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The map label for this gene is tatD [H]

Identifier: 42522599

GI number: 42522599

Start: 986630

End: 987400

Strand: Direct

Name: tatD [H]

Synonym: Bd1042

Alternate gene names: 42522599

Gene position: 986630-987400 (Clockwise)

Preceding gene: 42522598

Following gene: 42522601

Centisome position: 26.08

GC content: 50.45

Gene sequence:

>771_bases
ATGGAATGGATCGATATTCACGCACATTTGAATATGCTCGAAGAGGGTGTTGAAGCCGCAATCAACAATGCGAAAGCCGT
GGGCGTGAAGAAGATCATCACCATCGGCACCCAGCCGGAAGATCATCCGATCGTGCTGGATATTGCCCGCAAATATTATC
CGGAAGTGTACTGCACTTTGGGTGTGCATCCTCATGACGGTGGCACTTACACGGAAGCTGCCGGTAAATTTATCGAAGAA
CATGTCACTGAGCCTTGCGTGGTGGCTGTCGGTGAAATCGGTCTGGATTACTATTACGACAATTCCCCGCGTGAACTTCA
GAAGGAAGCCTTCCGCGCACAGCTTGAAATCGCCCGCAGAACCAAAATGCCGGTCGAGATTCACACCCGCGATGCAGAAG
AAGACACCATCGAGATTTTAAAAGAATTCAAAGGCGAAGTGAATGGCCTGATCCATTGCTTTACCGGCACAGAATGGCTG
GCTCGTCAGGCGCTGGACGTGGGTTTCAATATCTCTATCAGTGGTGTGGTGACTTTCAAAAGTGCCGATTCTTTGCGCGA
GACCGTGAAGATGCTGCCACTGGATCGCATCCATGTGGAAACCGATTCACCGTTCCTGGCACCGATCCCGATGCGTGGAC
GCAAGAACACTCCGGCTTATGTTATTCACACGGCGAAGTTCGTGGCTGACCTTAAAGGGATCAGCCTTGAACAACTGTGT
GAACAGACGCGTATCAATGCTCTGAAAATGTTCCCGAAAATTCAGTGGTAG

Upstream 100 bases:

>100_bases
CCGCCAATCGGGATCCTCAGCTGATCATCGAAGAATTCTACGTCACGTCCAAGGCTTAAAGCGCATTGTCACCTTCCGTG
ACGGCTGTTATACTTGCCCT

Downstream 100 bases:

>100_bases
TTTGCAGCAGCTGAGTCCGCGTGGTTTTGATCCACGGGGCAAAGGGTGCAACTTTTGTCGCCTGGGCAATGCCAGCACAG
CTGACCTGTCCGTTCGGTAG

Product: TatD related DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MEWIDIHAHLNMLEEGVEAAINNAKAVGVKKIITIGTQPEDHPIVLDIARKYYPEVYCTLGVHPHDGGTYTEAAGKFIEE
HVTEPCVVAVGEIGLDYYYDNSPRELQKEAFRAQLEIARRTKMPVEIHTRDAEEDTIEILKEFKGEVNGLIHCFTGTEWL
ARQALDVGFNISISGVVTFKSADSLRETVKMLPLDRIHVETDSPFLAPIPMRGRKNTPAYVIHTAKFVADLKGISLEQLC
EQTRINALKMFPKIQW

Sequences:

>Translated_256_residues
MEWIDIHAHLNMLEEGVEAAINNAKAVGVKKIITIGTQPEDHPIVLDIARKYYPEVYCTLGVHPHDGGTYTEAAGKFIEE
HVTEPCVVAVGEIGLDYYYDNSPRELQKEAFRAQLEIARRTKMPVEIHTRDAEEDTIEILKEFKGEVNGLIHCFTGTEWL
ARQALDVGFNISISGVVTFKSADSLRETVKMLPLDRIHVETDSPFLAPIPMRGRKNTPAYVIHTAKFVADLKGISLEQLC
EQTRINALKMFPKIQW
>Mature_256_residues
MEWIDIHAHLNMLEEGVEAAINNAKAVGVKKIITIGTQPEDHPIVLDIARKYYPEVYCTLGVHPHDGGTYTEAAGKFIEE
HVTEPCVVAVGEIGLDYYYDNSPRELQKEAFRAQLEIARRTKMPVEIHTRDAEEDTIEILKEFKGEVNGLIHCFTGTEWL
ARQALDVGFNISISGVVTFKSADSLRETVKMLPLDRIHVETDSPFLAPIPMRGRKNTPAYVIHTAKFVADLKGISLEQLC
EQTRINALKMFPKIQW

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=270, Percent_Identity=30, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI110349730, Length=270, Percent_Identity=29.6296296296296, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI226061853, Length=276, Percent_Identity=29.7101449275362, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI225903424, Length=203, Percent_Identity=33.4975369458128, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI226061614, Length=262, Percent_Identity=29.3893129770992, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI14042943, Length=202, Percent_Identity=27.2277227722772, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226061595, Length=230, Percent_Identity=27.8260869565217, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI225903439, Length=159, Percent_Identity=28.3018867924528, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=38.1322957198444, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI48994985, Length=231, Percent_Identity=33.7662337662338, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082439, Length=253, Percent_Identity=28.4584980237154, Blast_Score=114, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17559024, Length=215, Percent_Identity=33.0232558139535, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=29.3893129770992, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17543026, Length=232, Percent_Identity=29.7413793103448, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=218, Percent_Identity=30.2752293577982, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24648690, Length=279, Percent_Identity=30.4659498207885, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI221330018, Length=235, Percent_Identity=30.6382978723404, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24586117, Length=203, Percent_Identity=32.0197044334975, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28869; Mature: 28869

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWIDIHAHLNMLEEGVEAAINNAKAVGVKKIITIGTQPEDHPIVLDIARKYYPEVYCTL
CCEEEEHHHHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCEEEEEHHHHCCEEEEEE
GVHPHDGGTYTEAAGKFIEEHVTEPCVVAVGEIGLDYYYDNSPRELQKEAFRAQLEIARR
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHCEEEEECCCHHHHHHHHHHHHHHHHHH
TKMPVEIHTRDAEEDTIEILKEFKGEVNGLIHCFTGTEWLARQALDVGFNISISGVVTFK
CCCCEEEECCCCCHHHHHHHHHHCCHHCCEEEEECCHHHHHHHHHHCCCCEEEEEEEEEC
SADSLRETVKMLPLDRIHVETDSPFLAPIPMRGRKNTPAYVIHTAKFVADLKGISLEQLC
CHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCCCCCEEEEEHHHHHHHHCCCCHHHHH
EQTRINALKMFPKIQW
HHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEWIDIHAHLNMLEEGVEAAINNAKAVGVKKIITIGTQPEDHPIVLDIARKYYPEVYCTL
CCEEEEHHHHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCEEEEEHHHHCCEEEEEE
GVHPHDGGTYTEAAGKFIEEHVTEPCVVAVGEIGLDYYYDNSPRELQKEAFRAQLEIARR
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHCEEEEECCCHHHHHHHHHHHHHHHHHH
TKMPVEIHTRDAEEDTIEILKEFKGEVNGLIHCFTGTEWLARQALDVGFNISISGVVTFK
CCCCEEEECCCCCHHHHHHHHHHCCHHCCEEEEECCHHHHHHHHHHCCCCEEEEEEEEEC
SADSLRETVKMLPLDRIHVETDSPFLAPIPMRGRKNTPAYVIHTAKFVADLKGISLEQLC
CHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCCCCCEEEEEHHHHHHHHCCCCHHHHH
EQTRINALKMFPKIQW
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]