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The map label for this gene is lpxA [H]

Identifier: 42523003

GI number: 42523003

Start: 1415511

End: 1416335

Strand: Direct

Name: lpxA [H]

Synonym: Bd1495

Alternate gene names: 42523003

Gene position: 1415511-1416335 (Clockwise)

Preceding gene: 42523002

Following gene: 42523004

Centisome position: 37.42

GC content: 51.27

Gene sequence:

>825_bases
ATGGCAAATTATAAAATTCATCCAAGCAGTGTTATTTCTCCAGACATCCATATCGCCGACGACGTTGAAATCGGCCCTTA
CTGCTTGATTCAAGGCAAAGGTTTTATTGGCAAAGGCACATTCGTCGAAGGTCATGTGACACTGGGTTCCCGTCACGGCA
TCATCGAAATCGGCGAAAACAATCATTTCTGTCCCGGTGCTGTTATCGGAGGGGCTCCTCAGGACCTTTCCTACAAAGGT
GAACCAACCAAATTGATTATCGGTAACAACAATACATTCCGTGAATTCTCCACCGCCAACCTTGCGACCAGCAAAGGGGA
CGGCAAAACGGAAATCGGCAATAACGGTTACTTCATGGCCTATACGCACATCGGGCATGACTGCAAAGTCGGCAACAATG
TGACCATCGCCAACAACTCCCACTTGGGCGGACACTGTGAAATCGAAGACGGTGTGACCATCGGGGGCGTGTGCGCTTTC
AATCAGTTCACCAAAGTGGGGCGCGGTGCTTTCGTGGCCGGTTCTTCCATCGTGAACAAGGACATCCTGCCGTTCTGCCG
TGCTCAGGGCACTTACGCGACAATCCGCGCGACCAACAAAATCGGTCTGGCGCGTAAAGGTTTCTCGCGTGAAGAAATCG
CAAACGTGCACAAAGCCATCCGTATCATCATCATGGGTTCTCACACCGTGGAAGAAGGCATCGAGCGCATCCTGAATGAG
TGCACGATGAGCCCGAACATCGAGTACTTCGTGAACTTCATTCGCTCTTCCAAGCGCGGTATTGCCGTGGACAGAAGCCC
TAAAGGATGGCAGGACGATGAGTAA

Upstream 100 bases:

>100_bases
CTGACAACTGAAGTAATCGCGGCCTTCGAAAAAGAAAAGTAGTTGATAAGAAAACGAAAGGGCCTGCAAAGGCCCTTTTC
TATTTTAGGAATAGAAGTTC

Downstream 100 bases:

>100_bases
GAAACTTCGTGGCGCGGTTGTCGGGGTGGGTTACCTCGGTAAATTCCACGCCCAGAAATACAAAAACAATCCGAACGTGG
AACTGGTCGGGGTGTGTGAT

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MANYKIHPSSVISPDIHIADDVEIGPYCLIQGKGFIGKGTFVEGHVTLGSRHGIIEIGENNHFCPGAVIGGAPQDLSYKG
EPTKLIIGNNNTFREFSTANLATSKGDGKTEIGNNGYFMAYTHIGHDCKVGNNVTIANNSHLGGHCEIEDGVTIGGVCAF
NQFTKVGRGAFVAGSSIVNKDILPFCRAQGTYATIRATNKIGLARKGFSREEIANVHKAIRIIIMGSHTVEEGIERILNE
CTMSPNIEYFVNFIRSSKRGIAVDRSPKGWQDDE

Sequences:

>Translated_274_residues
MANYKIHPSSVISPDIHIADDVEIGPYCLIQGKGFIGKGTFVEGHVTLGSRHGIIEIGENNHFCPGAVIGGAPQDLSYKG
EPTKLIIGNNNTFREFSTANLATSKGDGKTEIGNNGYFMAYTHIGHDCKVGNNVTIANNSHLGGHCEIEDGVTIGGVCAF
NQFTKVGRGAFVAGSSIVNKDILPFCRAQGTYATIRATNKIGLARKGFSREEIANVHKAIRIIIMGSHTVEEGIERILNE
CTMSPNIEYFVNFIRSSKRGIAVDRSPKGWQDDE
>Mature_273_residues
ANYKIHPSSVISPDIHIADDVEIGPYCLIQGKGFIGKGTFVEGHVTLGSRHGIIEIGENNHFCPGAVIGGAPQDLSYKGE
PTKLIIGNNNTFREFSTANLATSKGDGKTEIGNNGYFMAYTHIGHDCKVGNNVTIANNSHLGGHCEIEDGVTIGGVCAFN
QFTKVGRGAFVAGSSIVNKDILPFCRAQGTYATIRATNKIGLARKGFSREEIANVHKAIRIIIMGSHTVEEGIERILNEC
TMSPNIEYFVNFIRSSKRGIAVDRSPKGWQDDE

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=256, Percent_Identity=36.71875, Blast_Score=171, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 29583; Mature: 29452

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYKIHPSSVISPDIHIADDVEIGPYCLIQGKGFIGKGTFVEGHVTLGSRHGIIEIGEN
CCCCEECCCCCCCCCCEEECCCCCCCEEEEECCCCEECCCEEEEEEEECCCCCEEEECCC
NHFCPGAVIGGAPQDLSYKGEPTKLIIGNNNTFREFSTANLATSKGDGKTEIGNNGYFMA
CCCCCCCEECCCCCCCCCCCCCCEEEECCCCCEEEECCCCEEECCCCCCCEECCCCEEEE
YTHIGHDCKVGNNVTIANNSHLGGHCEIEDGVTIGGVCAFNQFTKVGRGAFVAGSSIVNK
EEECCCCEECCCEEEEECCCCCCCEEEECCCEEEEEEEHHHHHHHHCCCEEEECCHHHCC
DILPFCRAQGTYATIRATNKIGLARKGFSREEIANVHKAIRIIIMGSHTVEEGIERILNE
CCHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHEEEEEEECCCHHHHHHHHHHHH
CTMSPNIEYFVNFIRSSKRGIAVDRSPKGWQDDE
HCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
ANYKIHPSSVISPDIHIADDVEIGPYCLIQGKGFIGKGTFVEGHVTLGSRHGIIEIGEN
CCCEECCCCCCCCCCEEECCCCCCCEEEEECCCCEECCCEEEEEEEECCCCCEEEECCC
NHFCPGAVIGGAPQDLSYKGEPTKLIIGNNNTFREFSTANLATSKGDGKTEIGNNGYFMA
CCCCCCCEECCCCCCCCCCCCCCEEEECCCCCEEEECCCCEEECCCCCCCEECCCCEEEE
YTHIGHDCKVGNNVTIANNSHLGGHCEIEDGVTIGGVCAFNQFTKVGRGAFVAGSSIVNK
EEECCCCEECCCEEEEECCCCCCCEEEECCCEEEEEEEHHHHHHHHCCCEEEECCHHHCC
DILPFCRAQGTYATIRATNKIGLARKGFSREEIANVHKAIRIIIMGSHTVEEGIERILNE
CCHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHEEEEEEECCCHHHHHHHHHHHH
CTMSPNIEYFVNFIRSSKRGIAVDRSPKGWQDDE
HCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA