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The map label for this gene is yqiD [C]

Identifier: 42521829

GI number: 42521829

Start: 185085

End: 185954

Strand: Direct

Name: yqiD [C]

Synonym: Bd0199

Alternate gene names: 42521829

Gene position: 185085-185954 (Clockwise)

Preceding gene: 42521828

Following gene: 42521830

Centisome position: 4.89

GC content: 51.95

Gene sequence:

>870_bases
TTGGATCTCGCAATTCAGATTGATCAGGAAATCGCCGCGCGCACCCAGGCTGTGAACCAGTTTGTGGAAAAATATCTGTC
TGACATGGAGCTACCAGCAGGCAGCGCCATTTCTGAGTTGCGAAAGTCCATGCTTTATTCCGCCACCAATGGCGGGAAAC
GTTTCCGTCCGGTTCTGTCCTTGCTGGTCGGTGAGTTGTTCGGTGCTGGTAAAGAGCGCATCTTGCCTTTCGCCGCTGCC
GTGGAAATGATTCATACGTACTCTTTGATTCATGATGATCTGCCATGCATGGATAACGATGACATGCGCCGCGGGAAGCC
CACCAATCACAAAGTGTTCGGTGAAGACTTTGCGTTGCTGGCCGGGGACGCTCTTTTGACTGAAGCTTTCATGCTGATTG
CGGAAAACTATGGGGATAACAGCTTCCTGGTGGGTCACCTGACAAGGCTGTTATCTTCGGCGGCAGGAATTCGAGGCATG
GTCGGTGGTCAGGCGATTGACCTGCGTGCTGGTGACAAACAAATGTCACTGGAAGAACTGACCCATCTGCATCGTCTTAA
AACCGGTGCGTTGATTCGTGTGGCGGTTGAGGGTGCGGCTGTGATTGCCGGGGCAAAGCCGACTGAAATTGAAAGTCTTA
AAAAATTCGGCGAAGGCCTGGGCCTTGCTTTCCAAGTGGCCGACGATGTTCTGGATCACGGCGAAAAAGGTCAGGATCTT
CGCAGCTTCACCGGTATCCTGGGTCTTGAGGGCACAAAGACCTATTTGAAGGATGTCAGTGCTTCGACTTTGGCGGAACT
GCACAAGGTGTCTGCCGATGCTCCGCTTTTGGAGTATCTGATCAGCTTTAATCAAAACCGTCAGGTGTAA

Upstream 100 bases:

>100_bases
GCGTCTGAATGAAGCTGAATCCAAAGTGAAACTGTTGATGTCTGTGGGAGCTGACGGCCAGCCGGTGACCACTGATTTCA
CTTCAGAGGAGAACTAAGCC

Downstream 100 bases:

>100_bases
TATGGGCGAAAAACTGCGTTTGGATCTTTATCTTGTCGAAAAGGGTCTGGCGCAGTCGCGCACTCATGCTCAGGAGCTGA
TCGAAGCCGGTCAGGTTTTT

Product: geranyltranstransferase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDLAIQIDQEIAARTQAVNQFVEKYLSDMELPAGSAISELRKSMLYSATNGGKRFRPVLSLLVGELFGAGKERILPFAAA
VEMIHTYSLIHDDLPCMDNDDMRRGKPTNHKVFGEDFALLAGDALLTEAFMLIAENYGDNSFLVGHLTRLLSSAAGIRGM
VGGQAIDLRAGDKQMSLEELTHLHRLKTGALIRVAVEGAAVIAGAKPTEIESLKKFGEGLGLAFQVADDVLDHGEKGQDL
RSFTGILGLEGTKTYLKDVSASTLAELHKVSADAPLLEYLISFNQNRQV

Sequences:

>Translated_289_residues
MDLAIQIDQEIAARTQAVNQFVEKYLSDMELPAGSAISELRKSMLYSATNGGKRFRPVLSLLVGELFGAGKERILPFAAA
VEMIHTYSLIHDDLPCMDNDDMRRGKPTNHKVFGEDFALLAGDALLTEAFMLIAENYGDNSFLVGHLTRLLSSAAGIRGM
VGGQAIDLRAGDKQMSLEELTHLHRLKTGALIRVAVEGAAVIAGAKPTEIESLKKFGEGLGLAFQVADDVLDHGEKGQDL
RSFTGILGLEGTKTYLKDVSASTLAELHKVSADAPLLEYLISFNQNRQV
>Mature_289_residues
MDLAIQIDQEIAARTQAVNQFVEKYLSDMELPAGSAISELRKSMLYSATNGGKRFRPVLSLLVGELFGAGKERILPFAAA
VEMIHTYSLIHDDLPCMDNDDMRRGKPTNHKVFGEDFALLAGDALLTEAFMLIAENYGDNSFLVGHLTRLLSSAAGIRGM
VGGQAIDLRAGDKQMSLEELTHLHRLKTGALIRVAVEGAAVIAGAKPTEIESLKKFGEGLGLAFQVADDVLDHGEKGQDL
RSFTGILGLEGTKTYLKDVSASTLAELHKVSADAPLLEYLISFNQNRQV

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=209, Percent_Identity=32.5358851674641, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1786623, Length=301, Percent_Identity=39.202657807309, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1789578, Length=201, Percent_Identity=31.8407960199005, Blast_Score=104, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17505681, Length=229, Percent_Identity=26.6375545851528, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24651612, Length=214, Percent_Identity=31.3084112149533, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 31316; Mature: 31316

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAIQIDQEIAARTQAVNQFVEKYLSDMELPAGSAISELRKSMLYSATNGGKRFRPVLS
CCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LLVGELFGAGKERILPFAAAVEMIHTYSLIHDDLPCMDNDDMRRGKPTNHKVFGEDFALL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AGDALLTEAFMLIAENYGDNSFLVGHLTRLLSSAAGIRGMVGGQAIDLRAGDKQMSLEEL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHH
THLHRLKTGALIRVAVEGAAVIAGAKPTEIESLKKFGEGLGLAFQVADDVLDHGEKGQDL
HHHHHHCCCCEEEEEECCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHH
RSFTGILGLEGTKTYLKDVSASTLAELHKVSADAPLLEYLISFNQNRQV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDLAIQIDQEIAARTQAVNQFVEKYLSDMELPAGSAISELRKSMLYSATNGGKRFRPVLS
CCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LLVGELFGAGKERILPFAAAVEMIHTYSLIHDDLPCMDNDDMRRGKPTNHKVFGEDFALL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AGDALLTEAFMLIAENYGDNSFLVGHLTRLLSSAAGIRGMVGGQAIDLRAGDKQMSLEEL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHH
THLHRLKTGALIRVAVEGAAVIAGAKPTEIESLKKFGEGLGLAFQVADDVLDHGEKGQDL
HHHHHHCCCCEEEEEECCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHH
RSFTGILGLEGTKTYLKDVSASTLAELHKVSADAPLLEYLISFNQNRQV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486607; 7918490 [H]