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The map label for this gene is hypD2 [H]

Identifier: 38637740

GI number: 38637740

Start: 70379

End: 71590

Strand: Direct

Name: hypD2 [H]

Synonym: PHG075

Alternate gene names: 38637740

Gene position: 70379-71590 (Clockwise)

Preceding gene: 38637739

Following gene: 38637741

Centisome position: 15.57

GC content: 66.34

Gene sequence:

>1212_bases
ATGAAGTACGTCGACGAATTCCGCGATCCCGCCAAGGCGCAGGCGCTGGCGCGGGAAATCCGTGATCTGGTGGCAGGCAT
GGGCCGCGCCAGGCGGCGCCCGCTGCAGATCATGGAGGTGTGCGGCGGCCATACGCATACGATTTTCCGCTACGGCATCC
AGCAACTCTTGCCCGACGAGGTGGAGTTCGTGCATGGCCCGGGGTGCCCGGTATGCGTGCTGCCGATGGGGCGCGTCGAC
GACTGCGTGGCGCTGGCCGAGCGCCCCGAAGTGATATTCACAACGTTCGGCGACGCCATGCGCGTGCCCGGCTCCCGCAA
AAGCCTGCTCAAGGCCAAGGCGGATGGCGCCGATGTGCGGATGGTCTACTCGCCGATCGACGCGCTGGCGCTCGCGCGCA
ACCATCCGGACCGCGAAGTGATCTTCTTCGGCCTGGGCTTCGAGACCACCATGCCGAGCACCGCCATGACCGTTCTGCGC
GCGCGGGCCGAGGGCGTGCGCAACTTCTCGCTGTTCTGCAACCACATCACGATCATCCCGACCATCAAGGCCATTCTCGA
TTCACCTGACCTGCAGATCGACGGCTTCCTCGGTCCGGGCCATGTCAGCATGGTGATCGGCACGCAACCGTACGAGTTTA
TCGCCCGGCACTACCGCAAGCCGATCACCGTGGCGGGCTTCGAGCCGCTGGACGTGCTGCAGTCGATGTGGATGGTCCTC
AGGCAGATCGCGCAGGGCCGCTGCGAAGTGGAGAACCAGTACGGACGGATCGTGCCGGCAGCGGGCAATGCGCAGGCGCT
GGCGGCGATTCAGGAAGTGTTCGAGCTGCGCGAGTTCTTCGAATGGCGCGGACTGGGCTCGATCGACTTCTCGGGTGTGC
GGATGCGCGAGGCATTCTCCGCGTTCGACGCCGAGCGCAAGTTCACCGTGCCCGACGTCAAGATCGCCGACCCCAAGGCC
TGCCAGTGCGGCGAGGTGCTCAAGGGCGTGATCAAGCCCCATCAATGCAAGGTGTTCGGCACCGCCTGCACGCCGGAGTC
GCCGCTGGGGTCGCTGATGGTCTCGAGCGAGGGCGCCTGCGCGGCGTACTACCATTACTGCCGCATCGACACCTCCCGGC
TCGGGCGACATGGCGCGCGAGCGGCCGGGCAAACGGCAACCAGGGATGCGGTTGCCAACGAGCGGGCCGCAGCCGGAGCC
GGCCATGAATGA

Upstream 100 bases:

>100_bases
GGGTGCAGGAAACCCATGTTGCGATCTACCACATCCTGTGGGATCTGGTGCACACGTTGCTCGCCGAGGACCGCGGCGGG
CTGGCCGCAGGAGGCGCGCG

Downstream 100 bases:

>100_bases
CCGTGTTCCGGTCCCGCCGGCACGCGCGGCGCGCGTGCGGGACACGACCATCAACCTGACCCACGGAAGCGGCGGCCGAG
CGATGCGAGACCTGATCGAA

Product: HypD2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MKYVDEFRDPAKAQALAREIRDLVAGMGRARRRPLQIMEVCGGHTHTIFRYGIQQLLPDEVEFVHGPGCPVCVLPMGRVD
DCVALAERPEVIFTTFGDAMRVPGSRKSLLKAKADGADVRMVYSPIDALALARNHPDREVIFFGLGFETTMPSTAMTVLR
ARAEGVRNFSLFCNHITIIPTIKAILDSPDLQIDGFLGPGHVSMVIGTQPYEFIARHYRKPITVAGFEPLDVLQSMWMVL
RQIAQGRCEVENQYGRIVPAAGNAQALAAIQEVFELREFFEWRGLGSIDFSGVRMREAFSAFDAERKFTVPDVKIADPKA
CQCGEVLKGVIKPHQCKVFGTACTPESPLGSLMVSSEGACAAYYHYCRIDTSRLGRHGARAAGQTATRDAVANERAAAGA
GHE

Sequences:

>Translated_403_residues
MKYVDEFRDPAKAQALAREIRDLVAGMGRARRRPLQIMEVCGGHTHTIFRYGIQQLLPDEVEFVHGPGCPVCVLPMGRVD
DCVALAERPEVIFTTFGDAMRVPGSRKSLLKAKADGADVRMVYSPIDALALARNHPDREVIFFGLGFETTMPSTAMTVLR
ARAEGVRNFSLFCNHITIIPTIKAILDSPDLQIDGFLGPGHVSMVIGTQPYEFIARHYRKPITVAGFEPLDVLQSMWMVL
RQIAQGRCEVENQYGRIVPAAGNAQALAAIQEVFELREFFEWRGLGSIDFSGVRMREAFSAFDAERKFTVPDVKIADPKA
CQCGEVLKGVIKPHQCKVFGTACTPESPLGSLMVSSEGACAAYYHYCRIDTSRLGRHGARAAGQTATRDAVANERAAAGA
GHE
>Mature_403_residues
MKYVDEFRDPAKAQALAREIRDLVAGMGRARRRPLQIMEVCGGHTHTIFRYGIQQLLPDEVEFVHGPGCPVCVLPMGRVD
DCVALAERPEVIFTTFGDAMRVPGSRKSLLKAKADGADVRMVYSPIDALALARNHPDREVIFFGLGFETTMPSTAMTVLR
ARAEGVRNFSLFCNHITIIPTIKAILDSPDLQIDGFLGPGHVSMVIGTQPYEFIARHYRKPITVAGFEPLDVLQSMWMVL
RQIAQGRCEVENQYGRIVPAAGNAQALAAIQEVFELREFFEWRGLGSIDFSGVRMREAFSAFDAERKFTVPDVKIADPKA
CQCGEVLKGVIKPHQCKVFGTACTPESPLGSLMVSSEGACAAYYHYCRIDTSRLGRHGARAAGQTATRDAVANERAAAGA
GHE

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=366, Percent_Identity=57.103825136612, Blast_Score=449, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 44245; Mature: 44245

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVDEFRDPAKAQALAREIRDLVAGMGRARRRPLQIMEVCGGHTHTIFRYGIQQLLPDE
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCH
VEFVHGPGCPVCVLPMGRVDDCVALAERPEVIFTTFGDAMRVPGSRKSLLKAKADGADVR
HHEEECCCCCEEEECCCCHHHHHHHHCCCCEEEEECCCHHCCCCCHHHHHHHCCCCCCEE
MVYSPIDALALARNHPDREVIFFGLGFETTMPSTAMTVLRARAEGVRNFSLFCNHITIIP
EEECHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCEEHHH
TIKAILDSPDLQIDGFLGPGHVSMVIGTQPYEFIARHYRKPITVAGFEPLDVLQSMWMVL
HHHHHHCCCCCEEECEECCCCEEEEECCCCHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
RQIAQGRCEVENQYGRIVPAAGNAQALAAIQEVFELREFFEWRGLGSIDFSGVRMREAFS
HHHHCCCCEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
AFDAERKFTVPDVKIADPKACQCGEVLKGVIKPHQCKVFGTACTPESPLGSLMVSSEGAC
HHCCCCCCCCCCCEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCCCCC
AAYYHYCRIDTSRLGRHGARAAGQTATRDAVANERAAAGAGHE
EEEHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKYVDEFRDPAKAQALAREIRDLVAGMGRARRRPLQIMEVCGGHTHTIFRYGIQQLLPDE
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCH
VEFVHGPGCPVCVLPMGRVDDCVALAERPEVIFTTFGDAMRVPGSRKSLLKAKADGADVR
HHEEECCCCCEEEECCCCHHHHHHHHCCCCEEEEECCCHHCCCCCHHHHHHHCCCCCCEE
MVYSPIDALALARNHPDREVIFFGLGFETTMPSTAMTVLRARAEGVRNFSLFCNHITIIP
EEECHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCEEHHH
TIKAILDSPDLQIDGFLGPGHVSMVIGTQPYEFIARHYRKPITVAGFEPLDVLQSMWMVL
HHHHHHCCCCCEEECEECCCCEEEEECCCCHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
RQIAQGRCEVENQYGRIVPAAGNAQALAAIQEVFELREFFEWRGLGSIDFSGVRMREAFS
HHHHCCCCEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
AFDAERKFTVPDVKIADPKACQCGEVLKGVIKPHQCKVFGTACTPESPLGSLMVSSEGAC
HHCCCCCCCCCCCEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCCCCC
AAYYHYCRIDTSRLGRHGARAAGQTATRDAVANERAAAGAGHE
EEEHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]