHGWEHVENARAAGKGMFFLTLHLGNGDLACNTIVLNGQSVNLITKRFKTKWFDDLWFSIRGAK
GVQYIDAHAPNNAFEILKALKKNSAVVFVLDQFMGRPFGIETSFFGKKTGTAYGLALFVQKTKAPVLPIYTYEGEDKKLH
VVVEPAMDTASCVTDDKDQTTLNLTQSYCDKLEEIVRKHPEQWMWVHRRWKDFR

Specific function: Transfers myristate or laurate, activated on ACP, to (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI1788161, Length=246, Percent_Identity=23.1707317073171, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011921 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 34110; Mature: 34110

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLKFFVNLMVFISSLVPRRWLRKSGSWVGFLWFDVFGFRKKIVLDNLKLAFPEWTDQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCEEECCCCCCH
QRKAVGRESVYQLGYNFAEFFFIPSVTPEWIAKNVVFHGWEHVENARAAGKGMFFLTLHL
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEEE
GNGDLACNTIVLNGQSVNLITKRFKTKWFDDLWFSIRGAKGVQYIDAHAPNNAFEILKAL
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCCHHHHHHHHH
KKNSAVVFVLDQFMGRPFGIETSFFGKKTGTAYGLALFVQKTKAPVLPIYTYEGEDKKLH
HCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCHHHHEEEEECCCCCEEEEEEECCCCCEEE
VVVEPAMDTASCVTDDKDQTTLNLTQSYCDKLEEIVRKHPEQWMWVHRRWKDFR
EEEECCCCCHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLLLKFFVNLMVFISSLVPRRWLRKSGSWVGFLWFDVFGFRKKIVLDNLKLAFPEWTDQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCEEECCCCCCH
QRKAVGRESVYQLGYNFAEFFFIPSVTPEWIAKNVVFHGWEHVENARAAGKGMFFLTLHL
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEEE
GNGDLACNTIVLNGQSVNLITKRFKTKWFDDLWFSIRGAKGVQYIDAHAPNNAFEILKAL
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCCHHHHHHHHH
KKNSAVVFVLDQFMGRPFGIETSFFGKKTGTAYGLALFVQKTKAPVLPIYTYEGEDKKLH
HCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCHHHHEEEEECCCCCEEEEEEECCCCCEEE
VVVEPAMDTASCVTDDKDQTTLNLTQSYCDKLEEIVRKHPEQWMWVHRRWKDFR
EEEECCCCCHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]