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The map label for this gene is ctaE [H]

Identifier: 42521911

GI number: 42521911

Start: 274168

End: 274833

Strand: Direct

Name: ctaE [H]

Synonym: Bd0288

Alternate gene names: 42521911

Gene position: 274168-274833 (Clockwise)

Preceding gene: 42521910

Following gene: 42521912

Centisome position: 7.25

GC content: 48.95

Gene sequence:

>666_bases
ATGAGTACAGATAATACAGCACACGGCGCTCACACAGCACACGTAGCTCACCACTTTAAAACGGCTGAGCAACAGTATTC
CTCTGGTAAAGAGGGTATCTGGTTGTTCATGCTTACAGAGATCCTGATGTTCGGTGCGATCTTTGTGGGTTACGCTCTTT
ATCACAATGAATATCCGGCGATGTTCGCTGAAGGTGCGAAGTCTCTTGATTGGAAGATGGGTTTCGTAAATACCCTGGTT
CTGATCTTCTCGTCCTTCACTATGGCGATCTCGATCTCCTTCATCCAGAAGAACCAGCAGAAAAAAGCGGTCCTTGCCCT
GGCAACGACTGTACTTTGCGGCGCGATCTTCATGGTGATCAAGTACTTCGAATACCAGCATAAATTCCACCTGGGTCTGT
TCCCGGGTAAATTCCTGGATGTTGCGAAAGTGGGCGCAGAACACGCAAACCTTGGTTTGTACTTCGGCTTCTACTACGTG
ATGACGGGCCTGCACGGTATCCACGTCTTGTTGGGTATGGGTCTGATCACCTGGTGTTTGATCCGCACAATGCGCGGTGA
TTTCCACAGTCAGTACTGGATCGTGGTAGAGGGTGTTGGTTTGTTCTGGCACATCGTCGACTTGATCTGGATCTTCCTAT
TCCCTCTTCTGTATTTGGTGGGGTAA

Upstream 100 bases:

>100_bases
CCGATGAATCCTTGGGGCTCTAAAACTTTGGAGTGGCAGACGGCTTCTCCTCCTCCACATGACAACTTCAGTGTTGAACC
AGTAGTAACAGCGGGGCCTT

Downstream 100 bases:

>100_bases
CAAATGGCTCAACATAACGACAGTAATTCGAATGTTCTTCATCCGCACATCACGCCACTGGCAACTTACTTCAAAGTTGC
CCTGGCTTTGTTCGGTCTGA

Product: cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSTDNTAHGAHTAHVAHHFKTAEQQYSSGKEGIWLFMLTEILMFGAIFVGYALYHNEYPAMFAEGAKSLDWKMGFVNTLV
LIFSSFTMAISISFIQKNQQKKAVLALATTVLCGAIFMVIKYFEYQHKFHLGLFPGKFLDVAKVGAEHANLGLYFGFYYV
MTGLHGIHVLLGMGLITWCLIRTMRGDFHSQYWIVVEGVGLFWHIVDLIWIFLFPLLYLVG

Sequences:

>Translated_221_residues
MSTDNTAHGAHTAHVAHHFKTAEQQYSSGKEGIWLFMLTEILMFGAIFVGYALYHNEYPAMFAEGAKSLDWKMGFVNTLV
LIFSSFTMAISISFIQKNQQKKAVLALATTVLCGAIFMVIKYFEYQHKFHLGLFPGKFLDVAKVGAEHANLGLYFGFYYV
MTGLHGIHVLLGMGLITWCLIRTMRGDFHSQYWIVVEGVGLFWHIVDLIWIFLFPLLYLVG
>Mature_220_residues
STDNTAHGAHTAHVAHHFKTAEQQYSSGKEGIWLFMLTEILMFGAIFVGYALYHNEYPAMFAEGAKSLDWKMGFVNTLVL
IFSSFTMAISISFIQKNQQKKAVLALATTVLCGAIFMVIKYFEYQHKFHLGLFPGKFLDVAKVGAEHANLGLYFGFYYVM
TGLHGIHVLLGMGLITWCLIRTMRGDFHSQYWIVVEGVGLFWHIVDLIWIFLFPLLYLVG

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=150, Percent_Identity=28, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786633, Length=222, Percent_Identity=25.2252252252252, Blast_Score=77, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 25078; Mature: 24947

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDNTAHGAHTAHVAHHFKTAEQQYSSGKEGIWLFMLTEILMFGAIFVGYALYHNEYPA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
MFAEGAKSLDWKMGFVNTLVLIFSSFTMAISISFIQKNQQKKAVLALATTVLCGAIFMVI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
KYFEYQHKFHLGLFPGKFLDVAKVGAEHANLGLYFGFYYVMTGLHGIHVLLGMGLITWCL
HHHHHHHHEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRTMRGDFHSQYWIVVEGVGLFWHIVDLIWIFLFPLLYLVG
HHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STDNTAHGAHTAHVAHHFKTAEQQYSSGKEGIWLFMLTEILMFGAIFVGYALYHNEYPA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
MFAEGAKSLDWKMGFVNTLVLIFSSFTMAISISFIQKNQQKKAVLALATTVLCGAIFMVI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
KYFEYQHKFHLGLFPGKFLDVAKVGAEHANLGLYFGFYYVMTGLHGIHVLLGMGLITWCL
HHHHHHHHEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRTMRGDFHSQYWIVVEGVGLFWHIVDLIWIFLFPLLYLVG
HHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]