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The map label for this gene is ydhC [H]

Identifier: 161486583

GI number: 161486583

Start: 3338549

End: 3339754

Strand: Direct

Name: ydhC [H]

Synonym: VV3246

Alternate gene names: 161486583

Gene position: 3338549-3339754 (Clockwise)

Preceding gene: 37681428

Following gene: 37681432

Centisome position: 99.52

GC content: 50.0

Gene sequence:

>1206_bases
ATGAACATTTCAAAATTACAGCTTGTGTATCTTGCAGCCCTCTCGATGCTCGGCTTTGTCGCAACAGACATGTATCTCCC
TGCGTTTAAAGCGATGGAAATCGACTTTATGACCGGACCAGAACAGATCGCGCTTTCCTTAACGGTCTTTTTGGTCGGCA
TGGCGGTCGGTCAACTGCTTTGGGGCCTTGCCTCTGATAAGTTTGGTCACCGCAATACCTTAGCAGCTGGCCTTGCTCTG
TTTACGCTGGCTTCATTAGGTTTGGCGTTCAGTGATCAAGTTTGGCAACTGCTCAGCTTACGTTTTGTGCAAGCGATCGG
GGTGTGTGCACCGGCGGTGATCTGGCAAGCCATGGTCATCAAACGTTACTCCAGCAGTAGCCAACAAATTTTTGCCACCA
TTATGCCGCTGGTAGCACTTTCTCCTGCGCTCGCCCCTCAGTTGGGTGTTGTGTTGGCTGATAGTTTTGGTTGGCACAGT
ATTTTTGTCGCGTTAACGGTACTCGGTTTGGTCTTGGTTGCGGCGACCATGGCACAACCTAGTGTCGCCAATGAGCCAAA
GCAAAGCAGTGTAACATCGGATATCAAACATCTACTCAGCTCAAAAACCTATTTGGGCAATGTAATGATGTTCGCCACCG
CGTCTGCCGCTTTCTTTGCTTACCTGACAGGTATGCCTGAAATCATGGCGCAGCTTGGCTACGATGCCAAAGACATTGGC
ATGAGCTTTGTGCCGCAAACCATCGCGTTTATGGTCGGTGGATACTTAGGTAAAGTTGGTGTGCGTAAATTTGGTGATGA
AAAAGTCCTGCGTCAACTGATTGGTCTGTTTAGCGTCGCAGCGCTGCTGATTTTCATCGCATCACAATGGCAATTAACGT
CTATTTGGCCAATCTTAGCGCCATTCTGTTTGATTGCCGTGGCGAATGGTGCCCTTTACCCTATCGTGGTTAACCGCGCA
CTTGCCAGTGCTAAGCAAAGCCCAGCCACAGCCGCAGGTTTGCAAAACAGCTTACAAATCACCGTCAGCAGCTTATCTAG
CGCGCTGGTCGCCGCCCTTGCTAGCCAAGCGCAAGCGGTTACCGGTATTGCGATTGTTCTCTGTATGGGCGGACTTTGGA
TCGGCTATATCGTCTCCAACAAAGAGTTGTCGCAGCACTTCACAACACCAGACAATGCACGCGTGGTGAGTGATGAAGAG
ATCTAA

Upstream 100 bases:

>100_bases
TTTCTCAAAAGCGAAAAATAGAATAGCAGGGCATATAAATCAGGGTTGGCGCCAACTGATCACAAAACATTTGTAGTGAA
AAAAATTGAATGGAATAACT

Downstream 100 bases:

>100_bases
TCTCTAGCAACACAAGAGCCGCATAATGAGTATGCGGCTCTATGTTTTGAGGCGAGGCTAACAACCAGTTATAGCCCTTT
TAGTCCCCATTTTTCTGCGG

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MNISKLQLVYLAALSMLGFVATDMYLPAFKAMEIDFMTGPEQIALSLTVFLVGMAVGQLLWGLASDKFGHRNTLAAGLAL
FTLASLGLAFSDQVWQLLSLRFVQAIGVCAPAVIWQAMVIKRYSSSSQQIFATIMPLVALSPALAPQLGVVLADSFGWHS
IFVALTVLGLVLVAATMAQPSVANEPKQSSVTSDIKHLLSSKTYLGNVMMFATASAAFFAYLTGMPEIMAQLGYDAKDIG
MSFVPQTIAFMVGGYLGKVGVRKFGDEKVLRQLIGLFSVAALLIFIASQWQLTSIWPILAPFCLIAVANGALYPIVVNRA
LASAKQSPATAAGLQNSLQITVSSLSSALVAALASQAQAVTGIAIVLCMGGLWIGYIVSNKELSQHFTTPDNARVVSDEE
I

Sequences:

>Translated_401_residues
MNISKLQLVYLAALSMLGFVATDMYLPAFKAMEIDFMTGPEQIALSLTVFLVGMAVGQLLWGLASDKFGHRNTLAAGLAL
FTLASLGLAFSDQVWQLLSLRFVQAIGVCAPAVIWQAMVIKRYSSSSQQIFATIMPLVALSPALAPQLGVVLADSFGWHS
IFVALTVLGLVLVAATMAQPSVANEPKQSSVTSDIKHLLSSKTYLGNVMMFATASAAFFAYLTGMPEIMAQLGYDAKDIG
MSFVPQTIAFMVGGYLGKVGVRKFGDEKVLRQLIGLFSVAALLIFIASQWQLTSIWPILAPFCLIAVANGALYPIVVNRA
LASAKQSPATAAGLQNSLQITVSSLSSALVAALASQAQAVTGIAIVLCMGGLWIGYIVSNKELSQHFTTPDNARVVSDEE
I
>Mature_401_residues
MNISKLQLVYLAALSMLGFVATDMYLPAFKAMEIDFMTGPEQIALSLTVFLVGMAVGQLLWGLASDKFGHRNTLAAGLAL
FTLASLGLAFSDQVWQLLSLRFVQAIGVCAPAVIWQAMVIKRYSSSSQQIFATIMPLVALSPALAPQLGVVLADSFGWHS
IFVALTVLGLVLVAATMAQPSVANEPKQSSVTSDIKHLLSSKTYLGNVMMFATASAAFFAYLTGMPEIMAQLGYDAKDIG
MSFVPQTIAFMVGGYLGKVGVRKFGDEKVLRQLIGLFSVAALLIFIASQWQLTSIWPILAPFCLIAVANGALYPIVVNRA
LASAKQSPATAAGLQNSLQITVSSLSSALVAALASQAQAVTGIAIVLCMGGLWIGYIVSNKELSQHFTTPDNARVVSDEE
I

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=356, Percent_Identity=46.0674157303371, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI1788509, Length=294, Percent_Identity=23.1292517006803, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790146, Length=236, Percent_Identity=22.0338983050847, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082312, Length=351, Percent_Identity=23.3618233618234, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787065, Length=265, Percent_Identity=23.0188679245283, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42583; Mature: 42583

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISKLQLVYLAALSMLGFVATDMYLPAFKAMEIDFMTGPEQIALSLTVFLVGMAVGQLL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHH
WGLASDKFGHRNTLAAGLALFTLASLGLAFSDQVWQLLSLRFVQAIGVCAPAVIWQAMVI
HHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYSSSSQQIFATIMPLVALSPALAPQLGVVLADSFGWHSIFVALTVLGLVLVAATMAQP
HHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCC
SVANEPKQSSVTSDIKHLLSSKTYLGNVMMFATASAAFFAYLTGMPEIMAQLGYDAKDIG
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHC
MSFVPQTIAFMVGGYLGKVGVRKFGDEKVLRQLIGLFSVAALLIFIASQWQLTSIWPILA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
PFCLIAVANGALYPIVVNRALASAKQSPATAAGLQNSLQITVSSLSSALVAALASQAQAV
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TGIAIVLCMGGLWIGYIVSNKELSQHFTTPDNARVVSDEEI
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEECCCCCC
>Mature Secondary Structure
MNISKLQLVYLAALSMLGFVATDMYLPAFKAMEIDFMTGPEQIALSLTVFLVGMAVGQLL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHH
WGLASDKFGHRNTLAAGLALFTLASLGLAFSDQVWQLLSLRFVQAIGVCAPAVIWQAMVI
HHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYSSSSQQIFATIMPLVALSPALAPQLGVVLADSFGWHSIFVALTVLGLVLVAATMAQP
HHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCC
SVANEPKQSSVTSDIKHLLSSKTYLGNVMMFATASAAFFAYLTGMPEIMAQLGYDAKDIG
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHC
MSFVPQTIAFMVGGYLGKVGVRKFGDEKVLRQLIGLFSVAALLIFIASQWQLTSIWPILA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
PFCLIAVANGALYPIVVNRALASAKQSPATAAGLQNSLQITVSSLSSALVAALASQAQAV
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TGIAIVLCMGGLWIGYIVSNKELSQHFTTPDNARVVSDEEI
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]