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The map label for this gene is glpD [H]

Identifier: 42521837

GI number: 42521837

Start: 193302

End: 194936

Strand: Direct

Name: glpD [H]

Synonym: Bd0208

Alternate gene names: 42521837

Gene position: 193302-194936 (Clockwise)

Preceding gene: 42521836

Following gene: 42521839

Centisome position: 5.11

GC content: 51.8

Gene sequence:

>1635_bases
ATGAAGAATTTCTCCTTCGCAAACAGAATTCAAAATATCAACAAGATGAAATCCCAGGATTTTGATCTCGTGATAATCGG
GGGAGGAATCAACGGGGCGGGTGTGGCGCGGGATGCTTCGGCACGCGGTATGCGAGTGGCTTTGATCGAAGCCCGTGACT
TTGCCTCTGGCACGTCGTCGAAATCCTCAAAGCTTATTCACGGTGGCATTCGTTATCTGGAAAACATGGAATTCAAACTT
GTTTTCGAGGCCCTGAATGAACGAGGCCGCCTGTTTGAAATGGCCCCGCATCTGGTGCATCCACTGCGTTTTATGATTCC
GCTTTATCAGGAAAGCCGCGTGGGCATGGGGAAGATGGGTCTTGGCATGTGGCTTTATGATGCGCTGTCATTGTTCCAGG
CTCCAGAGATGCATGAGCGACTGGATGCCCAAGCCTCGATGGAACGCATGCCGGCGATTCGTCCCAATAATTTGCTGGGT
TCCTACATTTATTCCGACGCCTACATGGACGATGATCGTCTGGTTCATGAAACCATGAGATCGGCCAATGAAAACGGTGC
GCTTTGTGTGAACTATGTGAAAGCCACCGGGGTGACTTTCGGTCCGGATGGAAAAATTCAGGCCGTGAAGTGTGAAGATC
AGCACTCTAAAGAAAAATTCACGATCAAAGCCCGTCACGTGATCAGCAGTGTGGGTCCGTGGACCGATGAATTGGGTGAA
AACATTTTTAAGGACTGGAAGAAAATTCTTCGTCCGACCAAAGGCATTCACCTGACATTGCCCAAGCACCGTCTGCCATT
GACCAGCGCGGTGGTGATGGGCGCGGAAAAAAGTGATCGCATCGTGTTCGGGATTCCCCGTCATGAGATGATCATAATTG
GAACCACTGACACCGACTTTAAGGAATCTCCGGAAAACGTGACAACCACGCCGGAGGATGTGAAGTATCTGCTTTCTATC
ACAGATCACTATTTCCCGGGCGCCAACCTGACCGCTCACGATATCATCGCCAGCTATGCGGGTGTTCGCCCCTTGGTGGC
GGATGGCTCCAGCAGCGAAGGCAAAACCAGCCGCGAGCACACGATTTTGTCCGACGACCGCGGAATCACTTTTGTTGCCG
GCGGAAAGTACACCACCTATCGCCTGATGTGCGAACAAACCGTGAAGGCAGCGTTGAAATTCTTTACGTTTGAAGAGCGT
GTGACCTGGGGCAAATCCGATACCGTCAAGCCATTGAATCCGTACACCAGCATCGACGCCTTCCAACAGGCCAAGGTTCA
GGCGGATCTATGGGCTCGTGAAACGGGACACTCTGTGGAGGACATGCGTTTGCTGGCTGAGCGTTATGGCATGGAAGGCG
AAGAGATCCTGAACAAGTATTCCGCTGACATGACCTACTGGCAGCTGGAGGCGGCTCAGGCCATTGATTCAACGATGTGT
CTGCATATGCGTGACTTCTTTGCGCGCCGGGTTCCTTTATTCCTGGCCGATCGCAATCACGGTGTGAAACACATGGAGGA
AATCGGCAAGGTCTTCCAGGAAAAGCTGGGATGGAACGAAGCCCGTCTGAAGGAAGAAATGCACATGCTGACCGAGTACA
TGGCCCGTGAAGTGGAATGGAAGAAACACTTCTAA

Upstream 100 bases:

>100_bases
CTTCCCCAATGACAACGGAGTGCCGAACTCCGTAAAAGCTTTCAAGGCCGAAAGCTGGCAGCCGGGGACTCTTTCAGTCA
AGACGACAAAAGGATAAGCC

Downstream 100 bases:

>100_bases
GGCAGGAAGTATTCTGAGACGGCCGGCAACCCGTTTTGCATGGCCATAAAGACCAGACGTTTTGGTTTTGGTCCGGAAGC
GGCTTTGATCAGAATGCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MKNFSFANRIQNINKMKSQDFDLVIIGGGINGAGVARDASARGMRVALIEARDFASGTSSKSSKLIHGGIRYLENMEFKL
VFEALNERGRLFEMAPHLVHPLRFMIPLYQESRVGMGKMGLGMWLYDALSLFQAPEMHERLDAQASMERMPAIRPNNLLG
SYIYSDAYMDDDRLVHETMRSANENGALCVNYVKATGVTFGPDGKIQAVKCEDQHSKEKFTIKARHVISSVGPWTDELGE
NIFKDWKKILRPTKGIHLTLPKHRLPLTSAVVMGAEKSDRIVFGIPRHEMIIIGTTDTDFKESPENVTTTPEDVKYLLSI
TDHYFPGANLTAHDIIASYAGVRPLVADGSSSEGKTSREHTILSDDRGITFVAGGKYTTYRLMCEQTVKAALKFFTFEER
VTWGKSDTVKPLNPYTSIDAFQQAKVQADLWARETGHSVEDMRLLAERYGMEGEEILNKYSADMTYWQLEAAQAIDSTMC
LHMRDFFARRVPLFLADRNHGVKHMEEIGKVFQEKLGWNEARLKEEMHMLTEYMAREVEWKKHF

Sequences:

>Translated_544_residues
MKNFSFANRIQNINKMKSQDFDLVIIGGGINGAGVARDASARGMRVALIEARDFASGTSSKSSKLIHGGIRYLENMEFKL
VFEALNERGRLFEMAPHLVHPLRFMIPLYQESRVGMGKMGLGMWLYDALSLFQAPEMHERLDAQASMERMPAIRPNNLLG
SYIYSDAYMDDDRLVHETMRSANENGALCVNYVKATGVTFGPDGKIQAVKCEDQHSKEKFTIKARHVISSVGPWTDELGE
NIFKDWKKILRPTKGIHLTLPKHRLPLTSAVVMGAEKSDRIVFGIPRHEMIIIGTTDTDFKESPENVTTTPEDVKYLLSI
TDHYFPGANLTAHDIIASYAGVRPLVADGSSSEGKTSREHTILSDDRGITFVAGGKYTTYRLMCEQTVKAALKFFTFEER
VTWGKSDTVKPLNPYTSIDAFQQAKVQADLWARETGHSVEDMRLLAERYGMEGEEILNKYSADMTYWQLEAAQAIDSTMC
LHMRDFFARRVPLFLADRNHGVKHMEEIGKVFQEKLGWNEARLKEEMHMLTEYMAREVEWKKHF
>Mature_544_residues
MKNFSFANRIQNINKMKSQDFDLVIIGGGINGAGVARDASARGMRVALIEARDFASGTSSKSSKLIHGGIRYLENMEFKL
VFEALNERGRLFEMAPHLVHPLRFMIPLYQESRVGMGKMGLGMWLYDALSLFQAPEMHERLDAQASMERMPAIRPNNLLG
SYIYSDAYMDDDRLVHETMRSANENGALCVNYVKATGVTFGPDGKIQAVKCEDQHSKEKFTIKARHVISSVGPWTDELGE
NIFKDWKKILRPTKGIHLTLPKHRLPLTSAVVMGAEKSDRIVFGIPRHEMIIIGTTDTDFKESPENVTTTPEDVKYLLSI
TDHYFPGANLTAHDIIASYAGVRPLVADGSSSEGKTSREHTILSDDRGITFVAGGKYTTYRLMCEQTVKAALKFFTFEER
VTWGKSDTVKPLNPYTSIDAFQQAKVQADLWARETGHSVEDMRLLAERYGMEGEEILNKYSADMTYWQLEAAQAIDSTMC
LHMRDFFARRVPLFLADRNHGVKHMEEIGKVFQEKLGWNEARLKEEMHMLTEYMAREVEWKKHF

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=559, Percent_Identity=28.9803220035778, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI285002231, Length=559, Percent_Identity=28.9803220035778, Blast_Score=253, Evalue=3e-67,
Organism=Escherichia coli, GI2367226, Length=362, Percent_Identity=33.1491712707182, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1788574, Length=365, Percent_Identity=26.5753424657534, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17509253, Length=549, Percent_Identity=30.0546448087432, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI115534726, Length=564, Percent_Identity=29.0780141843972, Blast_Score=196, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6322036, Length=535, Percent_Identity=31.588785046729, Blast_Score=222, Evalue=1e-58,
Organism=Drosophila melanogaster, GI161077125, Length=553, Percent_Identity=29.1139240506329, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24653942, Length=553, Percent_Identity=29.1139240506329, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24653944, Length=553, Percent_Identity=29.1139240506329, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI20130025, Length=553, Percent_Identity=29.1139240506329, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24586295, Length=546, Percent_Identity=24.5421245421245, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI19921278, Length=557, Percent_Identity=25.4937163375224, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI45550977, Length=411, Percent_Identity=21.654501216545, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 61719; Mature: 61719

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFSFANRIQNINKMKSQDFDLVIIGGGINGAGVARDASARGMRVALIEARDFASGTSS
CCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
KSSKLIHGGIRYLENMEFKLVFEALNERGRLFEMAPHLVHPLRFMIPLYQESRVGMGKMG
CCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LGMWLYDALSLFQAPEMHERLDAQASMERMPAIRPNNLLGSYIYSDAYMDDDRLVHETMR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
SANENGALCVNYVKATGVTFGPDGKIQAVKCEDQHSKEKFTIKARHVISSVGPWTDELGE
CCCCCCCEEEEEEECCCEEECCCCCEEEEECCCCCCCCCEEEHHHHHHHHCCCCHHHHHH
NIFKDWKKILRPTKGIHLTLPKHRLPLTSAVVMGAEKSDRIVFGIPRHEMIIIGTTDTDF
HHHHHHHHHHCCCCCEEEECCCCCCCHHHHHEECCCCCCCEEEECCCCCEEEEECCCCCC
KESPENVTTTPEDVKYLLSITDHYFPGANLTAHDIIASYAGVRPLVADGSSSEGKTSREH
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCC
TILSDDRGITFVAGGKYTTYRLMCEQTVKAALKFFTFEERVTWGKSDTVKPLNPYTSIDA
EEEECCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
FQQAKVQADLWARETGHSVEDMRLLAERYGMEGEEILNKYSADMTYWQLEAAQAIDSTMC
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHH
LHMRDFFARRVPLFLADRNHGVKHMEEIGKVFQEKLGWNEARLKEEMHMLTEYMAREVEW
HHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KKHF
HCCC
>Mature Secondary Structure
MKNFSFANRIQNINKMKSQDFDLVIIGGGINGAGVARDASARGMRVALIEARDFASGTSS
CCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
KSSKLIHGGIRYLENMEFKLVFEALNERGRLFEMAPHLVHPLRFMIPLYQESRVGMGKMG
CCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LGMWLYDALSLFQAPEMHERLDAQASMERMPAIRPNNLLGSYIYSDAYMDDDRLVHETMR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
SANENGALCVNYVKATGVTFGPDGKIQAVKCEDQHSKEKFTIKARHVISSVGPWTDELGE
CCCCCCCEEEEEEECCCEEECCCCCEEEEECCCCCCCCCEEEHHHHHHHHCCCCHHHHHH
NIFKDWKKILRPTKGIHLTLPKHRLPLTSAVVMGAEKSDRIVFGIPRHEMIIIGTTDTDF
HHHHHHHHHHCCCCCEEEECCCCCCCHHHHHEECCCCCCCEEEECCCCCEEEEECCCCCC
KESPENVTTTPEDVKYLLSITDHYFPGANLTAHDIIASYAGVRPLVADGSSSEGKTSREH
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCC
TILSDDRGITFVAGGKYTTYRLMCEQTVKAALKFFTFEERVTWGKSDTVKPLNPYTSIDA
EEEECCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
FQQAKVQADLWARETGHSVEDMRLLAERYGMEGEEILNKYSADMTYWQLEAAQAIDSTMC
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHH
LHMRDFFARRVPLFLADRNHGVKHMEEIGKVFQEKLGWNEARLKEEMHMLTEYMAREVEW
HHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
KKHF
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA