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The map label for this gene is norR

Identifier: 38637907

GI number: 38637907

Start: 260063

End: 261607

Strand: Direct

Name: norR

Synonym: PHG246

Alternate gene names: 38637907

Gene position: 260063-261607 (Clockwise)

Preceding gene: 38637899

Following gene: 38637914

Centisome position: 57.52

GC content: 70.16

Gene sequence:

>1545_bases
ATGACGCCCATGTATCCCGAGTTGCTGACCGACCTGGTCACCGACCTGCCGCATGCGGTGCGCCTGCAGCGGCTGGTCAG
CGGACTACGCACGCATTTCCGTTGCGGTGCGGTGGCGCTGCTGCGGCTGGAAGAAGAACACCTGCGGCCGGTGGCGGTCG
ACGGGCTGGTGCGCGATACGCTCGGGCGGCGCTTTGCGGTGAGCCTGCACCCGCGGCTTGCCGCCATCCTCGCGCGGCGC
GACGTCACCTGCTTCCATCACGACAGCATGTTGCCCGACCCCTACGACGGGCTGATCGACGAACACGTTGGTGAGCCGCT
GCCGGTGCACGACTGCATGGGCACGAGCCTGCATTTGGACGGAAGGCCATGGGGCGTGCTGACGCTCGACGCGCTCACGG
TCGGCACGTTCGACGCCGCCGCGCAGGCCGAGCTGCAACGGCTGACCGTGATCGTCGAAGCCGCCATCCGCACCACCCGG
CTGGAGGCCGAGATCCGCGCCCTGCAGTTGGCGCGTGGCAAACAGCCAGACGGTGAAGGGCCGGCCGACGACGGCGAGAT
CATCGGCCAGAGCCAGGCCATTGCCGGCCTGCTGCACGAGCTGGAGGTGGTGGCCGACACCGATCTGCCGGTGCTGCTGC
TGGGTGAAACCGGCGTCGGCAAGGAGCTGTTTGCGCACCGCCTGCACCGCCACTCGCGCCGGCGCGGGCATCCGCTGGTG
CACGTGAACTGCGCGGCGCTGCCCGAGTCGCTCGCCGAAAGCGAGCTGTTCGGCCACGCCCGCGGCGCGTTCTCCGGCGC
GACCGGTGAGCGTCCGGGCCGCTTCGAAGCCGCCGCCGGCGGCACCCTGTTCCTCGATGAAGTCGGCGAGCTGCCACTTT
CAATCCAGGCCAAGCTGCTGCGCACGCTGCAGAACGGCGAAATCCAGCGGCTGGGCTCGGACCGTCCGCGCCGCGTCAAC
GTGCGCGTGATCGCCGCCACCAATCGCAACCTGCGCGAGCACGTGCGCGACGGCTCGTTCCGCGCCGACCTGTTCCACCG
CCTGTCGGTCTATCCGATTCCGATCCCGCCGCTGCGCGAACGCGGCAACGATGTACTGCTGCTGGCGGGCCGCTTCCTCG
AACTCAACCGCGCACGGCTCGGCATGCGCAGCCTGCGCCTGTCGGCCGCCGCGCAGGACGCGCTGCGCCGTTACCGCTGG
CCAGGCAACGTGCGCGAACTCGAGCACGTGATCAGCCGCGCCGCGCTGCGTTGCGTGAGCCGCGGCGCGGACCGGAATGA
CATCGTGACGCTGGAGGCGGAACTGCTGGACCTGGACGGGCTGGAATTACCGGCAGGGTCAGCCCACCATGCCGCCGAGG
CGGCCATCGCGCACCCGGCGCTACCCACGGGCGCGACGCTGCGTGAGGCGGTGGAGCAGACGCAGCGAGCCTGCATCGAG
CAGGCGCTGCGCGCGCATGATGGCAGCTGGGCGAAGGCCGCGCGGCAGTTGGGCATGGATGCCAGCAATCTGCACAAGCT
GGCGAAGCGGTTGGGCAGCAAGTAG

Upstream 100 bases:

>100_bases
CCAAATAAAAACCGCGCTGGATCAATGGCTTACAAGACATACGGTCATATTTACCTTAAAATTCGCATGGTATATTTGAC
CCGGACCGGTATTTATCACC

Downstream 100 bases:

>100_bases
CAGGCTTGCCGTCGGGTCACATCCTGCTGTCATGCAGCGCGCCGCCGCTGAGATCTACCATCTCTGGCTTCACCTCGGCA
AAGCGCATCACTTGGCCGCC

Product: anaerobic nitric oxide reductase transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MTPMYPELLTDLVTDLPHAVRLQRLVSGLRTHFRCGAVALLRLEEEHLRPVAVDGLVRDTLGRRFAVSLHPRLAAILARR
DVTCFHHDSMLPDPYDGLIDEHVGEPLPVHDCMGTSLHLDGRPWGVLTLDALTVGTFDAAAQAELQRLTVIVEAAIRTTR
LEAEIRALQLARGKQPDGEGPADDGEIIGQSQAIAGLLHELEVVADTDLPVLLLGETGVGKELFAHRLHRHSRRRGHPLV
HVNCAALPESLAESELFGHARGAFSGATGERPGRFEAAAGGTLFLDEVGELPLSIQAKLLRTLQNGEIQRLGSDRPRRVN
VRVIAATNRNLREHVRDGSFRADLFHRLSVYPIPIPPLRERGNDVLLLAGRFLELNRARLGMRSLRLSAAAQDALRRYRW
PGNVRELEHVISRAALRCVSRGADRNDIVTLEAELLDLDGLELPAGSAHHAAEAAIAHPALPTGATLREAVEQTQRACIE
QALRAHDGSWAKAARQLGMDASNLHKLAKRLGSK

Sequences:

>Translated_514_residues
MTPMYPELLTDLVTDLPHAVRLQRLVSGLRTHFRCGAVALLRLEEEHLRPVAVDGLVRDTLGRRFAVSLHPRLAAILARR
DVTCFHHDSMLPDPYDGLIDEHVGEPLPVHDCMGTSLHLDGRPWGVLTLDALTVGTFDAAAQAELQRLTVIVEAAIRTTR
LEAEIRALQLARGKQPDGEGPADDGEIIGQSQAIAGLLHELEVVADTDLPVLLLGETGVGKELFAHRLHRHSRRRGHPLV
HVNCAALPESLAESELFGHARGAFSGATGERPGRFEAAAGGTLFLDEVGELPLSIQAKLLRTLQNGEIQRLGSDRPRRVN
VRVIAATNRNLREHVRDGSFRADLFHRLSVYPIPIPPLRERGNDVLLLAGRFLELNRARLGMRSLRLSAAAQDALRRYRW
PGNVRELEHVISRAALRCVSRGADRNDIVTLEAELLDLDGLELPAGSAHHAAEAAIAHPALPTGATLREAVEQTQRACIE
QALRAHDGSWAKAARQLGMDASNLHKLAKRLGSK
>Mature_513_residues
TPMYPELLTDLVTDLPHAVRLQRLVSGLRTHFRCGAVALLRLEEEHLRPVAVDGLVRDTLGRRFAVSLHPRLAAILARRD
VTCFHHDSMLPDPYDGLIDEHVGEPLPVHDCMGTSLHLDGRPWGVLTLDALTVGTFDAAAQAELQRLTVIVEAAIRTTRL
EAEIRALQLARGKQPDGEGPADDGEIIGQSQAIAGLLHELEVVADTDLPVLLLGETGVGKELFAHRLHRHSRRRGHPLVH
VNCAALPESLAESELFGHARGAFSGATGERPGRFEAAAGGTLFLDEVGELPLSIQAKLLRTLQNGEIQRLGSDRPRRVNV
RVIAATNRNLREHVRDGSFRADLFHRLSVYPIPIPPLRERGNDVLLLAGRFLELNRARLGMRSLRLSAAAQDALRRYRWP
GNVRELEHVISRAALRCVSRGADRNDIVTLEAELLDLDGLELPAGSAHHAAEAAIAHPALPTGATLREAVEQTQRACIEQ
ALRAHDGSWAKAARQLGMDASNLHKLAKRLGSK

Specific function: Required for the nitric oxide (NO) induced expression of NO reductase. Not required for expression of 2 other pathway members, nitrate reductase (nirS) and nitrous oxide reductase (nosZ)

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain

Homologues:

Organism=Escherichia coli, GI87082152, Length=498, Percent_Identity=48.995983935743, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI87082117, Length=340, Percent_Identity=47.0588235294118, Blast_Score=261, Evalue=8e-71,
Organism=Escherichia coli, GI1789087, Length=331, Percent_Identity=43.8066465256798, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1788550, Length=373, Percent_Identity=38.0697050938338, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1790299, Length=397, Percent_Identity=38.0352644836272, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1790437, Length=341, Percent_Identity=41.3489736070381, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789233, Length=327, Percent_Identity=37.9204892966361, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI87081872, Length=330, Percent_Identity=38.1818181818182, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1788905, Length=324, Percent_Identity=39.8148148148148, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1786524, Length=248, Percent_Identity=46.7741935483871, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1787583, Length=319, Percent_Identity=36.0501567398119, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789828, Length=235, Percent_Identity=37.0212765957447, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI87081858, Length=220, Percent_Identity=35, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NORR1_CUPNH (Q9K4V0)

Other databases:

- EMBL:   AJ278371
- EMBL:   AY305378
- RefSeq:   NP_942881.1
- ProteinModelPortal:   Q9K4V0
- SMR:   Q9K4V0
- GeneID:   2656473
- GenomeReviews:   AY305378_GR
- KEGG:   reh:PHG246
- HOGENOM:   HBG740884
- OMA:   TRLEHEN
- PhylomeDB:   Q9K4V0
- ProtClustDB:   PRK05022
- BioCyc:   REUT381666:PHG246-MONOMER
- GO:   GO:0005622
- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- SMART:   SM00382
- SMART:   SM00065

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 56303; Mature: 56172

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00675 SIGMA54_INTERACT_1; PS00676 SIGMA54_INTERACT_2; PS00688 SIGMA54_INTERACT_3; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPMYPELLTDLVTDLPHAVRLQRLVSGLRTHFRCGAVALLRLEEEHLRPVAVDGLVRDT
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHCCCHHHHHHHHHH
LGRRFAVSLHPRLAAILARRDVTCFHHDSMLPDPYDGLIDEHVGEPLPVHDCMGTSLHLD
HCCEEEEEHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHCCCCCCHHHHCCCEEEEC
GRPWGVLTLDALTVGTFDAAAQAELQRLTVIVEAAIRTTRLEAEIRALQLARGKQPDGEG
CCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PADDGEIIGQSQAIAGLLHELEVVADTDLPVLLLGETGVGKELFAHRLHRHSRRRGHPLV
CCCCCHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEE
HVNCAALPESLAESELFGHARGAFSGATGERPGRFEAAAGGTLFLDEVGELPLSIQAKLL
EEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEEEHHHCCCCHHHHHHHH
RTLQNGEIQRLGSDRPRRVNVRVIAATNRNLREHVRDGSFRADLFHRLSVYPIPIPPLRE
HHHHCCCHHHCCCCCCCEEEEEEEEECCCHHHHHHCCCCHHHHHHHHCEECCCCCCHHHH
RGNDVLLLAGRFLELNRARLGMRSLRLSAAAQDALRRYRWPGNVRELEHVISRAALRCVS
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RGADRNDIVTLEAELLDLDGLELPAGSAHHAAEAAIAHPALPTGATLREAVEQTQRACIE
CCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
QALRAHDGSWAKAARQLGMDASNLHKLAKRLGSK
HHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPMYPELLTDLVTDLPHAVRLQRLVSGLRTHFRCGAVALLRLEEEHLRPVAVDGLVRDT
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHCCCHHHHHHHHHH
LGRRFAVSLHPRLAAILARRDVTCFHHDSMLPDPYDGLIDEHVGEPLPVHDCMGTSLHLD
HCCEEEEEHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHCCCCCCHHHHCCCEEEEC
GRPWGVLTLDALTVGTFDAAAQAELQRLTVIVEAAIRTTRLEAEIRALQLARGKQPDGEG
CCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PADDGEIIGQSQAIAGLLHELEVVADTDLPVLLLGETGVGKELFAHRLHRHSRRRGHPLV
CCCCCHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEE
HVNCAALPESLAESELFGHARGAFSGATGERPGRFEAAAGGTLFLDEVGELPLSIQAKLL
EEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCEEEEHHHCCCCHHHHHHHH
RTLQNGEIQRLGSDRPRRVNVRVIAATNRNLREHVRDGSFRADLFHRLSVYPIPIPPLRE
HHHHCCCHHHCCCCCCCEEEEEEEEECCCHHHHHHCCCCHHHHHHHHCEECCCCCCHHHH
RGNDVLLLAGRFLELNRARLGMRSLRLSAAAQDALRRYRWPGNVRELEHVISRAALRCVS
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RGADRNDIVTLEAELLDLDGLELPAGSAHHAAEAAIAHPALPTGATLREAVEQTQRACIE
CCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
QALRAHDGSWAKAARQLGMDASNLHKLAKRLGSK
HHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11069685; 12948488