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The map label for this gene is tldD [C]

Identifier: 42522524

GI number: 42522524

Start: 904767

End: 906155

Strand: Direct

Name: tldD [C]

Synonym: Bd0958

Alternate gene names: 42522524

Gene position: 904767-906155 (Clockwise)

Preceding gene: 42522521

Following gene: 42522525

Centisome position: 23.92

GC content: 51.91

Gene sequence:

>1389_bases
ATGATTATTCAACCTCACATTCTGTCCAAGGCTCTGGATGCGGCTCTGAGCACGGGTGCTGATTTTGCCGATATCTTTGT
TGAAGATACGTATTCTTCCCAACTGACAGTTCTAAATTCCAAAGCCGACCAGGCCATCGTCGGCCAGTTGTACGGCGCAG
GAATTCGTTTGTTCTTCGGCCATGAGATTGTCTATGTGACGACGAATGATCTTTCGGAAGCAGGCCTGGTGAAGGCTGCG
TTGAACGCGGCTCAAAGCCGTGGCACAGGGGCCGCCTCCAAGTCCATGCCACTGATGCAGGTGCCTTTTGATTCTGTTCA
CACCTTTGGTGAAAAACCGTGGGAGATGAATCGCGACCGCAAGTTCAAATGGTTAAACGGCATTGATCAGCATGCCCGTG
CCCGCAACTCGGCGGTGACTCAGGTGGAAGCGGGTTTGAATGAAAAGTTCCAGCGTGTGCAAATCGCCAACTCTCGCGGT
TTGATGGCGTATGATGAACGGGCATATTCCCGTATCCGCATGCAGACTTTCGTTGAAAGCAACGGCGTGAAAGAAAGCTC
TGCCGATGACGAAGGTCACATGGGGACTTCGGAAGTTTATGATCAGATTGATTTGAAAGCTTTGGCAGAAGGTGCAGTGG
ACCGCGCGATGTTGTTGACCACGGCCGCCTATGCGCCAGCGGGTGACATGCCGGTATTGATCGACAATGCCTTCGGCGGT
GTCTTGTTCCACGAAGCCTGTGGTCACGGTCTGGAAACGACCGGTGTTGCCAAGGATTCTTCCGTGTTCTGCGGCAAGAT
GAATCAGAAAATCGCGCACGAATGTGTGACGGCGATTGATGATGGCACCATCGAAAACGGATGGGGCTCTTTGAACATGG
ATGACGAAGGCAACAAAACCAAGAAAACAACATTGATCGAAAACGGTGTCCTGAAATCCTACATCGTGGATGAAATGGGT
TCCCGTCAGACCGGTTATGAAATCACCGGCAGCGGTCGCCGTCAGTCTTACAAATATGCTCCGGCTTCCCGCATGAGAAA
CACATTCATCGCGGCTGGTAAAGACAAGTTCGAAGACATGGTTCGTGATGTGGACTACGGCCTTTATGCAAAACGCATGG
GTGGTGGTTCCGTGAATCCGGGCACAGGCGATTACAACTTCCAGGTGGCTGAAGGTTACATTATCCGTAATGGCCGCATC
GAAGAAGCGGTGAAGGGTGCCTGCCTGATCGGTCGTGGGATCGATACACTGGGTAAGATCACCAAAGTTTCTGATGATCT
GAAACTGGCGCGTGGTATGTGCGGATCTGTCAGTGGAACAATTCCGGCGGCTGTGGGTCAGCCTCAAGTTCTGGTTTCCA
GCCTGATGGTTGGTGGGAGAGCAAAATAA

Upstream 100 bases:

>100_bases
TACCGGATCATTTCTTCGGGGCTCTGACGCGACCTCCGGGGATTTCCCCTTGGGAGGGGGGAGGACTTGAGCTATCCTTT
GAAGATCTTAAGGAGGCCCT

Downstream 100 bases:

>100_bases
TGGACACTATTAAATCAAACTTCCAAAAGATCGCAGACCAGGCCCGTAAAGACGGTGCCAAAGTCGAAATGCTGGTGACC
GGTGGCGAAGCCCTGAGCAT

Product: putative Zn-dependent protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MIIQPHILSKALDAALSTGADFADIFVEDTYSSQLTVLNSKADQAIVGQLYGAGIRLFFGHEIVYVTTNDLSEAGLVKAA
LNAAQSRGTGAASKSMPLMQVPFDSVHTFGEKPWEMNRDRKFKWLNGIDQHARARNSAVTQVEAGLNEKFQRVQIANSRG
LMAYDERAYSRIRMQTFVESNGVKESSADDEGHMGTSEVYDQIDLKALAEGAVDRAMLLTTAAYAPAGDMPVLIDNAFGG
VLFHEACGHGLETTGVAKDSSVFCGKMNQKIAHECVTAIDDGTIENGWGSLNMDDEGNKTKKTTLIENGVLKSYIVDEMG
SRQTGYEITGSGRRQSYKYAPASRMRNTFIAAGKDKFEDMVRDVDYGLYAKRMGGGSVNPGTGDYNFQVAEGYIIRNGRI
EEAVKGACLIGRGIDTLGKITKVSDDLKLARGMCGSVSGTIPAAVGQPQVLVSSLMVGGRAK

Sequences:

>Translated_462_residues
MIIQPHILSKALDAALSTGADFADIFVEDTYSSQLTVLNSKADQAIVGQLYGAGIRLFFGHEIVYVTTNDLSEAGLVKAA
LNAAQSRGTGAASKSMPLMQVPFDSVHTFGEKPWEMNRDRKFKWLNGIDQHARARNSAVTQVEAGLNEKFQRVQIANSRG
LMAYDERAYSRIRMQTFVESNGVKESSADDEGHMGTSEVYDQIDLKALAEGAVDRAMLLTTAAYAPAGDMPVLIDNAFGG
VLFHEACGHGLETTGVAKDSSVFCGKMNQKIAHECVTAIDDGTIENGWGSLNMDDEGNKTKKTTLIENGVLKSYIVDEMG
SRQTGYEITGSGRRQSYKYAPASRMRNTFIAAGKDKFEDMVRDVDYGLYAKRMGGGSVNPGTGDYNFQVAEGYIIRNGRI
EEAVKGACLIGRGIDTLGKITKVSDDLKLARGMCGSVSGTIPAAVGQPQVLVSSLMVGGRAK
>Mature_462_residues
MIIQPHILSKALDAALSTGADFADIFVEDTYSSQLTVLNSKADQAIVGQLYGAGIRLFFGHEIVYVTTNDLSEAGLVKAA
LNAAQSRGTGAASKSMPLMQVPFDSVHTFGEKPWEMNRDRKFKWLNGIDQHARARNSAVTQVEAGLNEKFQRVQIANSRG
LMAYDERAYSRIRMQTFVESNGVKESSADDEGHMGTSEVYDQIDLKALAEGAVDRAMLLTTAAYAPAGDMPVLIDNAFGG
VLFHEACGHGLETTGVAKDSSVFCGKMNQKIAHECVTAIDDGTIENGWGSLNMDDEGNKTKKTTLIENGVLKSYIVDEMG
SRQTGYEITGSGRRQSYKYAPASRMRNTFIAAGKDKFEDMVRDVDYGLYAKRMGGGSVNPGTGDYNFQVAEGYIIRNGRI
EEAVKGACLIGRGIDTLGKITKVSDDLKLARGMCGSVSGTIPAAVGQPQVLVSSLMVGGRAK

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=448, Percent_Identity=33.7053571428571, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1790682, Length=450, Percent_Identity=22.6666666666667, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49769; Mature: 49769

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIQPHILSKALDAALSTGADFADIFVEDTYSSQLTVLNSKADQAIVGQLYGAGIRLFFG
CCCCCHHHHHHHHHHHHCCCCCEEHEEECCCCCEEEEEECCCCHHHHHHHHCCCEEEEEC
HEIVYVTTNDLSEAGLVKAALNAAQSRGTGAASKSMPLMQVPFDSVHTFGEKPWEMNRDR
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHCCCCCCCCCCCC
KFKWLNGIDQHARARNSAVTQVEAGLNEKFQRVQIANSRGLMAYDERAYSRIRMQTFVES
CCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEHHHHHHHHHHHHHHHH
NGVKESSADDEGHMGTSEVYDQIDLKALAEGAVDRAMLLTTAAYAPAGDMPVLIDNAFGG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCH
VLFHEACGHGLETTGVAKDSSVFCGKMNQKIAHECVTAIDDGTIENGWGSLNMDDEGNKT
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
KKTTLIENGVLKSYIVDEMGSRQTGYEITGSGRRQSYKYAPASRMRNTFIAAGKDKFEDM
HHHHHHHCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHEEECCHHHHHHH
VRDVDYGLYAKRMGGGSVNPGTGDYNFQVAEGYIIRNGRIEEAVKGACLIGRGIDTLGKI
HHHCCCCHHHHHCCCCCCCCCCCCCEEEEECCEEEECCCHHHHHCCCEEECCCHHHHHHH
TKVSDDLKLARGMCGSVSGTIPAAVGQPQVLVSSLMVGGRAK
HHCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIIQPHILSKALDAALSTGADFADIFVEDTYSSQLTVLNSKADQAIVGQLYGAGIRLFFG
CCCCCHHHHHHHHHHHHCCCCCEEHEEECCCCCEEEEEECCCCHHHHHHHHCCCEEEEEC
HEIVYVTTNDLSEAGLVKAALNAAQSRGTGAASKSMPLMQVPFDSVHTFGEKPWEMNRDR
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHCCCCCCCCCCCC
KFKWLNGIDQHARARNSAVTQVEAGLNEKFQRVQIANSRGLMAYDERAYSRIRMQTFVES
CCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEHHHHHHHHHHHHHHHH
NGVKESSADDEGHMGTSEVYDQIDLKALAEGAVDRAMLLTTAAYAPAGDMPVLIDNAFGG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCH
VLFHEACGHGLETTGVAKDSSVFCGKMNQKIAHECVTAIDDGTIENGWGSLNMDDEGNKT
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
KKTTLIENGVLKSYIVDEMGSRQTGYEITGSGRRQSYKYAPASRMRNTFIAAGKDKFEDM
HHHHHHHCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHEEECCHHHHHHH
VRDVDYGLYAKRMGGGSVNPGTGDYNFQVAEGYIIRNGRIEEAVKGACLIGRGIDTLGKI
HHHCCCCHHHHHCCCCCCCCCCCCCEEEEECCEEEECCCHHHHHCCCEEECCCHHHHHHH
TKVSDDLKLARGMCGSVSGTIPAAVGQPQVLVSSLMVGGRAK
HHCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]