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The map label for this gene is ccmB [H]

Identifier: 38637879

GI number: 38637879

Start: 232483

End: 233160

Strand: Direct

Name: ccmB [H]

Synonym: PHG215

Alternate gene names: 38637879

Gene position: 232483-233160 (Clockwise)

Preceding gene: 38637878

Following gene: 38637880

Centisome position: 51.42

GC content: 70.21

Gene sequence:

>678_bases
ATGACCCGCACCCTGGCCGCCATCATCATGCACGACCTGTCGCTTTCGTGGCGACGGCGCGGCAGCCTGCTCGGCAGCGT
GGTGTTCTTCGTGATCGCCACCAGCCTGTTCCCGCTGGCCGTCGGGCCCGACCTGCAGCAGCTGCGCGCCCTTGCGCCCG
GCATCCTGTGGGTGGCAGCGCTGCTGGCATCGATGCTGTCGCTGTCGCGGCTCTTCTCGCAGGAGTACGCCGACGGCAGT
CTCGATCAGCTGCTGCTGTCGCCGCATCCGCTGGCGCTGCTGGTGCTGGCCAAGATCTGTGCGCACTGGCTGACCAGCGG
GCTGCCGCTGCTGCTGTTGACGCCATTGCTCGCCCAGCAATACAGCCTGCCGGCAGGTTCTTCGTTTCTGCTTGCAGCGT
CGCTGCTGGTGGGCACGCCGGCGCTCAGCCTGATCGGCGCGGTCGGCGCCGCGCTCACGCTGGGCGTGCGCGGCGGTACC
GTCCTGCTCTGCATTCTGGTGCTGCCCCTGTGCGTGCCGGTGCTGGTATTCGGCGCCAGCGCCGGCGCCGGCGCCGACGC
CGGGCTCGAGGTGCTGCCGCAGTTCTCGCTGCTCGGCGCCTGCCTGGCCTTGTCATTGTTCCTGTGCCCGCTGGCCACCG
CCGCCGGGCTGCGCACCGCCATGGAGTCGTCCGGATGA

Upstream 100 bases:

>100_bases
AGGCACAGCTCGACGATCACCTGCGCGCGGGCGGCATGGCCATCGTCGCCACGCACGCGCTGCTGCCGGGCGCCAGGACC
TTAAGGCTGGACGCCCGGTC

Downstream 100 bases:

>100_bases
GCCCCCCGCTCAACCCAGCGCATGGCGGCAACGCTGCGCCACCTGCGCTGCGCTCCCGCTGGCTGGCCTACGCCGCGCCA
GTCCGCTTCTATCCGCTGGC

Product: ABC heme export system

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTRTLAAIIMHDLSLSWRRRGSLLGSVVFFVIATSLFPLAVGPDLQQLRALAPGILWVAALLASMLSLSRLFSQEYADGS
LDQLLLSPHPLALLVLAKICAHWLTSGLPLLLLTPLLAQQYSLPAGSSFLLAASLLVGTPALSLIGAVGAALTLGVRGGT
VLLCILVLPLCVPVLVFGASAGAGADAGLEVLPQFSLLGACLALSLFLCPLATAAGLRTAMESSG

Sequences:

>Translated_225_residues
MTRTLAAIIMHDLSLSWRRRGSLLGSVVFFVIATSLFPLAVGPDLQQLRALAPGILWVAALLASMLSLSRLFSQEYADGS
LDQLLLSPHPLALLVLAKICAHWLTSGLPLLLLTPLLAQQYSLPAGSSFLLAASLLVGTPALSLIGAVGAALTLGVRGGT
VLLCILVLPLCVPVLVFGASAGAGADAGLEVLPQFSLLGACLALSLFLCPLATAAGLRTAMESSG
>Mature_224_residues
TRTLAAIIMHDLSLSWRRRGSLLGSVVFFVIATSLFPLAVGPDLQQLRALAPGILWVAALLASMLSLSRLFSQEYADGSL
DQLLLSPHPLALLVLAKICAHWLTSGLPLLLLTPLLAQQYSLPAGSSFLLAASLLVGTPALSLIGAVGAALTLGVRGGTV
LLCILVLPLCVPVLVFGASAGAGADAGLEVLPQFSLLGACLALSLFLCPLATAAGLRTAMESSG

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=211, Percent_Identity=46.9194312796209, Blast_Score=134, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23104; Mature: 22973

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTLAAIIMHDLSLSWRRRGSLLGSVVFFVIATSLFPLAVGPDLQQLRALAPGILWVAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHH
LLASMLSLSRLFSQEYADGSLDQLLLSPHPLALLVLAKICAHWLTSGLPLLLLTPLLAQQ
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YSLPAGSSFLLAASLLVGTPALSLIGAVGAALTLGVRGGTVLLCILVLPLCVPVLVFGAS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
AGAGADAGLEVLPQFSLLGACLALSLFLCPLATAAGLRTAMESSG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRTLAAIIMHDLSLSWRRRGSLLGSVVFFVIATSLFPLAVGPDLQQLRALAPGILWVAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHH
LLASMLSLSRLFSQEYADGSLDQLLLSPHPLALLVLAKICAHWLTSGLPLLLLTPLLAQQ
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YSLPAGSSFLLAASLLVGTPALSLIGAVGAALTLGVRGGTVLLCILVLPLCVPVLVFGAS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
AGAGADAGLEVLPQFSLLGACLALSLFLCPLATAAGLRTAMESSG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]