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The map label for this gene is glnM [H]

Identifier: 37681432

GI number: 37681432

Start: 3340707

End: 3341447

Strand: Direct

Name: glnM [H]

Synonym: VV3247

Alternate gene names: 37681432

Gene position: 3340707-3341447 (Clockwise)

Preceding gene: 161486583

Following gene: NA

Centisome position: 99.59

GC content: 46.42

Gene sequence:

>741_bases
GTGACCTATCGATATTTATGTTTAATGATGTTACTGCCACTCACTGGATGTTCTGACTATCAATGGGGCTGGTATGTGCT
TGATCCGACGACCGAGCAAGGCCTAACGAACGTGAAGTTTCTTATCGCTGGCTTTGCCGACACCATCAGCGTATCGCTAC
TCAGTATGCTGTTTGCCATGACTCTGGGCTTAATGGTTGCCCTACCGGCCCTTTCTCCCCGCAAATCCCTACAACGCTTA
AACCGGATTTACGTTGAAGTAATACGTGCCATTCCAGTATTGGTTCTGCTGTTGTGGGTGTATTACGGCCTACCCACATT
ACTCGATGTTTCACTAGACCATTATTGGGCAGGAATTATTGCACTGACGATCGCGGAAAGTGCGTTTATGGCAGAAGTGT
TTCGCGGTGGTATTCAATCTATCGGTCGTGGCCAACATGAAGCAGCAAAGTCGCTTGGTCTCAACTATTGGCAAAAAATG
CGCTTGGTGATTTTGCCGCAAGCATTTCGTCAGATGCTGCCCGCGCTCGGCAACCAGTTTGTTTATATTCTCAAAATGAG
CTCATTGGTCAGTGTCATTGGTCTGAGTGATTTGACAAGACGTGCCAATGAGTTGGTGGTGAATGAGTACTTACCACTAG
AGATTTATACTTTCTTAGTGTTGGAATATTTGCTGTTGATCTTGATGGTCTCTCAAGCTGTACGTTGGCTAGAAAAGCGC
AGTGCCATTCCCAGCCATTAG

Upstream 100 bases:

>100_bases
TCCTTTAACTTATTGTTCCGTAAATAGTTGAGATTTCGCGTTACATCATTGATAACATAGCAGCAACACAACCATTTTTT
TAGTTGATATAAGGTGTAGT

Downstream 100 bases:

>100_bases
TTCATCATCATCATAAAAAACGCCGCTATTGCAGCGGCGTTTTTGTTATCCAGCGATAATTACTTTTTCTTAACTGGGCG
TTGCCAGCCTGTAATTTTAC

Product: ABC-type glutamine transport system, permease component

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTYRYLCLMMLLPLTGCSDYQWGWYVLDPTTEQGLTNVKFLIAGFADTISVSLLSMLFAMTLGLMVALPALSPRKSLQRL
NRIYVEVIRAIPVLVLLLWVYYGLPTLLDVSLDHYWAGIIALTIAESAFMAEVFRGGIQSIGRGQHEAAKSLGLNYWQKM
RLVILPQAFRQMLPALGNQFVYILKMSSLVSVIGLSDLTRRANELVVNEYLPLEIYTFLVLEYLLLILMVSQAVRWLEKR
SAIPSH

Sequences:

>Translated_246_residues
MTYRYLCLMMLLPLTGCSDYQWGWYVLDPTTEQGLTNVKFLIAGFADTISVSLLSMLFAMTLGLMVALPALSPRKSLQRL
NRIYVEVIRAIPVLVLLLWVYYGLPTLLDVSLDHYWAGIIALTIAESAFMAEVFRGGIQSIGRGQHEAAKSLGLNYWQKM
RLVILPQAFRQMLPALGNQFVYILKMSSLVSVIGLSDLTRRANELVVNEYLPLEIYTFLVLEYLLLILMVSQAVRWLEKR
SAIPSH
>Mature_245_residues
TYRYLCLMMLLPLTGCSDYQWGWYVLDPTTEQGLTNVKFLIAGFADTISVSLLSMLFAMTLGLMVALPALSPRKSLQRLN
RIYVEVIRAIPVLVLLLWVYYGLPTLLDVSLDHYWAGIIALTIAESAFMAEVFRGGIQSIGRGQHEAAKSLGLNYWQKMR
LVILPQAFRQMLPALGNQFVYILKMSSLVSVIGLSDLTRRANELVVNEYLPLEIYTFLVLEYLLLILMVSQAVRWLEKRS
AIPSH

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787030, Length=207, Percent_Identity=34.2995169082126, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786873, Length=230, Percent_Identity=31.7391304347826, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788226, Length=197, Percent_Identity=36.0406091370558, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI87082239, Length=203, Percent_Identity=32.512315270936, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786874, Length=240, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788646, Length=206, Percent_Identity=28.6407766990291, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788645, Length=217, Percent_Identity=28.110599078341, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI48994930, Length=125, Percent_Identity=39.2, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787087, Length=217, Percent_Identity=21.6589861751152, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787086, Length=167, Percent_Identity=26.9461077844311, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27883; Mature: 27752

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure 
TYRYLCLMMLLPLTGCSDYQWGWYVLDPTTEQGLTNVKFLIAGFADTISVSLLSMLFAM
HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGLMVALPALSPRKSLQRLNRIYVEVIRAIPVLVLLLWVYYGLPTLLDVSLDHYWAGII
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALTIAESAFMAEVFRGGIQSIGRGQHEAAKSLGLNYWQKMRLVILPQAFRQMLPALGNQF
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHH
VYILKMSSLVSVIGLSDLTRRANELVVNEYLPLEIYTFLVLEYLLLILMVSQAVRWLEKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIPSH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]