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The map label for this gene is pmbA [C]

Identifier: 42522525

GI number: 42522525

Start: 906155

End: 907498

Strand: Direct

Name: pmbA [C]

Synonym: Bd0959

Alternate gene names: 42522525

Gene position: 906155-907498 (Clockwise)

Preceding gene: 42522524

Following gene: 42522526

Centisome position: 23.95

GC content: 50.6

Gene sequence:

>1344_bases
ATGGACACTATTAAATCAAACTTCCAAAAGATCGCAGACCAGGCCCGTAAAGACGGTGCCAAAGTCGAAATGCTGGTGAC
CGGTGGCGAAGCCCTGAGCATCGGTTATTCCAAACGCAAACTGGAATCCTTCGAGTCCACACAGACCCAGATGGCCGGCT
TGCGTGTGATTCTTGGTGCGAACCAGGGATATGCTTACACCGAAAATCTTTCTGAAGAATCCCTGCTGCGCACTTACGGT
GAGGCTTTGAATAATGCCAAGACCGTGCAGACGGGTGAAACAAAGCCTGTCGAGCTGGTGAAGCCTCAGGCCGTGAAAGC
GATGCCGGAGCTGTTCAAGCCGGAAGAAATCGCCATGGAAAAAAAGCTGGAAGTGGCAAGACTTCTGGAAGAGCTGTGTC
TGGCGAAAGATTCCCGCGTGACGAATGTGCCTTACTCCGGATTCAATGAATCTGTGGTGTTTAAGCGCATTTTGAATTCG
GAAGGTCTGGATCAGGAATTCAAACAGAATTACTACAGTGGTTACACGTACCCGCTGGCAAAAGACGGTGAGAATTCCAA
AATGGATGGCGAAGGTTTCTTTGCCCGCAAGTTTGATGACATCAACACCGCAGAAGTGACGGGTGAAGGTGTGCGTAAGG
CCCTGGCTCGTTTGGGTGCGACTCAGCTTCCGACTGGGAACTATGCTGTGGTGATCGACCGTGAGCAGTTCCCGACGGTT
TTGCAGATGATCCATGACTATTTCTCTGCAAAAGAAGTTCACGAAGGAAAGTCCCTGTTCAAAGGCAAGCTGGGTCAGAA
GATCGCCAGCGACAAGTTTGAGCTGATTGATGATCCGTTTGAAACCCGTGGCACAGCGGTTCGTCCGTTTGATGATGAAG
GTGCGCCTTCTCAGAAAACCGTGCTGTTTGATAAAGGTGTTTTGAAAAACTATCTGTCCAATCTGGAATACGCCAACAAG
ATGAATCTGCCGCACACGGCGCATGCCAGCCGTGGGCCCGCCTCTCAACAGGCGATTGCACCAACTAATATGGTTGTCGC
AACCGGGGATAAGTCTTTGCAGGAACTGCTGGCTGCCTATGACAAGGTCATTCACCTTGCTGGGTTTGAGGGCGGTCTGC
ACGCGGGCTTTAAACAGTCCACGGGGGACTTCTCGATGCCGGCTTCTGGCTTCTTGTATGAAAAAGGCCAGAACAAAGGG
CCGATTGAACAGTTTGTGATGTCCGGAAACGTGCTGGAACTGCTTCGTGATATCGAGGCGGTGGGGCGCGACTATAACAA
ACCAGGCAATTCCTTTATTTGTCCGGATGTATTGATCAAATCTTTGAGTTTTGCAGGAGCATAA

Upstream 100 bases:

>100_bases
CGCGTGGTATGTGCGGATCTGTCAGTGGAACAATTCCGGCGGCTGTGGGTCAGCCTCAAGTTCTGGTTTCCAGCCTGATG
GTTGGTGGGAGAGCAAAATA

Downstream 100 bases:

>100_bases
GATGAAGAAGTTCGCACTTATTACGACGTTGTTGTTTCAGATGGTGATAAGTGCGGGCTGCTCCAGCATGTTTGGTTATG
CTGAAGAACCGAAAGTTCAG

Product: putative inactivated Zn-dependent peptidase, PMBA ortholog

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MDTIKSNFQKIADQARKDGAKVEMLVTGGEALSIGYSKRKLESFESTQTQMAGLRVILGANQGYAYTENLSEESLLRTYG
EALNNAKTVQTGETKPVELVKPQAVKAMPELFKPEEIAMEKKLEVARLLEELCLAKDSRVTNVPYSGFNESVVFKRILNS
EGLDQEFKQNYYSGYTYPLAKDGENSKMDGEGFFARKFDDINTAEVTGEGVRKALARLGATQLPTGNYAVVIDREQFPTV
LQMIHDYFSAKEVHEGKSLFKGKLGQKIASDKFELIDDPFETRGTAVRPFDDEGAPSQKTVLFDKGVLKNYLSNLEYANK
MNLPHTAHASRGPASQQAIAPTNMVVATGDKSLQELLAAYDKVIHLAGFEGGLHAGFKQSTGDFSMPASGFLYEKGQNKG
PIEQFVMSGNVLELLRDIEAVGRDYNKPGNSFICPDVLIKSLSFAGA

Sequences:

>Translated_447_residues
MDTIKSNFQKIADQARKDGAKVEMLVTGGEALSIGYSKRKLESFESTQTQMAGLRVILGANQGYAYTENLSEESLLRTYG
EALNNAKTVQTGETKPVELVKPQAVKAMPELFKPEEIAMEKKLEVARLLEELCLAKDSRVTNVPYSGFNESVVFKRILNS
EGLDQEFKQNYYSGYTYPLAKDGENSKMDGEGFFARKFDDINTAEVTGEGVRKALARLGATQLPTGNYAVVIDREQFPTV
LQMIHDYFSAKEVHEGKSLFKGKLGQKIASDKFELIDDPFETRGTAVRPFDDEGAPSQKTVLFDKGVLKNYLSNLEYANK
MNLPHTAHASRGPASQQAIAPTNMVVATGDKSLQELLAAYDKVIHLAGFEGGLHAGFKQSTGDFSMPASGFLYEKGQNKG
PIEQFVMSGNVLELLRDIEAVGRDYNKPGNSFICPDVLIKSLSFAGA
>Mature_447_residues
MDTIKSNFQKIADQARKDGAKVEMLVTGGEALSIGYSKRKLESFESTQTQMAGLRVILGANQGYAYTENLSEESLLRTYG
EALNNAKTVQTGETKPVELVKPQAVKAMPELFKPEEIAMEKKLEVARLLEELCLAKDSRVTNVPYSGFNESVVFKRILNS
EGLDQEFKQNYYSGYTYPLAKDGENSKMDGEGFFARKFDDINTAEVTGEGVRKALARLGATQLPTGNYAVVIDREQFPTV
LQMIHDYFSAKEVHEGKSLFKGKLGQKIASDKFELIDDPFETRGTAVRPFDDEGAPSQKTVLFDKGVLKNYLSNLEYANK
MNLPHTAHASRGPASQQAIAPTNMVVATGDKSLQELLAAYDKVIHLAGFEGGLHAGFKQSTGDFSMPASGFLYEKGQNKG
PIEQFVMSGNVLELLRDIEAVGRDYNKPGNSFICPDVLIKSLSFAGA

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790682, Length=436, Percent_Identity=25.2293577981651, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789640, Length=404, Percent_Identity=24.5049504950495, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49143; Mature: 49143

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTIKSNFQKIADQARKDGAKVEMLVTGGEALSIGYSKRKLESFESTQTQMAGLRVILGA
CCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCCHHHHHHHHHHHHHHHHCEEEEEEC
NQGYAYTENLSEESLLRTYGEALNNAKTVQTGETKPVELVKPQAVKAMPELFKPEEIAME
CCCCEECCCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHCCCHHHHHHHHHCCCHHHHHH
KKLEVARLLEELCLAKDSRVTNVPYSGFNESVVFKRILNSEGLDQEFKQNYYSGYTYPLA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCC
KDGENSKMDGEGFFARKFDDINTAEVTGEGVRKALARLGATQLPTGNYAVVIDREQFPTV
CCCCCCCCCCCCCEEECCCCCCHHHHCHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHH
LQMIHDYFSAKEVHEGKSLFKGKLGQKIASDKFELIDDPFETRGTAVRPFDDEGAPSQKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHCCCCEECCCCCCCCCCCCE
VLFDKGVLKNYLSNLEYANKMNLPHTAHASRGPASQQAIAPTNMVVATGDKSLQELLAAY
EEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHH
DKVIHLAGFEGGLHAGFKQSTGDFSMPASGFLYEKGQNKGPIEQFVMSGNVLELLRDIEA
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHCCCHHHHHHHHHH
VGRDYNKPGNSFICPDVLIKSLSFAGA
HCCCCCCCCCCEECHHHHHHHHHHCCC
>Mature Secondary Structure
MDTIKSNFQKIADQARKDGAKVEMLVTGGEALSIGYSKRKLESFESTQTQMAGLRVILGA
CCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEECCCHHHHHHHHHHHHHHHHCEEEEEEC
NQGYAYTENLSEESLLRTYGEALNNAKTVQTGETKPVELVKPQAVKAMPELFKPEEIAME
CCCCEECCCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHCCCHHHHHHHHHCCCHHHHHH
KKLEVARLLEELCLAKDSRVTNVPYSGFNESVVFKRILNSEGLDQEFKQNYYSGYTYPLA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCC
KDGENSKMDGEGFFARKFDDINTAEVTGEGVRKALARLGATQLPTGNYAVVIDREQFPTV
CCCCCCCCCCCCCEEECCCCCCHHHHCHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHH
LQMIHDYFSAKEVHEGKSLFKGKLGQKIASDKFELIDDPFETRGTAVRPFDDEGAPSQKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHCCCCEECCCCCCCCCCCCE
VLFDKGVLKNYLSNLEYANKMNLPHTAHASRGPASQQAIAPTNMVVATGDKSLQELLAAY
EEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHH
DKVIHLAGFEGGLHAGFKQSTGDFSMPASGFLYEKGQNKGPIEQFVMSGNVLELLRDIEA
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHCCCHHHHHHHHHH
VGRDYNKPGNSFICPDVLIKSLSFAGA
HCCCCCCCCCCEECHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]