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The map label for this gene is prc [H]

Identifier: 42522531

GI number: 42522531

Start: 913566

End: 915587

Strand: Direct

Name: prc [H]

Synonym: Bd0967

Alternate gene names: 42522531

Gene position: 913566-915587 (Clockwise)

Preceding gene: 42522530

Following gene: 42522533

Centisome position: 24.15

GC content: 48.62

Gene sequence:

>2022_bases
ATGAGTTCATTCTCAAAAGGCGTTAGAGGTTTCATCATTGCCGGATCATTGGCAGTTTCATCTTTGGCATCGGCCCAACT
GAAAGAAGGCCTGGAGTGCCGTTACCTGACAGTGATTGAACAGGGCTTCCTTGCCAACCACGTGAAGTATTCCAACCGCG
ACACCGATCTGCAAAACCGTGTGATCGAACAGTATCTGAAACGCCTGGATCCTTCCAAAATCTATCTGACTCAAGGTGAT
GTCGATGCGATTCGCAAATCTGCGGGCAACGTTTTTGATAAAACCAAAAACCGTGACTGCTCGTTCCTGGATGCAGCTCA
GAAAATCGTTCTGGAGCGCGTGAAAGACCGTTCTGAATTTGCTAAAAAATATCTGGGCAAAGACTTCAAGTTTGAGTCTT
CCACAGAATTCACTTTTGATCCGGAAAAGAAAACCTGGCCGAAGGATTCTGCTGACGCCAATGAATATCTGAAAAAGTAT
ATCCAGTTCCAGATCGGGAACTACATGGCGACAGACATGAAAATGGATGAAGCCAAAAAGAACGTGATCAAAAACTATGA
GCGTGCAGTGAAAAGAACCGCTGACACCACCCAGGATGATCTGTTCTCTGGTTACCTGGATTCCTTTGCTCGCGCGTTGG
ATCCACACTCCAGCTTCTTCTCTCGCGATGTGCTAGAGGACTTCGAAATTCAGATGCGTTTGTCCTTGGAAGGTATCGGC
GCGACACTTTCTTCCCAGGATGGTTTCACAGTTGTGGAACAACTGGTTCCGGGCGGGGCGGCAGCGAAATCCGGCCTGAT
TGAGCCACAGGATAAAATCGTGGCTGTCGGTCAGGAAAAAGGCGCGATGGAAAATGTGATCGACATGGATTTGAAAGACG
TTGTCAAAAAAATCCGTGGTAACAAGGGCACGAAAGTGCGCCTGACTATTTTGAGAAAATCCGGTGAAGGCAAAAAACGT
TTTGATGTCACTTTGACCCGTGAAAAGGTGAACCTGGAGGACGAAGCAGCGTCCATCATCTATCAGGATCGTGAAATCAA
CGGTCAGAAAAAGAAAATCGGTGTTATCAACTTCCCATCCTTCTATGCGGATTCCCGTCGTGGCGGCAGATCTTCTGCGG
CTGACATGAAAAAGCTGATCAAGGAAGCCAACGAAAAGAAAGTCGACGGCCTGGTACTGGATCTTTCCAACAACGGTGGC
GGTTCTCTTGAAGATGCGGTGAAAATCGCGGGTCTGTTCTTCCAGACCGGGAACGTGGTGAAGCAGTCCTCCAAAAATGA
AGGCCGTGCGGAATCCGCACTTCGCGACACAGATCCAATGGTGGACTGGTCAGGTCCGCTGGTGGTATTGACCAGCCGTA
TCTCTGCTTCCGCTTCCGAGATTGTGTCTGGTACTTTGCAGGATTATAAACGTGCCGTTGTCGTGGGTGGTGATCACACT
TACGGTAAAGGTTCTGTTCAGTCCGTACTTCCAATTCCGAACAACCTGGGCGCGATCAAAGTGACTGTGGGTATGTTCTT
CGTGCCGGGTGGTAAATCCACTCAGCACCGTGGTGTGGATGCGGATATCGTTTTGCCAGGCCCGTTCAGTGCGGATGACA
TCGGCGAAAAATACATGGATTACTCTTTGCCGCCAAAAACGATTGAGTCCTTCCTGTCTCCGGATGCTTACGTGAAAGAA
GGCCCGGGCGCTTGGAAAGAGATCAAACCAGAGTGGCTGAAGTCCCTGCGTGAAAGATCCGGTGAGCGTGTTGCTAAGAA
TGATGAATTCAAAAAAATCGTTGAAGAGCTGAACAAAGCCAAAGCCCGCGGTAAAGTGATCCGCGTGAGCGAAGTTCTTA
AAGACAAGAACGAAAAAGAAAAGAAAGACAAAGCTAAAAAGACCGCTAGCAAGGCCAAGAAAAACGAAGAGTATTTGAAG
CGTCCTGACATCATGGAAGCGGAAAATGTTCTTCTGGATCTGATTCAGCTTGAGGACGGGAAATCCTTGGTGCCTCAGCA
GAAACAGGCCAACGCCAAGTAG

Upstream 100 bases:

>100_bases
ATTTATGACGTGCTTCATAAATTGAATGCTCTCAGCTAATTATTTGATAATCTAATGCAATTAGGACTGCTCCCGTTCGG
GGAGCCATGGAAGGATCAGC

Downstream 100 bases:

>100_bases
TGTGATTTGAGGAAACGTTTGTTGTTGTTGAAGCCCGGAGCCACAGTCTCCGGGCTTTTTTTATTTGTCTTCGCGAACAG
AAGTTCGGTCCAGAAATGTA

Product: tail-specific protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MSSFSKGVRGFIIAGSLAVSSLASAQLKEGLECRYLTVIEQGFLANHVKYSNRDTDLQNRVIEQYLKRLDPSKIYLTQGD
VDAIRKSAGNVFDKTKNRDCSFLDAAQKIVLERVKDRSEFAKKYLGKDFKFESSTEFTFDPEKKTWPKDSADANEYLKKY
IQFQIGNYMATDMKMDEAKKNVIKNYERAVKRTADTTQDDLFSGYLDSFARALDPHSSFFSRDVLEDFEIQMRLSLEGIG
ATLSSQDGFTVVEQLVPGGAAAKSGLIEPQDKIVAVGQEKGAMENVIDMDLKDVVKKIRGNKGTKVRLTILRKSGEGKKR
FDVTLTREKVNLEDEAASIIYQDREINGQKKKIGVINFPSFYADSRRGGRSSAADMKKLIKEANEKKVDGLVLDLSNNGG
GSLEDAVKIAGLFFQTGNVVKQSSKNEGRAESALRDTDPMVDWSGPLVVLTSRISASASEIVSGTLQDYKRAVVVGGDHT
YGKGSVQSVLPIPNNLGAIKVTVGMFFVPGGKSTQHRGVDADIVLPGPFSADDIGEKYMDYSLPPKTIESFLSPDAYVKE
GPGAWKEIKPEWLKSLRERSGERVAKNDEFKKIVEELNKAKARGKVIRVSEVLKDKNEKEKKDKAKKTASKAKKNEEYLK
RPDIMEAENVLLDLIQLEDGKSLVPQQKQANAK

Sequences:

>Translated_673_residues
MSSFSKGVRGFIIAGSLAVSSLASAQLKEGLECRYLTVIEQGFLANHVKYSNRDTDLQNRVIEQYLKRLDPSKIYLTQGD
VDAIRKSAGNVFDKTKNRDCSFLDAAQKIVLERVKDRSEFAKKYLGKDFKFESSTEFTFDPEKKTWPKDSADANEYLKKY
IQFQIGNYMATDMKMDEAKKNVIKNYERAVKRTADTTQDDLFSGYLDSFARALDPHSSFFSRDVLEDFEIQMRLSLEGIG
ATLSSQDGFTVVEQLVPGGAAAKSGLIEPQDKIVAVGQEKGAMENVIDMDLKDVVKKIRGNKGTKVRLTILRKSGEGKKR
FDVTLTREKVNLEDEAASIIYQDREINGQKKKIGVINFPSFYADSRRGGRSSAADMKKLIKEANEKKVDGLVLDLSNNGG
GSLEDAVKIAGLFFQTGNVVKQSSKNEGRAESALRDTDPMVDWSGPLVVLTSRISASASEIVSGTLQDYKRAVVVGGDHT
YGKGSVQSVLPIPNNLGAIKVTVGMFFVPGGKSTQHRGVDADIVLPGPFSADDIGEKYMDYSLPPKTIESFLSPDAYVKE
GPGAWKEIKPEWLKSLRERSGERVAKNDEFKKIVEELNKAKARGKVIRVSEVLKDKNEKEKKDKAKKTASKAKKNEEYLK
RPDIMEAENVLLDLIQLEDGKSLVPQQKQANAK
>Mature_672_residues
SSFSKGVRGFIIAGSLAVSSLASAQLKEGLECRYLTVIEQGFLANHVKYSNRDTDLQNRVIEQYLKRLDPSKIYLTQGDV
DAIRKSAGNVFDKTKNRDCSFLDAAQKIVLERVKDRSEFAKKYLGKDFKFESSTEFTFDPEKKTWPKDSADANEYLKKYI
QFQIGNYMATDMKMDEAKKNVIKNYERAVKRTADTTQDDLFSGYLDSFARALDPHSSFFSRDVLEDFEIQMRLSLEGIGA
TLSSQDGFTVVEQLVPGGAAAKSGLIEPQDKIVAVGQEKGAMENVIDMDLKDVVKKIRGNKGTKVRLTILRKSGEGKKRF
DVTLTREKVNLEDEAASIIYQDREINGQKKKIGVINFPSFYADSRRGGRSSAADMKKLIKEANEKKVDGLVLDLSNNGGG
SLEDAVKIAGLFFQTGNVVKQSSKNEGRAESALRDTDPMVDWSGPLVVLTSRISASASEIVSGTLQDYKRAVVVGGDHTY
GKGSVQSVLPIPNNLGAIKVTVGMFFVPGGKSTQHRGVDADIVLPGPFSADDIGEKYMDYSLPPKTIESFLSPDAYVKEG
PGAWKEIKPEWLKSLRERSGERVAKNDEFKKIVEELNKAKARGKVIRVSEVLKDKNEKEKKDKAKKTASKAKKNEEYLKR
PDIMEAENVLLDLIQLEDGKSLVPQQKQANAK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=697, Percent_Identity=32.9985652797704, Blast_Score=308, Evalue=6e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 74723; Mature: 74592

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFSKGVRGFIIAGSLAVSSLASAQLKEGLECRYLTVIEQGFLANHVKYSNRDTDLQNR
CCCHHHCCCEEEEECHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCHHHHH
VIEQYLKRLDPSKIYLTQGDVDAIRKSAGNVFDKTKNRDCSFLDAAQKIVLERVKDRSEF
HHHHHHHHCCCCEEEEECCCHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AKKYLGKDFKFESSTEFTFDPEKKTWPKDSADANEYLKKYIQFQIGNYMATDMKMDEAKK
HHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHHHH
NVIKNYERAVKRTADTTQDDLFSGYLDSFARALDPHSSFFSRDVLEDFEIQMRLSLEGIG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEEECC
ATLSSQDGFTVVEQLVPGGAAAKSGLIEPQDKIVAVGQEKGAMENVIDMDLKDVVKKIRG
CCCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCEEEECCCCCHHHHHHHCCHHHHHHHHCC
NKGTKVRLTILRKSGEGKKRFDVTLTREKVNLEDEAASIIYQDREINGQKKKIGVINFPS
CCCCEEEEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHEECCCCCCCCCEEEEEECCH
FYADSRRGGRSSAADMKKLIKEANEKKVDGLVLDLSNNGGGSLEDAVKIAGLFFQTGNVV
HHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHH
KQSSKNEGRAESALRDTDPMVDWSGPLVVLTSRISASASEIVSGTLQDYKRAVVVGGDHT
HHCCCCCCHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCEEEEECCCCC
YGKGSVQSVLPIPNNLGAIKVTVGMFFVPGGKSTQHRGVDADIVLPGPFSADDIGEKYMD
CCCCCCCEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHC
YSLPPKTIESFLSPDAYVKEGPGAWKEIKPEWLKSLRERSGERVAKNDEFKKIVEELNKA
CCCCHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
KARGKVIRVSEVLKDKNEKEKKDKAKKTASKAKKNEEYLKRPDIMEAENVLLDLIQLEDG
HHCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHCCCC
KSLVPQQKQANAK
CCCCCCCCCCCCC
>Mature Secondary Structure 
SSFSKGVRGFIIAGSLAVSSLASAQLKEGLECRYLTVIEQGFLANHVKYSNRDTDLQNR
CCHHHCCCEEEEECHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCHHHHH
VIEQYLKRLDPSKIYLTQGDVDAIRKSAGNVFDKTKNRDCSFLDAAQKIVLERVKDRSEF
HHHHHHHHCCCCEEEEECCCHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AKKYLGKDFKFESSTEFTFDPEKKTWPKDSADANEYLKKYIQFQIGNYMATDMKMDEAKK
HHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHHHH
NVIKNYERAVKRTADTTQDDLFSGYLDSFARALDPHSSFFSRDVLEDFEIQMRLSLEGIG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEEECC
ATLSSQDGFTVVEQLVPGGAAAKSGLIEPQDKIVAVGQEKGAMENVIDMDLKDVVKKIRG
CCCCCCCCHHHHHHHCCCCHHHHCCCCCCCCCEEEECCCCCHHHHHHHCCHHHHHHHHCC
NKGTKVRLTILRKSGEGKKRFDVTLTREKVNLEDEAASIIYQDREINGQKKKIGVINFPS
CCCCEEEEEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHEECCCCCCCCCEEEEEECCH
FYADSRRGGRSSAADMKKLIKEANEKKVDGLVLDLSNNGGGSLEDAVKIAGLFFQTGNVV
HHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCHHH
KQSSKNEGRAESALRDTDPMVDWSGPLVVLTSRISASASEIVSGTLQDYKRAVVVGGDHT
HHCCCCCCHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCEEEEECCCCC
YGKGSVQSVLPIPNNLGAIKVTVGMFFVPGGKSTQHRGVDADIVLPGPFSADDIGEKYMD
CCCCCCCEECCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHC
YSLPPKTIESFLSPDAYVKEGPGAWKEIKPEWLKSLRERSGERVAKNDEFKKIVEELNKA
CCCCHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
KARGKVIRVSEVLKDKNEKEKKDKAKKTASKAKKNEEYLKRPDIMEAENVLLDLIQLEDG
HHCCCEEEHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHCCCC
KSLVPQQKQANAK
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]