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The map label for this gene is gmhA [H]

Identifier: 38637739

GI number: 38637739

Start: 69693

End: 70382

Strand: Direct

Name: gmhA [H]

Synonym: PHG074

Alternate gene names: 38637739

Gene position: 69693-70382 (Clockwise)

Preceding gene: 38637738

Following gene: 38637740

Centisome position: 15.41

GC content: 67.54

Gene sequence:

>690_bases
ATGCCCGGGGAAACACCACTGCAAGGGCTGTATCCATTCCTGCACGGGGAGCGGCAGGACGGCGCCAGGCTTGACGCAGC
CTTACTCGCTTCCGTGCAGCAGAAGGCCAGCGACAGCATTGACGCCAAGCGCCGCTTCTTCGAGCAGAACGGGCCCGTGG
TGGTGGCGGTGGCCCAGGCAATTGCCTTGACCTACCGCAACGGCGGCCGGCTGTTTGCCATGGGCAACGGCGGGTCGAGC
TGCGACGCGGCGCATATCGCGGTGGAGTTCCTGCATCCCGTCACGGCGGGTCGGCCGGCGCTCGCGGCCGTCAACCTCGT
CGCGGATACGGCGATGATGACCGCAGTTGGGAACGACGTGGGCTTCGCCCACGTCTTCGTGCGCCAGCTGGTGGCGCAGG
CGAGGCGCGGCGACGCGCTGATCGGTGTCTCGACCAGCGGCAACTCGGAAAATCTGCTCGCGGCCTTCGCCAAGGGCAAG
GAGATGGGTCTGGCGACCATCGGCCTGTCTGGTCACGACGGCGGCCGCATGGCGGCGAGCGCGGACCTCGATCACTGCCT
GGTGGTGGACAGCGACAGCATTCACCGGGTGCAGGAAACCCATGTTGCGATCTACCACATCCTGTGGGATCTGGTGCACA
CGTTGCTCGCCGAGGACCGCGGCGGGCTGGCCGCAGGAGGCGCGCGATGA

Upstream 100 bases:

>100_bases
TGCGCGCGGGGTCGCCGGCCCCGCCATAGCGGGCGGGGGCAGGAGAACAGGGCGGGAGCAAGGCTGGGACGGCAGGAATC
ACGTAGCAAGGAGACGCGGC

Downstream 100 bases:

>100_bases
AGTACGTCGACGAATTCCGCGATCCCGCCAAGGCGCAGGCGCTGGCGCGGGAAATCCGTGATCTGGTGGCAGGCATGGGC
CGCGCCAGGCGGCGCCCGCT

Product: putative sedoheptulose 7-phosphate isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPGETPLQGLYPFLHGERQDGARLDAALLASVQQKASDSIDAKRRFFEQNGPVVVAVAQAIALTYRNGGRLFAMGNGGSS
CDAAHIAVEFLHPVTAGRPALAAVNLVADTAMMTAVGNDVGFAHVFVRQLVAQARRGDALIGVSTSGNSENLLAAFAKGK
EMGLATIGLSGHDGGRMAASADLDHCLVVDSDSIHRVQETHVAIYHILWDLVHTLLAEDRGGLAAGGAR

Sequences:

>Translated_229_residues
MPGETPLQGLYPFLHGERQDGARLDAALLASVQQKASDSIDAKRRFFEQNGPVVVAVAQAIALTYRNGGRLFAMGNGGSS
CDAAHIAVEFLHPVTAGRPALAAVNLVADTAMMTAVGNDVGFAHVFVRQLVAQARRGDALIGVSTSGNSENLLAAFAKGK
EMGLATIGLSGHDGGRMAASADLDHCLVVDSDSIHRVQETHVAIYHILWDLVHTLLAEDRGGLAAGGAR
>Mature_228_residues
PGETPLQGLYPFLHGERQDGARLDAALLASVQQKASDSIDAKRRFFEQNGPVVVAVAQAIALTYRNGGRLFAMGNGGSSC
DAAHIAVEFLHPVTAGRPALAAVNLVADTAMMTAVGNDVGFAHVFVRQLVAQARRGDALIGVSTSGNSENLLAAFAKGKE
MGLATIGLSGHDGGRMAASADLDHCLVVDSDSIHRVQETHVAIYHILWDLVHTLLAEDRGGLAAGGAR

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=158, Percent_Identity=39.2405063291139, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1789539, Length=153, Percent_Identity=30.718954248366, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 23901; Mature: 23770

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGETPLQGLYPFLHGERQDGARLDAALLASVQQKASDSIDAKRRFFEQNGPVVVAVAQA
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEHH
IALTYRNGGRLFAMGNGGSSCDAAHIAVEFLHPVTAGRPALAAVNLVADTAMMTAVGNDV
HHHEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
GFAHVFVRQLVAQARRGDALIGVSTSGNSENLLAAFAKGKEMGLATIGLSGHDGGRMAAS
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEC
ADLDHCLVVDSDSIHRVQETHVAIYHILWDLVHTLLAEDRGGLAAGGAR
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
PGETPLQGLYPFLHGERQDGARLDAALLASVQQKASDSIDAKRRFFEQNGPVVVAVAQA
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEHH
IALTYRNGGRLFAMGNGGSSCDAAHIAVEFLHPVTAGRPALAAVNLVADTAMMTAVGNDV
HHHEEECCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
GFAHVFVRQLVAQARRGDALIGVSTSGNSENLLAAFAKGKEMGLATIGLSGHDGGRMAAS
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCEEEC
ADLDHCLVVDSDSIHRVQETHVAIYHILWDLVHTLLAEDRGGLAAGGAR
CCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA