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The map label for this gene is ctaD [H]

Identifier: 42521910

GI number: 42521910

Start: 272574

End: 274181

Strand: Direct

Name: ctaD [H]

Synonym: Bd0287

Alternate gene names: 42521910

Gene position: 272574-274181 (Clockwise)

Preceding gene: 42521909

Following gene: 42521911

Centisome position: 7.21

GC content: 49.19

Gene sequence:

>1608_bases
ATGGCGAAAACTACAGCTCACGGCGACAACTATATTAATTTTGAAAAAGGCATCTGGTCCTGGCTGACTACTGTCGATCA
CAAACGTATCGGTTTGATGTACTTCATCACTGTTATGTTCTTCTTCTTCATCGGTGGGGTTATGGCCCTGTTGCTTCGTT
TGGAACTTTTTGCTCCAAATGCGGCTCCAAACGTGGGTCAGATCCTGGCTAACGGTGACGTTTACAATCAGGTGATGACA
TATCACGGGGCGATCATGGTCTTCATGGTTATCGTTCCTGGTATCCCTGCGATCCTGGGTAACTTCTTCCTGCCTTTGCA
AATCGGCGCGAAGGACGTGGCCTTCCCAAGAATCAACCTGCTAAGCTGGTACTGCTTCATGGCGGGTGCGATCCTGGCGA
TTGCAACTTTCTTCACTACTAAAATCGACACTGGCTGGACGTTCTACACTCCATACTCTATCAGAACGGGTACAGCGACA
GCGATGATGGTTCTTGCAGCCTTCATCATGGGTATGTCCTCCATCCTGACGGGTCTGAACTTCATCGTGACCGTGCACAA
ACTAAGAGCTCCTGGCATGACCATGCACAGAATGCCTTTGTTCATCTGGTCTTTGTATGCAACAGCGATCCTTCAGATGC
TGGCGACTCCGGTTCTGGGTATCACATTGCTTCTTTTGGCGGTGGAAAGATTCCTAGGTATCGGTATCTTCGATCCTAAA
CTGGGTGGTGACCCGGTATTGTTCCAGCACTTCTTCTGGTTCTACTCTCACCCTGCGGTTTACATCATGATCATCCCGGC
AATGGGTATCATCTCTGAGCTGATCACGACCTTCTCCAAAAAAGTCATCTTCGGTTACACGGCGATTGCATACTCTTCTT
TGGGTATCGCGGCTGTATCCTTCTTTGTTTGGGGTCACCACATGTTCGTGTCCGGTCAGTCTGAAACGACCGGCATCATC
TTCTCCTTCCTGACAATGCTGGTAGGGGTTCCGACGGCGATCAAGATGTTCAACTGGGTTGCGACCTTCTATAAAGGTTC
CGTGTCCTTCCAGTCTCCGATGCTTTATGCTTTGGGCTTCATGTTCCTGTTCGCCATCGGTGGTGTGACTGGGGTTATGC
TTGCGACTTTGCCAATCGACGTACACTTCCACGACACTTACTTCGTGGTAGCTCACTTCCACTATGTGATGGTGGGTGGT
ACTTTGATGGCATTGATGGGCGGCTACTTCTACTGGTTCCCGAAAATGTTCGGTAAGATGTACAACGAAACCACAGCTCG
TATTTCTTTCGTGTTCATCTTCATCGGTTTCAACGTGACCTTCTTCCCTCAGTTCGTTCTGGGCGCGATGGGTATGCCTC
GTCGTTACTTCGACTACATCCCGGCGTACGAGAACCTGAATAAGATCTCCACAGTGGGTTCTTGGTTGATCCTTATCGGC
TTCCTGTTCGGTCTTTACACAATCGTTCAGGGTCTGTTGAAAGGTGAAAAAGCTCCGATGAATCCTTGGGGCTCTAAAAC
TTTGGAGTGGCAGACGGCTTCTCCTCCTCCACATGACAACTTCAGTGTTGAACCAGTAGTAACAGCGGGGCCTTATGAGT
ACAGATAA

Upstream 100 bases:

>100_bases
TTCCCTAAGGGCGTTATGCCCACCTTCCAGGGTCAGCTGAACGAAAACGAATTGAGTGCTCTTGTCGAGTACATCAAGAA
TCTGAAGTAAGGAGTTGAGC

Downstream 100 bases:

>100_bases
TACAGCACACGGCGCTCACACAGCACACGTAGCTCACCACTTTAAAACGGCTGAGCAACAGTATTCCTCTGGTAAAGAGG
GTATCTGGTTGTTCATGCTT

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MAKTTAHGDNYINFEKGIWSWLTTVDHKRIGLMYFITVMFFFFIGGVMALLLRLELFAPNAAPNVGQILANGDVYNQVMT
YHGAIMVFMVIVPGIPAILGNFFLPLQIGAKDVAFPRINLLSWYCFMAGAILAIATFFTTKIDTGWTFYTPYSIRTGTAT
AMMVLAAFIMGMSSILTGLNFIVTVHKLRAPGMTMHRMPLFIWSLYATAILQMLATPVLGITLLLLAVERFLGIGIFDPK
LGGDPVLFQHFFWFYSHPAVYIMIIPAMGIISELITTFSKKVIFGYTAIAYSSLGIAAVSFFVWGHHMFVSGQSETTGII
FSFLTMLVGVPTAIKMFNWVATFYKGSVSFQSPMLYALGFMFLFAIGGVTGVMLATLPIDVHFHDTYFVVAHFHYVMVGG
TLMALMGGYFYWFPKMFGKMYNETTARISFVFIFIGFNVTFFPQFVLGAMGMPRRYFDYIPAYENLNKISTVGSWLILIG
FLFGLYTIVQGLLKGEKAPMNPWGSKTLEWQTASPPPHDNFSVEPVVTAGPYEYR

Sequences:

>Translated_535_residues
MAKTTAHGDNYINFEKGIWSWLTTVDHKRIGLMYFITVMFFFFIGGVMALLLRLELFAPNAAPNVGQILANGDVYNQVMT
YHGAIMVFMVIVPGIPAILGNFFLPLQIGAKDVAFPRINLLSWYCFMAGAILAIATFFTTKIDTGWTFYTPYSIRTGTAT
AMMVLAAFIMGMSSILTGLNFIVTVHKLRAPGMTMHRMPLFIWSLYATAILQMLATPVLGITLLLLAVERFLGIGIFDPK
LGGDPVLFQHFFWFYSHPAVYIMIIPAMGIISELITTFSKKVIFGYTAIAYSSLGIAAVSFFVWGHHMFVSGQSETTGII
FSFLTMLVGVPTAIKMFNWVATFYKGSVSFQSPMLYALGFMFLFAIGGVTGVMLATLPIDVHFHDTYFVVAHFHYVMVGG
TLMALMGGYFYWFPKMFGKMYNETTARISFVFIFIGFNVTFFPQFVLGAMGMPRRYFDYIPAYENLNKISTVGSWLILIG
FLFGLYTIVQGLLKGEKAPMNPWGSKTLEWQTASPPPHDNFSVEPVVTAGPYEYR
>Mature_534_residues
AKTTAHGDNYINFEKGIWSWLTTVDHKRIGLMYFITVMFFFFIGGVMALLLRLELFAPNAAPNVGQILANGDVYNQVMTY
HGAIMVFMVIVPGIPAILGNFFLPLQIGAKDVAFPRINLLSWYCFMAGAILAIATFFTTKIDTGWTFYTPYSIRTGTATA
MMVLAAFIMGMSSILTGLNFIVTVHKLRAPGMTMHRMPLFIWSLYATAILQMLATPVLGITLLLLAVERFLGIGIFDPKL
GGDPVLFQHFFWFYSHPAVYIMIIPAMGIISELITTFSKKVIFGYTAIAYSSLGIAAVSFFVWGHHMFVSGQSETTGIIF
SFLTMLVGVPTAIKMFNWVATFYKGSVSFQSPMLYALGFMFLFAIGGVTGVMLATLPIDVHFHDTYFVVAHFHYVMVGGT
LMALMGGYFYWFPKMFGKMYNETTARISFVFIFIGFNVTFFPQFVLGAMGMPRRYFDYIPAYENLNKISTVGSWLILIGF
LFGLYTIVQGLLKGEKAPMNPWGSKTLEWQTASPPPHDNFSVEPVVTAGPYEYR

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=511, Percent_Identity=40.1174168297456, Blast_Score=374, Evalue=1e-103,
Organism=Escherichia coli, GI1786634, Length=516, Percent_Identity=38.7596899224806, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6226519, Length=537, Percent_Identity=40.0372439478585, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6226524, Length=329, Percent_Identity=39.8176291793313, Blast_Score=238, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6226523, Length=255, Percent_Identity=37.6470588235294, Blast_Score=147, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 59827; Mature: 59696

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTTAHGDNYINFEKGIWSWLTTVDHKRIGLMYFITVMFFFFIGGVMALLLRLELFAPN
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AAPNVGQILANGDVYNQVMTYHGAIMVFMVIVPGIPAILGNFFLPLQIGAKDVAFPRINL
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCCHHHH
LSWYCFMAGAILAIATFFTTKIDTGWTFYTPYSIRTGTATAMMVLAAFIMGMSSILTGLN
HHHHHHHHHHHHHHHHHHHHEECCCEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHH
FIVTVHKLRAPGMTMHRMPLFIWSLYATAILQMLATPVLGITLLLLAVERFLGIGIFDPK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LGGDPVLFQHFFWFYSHPAVYIMIIPAMGIISELITTFSKKVIFGYTAIAYSSLGIAAVS
CCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVWGHHMFVSGQSETTGIIFSFLTMLVGVPTAIKMFNWVATFYKGSVSFQSPMLYALGF
HHHHHCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
MFLFAIGGVTGVMLATLPIDVHFHDTYFVVAHFHYVMVGGTLMALMGGYFYWFPKMFGKM
HHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNETTARISFVFIFIGFNVTFFPQFVLGAMGMPRRYFDYIPAYENLNKISTVGSWLILIG
HCCHHHHHEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
FLFGLYTIVQGLLKGEKAPMNPWGSKTLEWQTASPPPHDNFSVEPVVTAGPYEYR
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
AKTTAHGDNYINFEKGIWSWLTTVDHKRIGLMYFITVMFFFFIGGVMALLLRLELFAPN
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AAPNVGQILANGDVYNQVMTYHGAIMVFMVIVPGIPAILGNFFLPLQIGAKDVAFPRINL
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCCHHHH
LSWYCFMAGAILAIATFFTTKIDTGWTFYTPYSIRTGTATAMMVLAAFIMGMSSILTGLN
HHHHHHHHHHHHHHHHHHHHEECCCEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHH
FIVTVHKLRAPGMTMHRMPLFIWSLYATAILQMLATPVLGITLLLLAVERFLGIGIFDPK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LGGDPVLFQHFFWFYSHPAVYIMIIPAMGIISELITTFSKKVIFGYTAIAYSSLGIAAVS
CCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVWGHHMFVSGQSETTGIIFSFLTMLVGVPTAIKMFNWVATFYKGSVSFQSPMLYALGF
HHHHHCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
MFLFAIGGVTGVMLATLPIDVHFHDTYFVVAHFHYVMVGGTLMALMGGYFYWFPKMFGKM
HHHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNETTARISFVFIFIGFNVTFFPQFVLGAMGMPRRYFDYIPAYENLNKISTVGSWLILIG
HCCHHHHHEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
FLFGLYTIVQGLLKGEKAPMNPWGSKTLEWQTASPPPHDNFSVEPVVTAGPYEYR
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]