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The map label for this gene is ypdF [C]

Identifier: 37681385

GI number: 37681385

Start: 3287907

End: 3289694

Strand: Direct

Name: ypdF [C]

Synonym: VV3201

Alternate gene names: 37681385

Gene position: 3287907-3289694 (Clockwise)

Preceding gene: 37681384

Following gene: 37681394

Centisome position: 98.01

GC content: 51.96

Gene sequence:

>1788_bases
ATGCACAAATCAACTCACGAGCGTGTTGTTGCCATTCGCACTTGGTTGCAGCAACACAATATCGACGCCCTACTCGTCCC
ACACGAAGACGAATACCTAGGCGAATATGTTCCCGACCATAACGAACGCTTACATTGGCTAACTGGCTTTACCGGTTCCG
CCGGCGCTGCCGTTATCACCCAAGAAAAAGCCGCCATGTTTGTTGATGGTCGCTACACCGTTCAGGTGACCAAACAAGTT
CCTGCCGATTTGTTTGAGTATCGCCATTTGATTGAAGAGCCAGCTCTTGAATGGTTGCAAGAAAACCTCGCTCGTGGTGC
ATCTGTGGCCATTGACCCACGCATGCACAGCGCCGCTTGGCTAAACATGGCACAAGCGAAATTGGCGGGTGTGCTTGAGC
TTACCATTCTCGACAGCAATCCGATTGATGAGTTGTGGCATGATCGCCCACAACCTGTGGTTTCTGACGTTCGACTGATG
TCGACAGAGGCCGTCGGCCAAAGCTCTGCCGATAAACGCGCGAACATCGCACAGCTGATCACAAAGCAAGGCGTTGATAG
CGCCGTTATCACCGCGCTAGATTCGATTTGCTGGTTGCTCAACGTCCGCGGTTTGGACGTCTCTCGCTTACCAGTATTAC
TGTCCCACGCGATTCTGCATGCTGATGGCCAGGTAGAGTTCTTCCTCGATCCTGCTCGCTTACCTGAAGGGTTTGATGTT
CATGTCGGCCAAGGGGTGCACGTTTTCCATCCTGAGACGCTGCAAGCTCGCCTTGAAAGCTTGACGGGCAAAAAAGTTCT
GCTCGATGCCGGCACCAGTAACGCATGGTTTAAACTGGTTCTGCAAAACGCAGGCGCCGTCGTTGTCCCGGGTGCAGATC
CTTGTTTGATGCCGAAAGCCGCCAAAAATGCGGTTGAAATTTCCGGCATGAAAGCATGTCACCTGCGCGATGGTGCTGCG
ATGGTCAAGTTCCTAAGTTGGCTTGACGCACAAGTGGCACAAGGTATTTTGCACGATGAAGCAACTTTGGCCGACAAACT
GGAAGCCATTCGCCGCGAAGATCCCACTCTGAAGGATTTGAGTTTCGATACCATTTCGGCAGCCGGCAGCAACGCTGCGA
TGTGTCACTACAATCATCAAAACCAGCCTCAACCAGGCCAACTCAGCATGGATACGCTCTACTTAGTTGACTCTGGCGGC
CAATATCTAGATGGCACCACCGACATCACTCGTACGGTTGCCATCGGCCAACCTTCAGCAGAAATGATCAAGCAGTTTAC
TTTGGCTCTGAAAGGCCATATTGGTGTGGCTCGCGCTCGTTTCCCGAAAGGCACTCGTGGCTATCAAATTGATACCCTGG
CTCGTCAACACCTATGGGCGGAAGGCTACGACTATGATCATGGTACTGGTCACGGTGTGGGCCACTTCCTGAGCGTGCAT
GAAGGCCCAGCCAGCATTTCAAAACGTCAGATCGACGTGCCTCTTGTCGAAGGGATGGTGCTCTCTAACGAACCAGGTTA
CTACCGCGCGGACGCGTTTGGTATTCGTATCGAAAACTTGGAATTAGTGGTTGAGAAGCAAACCCAAGGTGACTTCCCTA
TCTTGACCTTTGAATCTCTGACTCGCTGTCCAATCGACAAACGTAACATCAATGTCGATATGCTCACGCGTCCTGAACTC
GCTTGGCTAAATGACTACCACCAAAAAGTGTGGGATGACATTAGCCCATTGGTTGAAGGTGACGCGCAAGTTTGGCTACG
TGAAGCGACGCTACCACTCAGCCACTGA

Upstream 100 bases:

>100_bases
GTCCTCCGGGCTCATCTATGGTCTGTGGTCCTTACATGGAAGATAAGGAGCAGCTCCCAACCTGAGCAAACGGAGCAAAA
AGAACAAAGGAATCGTACAG

Downstream 100 bases:

>100_bases
TAAGCAAATAGACACTGTCATTTGCAAACAATAGAAAAAGGGTTAAGGCAAAATGCCTTAACCCTTTTTGTTTCACGTGA
AACATATCCACATGCCACTT

Product: aminopeptidase P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MHKSTHERVVAIRTWLQQHNIDALLVPHEDEYLGEYVPDHNERLHWLTGFTGSAGAAVITQEKAAMFVDGRYTVQVTKQV
PADLFEYRHLIEEPALEWLQENLARGASVAIDPRMHSAAWLNMAQAKLAGVLELTILDSNPIDELWHDRPQPVVSDVRLM
STEAVGQSSADKRANIAQLITKQGVDSAVITALDSICWLLNVRGLDVSRLPVLLSHAILHADGQVEFFLDPARLPEGFDV
HVGQGVHVFHPETLQARLESLTGKKVLLDAGTSNAWFKLVLQNAGAVVVPGADPCLMPKAAKNAVEISGMKACHLRDGAA
MVKFLSWLDAQVAQGILHDEATLADKLEAIRREDPTLKDLSFDTISAAGSNAAMCHYNHQNQPQPGQLSMDTLYLVDSGG
QYLDGTTDITRTVAIGQPSAEMIKQFTLALKGHIGVARARFPKGTRGYQIDTLARQHLWAEGYDYDHGTGHGVGHFLSVH
EGPASISKRQIDVPLVEGMVLSNEPGYYRADAFGIRIENLELVVEKQTQGDFPILTFESLTRCPIDKRNINVDMLTRPEL
AWLNDYHQKVWDDISPLVEGDAQVWLREATLPLSH

Sequences:

>Translated_595_residues
MHKSTHERVVAIRTWLQQHNIDALLVPHEDEYLGEYVPDHNERLHWLTGFTGSAGAAVITQEKAAMFVDGRYTVQVTKQV
PADLFEYRHLIEEPALEWLQENLARGASVAIDPRMHSAAWLNMAQAKLAGVLELTILDSNPIDELWHDRPQPVVSDVRLM
STEAVGQSSADKRANIAQLITKQGVDSAVITALDSICWLLNVRGLDVSRLPVLLSHAILHADGQVEFFLDPARLPEGFDV
HVGQGVHVFHPETLQARLESLTGKKVLLDAGTSNAWFKLVLQNAGAVVVPGADPCLMPKAAKNAVEISGMKACHLRDGAA
MVKFLSWLDAQVAQGILHDEATLADKLEAIRREDPTLKDLSFDTISAAGSNAAMCHYNHQNQPQPGQLSMDTLYLVDSGG
QYLDGTTDITRTVAIGQPSAEMIKQFTLALKGHIGVARARFPKGTRGYQIDTLARQHLWAEGYDYDHGTGHGVGHFLSVH
EGPASISKRQIDVPLVEGMVLSNEPGYYRADAFGIRIENLELVVEKQTQGDFPILTFESLTRCPIDKRNINVDMLTRPEL
AWLNDYHQKVWDDISPLVEGDAQVWLREATLPLSH
>Mature_595_residues
MHKSTHERVVAIRTWLQQHNIDALLVPHEDEYLGEYVPDHNERLHWLTGFTGSAGAAVITQEKAAMFVDGRYTVQVTKQV
PADLFEYRHLIEEPALEWLQENLARGASVAIDPRMHSAAWLNMAQAKLAGVLELTILDSNPIDELWHDRPQPVVSDVRLM
STEAVGQSSADKRANIAQLITKQGVDSAVITALDSICWLLNVRGLDVSRLPVLLSHAILHADGQVEFFLDPARLPEGFDV
HVGQGVHVFHPETLQARLESLTGKKVLLDAGTSNAWFKLVLQNAGAVVVPGADPCLMPKAAKNAVEISGMKACHLRDGAA
MVKFLSWLDAQVAQGILHDEATLADKLEAIRREDPTLKDLSFDTISAAGSNAAMCHYNHQNQPQPGQLSMDTLYLVDSGG
QYLDGTTDITRTVAIGQPSAEMIKQFTLALKGHIGVARARFPKGTRGYQIDTLARQHLWAEGYDYDHGTGHGVGHFLSVH
EGPASISKRQIDVPLVEGMVLSNEPGYYRADAFGIRIENLELVVEKQTQGDFPILTFESLTRCPIDKRNINVDMLTRPEL
AWLNDYHQKVWDDISPLVEGDAQVWLREATLPLSH

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=606, Percent_Identity=38.1188118811881, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI264681565, Length=603, Percent_Identity=36.318407960199, Blast_Score=342, Evalue=5e-94,
Organism=Homo sapiens, GI93141226, Length=606, Percent_Identity=33.4983498349835, Blast_Score=337, Evalue=2e-92,
Organism=Escherichia coli, GI1788728, Length=192, Percent_Identity=31.7708333333333, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17509539, Length=613, Percent_Identity=35.2365415986949, Blast_Score=348, Evalue=4e-96,
Organism=Caenorhabditis elegans, GI25149105, Length=622, Percent_Identity=30.2250803858521, Blast_Score=266, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6322999, Length=660, Percent_Identity=31.6666666666667, Blast_Score=314, Evalue=2e-86,
Organism=Drosophila melanogaster, GI17137632, Length=591, Percent_Identity=36.7174280879865, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI161078230, Length=602, Percent_Identity=30.2325581395349, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI21357287, Length=602, Percent_Identity=30.2325581395349, Blast_Score=263, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 65764; Mature: 65764

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKSTHERVVAIRTWLQQHNIDALLVPHEDEYLGEYVPDHNERLHWLTGFTGSAGAAVIT
CCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCCCCEEEEEECCCCCCCCEEEE
QEKAAMFVDGRYTVQVTKQVPADLFEYRHLIEEPALEWLQENLARGASVAIDPRMHSAAW
ECCEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHH
LNMAQAKLAGVLELTILDSNPIDELWHDRPQPVVSDVRLMSTEAVGQSSADKRANIAQLI
HHHHHHHHCCEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TKQGVDSAVITALDSICWLLNVRGLDVSRLPVLLSHAILHADGQVEFFLDPARLPEGFDV
HHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCEE
HVGQGVHVFHPETLQARLESLTGKKVLLDAGTSNAWFKLVLQNAGAVVVPGADPCLMPKA
ECCCCEEEECCHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCEEEECCCCCCCCCHH
AKNAVEISGMKACHLRDGAAMVKFLSWLDAQVAQGILHDEATLADKLEAIRREDPTLKDL
HCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCC
SFDTISAAGSNAAMCHYNHQNQPQPGQLSMDTLYLVDSGGQYLDGTTDITRTVAIGQPSA
CCHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEECCCHH
EMIKQFTLALKGHIGVARARFPKGTRGYQIDTLARQHLWAEGYDYDHGTGHGVGHFLSVH
HHHHHHHHHHHCCCCCHHHCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEC
EGPASISKRQIDVPLVEGMVLSNEPGYYRADAFGIRIENLELVVEKQTQGDFPILTFESL
CCCCCCCCCCCCCCHHCCEEEECCCCEEEECEEEEEEECEEEEEEECCCCCCCEEEHHHH
TRCPIDKRNINVDMLTRPELAWLNDYHQKVWDDISPLVEGDAQVWLREATLPLSH
HCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCC
>Mature Secondary Structure
MHKSTHERVVAIRTWLQQHNIDALLVPHEDEYLGEYVPDHNERLHWLTGFTGSAGAAVIT
CCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCCCCEEEEEECCCCCCCCEEEE
QEKAAMFVDGRYTVQVTKQVPADLFEYRHLIEEPALEWLQENLARGASVAIDPRMHSAAW
ECCEEEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHH
LNMAQAKLAGVLELTILDSNPIDELWHDRPQPVVSDVRLMSTEAVGQSSADKRANIAQLI
HHHHHHHHCCEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TKQGVDSAVITALDSICWLLNVRGLDVSRLPVLLSHAILHADGQVEFFLDPARLPEGFDV
HHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHCCCCCEE
HVGQGVHVFHPETLQARLESLTGKKVLLDAGTSNAWFKLVLQNAGAVVVPGADPCLMPKA
ECCCCEEEECCHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCEEEECCCCCCCCCHH
AKNAVEISGMKACHLRDGAAMVKFLSWLDAQVAQGILHDEATLADKLEAIRREDPTLKDL
HCCCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCC
SFDTISAAGSNAAMCHYNHQNQPQPGQLSMDTLYLVDSGGQYLDGTTDITRTVAIGQPSA
CCHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEECCCHH
EMIKQFTLALKGHIGVARARFPKGTRGYQIDTLARQHLWAEGYDYDHGTGHGVGHFLSVH
HHHHHHHHHHHCCCCCHHHCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEC
EGPASISKRQIDVPLVEGMVLSNEPGYYRADAFGIRIENLELVVEKQTQGDFPILTFESL
CCCCCCCCCCCCCCHHCCEEEECCCCEEEECEEEEEEECEEEEEEECCCCCCCEEEHHHH
TRCPIDKRNINVDMLTRPELAWLNDYHQKVWDDISPLVEGDAQVWLREATLPLSH
HCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]