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The map label for this gene is atoS [H]

Identifier: 42521843

GI number: 42521843

Start: 203630

End: 205597

Strand: Direct

Name: atoS [H]

Synonym: Bd0216

Alternate gene names: 42521843

Gene position: 203630-205597 (Clockwise)

Preceding gene: 42521842

Following gene: 42521844

Centisome position: 5.38

GC content: 50.41

Gene sequence:

>1968_bases
GTGAAAACACTCCGGAAGAAACCCAAACGATCCCTGCGCACGATCCTGATCATCTGGTTCGTCCTGTTTTCAGTCGTGCC
ACTGGCGTTCGTTACCGGTTATTCCATGATCAAATACGAAAAAGCCATCGATCATGAGCTGTCCCAGCGCTTGAGCGGCA
ATGCCCGGGAAGTGGAGCTGATCCTGGCGGATCTTCTGACCAGCATTCAGCAAAAACGCGACCGCTATGTGCGCGATCCA
AGCCTTGTGTATCACATGGCGGAAGGGGACAGTGGCACCATCCGCAATATCTCCTCCCAATGGATCAAGGCTGACAATAT
TTCCAGTCTGACTTTCTTTAATCGCGAAGGCCGCATGCTGGCCTCGGTTTTCAAAGACGAAAAAGAGAACGTGCGCAGCT
TTGTTCCCGTGCAGGATGCGGTTTTTCTGTCTGCGAAATATATGGCGCAGGTTAAAGATCAGCGTGAAATCTCTTTGGCT
GAATTCGGTGACAAACAAAAAGTAAATCTGATCCTGATCTCCAAAATCACCGGGGCCGGTGGCCGCGTTGTGGGTTACAT
GGAACAGGTGATGGACCTGAACAAAGCCTTTGTGTCCAAGATCAAAAGCCGCCTGAAGCTGGAGCTGATCTTTTTCTCGG
ACAACGGGCAGGCGATCGTTGCCAGTCATCCGGATTTCTATCTCTATAAAAAAGACTTTTTCCGTCCTTACTTCCGCCCG
GGGGCGGAACCCTTCTTTGATCTGAATGTGCGCAGCACTCCCTATGGTTTTTTGATCTATCCGCTGAATTGGGGCATCAC
AAAGTTCTATGTGGCGCTAGGTGCTTCCAAGAGCGAAGCCAAGGCCGTTCTTAAGAACGTCAACTATGCCTTTATCAGCG
TCGTCGGTGCGGTTATTGTCCTGTTGATTCTGACAATTCTGGTGACCTCAAGCTGGGTTCTGAAACCACTTTACGAACTG
GTCGATGCCCTGCAGTCCTTTGAATCCCAGGAACAGGCTGTCACCATCCCGGTGAAAAATGACACCGAGATCGGTCTTTT
GACAGAGTCCTTCAATGAAATGAGCAAAAAAATCTGGGTGGCCCGTTCGGATCTTCGCAAGAAGATCACGGAACTTGAAG
CGGCCAACAAAGAGCTGAAAGACACTCAGACTAAGCTTGTTCACTCTGCCAAAATGGTCAGTCTGGGGCAGTTGGTGGCG
GGTGTGGCGCACGAGCTGAATAATCCGATTGGGTTTATCTACAGCAACATGACCCATCTGAAGGAATATTCTGAAAAACT
GATCGAGCTTGCCAAGGTTGCCGAGAAAGATCCGCCGAAACTTCCGGCCCTGAAAGAAGAGTACGAATTTGACTATATCG
TGAAGGATCTGCCGAAACTGGTGGCGTCTTGTCAGGATGGGGCTCGTCGTACGCGTGACATCGTTCTGGGTCTGCGCAAT
TTCTCTCGTCTGGAAGAGGCAAAGCTTCAGGAAATCGACGTTCATCAAAGCCTGGATACAACTTTGAATCTGTTGCAGGG
TGAAATCAAAAACCGCATCGAGATTCATCGTCAGTATGAACCTACTCCTTTGATCCACTGTTATGCCAGCCAGGTGAATC
AGGTGTTCATGAACATTCTGTCCAATGCGGTTCAGGCGATTGAAGGCAGCGGTCACATCTGGATTTCCACTTCGGCCTTG
AAGGACTACAAGGGCTCCAAGGACAAACGGGGCTGGGTGCAAGTCTCAATTCAAGACAGCGGTAAAGGCATGTCCGCCGA
TGTTCTGGAAAAGATCTTCGACCCGTTCTTCACCACCAAGGGGGTCGGTCAGGGGACGGGACTGGGTTTGAGCATCTCTT
ATGGTATTGTTCAGAACCACGGGGGCGAAATTCAGGCCCGCTCGGAAGTGGGCGTAGGCACAGAGTTTATCGTGATCATC
CCGGTTTATCCGCCGATTCAGGAAAAGAACCCTCAACCAACGTCCTAA

Upstream 100 bases:

>100_bases
TGGGCACTTATGGGAAGACCAAATTTTCCAAAGAAAAACACCCTCGTGTGATGCCAGACGGAATCATTCGTCTGATCTTC
ACTTTGGATGAATCCAAAAA

Downstream 100 bases:

>100_bases
ATCCAAAGCGCCTCCGAGTAGCAGACTATTTTGCAGTATGCACGCGGATCAGTACCCTCAAGCTGTCTCAACTTGAGACA
GGGCTAAACTTGAGAAATGG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MKTLRKKPKRSLRTILIIWFVLFSVVPLAFVTGYSMIKYEKAIDHELSQRLSGNAREVELILADLLTSIQQKRDRYVRDP
SLVYHMAEGDSGTIRNISSQWIKADNISSLTFFNREGRMLASVFKDEKENVRSFVPVQDAVFLSAKYMAQVKDQREISLA
EFGDKQKVNLILISKITGAGGRVVGYMEQVMDLNKAFVSKIKSRLKLELIFFSDNGQAIVASHPDFYLYKKDFFRPYFRP
GAEPFFDLNVRSTPYGFLIYPLNWGITKFYVALGASKSEAKAVLKNVNYAFISVVGAVIVLLILTILVTSSWVLKPLYEL
VDALQSFESQEQAVTIPVKNDTEIGLLTESFNEMSKKIWVARSDLRKKITELEAANKELKDTQTKLVHSAKMVSLGQLVA
GVAHELNNPIGFIYSNMTHLKEYSEKLIELAKVAEKDPPKLPALKEEYEFDYIVKDLPKLVASCQDGARRTRDIVLGLRN
FSRLEEAKLQEIDVHQSLDTTLNLLQGEIKNRIEIHRQYEPTPLIHCYASQVNQVFMNILSNAVQAIEGSGHIWISTSAL
KDYKGSKDKRGWVQVSIQDSGKGMSADVLEKIFDPFFTTKGVGQGTGLGLSISYGIVQNHGGEIQARSEVGVGTEFIVII
PVYPPIQEKNPQPTS

Sequences:

>Translated_655_residues
MKTLRKKPKRSLRTILIIWFVLFSVVPLAFVTGYSMIKYEKAIDHELSQRLSGNAREVELILADLLTSIQQKRDRYVRDP
SLVYHMAEGDSGTIRNISSQWIKADNISSLTFFNREGRMLASVFKDEKENVRSFVPVQDAVFLSAKYMAQVKDQREISLA
EFGDKQKVNLILISKITGAGGRVVGYMEQVMDLNKAFVSKIKSRLKLELIFFSDNGQAIVASHPDFYLYKKDFFRPYFRP
GAEPFFDLNVRSTPYGFLIYPLNWGITKFYVALGASKSEAKAVLKNVNYAFISVVGAVIVLLILTILVTSSWVLKPLYEL
VDALQSFESQEQAVTIPVKNDTEIGLLTESFNEMSKKIWVARSDLRKKITELEAANKELKDTQTKLVHSAKMVSLGQLVA
GVAHELNNPIGFIYSNMTHLKEYSEKLIELAKVAEKDPPKLPALKEEYEFDYIVKDLPKLVASCQDGARRTRDIVLGLRN
FSRLEEAKLQEIDVHQSLDTTLNLLQGEIKNRIEIHRQYEPTPLIHCYASQVNQVFMNILSNAVQAIEGSGHIWISTSAL
KDYKGSKDKRGWVQVSIQDSGKGMSADVLEKIFDPFFTTKGVGQGTGLGLSISYGIVQNHGGEIQARSEVGVGTEFIVII
PVYPPIQEKNPQPTS
>Mature_655_residues
MKTLRKKPKRSLRTILIIWFVLFSVVPLAFVTGYSMIKYEKAIDHELSQRLSGNAREVELILADLLTSIQQKRDRYVRDP
SLVYHMAEGDSGTIRNISSQWIKADNISSLTFFNREGRMLASVFKDEKENVRSFVPVQDAVFLSAKYMAQVKDQREISLA
EFGDKQKVNLILISKITGAGGRVVGYMEQVMDLNKAFVSKIKSRLKLELIFFSDNGQAIVASHPDFYLYKKDFFRPYFRP
GAEPFFDLNVRSTPYGFLIYPLNWGITKFYVALGASKSEAKAVLKNVNYAFISVVGAVIVLLILTILVTSSWVLKPLYEL
VDALQSFESQEQAVTIPVKNDTEIGLLTESFNEMSKKIWVARSDLRKKITELEAANKELKDTQTKLVHSAKMVSLGQLVA
GVAHELNNPIGFIYSNMTHLKEYSEKLIELAKVAEKDPPKLPALKEEYEFDYIVKDLPKLVASCQDGARRTRDIVLGLRN
FSRLEEAKLQEIDVHQSLDTTLNLLQGEIKNRIEIHRQYEPTPLIHCYASQVNQVFMNILSNAVQAIEGSGHIWISTSAL
KDYKGSKDKRGWVQVSIQDSGKGMSADVLEKIFDPFFTTKGVGQGTGLGLSISYGIVQNHGGEIQARSEVGVGTEFIVII
PVYPPIQEKNPQPTS

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=270, Percent_Identity=30.7407407407407, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1790436, Length=273, Percent_Identity=31.5018315018315, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1790300, Length=277, Percent_Identity=27.0758122743682, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI145693157, Length=205, Percent_Identity=29.2682926829268, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=156, Percent_Identity=32.0512820512821, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788393, Length=346, Percent_Identity=21.6763005780347, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73770; Mature: 73770

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLRKKPKRSLRTILIIWFVLFSVVPLAFVTGYSMIKYEKAIDHELSQRLSGNAREVEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ILADLLTSIQQKRDRYVRDPSLVYHMAEGDSGTIRNISSQWIKADNISSLTFFNREGRML
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHCCHHHHEECCCCCEEEEECCCCHHH
ASVFKDEKENVRSFVPVQDAVFLSAKYMAQVKDQREISLAEFGDKQKVNLILISKITGAG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEEEEEECCCC
GRVVGYMEQVMDLNKAFVSKIKSRLKLELIFFSDNGQAIVASHPDFYLYKKDFFRPYFRP
CHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCEEEECCCCEEEEEHHHCCHHHCC
GAEPFFDLNVRSTPYGFLIYPLNWGITKFYVALGASKSEAKAVLKNVNYAFISVVGAVIV
CCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHH
LLILTILVTSSWVLKPLYELVDALQSFESQEQAVTIPVKNDTEIGLLTESFNEMSKKIWV
HHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHH
ARSDLRKKITELEAANKELKDTQTKLVHSAKMVSLGQLVAGVAHELNNPIGFIYSNMTHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
KEYSEKLIELAKVAEKDPPKLPALKEEYEFDYIVKDLPKLVASCQDGARRTRDIVLGLRN
HHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSRLEEAKLQEIDVHQSLDTTLNLLQGEIKNRIEIHRQYEPTPLIHCYASQVNQVFMNIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
SNAVQAIEGSGHIWISTSALKDYKGSKDKRGWVQVSIQDSGKGMSADVLEKIFDPFFTTK
HHHHHHHCCCCCEEEEECHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCC
GVGQGTGLGLSISYGIVQNHGGEIQARSEVGVGTEFIVIIPVYPPIQEKNPQPTS
CCCCCCCCEEEEEECCEECCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKTLRKKPKRSLRTILIIWFVLFSVVPLAFVTGYSMIKYEKAIDHELSQRLSGNAREVEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ILADLLTSIQQKRDRYVRDPSLVYHMAEGDSGTIRNISSQWIKADNISSLTFFNREGRML
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHCCHHHHEECCCCCEEEEECCCCHHH
ASVFKDEKENVRSFVPVQDAVFLSAKYMAQVKDQREISLAEFGDKQKVNLILISKITGAG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEEEEEEECCCC
GRVVGYMEQVMDLNKAFVSKIKSRLKLELIFFSDNGQAIVASHPDFYLYKKDFFRPYFRP
CHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCEEEECCCCEEEEEHHHCCHHHCC
GAEPFFDLNVRSTPYGFLIYPLNWGITKFYVALGASKSEAKAVLKNVNYAFISVVGAVIV
CCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHH
LLILTILVTSSWVLKPLYELVDALQSFESQEQAVTIPVKNDTEIGLLTESFNEMSKKIWV
HHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHH
ARSDLRKKITELEAANKELKDTQTKLVHSAKMVSLGQLVAGVAHELNNPIGFIYSNMTHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
KEYSEKLIELAKVAEKDPPKLPALKEEYEFDYIVKDLPKLVASCQDGARRTRDIVLGLRN
HHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSRLEEAKLQEIDVHQSLDTTLNLLQGEIKNRIEIHRQYEPTPLIHCYASQVNQVFMNIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
SNAVQAIEGSGHIWISTSALKDYKGSKDKRGWVQVSIQDSGKGMSADVLEKIFDPFFTTK
HHHHHHHCCCCCEEEEECHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCC
GVGQGTGLGLSISYGIVQNHGGEIQARSEVGVGTEFIVIIPVYPPIQEKNPQPTS
CCCCCCCCEEEEEECCEECCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]