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The map label for this gene is csdB [C]

Identifier: 42521821

GI number: 42521821

Start: 175494

End: 176723

Strand: Direct

Name: csdB [C]

Synonym: Bd0189

Alternate gene names: 42521821

Gene position: 175494-176723 (Clockwise)

Preceding gene: 42521820

Following gene: 42521822

Centisome position: 4.64

GC content: 50.89

Gene sequence:

>1230_bases
ATGAGTAATCTAGACGACATATTTGCCTCTGTAAGATCCCAGTTTCCGGCTTTGACTCAGAAAGTTCATGGCAAGAACCT
GGTTTATCTGGACAGTGGTGCGACAACTTTGAAGCCGCAGTCGGTGGTCGACCGTATTGCGCATTTTTATTCTTATGAAA
CTTCCAATGTTCATCGTGGCGCACACTATCTGGGTGACGTGGCGACCGGACATTTCGAAGCGGCCCGCCAGAAGGTGGCC
GAATTCCTGGGTGCCCGTCAGTCCGAGGAAATCATCTTTGTTCGTGGCACCACCGAGGGCGTGAACCTGGTGGCAAATTC
CTGGGGCCTTTCCAACTTGAAGGCCGGGGATGAGATCCTGATCACCGTGATGGAGCATCACGGAAACATCGTGCCGTGGC
AGATGGTCGCAGAAAAAGTCGGCGCCAAAGTCGTGGCCGCGGATATTCTGGACAATGGCGAGCTGGATCTTGAAGACTTC
AAAAAGAAATTGAACTCTCGCACGAAGATGGTGGCTTTCACCGCTTCTTCGAATGTTCTGGGCACGAACACAGACATGAA
GCTTTTGACCAAGCTTGCTCATGAAGTGGGTGCGAAGGTTCTGGTGGATGGGGCGCAGATCGTGTCTCAGTTGCCGGTGG
ATGTTTCTGATATTGATTGCGACTTCTTTGTGTTTTCTGCACACAAGCTTTTCGGCCCGTTTGGGTTTGGGGCTGTGTAC
GGAAAAAAAGAGATTCTGGATCAGATGCCCCCTTATCAGGGTGGCGGCAGTATGATTTCCAAGGTGACGATCGAAAAAAC
CACGTTCAATGATGTGCCGACGCGCTTTGAGGCCGGAACTCCGCACGTGGAAGGCGCCGTGGGATTGCATGCGGCACTGA
CGTTCGTTGAGAACATCGGTCTGGATAAGATTCATAAATATGAGATGGATCTTTTGAACTACGCAACTGGCAGGCTTCTG
GAGATCCCGGATGTAAAAATCTACGGAACCTCTCAGAATAAAGGGGCGATTTTGTCCTTTAATCTGAAAGGGGCTCACCA
CTCTGACATTGGTCAGATTCTGGACCAAGAAGGTGTGGCAGTCAGAGCAGGACACCATTGTACGCAGCCGCTGATGGCGC
GTCTGGGAGTTCCCGGCACCGTCAGAGCATCCCTTTCAGTGTATAATAATCGTGAAGATATTGATTCTATGGTTAAAGCC
GTGGTGAAAGCCCGGGAGATGTTGTTATGA

Upstream 100 bases:

>100_bases
CTGAAGTGATTTACAAAATTTCCGACGAGAACATCCAGAAATGGTTGTCTCGCCATCTGGACGAGGCGTTCAGCAGCCTT
GCCCTGAATCGGTAAGTGAT

Downstream 100 bases:

>100_bases
GCACCCAAGATGTACTGATTCGTATTCAGGCAACTCCGAACCCCAATGCGTGGAAATTCGTTTTGGATCGCGCCGTCTTG
AATGACGGCAAGGCGACCTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSNLDDIFASVRSQFPALTQKVHGKNLVYLDSGATTLKPQSVVDRIAHFYSYETSNVHRGAHYLGDVATGHFEAARQKVA
EFLGARQSEEIIFVRGTTEGVNLVANSWGLSNLKAGDEILITVMEHHGNIVPWQMVAEKVGAKVVAADILDNGELDLEDF
KKKLNSRTKMVAFTASSNVLGTNTDMKLLTKLAHEVGAKVLVDGAQIVSQLPVDVSDIDCDFFVFSAHKLFGPFGFGAVY
GKKEILDQMPPYQGGGSMISKVTIEKTTFNDVPTRFEAGTPHVEGAVGLHAALTFVENIGLDKIHKYEMDLLNYATGRLL
EIPDVKIYGTSQNKGAILSFNLKGAHHSDIGQILDQEGVAVRAGHHCTQPLMARLGVPGTVRASLSVYNNREDIDSMVKA
VVKAREMLL

Sequences:

>Translated_409_residues
MSNLDDIFASVRSQFPALTQKVHGKNLVYLDSGATTLKPQSVVDRIAHFYSYETSNVHRGAHYLGDVATGHFEAARQKVA
EFLGARQSEEIIFVRGTTEGVNLVANSWGLSNLKAGDEILITVMEHHGNIVPWQMVAEKVGAKVVAADILDNGELDLEDF
KKKLNSRTKMVAFTASSNVLGTNTDMKLLTKLAHEVGAKVLVDGAQIVSQLPVDVSDIDCDFFVFSAHKLFGPFGFGAVY
GKKEILDQMPPYQGGGSMISKVTIEKTTFNDVPTRFEAGTPHVEGAVGLHAALTFVENIGLDKIHKYEMDLLNYATGRLL
EIPDVKIYGTSQNKGAILSFNLKGAHHSDIGQILDQEGVAVRAGHHCTQPLMARLGVPGTVRASLSVYNNREDIDSMVKA
VVKAREMLL
>Mature_408_residues
SNLDDIFASVRSQFPALTQKVHGKNLVYLDSGATTLKPQSVVDRIAHFYSYETSNVHRGAHYLGDVATGHFEAARQKVAE
FLGARQSEEIIFVRGTTEGVNLVANSWGLSNLKAGDEILITVMEHHGNIVPWQMVAEKVGAKVVAADILDNGELDLEDFK
KKLNSRTKMVAFTASSNVLGTNTDMKLLTKLAHEVGAKVLVDGAQIVSQLPVDVSDIDCDFFVFSAHKLFGPFGFGAVYG
KKEILDQMPPYQGGGSMISKVTIEKTTFNDVPTRFEAGTPHVEGAVGLHAALTFVENIGLDKIHKYEMDLLNYATGRLLE
IPDVKIYGTSQNKGAILSFNLKGAHHSDIGQILDQEGVAVRAGHHCTQPLMARLGVPGTVRASLSVYNNREDIDSMVKAV
VKAREMLL

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=403, Percent_Identity=24.0694789081886, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1787970, Length=399, Percent_Identity=48.8721804511278, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1789175, Length=401, Percent_Identity=41.1471321695761, Blast_Score=334, Evalue=8e-93,
Organism=Escherichia coli, GI48994898, Length=395, Percent_Identity=25.3164556962025, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193211090, Length=374, Percent_Identity=25.4010695187166, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25143064, Length=229, Percent_Identity=27.9475982532751, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319831, Length=233, Percent_Identity=28.3261802575107, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI20129463, Length=423, Percent_Identity=25.531914893617, Blast_Score=108, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44534; Mature: 44403

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLDDIFASVRSQFPALTQKVHGKNLVYLDSGATTLKPQSVVDRIAHFYSYETSNVHRG
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
AHYLGDVATGHFEAARQKVAEFLGARQSEEIIFVRGTTEGVNLVANSWGLSNLKAGDEIL
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCEE
ITVMEHHGNIVPWQMVAEKVGAKVVAADILDNGELDLEDFKKKLNSRTKMVAFTASSNVL
EEEEHHCCCCCHHHHHHHHHCCEEEEEEHHCCCCCCHHHHHHHHCCCCEEEEEEECCCEE
GTNTDMKLLTKLAHEVGAKVLVDGAQIVSQLPVDVSDIDCDFFVFSAHKLFGPFGFGAVY
CCCCHHHHHHHHHHHCCCEEEECHHHHHHHCCCCCCCCCCCEEEEEHHHHHCCCCCHHHH
GKKEILDQMPPYQGGGSMISKVTIEKTTFNDVPTRFEAGTPHVEGAVGLHAALTFVENIG
CHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LDKIHKYEMDLLNYATGRLLEIPDVKIYGTSQNKGAILSFNLKGAHHSDIGQILDQEGVA
HHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCCE
VRAGHHCTQPLMARLGVPGTVRASLSVYNNREDIDSMVKAVVKAREMLL
EECCCCCCHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNLDDIFASVRSQFPALTQKVHGKNLVYLDSGATTLKPQSVVDRIAHFYSYETSNVHRG
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
AHYLGDVATGHFEAARQKVAEFLGARQSEEIIFVRGTTEGVNLVANSWGLSNLKAGDEIL
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCEE
ITVMEHHGNIVPWQMVAEKVGAKVVAADILDNGELDLEDFKKKLNSRTKMVAFTASSNVL
EEEEHHCCCCCHHHHHHHHHCCEEEEEEHHCCCCCCHHHHHHHHCCCCEEEEEEECCCEE
GTNTDMKLLTKLAHEVGAKVLVDGAQIVSQLPVDVSDIDCDFFVFSAHKLFGPFGFGAVY
CCCCHHHHHHHHHHHCCCEEEECHHHHHHHCCCCCCCCCCCEEEEEHHHHHCCCCCHHHH
GKKEILDQMPPYQGGGSMISKVTIEKTTFNDVPTRFEAGTPHVEGAVGLHAALTFVENIG
CHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
LDKIHKYEMDLLNYATGRLLEIPDVKIYGTSQNKGAILSFNLKGAHHSDIGQILDQEGVA
HHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCCE
VRAGHHCTQPLMARLGVPGTVRASLSVYNNREDIDSMVKAVVKAREMLL
EECCCCCCHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA