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The map label for this gene is hypE2 [H]

Identifier: 38637741

GI number: 38637741

Start: 71583

End: 72650

Strand: Direct

Name: hypE2 [H]

Synonym: PHG076

Alternate gene names: 38637741

Gene position: 71583-72650 (Clockwise)

Preceding gene: 38637740

Following gene: 38637742

Centisome position: 15.83

GC content: 69.76

Gene sequence:

>1068_bases
ATGAATGACCGTGTTCCGGTCCCGCCGGCACGCGCGGCGCGCGTGCGGGACACGACCATCAACCTGACCCACGGAAGCGG
CGGCCGAGCGATGCGAGACCTGATCGAAGACGTGTTCGTGAGCACCTTCGACAATCCCGCGCTGGCCGCGCTAGAGGACC
AGGCTGTGTTCCCGCTGGTCAGCCTGGCAGCCCACGGCGACCGGCTGGCCTTTACCACCGACAGCTACGTGGTAGATCCG
CTGTTCTTTCCCGGCGGCGACATCGGTACGCTTGCCGCGGCGGGAACCGTGAACGACCTCGCGGTGTGCGGCGCGACGCC
GCTGTTCCTGTCGTGCGGCGTGGTGCTGGAGGAAGGCTTGCCGGTCGACACCTTGCGCCGGGTCGCGGCCAGCATGCAGC
GCGTCGCGCGGGCAGCCGGCGTCGCGATCGTCACGGGCGACACCAAGGTGGTCGAGCGCGGCAGCGCGGACAAGCTGTTT
ATCAATACGGCCGGGATCGGCGTGGTGCGCGCGGGGCTATCGATCTCCGCGCGCCATGCGCGTGCGGGAGACGTGGTTCT
CGTCAATGGCTATCTTGGCGACCATGGCGCGGCGATCCTGGTGGCCCGCCAGCAACTCGCACTTGAGGCCGACCTGCAAA
GCGACTGCCGCCCGCTCAACGGGCTGGTCGCCGCGATGCTCGACGCCTGCCCCGATATCCACTGCTTGCGCGACGCCACG
CGCGGCGGCGTGGCGACAGTGCTCAACGAGTTCGCGCAGGCCTCCGGCGTGGCCATCCGCATCCGCGAGGTGGACGTGCC
GCTGCGCGAGGCTGTCAAGGGAGCGTGCGAGATCCTCGGGCTGGATCCGCTGTACCTGGCCAACGAAGGCATCCTGGTGG
CCATAGTGCCGCCGGAGGATGCCGCGCGCGTGCTGGCGGCCATGCGCGCGCATCCTGATGGCAGGCAGGCGGCGGCCATC
GGCGAAGTGGAGCCGGGGCCGGCGGGGCTGGTGGTTCTGCACACCGGCTTTGGCGGGCAGCGGGTTGTGGACATGCTGGT
GGGCGAGCAGCTGCCGCGGATCTGCTGA

Upstream 100 bases:

>100_bases
ATCGACACCTCCCGGCTCGGGCGACATGGCGCGCGAGCGGCCGGGCAAACGGCAACCAGGGATGCGGTTGCCAACGAGCG
GGCCGCAGCCGGAGCCGGCC

Downstream 100 bases:

>100_bases
GTGGCCGCACCCGGTGGACAGCAAGCGAAGGCCGACATGCACGAACTAAGTATCGCGAACAGCGTGGTCGAGATCTGTGC
CGAGCAGGCGCGGGGCGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MNDRVPVPPARAARVRDTTINLTHGSGGRAMRDLIEDVFVSTFDNPALAALEDQAVFPLVSLAAHGDRLAFTTDSYVVDP
LFFPGGDIGTLAAAGTVNDLAVCGATPLFLSCGVVLEEGLPVDTLRRVAASMQRVARAAGVAIVTGDTKVVERGSADKLF
INTAGIGVVRAGLSISARHARAGDVVLVNGYLGDHGAAILVARQQLALEADLQSDCRPLNGLVAAMLDACPDIHCLRDAT
RGGVATVLNEFAQASGVAIRIREVDVPLREAVKGACEILGLDPLYLANEGILVAIVPPEDAARVLAAMRAHPDGRQAAAI
GEVEPGPAGLVVLHTGFGGQRVVDMLVGEQLPRIC

Sequences:

>Translated_355_residues
MNDRVPVPPARAARVRDTTINLTHGSGGRAMRDLIEDVFVSTFDNPALAALEDQAVFPLVSLAAHGDRLAFTTDSYVVDP
LFFPGGDIGTLAAAGTVNDLAVCGATPLFLSCGVVLEEGLPVDTLRRVAASMQRVARAAGVAIVTGDTKVVERGSADKLF
INTAGIGVVRAGLSISARHARAGDVVLVNGYLGDHGAAILVARQQLALEADLQSDCRPLNGLVAAMLDACPDIHCLRDAT
RGGVATVLNEFAQASGVAIRIREVDVPLREAVKGACEILGLDPLYLANEGILVAIVPPEDAARVLAAMRAHPDGRQAAAI
GEVEPGPAGLVVLHTGFGGQRVVDMLVGEQLPRIC
>Mature_355_residues
MNDRVPVPPARAARVRDTTINLTHGSGGRAMRDLIEDVFVSTFDNPALAALEDQAVFPLVSLAAHGDRLAFTTDSYVVDP
LFFPGGDIGTLAAAGTVNDLAVCGATPLFLSCGVVLEEGLPVDTLRRVAASMQRVARAAGVAIVTGDTKVVERGSADKLF
INTAGIGVVRAGLSISARHARAGDVVLVNGYLGDHGAAILVARQQLALEADLQSDCRPLNGLVAAMLDACPDIHCLRDAT
RGGVATVLNEFAQASGVAIRIREVDVPLREAVKGACEILGLDPLYLANEGILVAIVPPEDAARVLAAMRAHPDGRQAAAI
GEVEPGPAGLVVLHTGFGGQRVVDMLVGEQLPRIC

Specific function: May be involved in the maturation of the nifE hydrogenase [H]

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=338, Percent_Identity=55.3254437869823, Blast_Score=347, Evalue=5e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36860; Mature: 36860

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDRVPVPPARAARVRDTTINLTHGSGGRAMRDLIEDVFVSTFDNPALAALEDQAVFPLV
CCCCCCCCCCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHH
SLAAHGDRLAFTTDSYVVDPLFFPGGDIGTLAAAGTVNDLAVCGATPLFLSCGVVLEEGL
HHHCCCCEEEEEECCEEECCEECCCCCHHHHEECCCCHHHHHHCCCHHHHHCCHHHHCCC
PVDTLRRVAASMQRVARAAGVAIVTGDTKVVERGSADKLFINTAGIGVVRAGLSISARHA
CHHHHHHHHHHHHHHHHHCCEEEEECCHHHEECCCCCEEEEEECCCEEEECCCEEEECCC
RAGDVVLVNGYLGDHGAAILVARQQLALEADLQSDCRPLNGLVAAMLDACPDIHCLRDAT
CCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCC
RGGVATVLNEFAQASGVAIRIREVDVPLREAVKGACEILGLDPLYLANEGILVAIVPPED
CCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHEECCCCCEEECCCEEEEEECCCH
AARVLAAMRAHPDGRQAAAIGEVEPGPAGLVVLHTGFGGQRVVDMLVGEQLPRIC
HHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNDRVPVPPARAARVRDTTINLTHGSGGRAMRDLIEDVFVSTFDNPALAALEDQAVFPLV
CCCCCCCCCCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHH
SLAAHGDRLAFTTDSYVVDPLFFPGGDIGTLAAAGTVNDLAVCGATPLFLSCGVVLEEGL
HHHCCCCEEEEEECCEEECCEECCCCCHHHHEECCCCHHHHHHCCCHHHHHCCHHHHCCC
PVDTLRRVAASMQRVARAAGVAIVTGDTKVVERGSADKLFINTAGIGVVRAGLSISARHA
CHHHHHHHHHHHHHHHHHCCEEEEECCHHHEECCCCCEEEEEECCCEEEECCCEEEECCC
RAGDVVLVNGYLGDHGAAILVARQQLALEADLQSDCRPLNGLVAAMLDACPDIHCLRDAT
CCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCC
RGGVATVLNEFAQASGVAIRIREVDVPLREAVKGACEILGLDPLYLANEGILVAIVPPED
CCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHEECCCCCEEECCCEEEEEECCCH
AARVLAAMRAHPDGRQAAAIGEVEPGPAGLVVLHTGFGGQRVVDMLVGEQLPRIC
HHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1526470 [H]