Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 42521695

GI number: 42521695

Start: 41978

End: 42667

Strand: Direct

Name: dapB

Synonym: Bd0047

Alternate gene names: 42521695

Gene position: 41978-42667 (Clockwise)

Preceding gene: 42521694

Following gene: 42521696

Centisome position: 1.11

GC content: 50.58

Gene sequence:

>690_bases
GTGAAGAAAATCAAAATCGGCCTGATGGGTTCTGCCGGCCGTATGGGTCAAGAGATCGCCGGGGTGATTGAAGCCAACCC
CCGCTGCGAACTGGTGTATGCTCCCCTGCGCGGTGAAAAGTGGGACTCCAAGAAAGCGCAAGCTGTGGATGTGTGGATTG
ACTTCACTTCACCGGAAGCCCTGAAAGATATTTTGAAAAAAGCCAGCGAAACCAAAACACCGGTGGTGTGCGGAACGACG
GGCTTTTCCAAAAAAGAAAAAGAGCTGCTGAAAACCTACAGCAAAAAAATTCCGGTTCTGTGGTCTTCGAACATGAGCCT
GGGTGTGGCGGTGCTGAACGAAGCGCTGAAAGCCTTTTCCGCGATTTCGCATTTTGATTTCCAGATTGAGGAAATCCACC
ACAATCGTAAAAAAGACCGACCTTCCGGAACGGCGATCACCCTGCAGGAAAATCTGGAAAAAGCGGTGGATAAGAAACTT
CCTGAAGCTTTGGCCATTCGCGGGGGCGGCGTGTTTGGAGTGCACAAGATCTTTGCCATGAGTGATGAAGAGGTTTTGAC
CTTTGAACACACGGCCTTGAACCGCACCGTCTTTGCCAAAGGTTCTGTGCAGGCGGCCGAGTGGCTGGTGAAACAAAAGC
CGGGTCTTTATCAGATCCGCGATGTTCTGTTCGGAAAAAGCAAAAAATGA

Upstream 100 bases:

>100_bases
TGGGCATTCTGGAGTCCGCAGAACTGCGTCTGCCATTGGTGGAGCTGGGTGCTGAAAACACCGCAAAACTTCAGGCCGAG
ATGAAAAAAGTGGGTGTGCT

Downstream 100 bases:

>100_bases
GTCCTGTGCGGCATTCGGCATTGATATATCTGACGCTGGATCTGGTCGGCGGCACCGAGAAGGCCAAGGCACTTTTGGCT
AAATTGTCAGAGTGTGGAGA

Product: hypothetical protein

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKKIKIGLMGSAGRMGQEIAGVIEANPRCELVYAPLRGEKWDSKKAQAVDVWIDFTSPEALKDILKKASETKTPVVCGTT
GFSKKEKELLKTYSKKIPVLWSSNMSLGVAVLNEALKAFSAISHFDFQIEEIHHNRKKDRPSGTAITLQENLEKAVDKKL
PEALAIRGGGVFGVHKIFAMSDEEVLTFEHTALNRTVFAKGSVQAAEWLVKQKPGLYQIRDVLFGKSKK

Sequences:

>Translated_229_residues
MKKIKIGLMGSAGRMGQEIAGVIEANPRCELVYAPLRGEKWDSKKAQAVDVWIDFTSPEALKDILKKASETKTPVVCGTT
GFSKKEKELLKTYSKKIPVLWSSNMSLGVAVLNEALKAFSAISHFDFQIEEIHHNRKKDRPSGTAITLQENLEKAVDKKL
PEALAIRGGGVFGVHKIFAMSDEEVLTFEHTALNRTVFAKGSVQAAEWLVKQKPGLYQIRDVLFGKSKK
>Mature_229_residues
MKKIKIGLMGSAGRMGQEIAGVIEANPRCELVYAPLRGEKWDSKKAQAVDVWIDFTSPEALKDILKKASETKTPVVCGTT
GFSKKEKELLKTYSKKIPVLWSSNMSLGVAVLNEALKAFSAISHFDFQIEEIHHNRKKDRPSGTAITLQENLEKAVDKKL
PEALAIRGGGVFGVHKIFAMSDEEVLTFEHTALNRTVFAKGSVQAAEWLVKQKPGLYQIRDVLFGKSKK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=264, Percent_Identity=28.4090909090909, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_BDEBA (Q6MRM8)

Other databases:

- EMBL:   BX842646
- RefSeq:   NP_967075.1
- ProteinModelPortal:   Q6MRM8
- SMR:   Q6MRM8
- GeneID:   2733554
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd0047
- NMPDR:   fig|264462.1.peg.45
- HOGENOM:   HBG594002
- OMA:   GALKACE
- PhylomeDB:   Q6MRM8
- BioCyc:   BBAC264462:BD0047-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 25371; Mature: 25371

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS01298 DAPB; PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIKIGLMGSAGRMGQEIAGVIEANPRCELVYAPLRGEKWDSKKAQAVDVWIDFTSPEA
CCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCHHH
LKDILKKASETKTPVVCGTTGFSKKEKELLKTYSKKIPVLWSSNMSLGVAVLNEALKAFS
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
AISHFDFQIEEIHHNRKKDRPSGTAITLQENLEKAVDKKLPEALAIRGGGVFGVHKIFAM
HHHHCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCHHEEECCCCEEHHHHEEEC
SDEEVLTFEHTALNRTVFAKGSVQAAEWLVKQKPGLYQIRDVLFGKSKK
CCCCEEEEEHHHCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKIKIGLMGSAGRMGQEIAGVIEANPRCELVYAPLRGEKWDSKKAQAVDVWIDFTSPEA
CCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCHHH
LKDILKKASETKTPVVCGTTGFSKKEKELLKTYSKKIPVLWSSNMSLGVAVLNEALKAFS
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
AISHFDFQIEEIHHNRKKDRPSGTAITLQENLEKAVDKKLPEALAIRGGGVFGVHKIFAM
HHHHCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHCCHHEEECCCCEEHHHHEEEC
SDEEVLTFEHTALNRTVFAKGSVQAAEWLVKQKPGLYQIRDVLFGKSKK
CCCCEEEEEHHHCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA